Amniotic Fluid Learning Objectives
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Thomas Addis (1881—1949): Mixing Patients, Rats, and Politics
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector Kidney International, Vol. 37 (1990), pp. 833—840 HISTORICAL ARCHIVE CARL W. GOi-FSCHALK, EDITOR Thomas Addis (1881—1949): Mixing patients, rats, and politics STEVEN J. PEITZMAN Department of Medicine, Division of Nephrology and Hypertension, The Medical College of Pennsylvania, Philadelphia, Pennsylvania, USA In the early decades of the twentieth century, with the threatat the Laboratory of the Royal College of Physicians of Edin- of epidemic infectious diseases already in decline, attentionburgh, one of Great Britain's pioneering medical research shifted to the chronic maladies: hypertension, atherosclerosis,enterprises, also supported by the Carnegie Trusts. obesity, cancer, diabetes—and nephritis, or Bright's disease. Ray Lyman Wilbur (1875—1949), dean of the young Stanford New chemical methods devised by Otto Folin (1867—1934) atMedical School in 1911, "thought it would be a good thing to Harvard and Donald D. Van Slyke (1883—1971) at the Rock-bring in a young scientist from Scotland if the right one could be efeller Institute Hospital empowered the investigation of renalfound who had been trained in German as well as British and metabolic disorders. Folin's colorimetric system provideduniversities, and who was likely to develop in some promising rapid measurement of creatinine, urea, and uric acid, while Vanfield of research" [3]. So Wilbur sent a cable of invitation to Slyke's gasometric analyses allowed quantification of urea andEdinburgh, and the young Scotsman accepted the unlikely total carbon dioxide. Also in the first decades of the twentiethposition: in 1911 Stanford was still a relatively isolated and century, the reform of medical schools provided new opportu-little-known medical school in San Francisco (the school moved nities for academic medical careers. -
Simplified Quantitative Methods for Bacteriuria and Pyuria
J Clin Pathol: first published as 10.1136/jcp.16.1.32 on 1 January 1963. Downloaded from J. clin. Path. (1963), 16, 32 Simplified quantitative methods for bacteriuria and pyuria JAMES McGEACHIE AND ARTHUR C. KENNEDY From the University Departments of Bacteriology and Medicine, Royal Infirmary, Glasgow SYNOPSIS Although pyelonephritis is a common disease, it escapes clinical detection in an un- desirably high proportion of patients. The present unsatisfactory diagnostic position would be much improved by widespread screening of patients by simple yet reasonably accurate methods. Bacterial counts by the pour-plate technique and estimates of the white cell excretion per hour or day, while undoubtedly of diagnostic value, are probably unsuitable for use on a wide scale. In an attempt to find more convenient procedures a simplified stroke-plate method of bacterial counting and a simplified quantitative white cell count method were devised and applied to over 1,000 mid-stream urine samples from 398 patients. Good correlation was obtained between the simpler stroke-plate method of bacterial counting and the more time-consuming pour-plate method. The quantitative white cell procedure was a much more sensitive index of pyuria than wet-film micro- scopy, and comparison with the bacterial count results showed that it gave a useful indication of urinary infection. It is suggested that a quantitative bacterial count should replace non-quantitativecopyright. culture methods when urinary infection is suspected and that the quantitative white cell count should be performed as a routine part of the initial clinical and laboratory assessment of all patients, followed by a bacterial count if pyuria is revealed. -
Usmle Rx Qbank 2017 Step 1 Renal
Item: 1 of 24 ~ 1 • M k -<:J 1>- Jil ~· !:';-~ QIO: 4749 ..L a r Previous Next Labfli!llues Not es Calculat o r • 1 & & A 67-year-old man admitted for postoperative recovery is found to be oliguric. Laboratory studies show a blood urea nitrogen level of 200 • 2 mg/dl and a serum creatinine level of 6 mg/dl. Urinalysis shows: • 3 Specific gravity: 1.050 · 4 Urine osmolality: 670 mOsm/kg • 5 Sodium: 14 mEq/L BUN/Creatinine ratio: 56 • 6 Fractional excretion of Na: 0.54% • 7 Protein: negative Casts: negative · 8 . 9 • 10 Which of the following is the most likely cause of this patient's oliguria? • 11 : • 12 A. Acute interstitial nephritis • 13 B. Acute tubular necrosis • 14 C. Bladder calculus • 15 • 16 D. Heart failure • 17 E. Nephrotic syndrome • 18 • 19 • 20 • 21 • a s 8 Lock Suspend End Block Item: 1of24 ~ . , . M k <:] t> al ~· ~ QIO: 4749 .l. ar Previous Next Lab'lifllues Notes Calculator 1 • The correct a nswer is 0. 4 80/o c hose t his. • 2 This patient's laboratory tests confirm the classic criteria for d iagnosing prerenal azotemia. Prerenal azotemia is caused by a reduction of the • 3 g lomerular filtration rate (GFR} provoked by an insult to the vascular supply to the kidney. Causes of prerenal azotemia include heart failure, sepsis, and renal artery stenosis. The reduction in GFR increases the accumulation of both blood urea nitrogen (BUN} and creatinine (Cr} in the • 4 blood, but because the BUN concentration in blood is determined by both g lomerular filtration and reabsorption (in contrast to Cr, which is • 5 limited to filtration and not reabsorbed}, the BUN level rises out of proportion to the Cr leveL This therefore elevates the BUN :Cr ratio. -
Name: Akinbile Grace Oluwaseun Matric Number
NAME: AKINBILE GRACE OLUWASEUN MATRIC NUMBER: 18/MHS02/029 DEPARTMENT: NURSING, MHS COURSE CODE: PHS 212 (PHYSIOLOGY) ANSWER URINALYSIS Urinalysis is the process of analysing urine for target parameters of health and disease. A urinalysis (UA), also known as routine and microscopy (R&M), is an array of tests performed on urine, and one of the most common methods of medical diagnosis. Urinalysis means the analysis of urine, and it is used to diagnose several diseases. The target parameters that are measured or quantified in urinalysis include many substances and cells, as well as other properties, such as specific gravity. A part of a urinalysis can be performed by using urine test strips, in which the test results can be read as the strip’s colour changes. Another method is light microscopy of urine samples. Test Strip Urinalysis Test strip urinalysis exposes urine to strips that react if the urine contains certain cells or molecules. Test strip urinalysis is the most common technique used in routine urinalysis. A urine test strip can identify: Leukocytes—their presence in urine is known as leukocyturia. Nitrites—their presence in urine is known as nitrituria. Proteins —their presence in urine is known as proteinuria, albuminuria, or micro albuminuria. Blood—its presence in urine is known as haematuria. pH—the acidity of urine is easily quantified by test strips, which can identify cases of metabolic acidosis or alkalosis. Urine Microscopy The numbers and types of cells and/or material, such as urinary casts, can yield a great detail of information and may suggest a specific diagnosis. -
Cardiovascular II 10:30 AM Saturday, February 23, 2019
Abstracts J Investig Med: first published as 10.1136/jim-2018-000974.619 on 28 January 2019. Downloaded from 669 NITRIC OXIDE SYNTHASE INHIBITION STIMULATES diagnostic information otherwise not identified in a single RENIN SYNTHESIS INDEPENDENT OF CGMP IN inspection. COLLECTING DUCT CELLS Methods used Microscopic examination of the urinary sedi- 1 1 1 1 1 2 ment (MicrExUrSed)±Sternheimer Malbin stain was under- A Curnow*, SR Gonsalez, B Visniauskas, SL Crabtree, VR Gogulamudi, EE Simon, 3Lara Morcillo Ld, 1,4MC Prieto. 1Tulane University-SOM, New Orleans, LA; 2Tulane taken in all patients with AKI stage 2 who were seen on University HSC, New Orleans, LA; 3Instituto de Biofisica Chagas Filho, Universidade Federal consultation in an inpatient nephrology service during a do Rio de Janeiro, Rio de Janeiro, Brazil; 4Tulane Hypertension and Renal Center of 6 month period. MicrExUrSed were done on the day of con- Excellence, Tulane University, New Orleans, LA sult (day 1), 48 hours later (day 3) and 96 hours later (day 5). Urinary cast scores (based on Chawla et al and Perazella 10.1136/jim-2018-000974.675 et al) were assigned to each specimen. Chawla scores (CS) 3– 4 and Perazella scores (PS) 2–3 were categorized as consistent Purpose of study Nitric oxide (NO) synthase (NOS) inhibitors with acute tubular injury (ATI), whereas CS 1–2 and PS 0–1 attenuate any stimulation of juxtaglomerular renin gene were categorized as non-diagnostic for ATI (non-ATI). Worsen- expression, regardless of the underlying challenge of the ing AKI was defined as a rise in serum creatinine renin-angiotensin system. -
Schedule of Benefits for Laboratory Services
SCHEDULE OF BENEFITS For LABORATORY SERVICES April 1, 1999 LABORATORY MEDICINE PREAMBLE: SPECIFIC ELEMENTS In addition to the common elements, (see General Preamble to the Schedule of Benefits, Physician Services under the Health Insurance Act), all services listed under Laboratory Medicine from L001 to L699 (including L900 codes), L701 to L799 and under the "Laboratory Medicine in Private Office" listings in the Diagnostic and Therapeutic Procedures Section of the Schedule, when performed by a physician for his/her own patients, include the following specific elements: A. Carrying out the laboratory procedure, including collecting specimens where not separately billable, and processing of specimens. B. Interpreting and/or providing the results of the procedure, where not interpreted by a physician under an L800 code, even where the interpreting physician is another physician. C. Discussion with and providing advice and information to the patient or patient's representative(s), whether by telephone or otherwise, on matters related to the service. D. Providing premises, equipment, supplies and personnel for the specific elements and for any aspect(s) of the specific elements, of any service(s) covered by a corresponding L800 code that is (are) performed at the place in which the laboratory procedure is performed. OTHER TERMS AND DEFINITIONS 1. The patient documentation and specimen handling benefit (see code L700 below) is applicable to all insured procedures, except for those listed under anatomical pathology, histology and cytology, the fees for which cover any administrative cost. This benefit is not applicable to referred-in samples, since the collecting laboratory will already have claimed the patient documentation and specimen collection benefit. -
Urinalysis: Sediment Examination, Currently, a Liquid Kidney Biopsy?
Nephrology and Renal Diseases Review Article ISSN: 2399-908X Urinalysis: Sediment examination, currently, a liquid kidney biopsy? Glísia Mendes Tavares Gomes* Laboratório de Diagnóstico, Ensino e Pesquisa-Centro de Saúde Escola Germano Sinval Faria/Escola Nacional de Saúde Pública Sergio Arouca (ENSP/Fiocruz), Rio de Janeiro, Brazil. Abstract The current article aims to assist in understanding the importance of urinalysis, more specifically, urinary sediment examination, in the diagnosis and monitoring of kidney injuries, its particularities and, especially, its most relevant characteristics: sample which is easy to obtain, low execution cost and diagnostic utility. In view of the panorama of the increase in kidney diseases in recent decades, the application of this analytical tool has been of paramount importance, which, when performed well, both in laboratory and clinic, can bring great benefits to patients who use it, being these people in a risk group for chronic kidney diseases or not. The databases used for search were- PubMed, Scielo and Web of Science. Introduction Urine testing is emphasized as an excellent biomarker of kidney disease. We highlight the important contribution of the centrifuged Among the diseases that represent a major public health problem urine test, evaluated by an experienced nephrologist, as a tool in the are the different types of kidney disorders that affect about 850 million diagnosis and management of many conditions that affect the kidneys people around the world [1,2]. It is believed that until 2040, chronic [18-28]. However, studies indicate low sensitivity and high specificity kidney disease (CKD) will be the fifth disease in numbers of death [2,3]. -
A Glossary for Basic Sciences Subjects
Department of Basic Sciences Faculty of Allied Health Sciences University of Peradeniya Sri Lanka June 2020 Dr TN Haththotuwa Terms of Use All rights reserved. No part of this glossary may print, copy, reproduce and redistribute by any means (electronic, photocopying) without obtaining the written permission from the copyright holder (Dr T N Haththotuwa). Any modifications, edition or revision to the original text should carry out only under author’s consent. Failure to comply with the terms of the copyright warning may expose you to legal action for copyright infringement. Published by: Dr TN Haththotuwa Lecturer Department of Basic Sciences Faculty of Allied Health Sciences University of Peradeniya Sri Lanka Published date: 13th June 2020 © Dr TN Haththotuwa Department of Basic Sciences/FAHS/UOP June 2020 2 Preface This document prepared as supportive learning material for first-year Allied health undergraduates of university of Peradeniya, Sri Lanka. This glossary summarizes the list of common scientific terms student should aware of under Human Physiology, Basic Human Anatomy and General Pathology and Basic Biochemistry subjects. The terms are categorize under different topics and course modules for convenience in preparing upcoming lecture topics. These terms will also use in a scientific terms game or Moodle activity in future. Therefore, terms listed without definitions on purpose. At the end of the activity, students will have a complete glossary with definitions. Please note that I have used British English in this document. Therefore, you may notice some spelling differences when you read reference books (E.g. Anaemia, Haemoglobin etc). This glossary may not cover all the scientific terms use under-listed course modules. -
USMLE and COMLEX II
USMLE and COMLEX Review Nephrology Supplement Glomerulonephritis, Acute Tubular Necrosis and Acute Interstitial Nephritis Northwestern Medical Review www.northwesternmedicalreview.com Lansing, Michigan 2014-2015 1. What is Tamm-Horsfall glycoprotein (THP)? Matching (4 – 15): Match the following urinary casts with the descriptions, conditions, or questions _______________________________________ presented hereafter: _______________________________________ A. Bacterial casts _______________________________________ B. Crystal casts _______________________________________ C. Epithelial casts D. Fatty casts _______________________________________ E. Granular casts _______________________________________ F. Hyaline casts G. Pigment casts H. Red blood cell casts 2. What is a urinary cast? I. Waxy casts J. White blood cell casts _______________________________________ _______________________________________ 4. These types of casts are by far the most common _______________________________________ urinary casts. They are composed of solidified Tamm-Horsfall mucoprotein and secreted from _______________________________________ tubular cells under conditions of oliguria, _______________________________________ concentrated urine, and acidic urine. _______________________________________ _______________________________________ _______________________________________ 5. These types of casts are pathognomonic of acute tubular necrosis (ATN) and at times are 3. What are the major types of urinary casts? described as “muddy brown casts”. _______________________________________ -
View and in Accordance with the and RTEC Casts (Rteccs) (2,3)
Original Investigation Diagnostic Utility of Serial Microscopic Examination of the Urinary Sediment in Acute Kidney Injury Vipin Varghese,1,2 Maria Soledad Rivera,1 Ali A. Alalwan,2 Ayman M. Alghamdi,2 Manuel E. Gonzalez,3 and Juan Carlos Q. Velez1,2 Abstract Background Microscopic examination of the urinary sediment (MicrExUrSed) is an established diagnostic tool for AKI. However, single inspection of a urine specimen during AKI is a mere snapshot affected by timing. We hypothesized that longitudinal MicrExUrSed provides information otherwise not identified in a single inspection. Methods MicrExUrSed was undertaken in patients with AKI stage $2 and suspected intrinsic cause of AKI seen for nephrology consultation over a 2-year period. MicrExUrSed was performed on the day of consultation and repeated at a second (2–3 days later) and/or third (4–10 days later) interval. Cast scores were assigned to each specimen. Chawla scores (CS) 3–4 and Perazella scores (PS) 2–4 were categorized as consistent with acute tubular injury (ATI), whereas CS 1–2 and PS 0–1 were categorized as nondiagnostic for ATI (non-ATI). Nonrecovering AKI was defined as a rise in serum creatinine (sCr) $0.1 mg/dl between microscopy intervals. Results At least two consecutive MicrExUrSed were performed in 121 patients (46% women, mean age 61614, mean sCr at consult of 3.361.9 mg/dl). On day 1, a CS and PS consistent with non-ATI was assigned to 64 (53%) and 70 (58%) patients, respectively. After a subsequent MicrExUrSed, CS and PS changed to ATI in 14 (22%) and 16 (23%) patients. -
Laboratory Practicals in Physiology
Laboratory Practicals in Physiology Contents I. BLOOD................................................................................................................................................................4 1. Methods of blood sampling .............................................................................................................................4 2. Anticoagulants .................................................................................................................................................4 3. Blood typing and compatibility tests ...............................................................................................................5 4. Bleeding time ..................................................................................................................................................8 5. Clotting time ....................................................................................................................................................8 6. Prothrombin time (Quick-time) .......................................................................................................................9 7. Partial thromboplastin time (PTT, theoretically only) ................................................................................... 10 8. Thrombin time (theoretically only) ............................................................................................................... 11 9. Hematocrit .................................................................................................................................................... -
HEMATURIA PADA ANAK Pasal 72 Undang-Undang Nomor 19 Tahun 2002 Tentang Hak Cipta
HEMATURIA PADA ANAK Pasal 72 Undang-Undang Nomor 19 Tahun 2002 tentang Hak Cipta: (1) Barangsiapa dengan sengaja dan tanpa hak melakukan perbuatan sebagaimana dimaksud dalam Pasal 2 ayat (1) atau Pasal 49 ayat (1) dan ayat (2) dipidana dengan pidana penjara masing-masing paling singkat 1 (satu) bulan dan/atau denda paling sedikit Rp 1.000.000,00 (satu juta rupiah), atau pidana penjara paling lama 7 (tujuh) tahun dan/atau denda paling banyak Rp 5.000.000.000,00 (lima miliar rupiah). (2) Barangsiapa dengan sengaja menyiarkan, memamerkan, mengedarkan, atau menjual kepada umum suatu Ciptaan atau barang hasil pelanggaran Hak Cipta atau Hak Terkait sebagaimana dimaksud pada ayat (1) dipidana dengan pidana penjara paling lama 5 (lima) tahun dan/atau denda paling banyak Rp 500.000.000,00 (lima ratus juta rupiah). (3) Barangsiapa dengan sengaja dan tanpa hak memperbanyak penggunaan untuk kepentingan komersial suatu Program Komputer dipidana dengan pidana penjara paling lama 5 (lima) tahun dan/atau denda paling banyak Rp 500.000.000,00 (lima ratus juta rupiah). (4) Barangsiapa dengan sengaja melanggar Pasal 17 dipidana dengan pidana penjara paling lama 5 (lima) tahun dan/atau denda paling banyak Rp 1.000.000.000,00 (satu miliar rupiah). (5) Barangsiapa dengan sengaja melanggar Pasal 19, Pasal 20, atau Pasal 49 ayat (3) dipidana dengan pidana penjara paling lama 2 (dua) tahun dan/ atau denda paling banyak Rp 150.000.000,00 (seratus lima puluh juta rupiah). (6) Barangsiapa dengan sengaja dan tanpa hak melanggar Pasal 24 atau Pasal 55 dipidana dengan pidana penjara paling lama 2 (dua) tahun dan/atau denda paling banyak Rp 150.000.000,00 (seratus lima puluh juta rupiah).