Fact Sheet www.gtai.com prices. ply atmarket-competitive sup- materials raw secure and Safe Opportunities prices. competitive and market- levels quality German at well-known guaranteed are puts duction experience. Agreed out- ofpro- decades on back look can who companies established are producers sugar and starch German biorefi in materials raw used commonly most the are sugar and Starch Materials Raw inA Selection the of Players Value Chain Biorefi inGermany Biotechnology Industrial Biorefi Feedstocks nery processes today. The The today. processes nery Hemicellulose Biomass Biomass nery: From Biomass to Chemical Building Blocks From tonery: Chemical Biomass Cellulose Protein nery –AChemical Buildingnery Block Perspective Starch Lignin Oil Pretreatment/ Gasifi Enzymes cation networking. extensive and R&D cooperation Opportunities Association. andLeibniz ciety So- Fraunhofer the include These institutes. non-university renowned of world- anumber also are there well as numerous universities, As tomarket. times quick ensures science and industry between action inter- Close industry. German the forbasis the economic of success the provides R&D environment The Research &Development Intermediate Intermediate Platforms Arabinose Fructose Biobased Sugars Sucrose Glucose Lactose Syngas Starch Xylose Chemocatalysis Biocatalysis partnering. business and R&D cooperation Opportunities legislation. environmental stricter and resources, natural limited pushed by fossil fuel rising prices, “design” of industrial processes sustainable the include drivers Industry industry). the chemical fi in biore- (who companies German drives also of commercialization thegoal with research Innovative Business nery terms primarily come from from come primarily terms nery

Building Blocks Building Chemical Syn Gas Syn C3 C2 C4 C6 C5

Source: ©www.colourbox.com Raw Materials (Starch and Sugar)1

Starch Location Source Biorefinery: Starch and Sugar Producer (1.5 million tons) 01 AVEBE Dallmin potato

BALTIC SEA 02 AVEBE Lüchow potato Kiel BALTIC SEA 03 Cargill Barby wheat NORTH SEA Schleswig-Holstein Mecklenburg- 34 Vorpommern 04 Cargill Krefeld maize Hamburg Schwerin 12

05 Crespel & Deiters Ibbenbühren wheat Bremen 02 01 08 POLAND 06 Emsland Stärke Emlichheim potato Lower Saxony Brandenburg POLAN 09 19 Berlin 07 Emsland Stärke Golßen pea 06 Hanover NETHERLANDSNETHERLANDS 05 11 Magdeburg Potsdam 08 Emsland Stärke Kyritz potato 07 24 15 16 20 North Rhine- 03 09 Emsland Stärke Wietzendorf potato Westphalia10 17 Saxony-Anhalt 04 18 23 25 10 Jäckering Hamm wheat 22 Düsseldorf Dresden 21 32 Erfurt 33 11 Kröner-Stärke Ibbenbühren wheat Saxony Hessen 31 IUM Thuringia 12 Kröner-Stärke Hamburg wheat BELGIUM

Wiesbaden

13 Südstärke Sünching potato Rheinland-Pfalz LUXEM- Mainz 14 Südstärke Schrobenhausen potato BOURG 28 26 CZECH REPUBLIC Saarland 3 27 Sugar Location Capacity Staff Saarbrücken (4.2 million tons) (t/d)2 Stuttgart Bavaria 13 15 Nordzucker Clauen 11,000 145 29 FRANCE 30 Baden-Württemberg 14 16 Nordzucker Klein Wanzleben 15,000 178 Munich 17 Nordzucker Nordstemmen 13,500 184 AUSTRIA 18 Nordzucker Schladen 10,000 153 National Border SWITZERLAND 19 Nordzucker Uelzen 18,000 263 (Federal) State Borders 20 Pfeifer & Langen Appeldorn 7,500 80 Renewable Resources in Germany 21 Pfeifer & Langen Euskirchen 10,000 170 In 2008, around 2 million hectares or almost 17 per- 22 Pfeifer & Langen Jülich 15,000 185 cent of Germany’s arable lands were used for grow- 23 Pfeifer & Langen Könnern 16,500 220 ing renewable resources (starch: 1 million hectares, sugar: 0.36 million hectares). Additional raw material 24 Pfeifer & Langen Lage 7,500 70 for industry and energy comes from Germany’s forests 25 Südzucker Brottewitz 6,000 90 which cover some 11.8 million hectares or one third of 26 Südzucker Ochsenfurt 15,000 200 the country’s total land area. 27 Südzucker Offenau 13,000 150 Starch 28 Südzucker Offstein 15,800 220 In Germany, starch is mainly produced from wheat 29 Südzucker Plattling 15,000 180 (2008: 33%), potatoes (42%), and maize (25%). In 2008, 30 Südzucker Rain 12,000 220 eight companies with 14 production plants (2,300 em- ployees) processed 4.4 million tons of agricultural 31 Südzucker Wabern 7,000 70 commodities into 1.5 million tons of starch, 13 percent 32 Südzucker Warburg 5,000 40 of which was used for industrial processes (e.g., chemistry, 33 Südzucker Zeitz 12,400 160 fermentation). 34 Suiker Unie Anklam 10,500 130 Sugar 1 Other renewable resources, such as wood and wheat, White sugar production (from sugar beet) in 2009/2010 still require additional development efforts such as: - further optimized enzymes was 4.2 million tons (beets contain 18% saccarose – 16 - improved space-time yield percent more than the previous year. Of this sum, only - better pretreatment processes fi ve percent was used for industrial processes (chemistry, - adjustment to existing chemical processes 2 Tons sugar beet per day fermentation). 3 Permanent staff Research & Development Biomass Enz./Pretreat. Sugars Biocatalysis Chemocatalysis Syngas C2 C3 C4 C5 C6 Fraunhofer Institutes Biorefinery: R&D Institutions 01 Applied Polymer Research (IAP)

BALTIC SEA 02 Center for Chemical- Kiel BALTIC SEA Biotechnological NORTH SEA Schleswig-Holstein 10

Mecklenburg- Processes (CBP) Vorpommern Hamburg Schwerin 16 03 Chemical 20 Bremen Technology (ICT) POLAND Lower Saxony Brandenburg POLAN 04 Environmental, Safety 20 Berlin and Energy (UMSICHT) Hanover NETHERLANDSNETHERLANDS 12 08 Magdeburg 01 09 23 Potsdam 05 Interfacial Engineering North Rhine- & Biotechnology (IGB) Westphalia Saxony-Anhalt 04 13 06 Molecular Biology and 22 11 14 Düsseldorf 02 Dresden Applied Ecology (IME) 06 12 15 Erfurt Saxony Hessen 07 Process Engineering IUM Thuringia BELGIUM

and Packaging (IVV) Wiesbaden

Rheinland-Pfalz 08 Wood Research (WKI) LUXEM- Mainz BOURG 13 CZECH REPUBLIC Leibniz Institutes Saarland 17 Saarbrücken 09 Agricultural 21 03 Engineering (ATB) Stuttgart Bavaria 19 FRANCE 05 07 10 Catalysis (LIKAT) Baden-Württemberg Munich 11 Polymer Research (IPF) 18 Universities AUSTRIA

National Border SWITZERLAND 12 Aachen Technical (Federal) State Borders University (RWTH) 13 Dortmund Technical Research & Development Landscape in Germany University (BCI) J In 2008, R&D expenditures rose to an all-time high of 2.64 percent (EUR 66 billion) of national GDP. 14 Dresden Technical University -OECD average is around 2.28 percent (2007) -EU-27 average is around 1.77 percent (2007) 15 Düsseldorf University J 410 universities with world class scientifi c (IMET) research institutions 16 Hamburg-Harburg J 11,000 patents granted by the European Patent Technical University Organization (EPO) in 2009 (No. 1 worldwide) 17 Kaiserslautern Uni. Fraunhofer-Gesellschaft 18 Munich Technical Founded in 1949, the Fraunhofer-Gesellschaft maintains University (TUM) more than 80 research units in Germany, including 59 19 TUM – Science Center Fraunhofer Institutes. The majority of the 17,000 staff are Straubing qualifi ed scientists and engineers who work with an annual Non-university Institutes research budget of EUR 1.6 billion. 20 Institute for Wood Leibniz Association Technology & Wood The Leibniz Association is the umbrella organization Biology (HTB) for 86 institutions conducting research or providing sci- 21 Karlsruhe Institute of entifi c infrastructure with an annual budget of EUR 1.3 Technology (KIT) billion. Members include 7,100 scientists and academics 22 Research Center (total: 16,000 people) working in the social, economics, Jülich (FZJ) spatial and life sciences as well as in mathematics, the 23 Research Institute natural and engineering sciences. BioPos e.V. Biomass Enz./Pretreat. Biocatalysis C2 C3 C4 C5 C6 Sugars Chemocatalysis Syngas Large Companies Companies Active in the Biorefinery Value Chain 01 BASF 02 Bayer Material BALTIC SEA Science Kiel BALTIC SEA 03 Cognis NORTH SEA Schleswig-Holstein 21 27 Mecklenburg- Vorpommern 04 Crop Energies Hamburg Schwerin

26 05 Evonik Bremen

POLAND 06 Lanxess Lower Saxony Brandenburg POLAN

Berlin 07 Merck Hanover NETHERLANDS 15 19 23 NETHERLANDS Magdeburg 08 Süd-Chemie 12 11 Potsdam

28 North Rhine- 09 Westphalia Saxony-Anhalt Wacker 25 05 06 13 16 22 18 SME´s 23 03 02 24 14 20 29 Düsseldorf Dresden

Erfurt 10 AB Enzymes Saxony Hessen IUM Thuringia 11 Amino BELGIUM

Wiesbaden 12 ASA SPEZIAL- Rheinland-Pfalz LUXEM- Mainz ENZYME BOURG 07 10 17 15 CZECH REPUBLIC Saarland 13 Autodisplay Biotech Saarbrücken 01 04 14 Bioreact Stuttgart Bavaria

15 Bioworx FRANCE Baden-Württemberg 08 09 16 bitop Munich 17 BRAIN AUSTRIA 18 c-Lecta National Border SWITZERLAND 19 Cyano Biofuels (Federal) State Borders 20 DIREVO Industrial Pilot and Demonstration Plants Biotechnology Süd-Chemie 21 Enzymicals Süd-Chemie started building Germany’s largest demo 22 evocatal plant (2,000 tons, EUR 28 million) in Straubing for the 23 Phytowelt Green production of bioethanol (from agricultural waste) Technologies based on their sunliquid® process in August 2010. 24 Protagen Uhde Inventa-Fischer 25 Senzyme As a leader in technology and equipment for the produc- 26 SeSaM-Biotech tion of polyester and polyamide polymers, Uhde Inventa- 27 SternEnzym Fischer operates pilot plants in Berlin for its 2-Reactor process. 28 W 42 Industrial Biotechnology Wacker 29 X-Zyme Wacker is reliant on acetic acid and ethylene as building blocks for its vinyl acetate monomers. In October 2009, Wacker began operating a 500 tons per annum pilot plant that produces acetic acid via its ACEO® process in Burghausen, Germany. Industrial Biotechnology Cluster

Industrial Biotechnology Cluster Industrial Biotechnology Cluster (Federal Funding, Number of Partners) 1 BIOCATALYSIS2021, Hamburg BALTIC SEA (EUR 20 million, 67 partners) Kiel BALTIC SEA

The cluster is helping unlock nature’s biodiversity by NORTH SEA Schleswig-Holstein

Mecklenburg- using advanced screening technologies and applying a 1 Vorpommern HaHamburgamburg unique generation of microbial biocatalysts that function Schwerin

in non-conventional conditions (e.g., extreme tempera- Bremen

POLAND tures, pressures, pH values, concentrations of salt Lower Saxony Brandenburg POLAN and solvents). Berlin Hanover

NETHERLANDSNETHERLANDS Magdeburg 2 Cluster Industrial Biotechnology 2021 – CLIB2021, Potsdam

Düsseldorf (EUR 20 million, ›70 partners) North Rhine- Westphalia Saxony-Anhalt The cluster focuses on projects and technologies 2

relevant to the (bio)chemical industry. Special focus is DüsseldorfDüsseldorf Dresden

Erfurt placed on innovative monomers, biocatalytic conver- Saxony Hessen sions, downstream processing, and biotech products for IUM Thuringia BELGIUM a wide range of applications (e.g., adhesives, lubricants, 3 WiesbadenFrankfurtFrankfurt cosmetics, building blocks for pharmaceuticals). Rheinland-Pfalz LUXEM- Mainz BOURG CZECH REPUBLIC 3 Cluster Integrated Bioindustry – CIB, Frankfurt Saarland (EUR 5 million, 59 partners) Saarbrücken Focus on fi ne and speciality chemistry. The signifi cant 4 StuttgartStuttgart Bavaria

advantage of the cluster is that individual components FRANCE (i.e., research, development, production, and fi nancing) Baden-Württemberg 5 MuMunichnich are carefully matched.

AUSTRIA 4 Cluster Biopolymers/Biomaterials, Stuttgart (EUR 20 million, 100 partners) National Border SWITZERLAND (Federal) State Borders

(Federal) State Capital The cluster supports R&D projects that focus on the SWITZERLAND development of innovative biomaterials at competitive prices and make them available on the market by way of The BioIndustry 2021 Competition (BMBF) process optimization along the value creation chain. In order for industrial biotechnology innovations and research results to be transformed more rapidly into 5 BioM WB, Munich marketable products, the BioIndustry 2021 initiative was (EUR 5 million, 74 partners) launched by the German Federal Ministry for Education Network of enterprises and research institutions to and Research (BMBF) in 2007. Federal funding to the develop novel processes and products in the fi eld of value of EUR 60 million is available until 2011. To date, biogenic building blocks and performance proteins. fi ve industry clusters with differing focal points have The network’s stated aim is the proper exploitation been awarded funding through the program. of lignocellulosic material (e.g., straw) using the novel process of sequential enzymatic hydrolysis (SEH) for The Industrial Biotechnolgy Clusters monosaccharides, phenols, and other secondary metabolites which are transformed into basic The clusters have developed networks comprising building blocks like sugar alcohols and acetates. (chemical) industry companies, biotechnology start-ups, science institutes, customer industries, and investors right across Germany. Germany Trade & Invest

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