Combined Aortic and Mitral Balloon Valvuloplasty in Patients

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Combined Aortic and Mitral Balloon Valvuloplasty in Patients View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector ,*cc “0,. I I, NO. 6 1213 June 1WWXM METHODS Combined Aortic and Mitral Balloon Vahloplasty in Patients With Critical Aortic and Mitral Valve Stenosis: r(esults in Six Cases AARON D. BERMAN, MD, JOSEPH S. WEINSTEIN. MD. ROBERT D. SAFIAN, MD, DANIEL J. DIVER, MD, WILLIAM GROSSMAN. MD, FACC. RAYMOND G. MCKAY, MD Combined amtic and mifral valve disease may pose a dif- risk pzienis 01 in patients who refuse operarive intervex- ficult technical dilemma for the cardiac surgeon. Prolonged lion. peicllfaneous ballwn valvuloplasty was recently de- amtic cross clamp time, congestive heart failure aed eoex- scribed as etTective in pediatric patients (6.7) and adults istent coronary anay disease may all contribute 10 the !8-191 fo? both the aortic and the mitral valve. Krit-xr ad diflculty of operative and postotwative management of coworkers 120)recently reported successful performance of these patients. Investigators reporting early results (I) found a combined am-tic and mitral balloon vaivsbp!wy in an a significant operative mortality with dmble valve replace- elderly patient with combined aonic and mitral vale steno- ment. but since the advent of cold potassium cardioplegia. tis and severe heart failure. We herein repon our expertence the morbidity and mortality of this procedure have been in six patxots with eombincd awtic and mitral valve steno- markedly reduced (l-4). Nonetheless. patients with ad- sis. who uderwent successful simultaneous double valve vanced congestive heart failure continue to have pax short- balloon dilation. term survival (2.5). Otherassoeiated medical p&terns. such as renal. pulmonary or hepalic dysfunction. may also ad- Methods versely affect the outcome of patients undergoing double valve replacement. Miint chamteris4ii. Six patients with combined a(Klic As a nonsurgical alternative to valve replacement in high and mitral valve stenosis were referred 10 the Beth Israel Hospital for balloon valvuloplasty. Thar clinical character- istics and reasons for referral for balloon valvuloplasty rather than surgery weshowinTable 1. Patient Zalone was conrtdcred D good surgical candidate, but firmly refused any s:rgical intervention. Patient I had severe restrictive lung disease secondary to prior radiation therapy administered for breast carcinoma: in addition. she had undergone open mlt:at valve commissurotomy in 1978and had redeveloped rympbxn. Patient 3 was believed to be a high risk surgical candidate because of her advanced age. Patient 4 had retrograde and twnsseptal catheterization techniques advanced heart disease with pulmonary hypertension. se- G?-11.20).Although the aortic valve was dilated before the vere right heart Failure, cardiac cechexia and general debil- mitral valve in all but Patient 4. it was necessaryto perfarm ity. In addition, he had a dense right hemiparesis and the transseptal catheterization before aortic valvuloplasty to moderate aphasia as the residua of an embatic stroke ws- avoid anticoagulation before transseptal puncture was at- tained several years ago. and For these reasons. his surgical tempted. risk was believed to be prohibitively high. Patient 5 was also All patierds were premeditated with diw.epam and di. quite debilitated and had undergone previous coronary nr- phenhydraminc. Percutaneous right and left heart catheter- tew bypass surwy in 1982.Patient 6 had a hisrorv of dor ization was performed From the left femoral vein and left right them&e ~ncumolhoran for luberculorir~and~ had Femoral artery with a 7F pacing balloon flotation catheter mmterately severe restrictive and obs!mctive lune disease, (Elecath) and a 7F pigtail catheter, respectively. and a and hence was believed LObe a pour surgical candidate. weening oximetry study was performed. Next, tmnswptnl Table 2 shows kemodynnmic vnlucs in rheporienrs before catheterization was performed with a standard Brockm- valvrrloplnstyy.All patients had severe combined aortic and brough wedIe and an 8F Mullins sheath-dilator, which were mitral stenosis, and four OFthe six patients had a depressed advanced From the right femoral vein. After entry into the cardiac index. left atrium, a 7F balloon Rotation catheter (Ctitikon Inc.) Vahuloptasty prowlure. Combined aortic and mitral bal- was advanced through the Mullins sheath to the left atrium loon valvuloplasty pmcedures were performed with both and lO,ooOU otheparin was administered. AtIer tmnsseptal catheterization, the aortic valve was crowd retrograde by occasion. hemoptysir. It was believed that if the patient‘s way of the left femoral artery with a 0.035 in. <OS9 cm) pulmonary venous Blling oressure weld be lowered rud- straight guide wire passed thrwgh a 7F angled pigtail cdh- henly by rmtral valve dil%on. he would tolerate the rest of eter. The catheter was thee advanced over the wire into the the procedure with more comfort and less risk. left ventricle. Baseline hemodynamic variables and Fick cardiac outpot mewrement~ v&e recorded. Oxygen con- sumption ~3s measured with a commercial metabolic rate met&(Waters Instruments). Aarric ba/!oorr valv~rlo&~~ was then performed by Brst sdwncing a 270 cm, 0.038 in. (O.lOcm) I &p guide wire with surentents demonstrated a de&ax in both miti and aortic a handmade secondary curve into the left ventricle through valve gradients in all patients. Figure I shows the aortic and thc7F oigtail catheter and then removinnthc oktailcatheter. mmal gradients lor Patient 2 before and after valveloplasty. Next, the left femoral artery was dilated with ; IZF dilator, Cardmc ourpur. ncasured by the Fick technique. with use of anda9Fvalvulopiastycathcter withaZOmm balloon, 5Scm s metabolic rate meter (Waters Sciwiiic) to measureowan in length (Mansfield Inc.) was introduced over the guide wire consumption, increased sigoikxmtly in Patients 2.5 id 6. into the left ventricle. Calloon dilatioc of the aartic valve Left atrial preswre decreasedmarkedly in Patients 2.3 and was performed by h&on inflation with a dilute contrast- 6. These laxer three pa:ients also had the largest decreases saline mixture. and the aortic valvulopiasty catheter was in transmitral gradient and concomitant increases in mitral removed from the left ventricle. valve area, with wore ew&st results obtained in Patient I Afrcr aortic valve dilation, the 7F balloon Rotation cath- and 4 derpite the useof the double balloon technique in these eter in the left atrium was advanced into the left ventricle. A patients Patient I experienced an inc:eese in both right and 270 cm. 0.038 in. (0.10 em) J tip guide wire with a large ieft heart filling preswres after valvuloplasty. This increase handmade deflecting cone ~83 advanced through the 7F may have been related in part to the length of her procedure balloon Rotation catheter into the left ventricle and the 13 t IO mini and to the 1.800 ml of intravcnws Ruid she catheter and the Mullins sheath were removed. Next, an 8 received during the procedure. mm balloon dilation catheter (Mansfield. Inc.) V+BSadvanced Complkaticms mnltiag from tke praedore iTebk 3). No over this guide wire to the level of the inter&al septum. and complication resulted in significant mwbidity except for the multiple inRations were performed to dilate the septum. In femoral artery thrombus in Patient 3. for which catheter Patients Land 4, a double balloon technique was subs- thrombectom~ under local anesthesia was necessary. This m~nllv utilized for mival valve dilation. In these two procedure was p?rfoimed without complication. lo addition, &ients the 8 II balloon catheter was removed and B this patient had a left to right shunt et the atrial level with a second guide wire was placed across the atrird septum and pulmonary to systemic Row ratio of 1A:t. into the left ventricle with a 7F double lumen catheter Clinical fdkwap. ~ppkr-echcardiiphic studies af- (Manslielri, Inc.), which can accomodate two 0.038 in. (0.10 ter valvoioplasty demonstrated a decreasedgmdient across cm) guide wires. Two balloon dilation catheters (18 and 20 the aonic and mitral valves in all except Patient 3. with no mm in diawer, 3 em in length) were advanced separately. mtior increases in L3opplewJetectableregwgitation by two- one ~?er arh guide wire, aid positioned awo~s the mitral dimensional echocerdiographic pulsed LloQ&r mapping valve. Sisltaneou; intlations of the 18 and 20 mm balloons techniques. Regorgitation w&s not qoantitated ang&rephi- were thet: perfomwd. with a resulting reduction ofthe mitral tally because rmrtomems and ventricukwamo were not valve wad&t. In the four other patients. mitral valve pelformed before and after valwdoplasty a; a result of time dilation was performed with a single ballcon (25 mm i’l coostremts and the hemodyoamic conditions of many of the diameter, 3 cm in length). patients. Patient I to 3 and 6 were monitored after their After mirrul valve dilation. repeat measurementsof Fick procedures in the cardii intensive care unit for 24 h and cardiac output and traosvalvular sonic and mitral gradients were discharged from the hospital on the 4th day after -were wformed to essessvalve areas after valveloplast,‘. valvuloplasty. Patiems 4 and 5 required a longer recupera- After these measeremeets. oximetry was repeated to detect tion period but were discharged in markedly improved any iatmgenic left to right shunt. If such a shunt was condition after 2 weeks. detected. systemic Row war used in the valve area cakula- Patient I noted only modest improvement initially but lions. The mean duration of the valvslopiasty procedure vies after returning home. found that her exercise tolerance was 2.5 h (range 0.75 to 3. IJ. much improved with less palpitation and dyspnca. In eddi- In Patient 4. mitral balloon valvuloplasty was performed hon. she was ahte to undergo phammcologic conversion to before dilation of the uortic valve because this patient was normal sinus rhythm of lwrg-standing atrial fibrillation. Re- unable to lie Rat for more than a few minutes without peat Doppler-echocardiographic examir!ations 6 weeks after developing severe pulmonary wwos congestion and.
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