Hormone Molecular Biology and Clinical Investigation

HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION

EDITOR-IN-CHIEF Luis M. García-Segura, Madrid, Spain Gérard S. Chetrite, Paris, France Julia M.W. Gee, Cardiff, UK Andrea R. Genazzani, Pisa, Italy ASSOCIATE EDITORS Geoffrey L. Greene, Chicago, USA Jiro Fujimoto, Gifu, Japan Leena Hilakivi-Clarke, Washington, USA Bernd Groner, Frankfurt a.M., Germany Richard Hampl, Praha, Czech Republic Michael Hubalek, Innsbruck, Austria Hirotaka Iwase, Kumamoto, Japan Robert Morfin, Paris, France V. Craig Jordan, Philadelphia, USA Farid Saad, Berlin, Germany Helmut Klocker, Innsbruck, Austria Andrew V. Schally, Miami, USA Junichi Kurebayashi, Okayama, Japan Fernand Labrie, Quebec, Canada JOURNAL MANAGER Van Luu-The, Québec, Canada Steffi Rudloff, Berlin, Germany Carole R. Mendelson, Dallas, USA Alfred O. Mück, Tübingen, Germany CORRESPONDING EDITORS Robert Nicholson, Cardiff, UK Michael N. Alexis, Athens, Greece Anthony W. Norman, Riverside, USA Aria Baniahmad, Jena, Germany Bert W. O’Malley, Houston, USA Miguel Beato, Barcelona, Spain Marie-Edith Rafestin-Oblin, Paris, France Roger Bouillon, Leuven, Belgium Jean-Pierre Raynaud, Paris, France Angela Brodie, Baltimore, USA Xiangyan Ruan, Beijing, China Carlo Campagnoli, Torino, Italy José Russo, Philadelphia, USA Giuseppe Carruba, Palermo, Italy Edwin R. Sanchez, Toledo, USA Shiuan Chen, Duarte, USA Roxana Schillaci, Buenos Aires, Argentina John A. Cidlowski, Research Triangle Park, USA Adolf E. Schindler, Essen, Germany Robert Clarke, Washington DC, USA Gunnar Söderqvist, Stockholm, Sweden Herjan J.T. Coelingh Bennink, Zeist, Netherlands Valerie Speirs, Leeds, UK Giovanna Danza, Firenze, Italy Frank Z. Stanczyk, Los Angeles, USA Philippa D. Darbre, Reading, UK Luboslav Stárka, Praha, Czech Republic Günter Daxenbichler, Innsbruck, Austria Thomas R. Sutter, Memphis, USA Ronald de Kloet, Leiden, Netherlands Abdulmaged Traish, Boston, USA Alejandro F. De Nicola, Buenos Aires, Argentina Jesus A. Tresguerres, Madrid, Spain Jacques Drouin, Montréal, Canada Walter Wahli, Lausanne, Switzerland Maria L. Dufau, Bethesda, USA Ludwig Wildt, Innsbruck, Austria Dean P. Edwards, Houston, USA Kaiping Yang, London, Canada Charles N. Falany, Birmingham, UK Timo Ylikomi, Tampere, Finland Leandro Fernández-Pérez, Las Palmas de Gran Qi Yu, Beijing, China Canaria, Spain Clotilde Ferroud, Paris, France FOUNDING EDITOR Amilcar Flores-Morales, Copenhagen, Denmark Jorge R. Pasqualini, Paris, France ABSTRACTED/INDEXED IN Celdes; CNKI Scholar (China National Knowledge Infrastructure); CNPIEC; EBSCO – Academic Search, TOC Premier; EBSCO Discovery Service; Elsevier – SCOPUS; Google Scholar; J-Gate; Medline/PubMed; Naviga (Softweco); Primo Central (ExLibris); SCImago (SJR); Summon (Serials Solution/ProQuest); TDOne (TDNet); Ulrich's Periodicals Directory/ulrichsweb; WorldCat (OCLC).

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ISSN 1868-1883 ∙ e-ISSN 1868-1891 ∙ CODEN HMBCA4

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RESPONSIBLE EDITOR(S) Dr Gérard S. Chetrite, Assistance Publique - Hôpitaux de Paris, Faculté de Médecine Pierre et Marie Curie, Site Saint-Antoine, INSERM UMR S 938, Centre de Recherche Saint-Antoine, 27 Rue Chaligny, 75571 Paris Cedex 12, France, Email: [email protected] Secretarial Assistant, Sandra MacDonald, Email: [email protected]

JOURNAL MANAGER Steffi Rudloff, De Gruyter, Genthiner Straße 13, 10785 Berlin, Germany, Tel.: +49 (0)30 260 05-245, Fax: +49 (0)30 260 05-325, Email: [email protected]

RESPONSIBLE FOR ADVERTISEMENTS Heiko Schulze, De Gruyter, Genthiner Straße 13, 10785 Berlin, Germany. Tel.: +49 (0)30 260 05-358, Fax: +49 (0)30 260 05-264, Email: [email protected]

TYPESETTING Compuscript Ltd., Shannon, Ireland

PRINTING Franz X. Stückle Druck und Verlag e.K., Ettenheim

Printed in Germany Hormone Molecular Biology and Clinical Investigation 2015 | Volume 23 | Issue 1–3

Contents

Issue No 1 – July Ciara H. O’Flanagan, Laura W. Bowers and Stephen D. Hursting A weighty problem: metabolic perturbations and the Special issue on: Adiposopathy in Cancer obesity-cancer link 47 and (Cardio) Metabolic Diseases: an Endocrine Approach – Part 4 Kiran S. Panickar and Dennis E. Jewell Editors: Gérard S. Chetrite and Bruno Fève The beneficial role of anti-inflammatory dietary ingredients in attenuating markers of chronic low-grade inflammation in aging 59 Editorial Preface Issue No 3 – September - Regular issue Gérard S. Chetrite and Bruno Fève Preface to special issue on Adiposopathy in Cancer and (Cardio)Metabolic Diseases: An Endocrine Approach – Mini-Review Article Part 4 1 Salvatore Chirumbolo

Vitamin D3 in cancer prevention and therapy: the Mini-Review Article nutritional issue 71

Maria Dalamaga and Gerasimos S. Christodoulatos Adiponectin as a biomarker linking obesity and Short Communication adiposopathy to hematologic malignancies 5 Britton Trabert, Roni T. Falk, Frank Z. Stanczyk, Katherine A. McGlynn, Louise A. Brinton and Xia Xu Review Article Reproducibility of an assay to measure serum progesterone metabolites that may be related to breast Lore Lapeire, Hannelore Denys, Véronique Cocquyt and cancer risk using liquid chromatography-tandem mass Olivier De Wever spectrometry 79 When fat becomes an ally of the enemy: adipose tissue as collaborator in human breast cancer 21 Original Article Issue No 2 – August Abdulmaged M. Traish, Karim Sultan Haider, Gheorghe Doros and Ahmad Haider Special issue on: Adiposopathy in Cancer Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in and (Cardio)Metabolic Diseases: an men with benign prostatic hyperplasia 85 Endocrine Approach - Part 4 – Continued Editors: Gérard S. Chetrite and Bruno Fève

Review Articles

Noa Noy, Li Li, Matthew V. Abola and Nathan A. Berger Is retinol binding protein 4 a link between adiposity and cancer? 39