DOCSLIB.ORG

Phytochemical Characterization and Evaluation of Bioactive Properties of Tisanes Prepared from Promising Medicinal and Aromatic Plants

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Phytochemical Characterization and Evaluation of Bioactive Properties of Tisanes Prepared from Promising Medicinal and Aromatic Plants foods Article Phytochemical Characterization and Evaluation of Bioactive Properties of Tisanes Prepared from Promising Medicinal and Aromatic Plants Beatriz H. Paschoalinotto 1,2 , Maria Inês Dias 1,* , José Pinela 1 ,Tânia C.S.P. Pires 1 , Maria José Alves 1, Andrei Mocan 3,4 , Ricardo C. Calhelha 1 , Lillian Barros 1,* , Rafael P. Ineu 2 and Isabel C.F.R. Ferreira 1 1 Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal; [email protected] (B.H.P.); [email protected] (J.P.); [email protected] (T.C.S.P.P.); [email protected] (M.J.A.); [email protected] (R.C.C.); [email protected] (I.C.F.R.F.) 2 Universidade Tecnológica Federal do Paraná, Campus Campo Mourão (UTFPR-CM), Campo Mourão 87301-899, Brazil; [email protected] 3 Faculty of Pharmacy, “Iuliu Hat, ieganu” University of Medicine and Pharmacy, 8 Victor Babes, Street, 400012 Cluj-Napoca, Romania; [email protected] 4 Laboratory of Chromatography, Institute of Advanced Horticulture Research of Transylvania, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania * Correspondence: [email protected] (M.I.D.); [email protected] (L.B.); Tel.: +351-273-330-903 (M.I.D.) Abstract: The chemical composition and biological properties correlation in several medicinal and aromatic plants is still underexplored, especially in its most common form of consumption as tisane. Citation: Paschoalinotto, B.H.; Dias, The present study aims to characterize the organic acids and vitamin E composition of five tisanes M.I.; Pinela, J.; Pires, T.C.S.P.; Alves, and their extracts by High-Performance Liquid Chromatography coupled to a diode-array detector M.J.; Mocan, A.; Calhelha, R.C.; (HPLC-DAD) and HPLC coupled to a fluorescence detector techniques, respectively, and the phenolic Barros, L.; Ineu, R.P.; Ferreira, I.C.F.R. composition by HPLC-DAD-ESI/MS (mass spectrometry by electrospray ionization). It also focuses Phytochemical Characterization and on their bioactive properties, namely antioxidant, antimicrobial, anti-inflammatory, cytotoxic, anti- Evaluation of Bioactive Properties of tyrosinase, and anti-diabetic activities. A Principal Component Analysis (PCA) was performed in Tisanes Prepared from Promising order to understand the correlation between the chemical composition and bioactive properties of Medicinal and Aromatic Plants. Foods the tisanes. The tisane 5 (T5) composed by lemon thyme, tutsan, cloves, and cinnamon, was the 2021, 10, 475. https://doi.org/ 10.3390/foods10020475 most promising mixture, presenting the lowest values for the lipid peroxidation inhibition, anti- inflammatory, and anti-diabetic activity. It also presented the highest concentration of phenolic Academic Editor: Rubén Domínguez acids (caffeoylquinic acids derivatives), and flavan-3-ols (catechin derivatives). Only the dry plants presented tocopherols. For the antihemolytic, antimicrobial, and cytotoxic activity, T2 and T4 (with Received: 26 January 2021 lemon thyme) were highlighted as the best herbal mixtures. The PCA proved to be a valid tool to Accepted: 19 February 2021 select the most promising tisane according to the bioactivity. These results suggest that the studied Published: 22 February 2021 tisanes can be source of high added-value bioactive compounds with health-promoting effects and potential for application in the food and nutraceutical industries, among others. Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in Keywords: medicinal and aromatic plants; herbal teas; tisane; phenolic compounds; bioactives published maps and institutional affil- iations. 1. Introduction Currently, there is a growing interest in medicinal and aromatic plants (MAPs) due to Copyright: © 2021 by the authors. the various benefits they provide to consumers’ health. MAPs, as natural sources of several Licensee MDPI, Basel, Switzerland. bioactive compounds, have medicinal properties with great potential to be applied for the This article is an open access article treatment of several diseases [1]. Their most common form of consumption is as tisane, or distributed under the terms and popularly known as herbal teas or infusions [2]. conditions of the Creative Commons The active roles of several MAPs upon disease prevention, control, or reduction have Attribution (CC BY) license (https:// been attributed to the antioxidant features of lypossoluble constituents (such as vitamins creativecommons.org/licenses/by/ 4.0/). A and E), water-soluble components (such as vitamin C and organic acids), and phenolic Foods 2021, 10, 475. https://doi.org/10.3390/foods10020475 https://www.mdpi.com/journal/foods Foods 2021, 10, 475 2 of 26 compounds [3–6]. The antioxidant activity of phenolic compounds is mainly due to their redox properties, which allow them to act as reducing agents and hydrogen donators [7]. The characterization of phenolic compounds responsible for the different beneficial prop- erties identified is of great interest for the food and nutraceutical industries, focusing on numerous applications, such as replacement of artificial antioxidants, development of food supplements, or nutraceuticals, among others [8,9]. There are several studies indicating that mixtures of MAPs are potentially more bioactive when compared to isolated plants [9,10]. However, the therapeutic properties that tisanes prepared from MAPs mixtures may exhibit are still under-explored. In this context, the present study describes the chemical composition in terms of phenolic compounds, organic acids, and tocopherols (vitamin E) of five tisanes prepared from mixtures of distinct MAPs. Furthermore, the antioxidant, antimicrobial, anti-inflammatory, cytotoxic, anti- tyrosinase, and antidiabetic activities of the five tisanes were also evaluated and correlated with the presence of the several families of phenolic compounds found. The results obtained could add value to these tisanes with the potential to be applied in different industrial sectors. 2. Materials and Methods 2.1. Samples and Tisanes Preparations Five tisane samples (Figure1) were kindly provided by the “Cantinho das Arom áticas” Company, Canidelo—Vila Nova de Gaia, Portugal, in their commercial form (dried and packed in plastic wrappers). Tisane one (T1) was composed by Cymbopogon citratus (D.C.) Stapf, Ocimum basilicum “Cinnamon”, and Gomphrena sp.; tisane two (T2) had Thymus x citriodorus (Pers.) Schreb, Thymus mastichina L., Lavandula angustifolia Mill, and Gomphrena globosa L.; tisane three (T3) was composed by Agastache foeniculum (Pursh) Kuntze, Mentha x piperita L., and Mentha spicata L.; tisane four (T4) had Rosmarinus officinalis L., Ocimum basilicum L., Thymus x citriodorus (Pers.) Schreb, Calendula officinalis L., and Mentha x piperita L.; finally, tisane five (T5) was composed by Hypericum androsaemum L., Thymus x citriodorus (Pers.) Schreb, Cinnamomum zeylanicum Blume, and Syzygium aromaticum L. The MAPs that make up the tisanes were produced following the principles of organic production (certified by ECOCERT, Leiria, Portugal) and do not contain caffeine (information provided by the company). Some of the biological activities that the studied plants exhibits are described in Table1. The dried samples were reduced to a fine homogeneous powder (~20 mesh) and stored in a cool dry place. The tisanes were prepared by adding 2 g of each dried sample to 50 mL of boiling distilled water (100 ◦C), allowing them to stand for 5 min at room temperature and then filtering them through a filter paper. The obtained tisanes were frozen and lyophilized, then stored in a dry place at room temperature and protected from light before further analysis. Foods 2021, 10, x FOR PEER REVIEW 2 of 24 A and E), water-soluble components (such as vitamin C and organic acids), and phenolic compounds [3–6]. The antioxidant activity of phenolic compounds is mainly due to their redox properties, which allow them to act as reducing agents and hydrogen donators [7]. The characterization of phenolic compounds responsible for the different beneficial prop- erties identified is of great interest for the food and nutraceutical industries, focusing on numerous applications, such as replacement of artificial antioxidants, development of food supplements, or nutraceuticals, among others [8,9]. There are several studies indicating that mixtures of MAPs are potentially more bio- active when compared to isolated plants [9,10]. However, the therapeutic properties that tisanes prepared from MAPs mixtures may exhibit are still under-explored. In this con- text, the present study describes the chemical composition in terms of phenolic com- pounds, organic acids, and tocopherols (vitamin E) of five tisanes prepared from mixtures of distinct MAPs. Furthermore, the antioxidant, antimicrobial, anti-inflammatory, cyto- toxic, anti-tyrosinase, and antidiabetic activities of the five tisanes were also evaluated and correlated with the presence of the several families of phenolic compounds found. The results obtained could add value to these tisanes with the potential to be applied in dif- ferent industrial sectors. 2. Materials and Methods 2.1. Samples and Tisanes Preparations Five tisane samples (Figure 1) were kindly provided by the “Cantinho das Aromát- icas” Company, Canidelo—Vila Nova de Gaia, Portugal, in their commercial form (dried and packed in plastic wrappers). Tisane one (T1) was composed by Cymbopogon citratus (D.C.) Stapf, Ocimum basilicum “Cinnamon”, and Gomphrena sp.; tisane two (T2)
Load more

Recommended publications
  • Analgesic-Like Activity of Essential Oil Constituents: an Update
    International Journal of Molecular Sciences Review Analgesic-Like Activity of Essential Oil Constituents: An Update Rita de Cássia da Silveira e Sá 1, Tamires Cardoso Lima 2, Flávio Rogério da Nóbrega 3, Anna Emmanuela Medeiros de Brito 3 and Damião Pergentino de Sousa 3,* ID 1 Departamento de Fisiologia e Patologia, Universidade Federal da Paraíba, CP 5009, João Pessoa-PB 58051-970, Brazil; [email protected] 2 Departamento de Farmácia, Universidade Federal de Sergipe, São Cristóvão-SE 49100-000, Brazil; [email protected] 3 Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, João Pessoa-PB 58051-970, Brazil; [email protected] (F.R.N.); [email protected] (A.E.M.B.) * Correspondence: [email protected]; Tel.: +51-83-3209-8417 Received: 23 October 2017; Accepted: 3 November 2017; Published: 9 December 2017 Abstract: The constituents of essential oils are widely found in foods and aromatic plants giving characteristic odor and flavor. However, pharmacological studies evidence its therapeutic potential for the treatment of several diseases and promising use as compounds with analgesic-like action. Considering that pain affects a significant part of the world population and the need for the development of new analgesics, this review reports on the current studies of essential oils’ chemical constituents with analgesic-like activity, including a description of their mechanisms of action and chemical aspects. Keywords: analgesic; antinociceptive; terpenes; phenylpropanoid; natural products; medicinal plants; aromas; flavor; volatile; food 1. Introduction Constituents of essential oils are commonly found in foods giving characteristic aroma and flavor. Several plants and their fruits can be recognized by the aroma provided by volatile substances, which are generally alcohols, aldehyde ketones, esters, hydrocarbons, phenols, among other chemical classes.
    [Show full text]
  • Bulletin of the UC Santa Cruz Arboretum & Botanic Garden
    Bulletin of the UC Santa Cruz Arboretum & Botanic Garden NEWSLETTER FOR ARBORETUM MEMBERS & FRIENDS ARBORETUM.UCSC.EDU / [email protected] VOLUME 43, ISSUE 1 SUMMER 2018 New South African AustralianArboretum New Zealand California Native Aroma/Succulent Butterfly Garden Garden Garden Garden Gardens Garden A Great Time to Visit Contents Mid-summer in the gardens— From the Staff / Save the Date …………. 1 foggy mornings, brilliant afternoons. When the sea mist People in the News ……………………… 2 evaporates, the air becomes Plant Conservation Programs ………….. 3 golden. A day in the gardens is On the Shelf: Book Review …………….. 5 a progression of cool to hot, of birds ranging from raucous to Plant Q&A: Sage vs Salvia ……………… 6 silent, of changing light angles, Buy Local: Garden Centers …………….. 7 and fragrant breezes. Meanwhile, despite welcoming more daily visitors than ever, things seem quiet, a Kew Gardens’ 2017 Report …………..… 7 month or two without major events. But we are as Gallery of Photos ………………………… 8 busy as ever, weeding and pruning, labeling and watering. It’s a great time to hang out with us. New at the Arboretum …………………… 9 —Martin Quigley Staff & Board Members / Contacts ……. 10 Executive Director Calendar of Events ………………………. 11 Donor/Membership Updates & Thank You .. 12 Annual Membership Meeting (Arb-B-Q): September 16 4-7 pm Fall Plant Sale with CNPS October 13 Members: 10 am-12 pm Public: 12-4 pm Auction: 3-4 pm Leucospermum glabrum x conocarpodendron SUMMER 2018 BULLETIN 2 Helen Englesberg Says Goodbye! On June 30, Helen Englesberg, the Arboretum’s wonderful Nursery Manager, retired. Her almost thirty year career began while she was studying Biology/Plant Sciences at UCSC and joined the staff as a student employee.
    [Show full text]
  • Research Design and General Objectives
    Forest quality in the southwest of Mexico City. Assessment towards ecological restoration of ecosystem services Thesis submitted in partial fulfilment of the requirements of the degree Doctor rer. nat. of the Faculty of Forest and Environmental Sciences, Albert-Ludwigs-Universität Freiburg im Breisgau, Germany By Víctor Ávila-Akerberg Freiburg im Breisgau, Germany 2009 Dean: Prof. Dr. Heinz Rennenberg First supervisor: Prof. Dr. Werner Konold Second supervisor: Prof. Dr. Albert Reif Date of disputation: December 9th 2009 Acknowledgements This thesis is dedicated to the forests in the area under study and to my family and friends! Thanks to Dr. Werner Konold, for accepting me as a PhD student, having trusted on my research, for always being there whenever I needed him, and for encouraging and supporting my trips to courses and conferences around the world, vielen Dank! I would like to thank Dr. Albert Reif for being my second supervisor and for the given advice and comments on the thesis. I would like to thank Dr. Lucia Almeida, for having taught me so many things, for believing in me and together having achieved so much in the Magdalena river watershed. My great appreciation goes to Dr. Jorge Meave del Castillo, for advising me and have shared part of his enormous experience and patience on scientific writing. Special thanks go to Esther Muschelknautz, for always being there to answer the administrative questions, attending and organizing the milestones and the extra- curricular courses in the International PhD Program “Forestry in transition”. During the last three years of my life, I have met and shared moments with many wonderful persons.
    [Show full text]
  • Catalogue of Plant Collections
    čistý formát 163x235 mm 10907_CatalogueOfPlantCollections7_C5_V2_120s_LL_OBALKA CATALOGUE OF PLANT COLLECTIONS No. 7 CATALOGUE OF PLANT COLLECTIONS No. 7 1950 2020 70 YEARS BOTANICAL GARDEN OF P. J. ŠAFÁRIK UNIVERSITY IN KOŠICE DOI: https://doi.org/10.33542/COP2020-884-2 KOŠICE 2020 ISBN 978-80-8152-883-5 (PRINT) ISBN 978-80-8152-884-2 (ONLINE) Slovakia Pavol Jozef Šafárik University in Košice, Slovakia Botanical Garden CATALOGUE OF PLANT COLLECTIONS No. 7 Košice 2020 Slovakia Catalogue of Plant Collections No. 7 Botanical Garden of Pavol Jozef Šafárik University, Košice, Slovakia Editors: Lenka Mártonfiová Pavol Mártonfi Contributors: Robert Gregorek Peter Kelbel Pavol Mártonfi Lenka Mártonfiová Michal Vasiľ Photos: Lenka Mártonfiová Cover: Andrea Fridmanová © 2020 Pavol Jozef Šafárik University in Košice All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form without the permission of the owners of the rights. Localization: https://unibook.upjs.sk/sk/ Available since: 3rd Sept. 2020 DOI: https://doi.org/10.33542/COP2020-884-2 ISBN 978-80-8152-883-5 (PRINT) ISBN 978-80-8152-884-2 (ONLINE) Introduction The Botanical Garden of Pavol Jozef Šafárik University in Košice was established on May 5, 1950, and in 2020 it commemorates the 70th anniversary of its establishment. It is a part of the university and it represents its scientific and pedagogical workplace. At present, it is the largest botanical garden in Slovakia with an area of 30 ha and 3500 m2 of greenhouses. The Botanical Garden is a large green area of the metropolis of eastern Slovakia, the town of Košice.
    [Show full text]
  • FILOGENIA E DIVERSIDADE GENÉTICA DO GÊNERO Cunila D. Royen Ex L., (Lamiaceae). Gustavo Agostini
    UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL DEPARTAMENTO DE BOTÂNICA PROGRAMA DE PÓS-GRADUAÇÃO EM BOTÂNICA FILOGENIA E DIVERSIDADE GENÉTICA DO GÊNERO Cunila D. Royen ex L., (Lamiaceae). Gustavo Agostini Tese apresentada ao Programa de Pós- Graduação em Botânica da Universidade Federal do Rio Grande do Sul, como parte dos requisitos para a obtenção do título de Doutor em Ciências: Botânica. ORIENTADORA: Profa. Dra. TATIANA TEIXEIRA DE SOUZA-CHIES CO-ORIENTADOR: Prof. Dr. SERGIO ECHEVERRIGARAY Porto Alegre – RS 2008 “... E AI TRANQUEIRA!!!” (Dr. Sergio) II Aos meus amados pais, Miguel e Rejane, ao meu amor Tanara. III AGRADECIMENTOS Um doutorado gera além de conhecimento científico, amizades e parcerias. Muitas pessoas contribuíram para o desenvolvimento deste trabalho, de diversas maneiras. Em especial agradeço: À Tatiana Teixeira de Souza-Chies, minha orientadora, prima, amiga, incentivadora e “cobradora”. Agradeço pela confiança, cumplicidade, idéias e pela agenda para lembrar meus compromissos, esta confesso que nunca usei, pois, não lembro onde guardei. Obrigado Tati !! Ao meu co-orientador, Sergio Echeverrigaray, agradeço pela luz, pela infinita paciência de “pai”, amizade, pelos conselhos, pelos cafés, jantas, risadas, agradeço não só por estes quatro últimos anos, mas sim pelos doze. Aos professores e colegas do PPG Botânica pelo aprendizado e companheirismo durante estes anos, em especial ao professor Dr. Geraldo Soares pelo interesse e amizade. Ao Dr. Bordignon, pelas coletas, identificações de espécies e sobretudo pelo interesse e incentivo. Aos colegas de “cunilalogia”, Jucimar Carpete Zacaria, Fernando Galioides Fracaro, Felipe Bothrops Grazziontin, um especial MUITO OBRIGADO. À minha irmã Msc Fabiana Agostini e sua dedicada bolsista Paula pela ajuda incansável com as extrações de óleos.
    [Show full text]
  • Lamiaceae): a Taxonomically Enigmatic and Critically Endangered Genus
    Li & al. • Phylogenetic position of Wenchengia TAXON 61 (2) • April 2012: 392–401 Phylogenetic position of Wenchengia (Lamiaceae): A taxonomically enigmatic and critically endangered genus Bo Li,1,7 Weixiang Xu,2 Tieyao Tu,1 Zhongsheng Wang,2 Richard G. Olmstead,3 Hua Peng,4 Javier Francisco-Ortega,5 Philip D. Cantino6 & Dianxiang Zhang1 1 Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, the Chinese Academy of Sciences, Guangzhou 510650, Guangdong, China 2 Laboratory of Forest Ecology and Global Change, School of Life Science, Nanjing University, Nanjing 210093, Jiangsu, China 3 Department of Biology and Burke Museum, University of Washington, Box 355325, Seattle, Washington 98195-5325, U.S.A. 4 Key Laboratory of Biodiversity and Biogeography, Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming 650204, Yunnan, China 5 Department of Biological Sciences, Florida International University, and Fairchild Tropical Botanic Garden, Miami, Florida 33199, U.S.A. 6 Department of Environmental and Plant Biology, Ohio University, Athens, Ohio 45701-2979, U.S.A. 7 Graduate University of the Chinese Academy of Sciences, Beijing 100049, China Author for correspondence: Dianxiang Zhang, [email protected] Abstract The phylogenetic position of the monotypic genus Wenchengia has long been controversial. It variously has been assigned to a monotypic subfamily Wenchengioideae, treated as a member of subfamily Scutellarioideae, or suggested to be related to Lamioideae or Ajugoideae. The recent rediscovery of Wenchengia alternifolia from its type locality provided an opportunity to infer its phylogenetic position using evidence from two plastid DNA regions (rbcL, ndhF), morphological data, and anatomical and cytological characters.
    [Show full text]
  • Aromatic and Medicinal Plants in Mexico Aromatic and Medicinal Plants in Mexico
    Provisional chapter Chapter 7 Aromatic and Medicinal Plants in Mexico Aromatic and Medicinal Plants in Mexico Mariana Palma-Tenango, Ruben San Mariana Palma-Tenango, Miguel-Chávez and Ramón Marcos Soto-HernándezRuben San Miguel-Chávez and Ramón Marcos Soto-Hernández Additional information is available at the end of the chapter Additional information is available at the end of the chapter http://dx.doi.org/10.5772/66507 Abstract Medicinal and aromatic plants in Mexico have been studied and explored through his- tory. Day by day there is an increase in ethnobotanical, taxonomic, or phytochemical studies, providing an encouraging picture of research in Mexico and to support its use in traditional medicine. Chemical and biological exploration permit to provide solutions to the treatment of diseases. With this background, the objective of this chapter is to show the potential of endemic medicinal and aromatic plants in Mexico. Keywords: endemic, medicinal herbs, Mexico 1. Introduction Mexico is a country with a wide variety of medicinal and aromatic plants; their use is rooted in its culture, and they are employed to solve health problems in areas with little access to medicines. Although there are several introduced species, Mexico has a high number of endemic plants that are considered medicinal. Demand for medicinal plants increases with the market, which is broad [1]. They are plants that produce secondary metabolites, each with different active ingredients and different ther- apeutic properties [2]. However, phytochemical information is generally focused on intro- duced species. Mexico has medicinal and aromatic species that require scientific research and wider dissemination. The cultivated area in the country is smaller than the demand there, and most of the plants are grown commercially.
    [Show full text]
  • Resumen Abstract
    MARTHA MARTÍNEZ-GORDILLO1, BRENDA BEDOLLA-GARCÍA2, GUADALUPE CORNEJO- TENORIO3, ITZI FRAGOSO-MARTÍNEZ4*, MARÍA DEL ROSARIO GARCÍA-PEÑA4, JESÚS GUADALUPE GONZÁLEZ-GALLEGOS5, SABINA I. LARA-CABRERA6 Y SERGIO ZAMUDIO7 Botanical Sciences 95 (4): 780-806, 2017 Resumen Antecedentes: Lamiaceae es una de las familias con mayor riqueza de especies en México. Sin embargo, aún se carece de un estudio detallado sobre su diversidad en el país y de una revisión taxonómica global y actualizada. DOI: 10.17129/botsci.1871 Como resultado, el aprovechamiento y conservación de los integrantes de esta familia es limitado. Received: Preguntas: ¿Qué avances se han logrado en el estudio y entendimiento de la riqueza, endemismo y distribución 2 de octubre de 2017 de las Lamiaceae mexicanas? ¿Qué estrategias deben ejecutarse para consolidar el conocimiento de la familia Accepted: en el país? 10 de noviembre de 2017 Taxon: Lamiaceae Associate Editor: Guillermo Sitio de estudio: México Ibarra Manriquez Métodos: Se hizo una revisión exhaustiva de las Lamiaceae mexicanas en la literatura, bases de datos y her- barios. Se sintetizó el estado de su conocimiento. Se aplicaron análisis cuantitativos para evaluar su riqueza, endemismo y distribución geográfca. Resultados: México cuenta con 33 géneros y 598 especies, de las cuales el 66.2 % son endémicas. El género Copyright: © 2017 Martínez-Gor- dillo et al. This is an open access más diverso es Salvia, con 306 especies. El estado más diverso es Oaxaca, mientras que Jalisco alberga el mayor article distributed under the terms of número de especies endémicas. the Creative Commons Attribution Conclusiones: En México, Lamiaceae es la octava familia más diversa y el número de sus especies representa el License, which permits unrestricted 5.5 % de la familia a nivel mundial, por lo que el país puede considerarse uno de los centros de diversifcación use, distribution, and reproduction más importante.
    [Show full text]
  • Mexican Plants and Derivates Compounds As Alternative for Inflammatory and Neuropathic Pain Treatment—A Review
    plants Review Mexican Plants and Derivates Compounds as Alternative for Inflammatory and Neuropathic Pain Treatment—A Review Geovanna N. Quiñonez-Bastidas * and Andrés Navarrete * Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, Ciudad de México 04510, Mexico * Correspondence: [email protected] (G.N.Q.-B.); [email protected] (A.N.); Tel.: +52-5556225291 (A.N.) Abstract: Despite the availability of many anti-pain drugs, in the form of NSAIDs, steroids, gabapenti- noids, opioids, and antidepressants, in this study we address the natural compounds belonging to the group of Mexican medicinal plants or “Mexican folk medicine”, used for pain management in Mexico. Our interest in this subject is due to the growing idea that “natural is harmless” and to the large number of side effects exhibited in pharmacotherapy. The objective of this review was to document the scientific evidence about Mexican medicinal plants and their derivatives used for inflammatory and neuropathic pain treatment, as well as the mechanisms of action implicated in their antinociceptive effects, their possible adverse effects, and the main pharmacological aspects of each plant or compound. Our data review suggested that most studies on Mexican medicinal plants have used inflammatory experimental models for testing. The anti-pain properties exerted by medicinal plants lack adverse effects, and their toxicological assays report that they are safe to consume; therefore, more studies should be performed on preclinical neuropathic pain models. Citation: Quiñonez-Bastidas, G.N.; Moreover, there is no convincing evidence about the possible mechanisms of action involved in Navarrete, A. Mexican Plants and the anti-pain properties exerted by Mexican plants.
    [Show full text]
  • Aromatic and Medicinal Plants in Mexico
    Chapter 7 Aromatic and Medicinal Plants in Mexico Mariana Palma-Tenango, Ruben San Mariana Palma-Tenango, Miguel-Chávez and Ramón Marcos Soto-HernándezRuben San Miguel-Chávez and Ramón Marcos Soto-Hernández Additional information is available at the end of the chapter Additional information is available at the end of the chapter http://dx.doi.org/10.5772/66507 Abstract Medicinal and aromatic plants in Mexico have been studied and explored through his- tory. Day by day there is an increase in ethnobotanical, taxonomic, or phytochemical studies, providing an encouraging picture of research in Mexico and to support its use in traditional medicine. Chemical and biological exploration permit to provide solutions to the treatment of diseases. With this background, the objective of this chapter is to show the potential of endemic medicinal and aromatic plants in Mexico. Keywords: endemic, medicinal herbs, Mexico 1. Introduction Mexico is a country with a wide variety of medicinal and aromatic plants; their use is rooted in its culture, and they are employed to solve health problems in areas with little access to medicines. Although there are several introduced species, Mexico has a high number of endemic plants that are considered medicinal. Demand for medicinal plants increases with the market, which is broad [1]. They are plants that produce secondary metabolites, each with different active ingredients and different ther- apeutic properties [2]. However, phytochemical information is generally focused on intro- duced species. Mexico has medicinal and aromatic species that require scientific research and wider dissemination. The cultivated area in the country is smaller than the demand there, and most of the plants are grown commercially.
    [Show full text]
  • Ethnomedicinal Plants Used for the Treatment of Dermatological Affections on the Purépecha Plateau, Michoacán, Mexico Flora Et
    125: 95-132 October 2018 Research article Ethnomedicinal plants used for the treatment of dermatological affections on the Purépecha Plateau, Michoacán, Mexico Flora etnomedicinal utilizada para el tratamiento de afecciones dermatológicas en la Meseta Purépecha, Michoacán, México Roberto Esquivel-García1 , Emmanuel Pérez-Calix2 , Alejandra Ochoa-Zarzosa3 Martha-Estrella García-Pérez1,4 ABSTRACT: 1 Universidad Michoacana de San Ni- Background and Aims: Inhabitants of the Purépecha Plateau preserve an excellent ancestral knowledge colás de Hidalgo, Facultad de Quí- on medicinal plants used for dermatological affections, which has not been documented. An ethnophar- mico Farmacobiología, Morelia, Mi- choacán, Mexico. macological survey was carried out in this region to gather information on the use of medicinal plants 2 Instituto de Ecología, A.C., Red de and herbal preparations for treating dermatological affections, to disseminate the Purépecha indigenous Diversidad Biológica del Occidente knowledge and identifying promising plants for developing new formulations for cutaneous conditions. Mexicano, Pátzcuaro, Michoacán, Methods: The study was conducted in the 21 municipalities that compose the Purépecha Plateau. A total Mexico. of 86 local inhabitants (62 women and 24 men) were interviewed. The data were quantitatively analyzed 3 Universidad Michoacana de San Ni- through the determination of the use value, fidelity level and informant consensus factor. colás de Hidalgo, Centro Multidisci- Key results: A total of 97 plant species belonging to 47 families were documented for treating 19 der- plinario de Estudios en Biotecnolo- gía-Facultad de Medicina Veterinaria matological conditions on the Purépecha Plateau. Asteraceae was the leading family among the collec- y Zootecnia, Tarímbaro, Michoacán, ted medicinal plants (20.61%), followed by Lamiaceae (13.40%) and Solanaceae (5.15%).
    [Show full text]