Progress in Nutrition 2019; Vol. 21, N. 3: 584-590 DOI: 10.23751/pn.v21i3.8385 © Mattioli 1885 Original article Evaluation of antimicrobial activity and activity on the autonomic nervous system of the lavender essential oils from Montenegro Svetlana Perovic1, Snezana Pantovic2, Valentina Scepanovic1, Andrej Perovic1, Vladimir Zivkovic3, Biljana Damjanovic-Vratnica4 1Department of Biology, Faculty of Natural Science and Mathematics, University of Montenegro, Dz. Vasingtona bb, Podgorica 2Faculty of Medicine, University of Montenegro, Krusevac bb, Podgorica - E-mail:
[email protected]; 3Center for Eco- toxicological Research Podgorica, Boulevard Sarla de Gola 2, Podgorica; 4Faculty of Metallurgy and Technology, University of Montenegro, Dz. Vasingtona bb, Podgorica Summary. This study investigates chemical composition and antimicrobial activity of essential oil of Lavandula officinalis from Montenegro, Mediterranean, and effects on autonomic nervous system. The oil was analysed by GC-MS technique in order to determine the majority compounds while dilution method was used to determine minimal inhibitory concentration. The present study assessed autonomic parameters such as blood pressure, heart rate, and skin temperature to determine the arousal level of the autonomic nervous system. In addition, subjects were asked to estimate their mood responses such as feeling pleasant or unpleasant, uncomfortable, sen- suality, relaxation, or refreshing in order to assess subjective behavioural arousal. Chemical analysis by GC-MS identified 31 compounds in lavender oil representing 96.88% of the total oil. Linalool (24.84%), was a major component, together with linalyl acetate (22.39%), 1,8 cineole (18.13%) and camphor (12.88%). The investigat- ed lavender oil consisted mostly of oxygenated monoterpenes (87.95%) and monoterpene hydrocarbons (7%).