Email [email protected] Description O43854 Fri May 25 10:06:19 BST Date 2012 Unique Job 204e7edbdb55e476 ID

Detailed template

information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

PDB header:blood clotting 1 c1sddB_ Alignment 100.0 44 Chain: B: PDB Molecule:coagulation factor v; PDBTitle: crystal structure of bovine factor vai

PDB header:blood clotting 2 c3cdzB_ Alignment 100.0 45 Chain: B: PDB Molecule:coagulation factor viii chain; PDBTitle: crystal structure of human factor viii

PDB header:blood clotting 3 c2r7eB_ Alignment 100.0 45 Chain: B: PDB Molecule:coagulation factor viii; PDBTitle: crystal structure analysis of coagulation factor viii

PDB header:signaling Chain: A: PDB Molecule:neuropilin-2; 4 c2qqlA_ 100.0 37 Alignment PDBTitle: neuropilin-2 a1a2b1b2 domains in complex with a -blocking2 fab

PDB header:signaling protein Chain: B: PDB Molecule:neuropilin-2; 5 c2qqoB_ 100.0 36 Alignment PDBTitle: crystal structure of the a2b1b2 domains from human neuropilin-2

PDB header:signaling protein Chain: A: PDB Molecule:neuropilin-1; 6 c2qqmA_ 100.0 37 Alignment PDBTitle: crystal structure of the a2b1b2 domains from human neuropilin-1

PDB header:signaling protein Chain: A: PDB Molecule:neuropilin-2; 7 c2qqjA_ 100.0 36 Alignment PDBTitle: crystal structure of the b1b2 domains from human neuropilin-2

PDB header:signaling protein, Chain: A: PDB Molecule:neuropilin-1; 8 c2orxA_ 100.0 37 Alignment PDBTitle: structural basis for ligand binding and heparin mediated activation of2 neuropilin

PDB header:/transferase Chain: A: PDB Molecule:epithelial discoidin domain-containing 9 c4ag4A_ 100.0 23 Alignment 1; PDBTitle: crystal structure of a -fab complex

Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like 10 d1czsa_ 100.0 47 Alignment Family:Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)

PDB header: 11 c2pqsA_ Alignment 100.0 54 Chain: A: PDB Molecule:lactadherin; PDBTitle: crystal structure of the bovine lactadherin c2 domain PDB header:protein binding/cytokine Chain: B: PDB Molecule:neuropilin-1, vascular endothelial 12 c4deqB_ 100.0 32 Alignment growth factor a; PDBTitle: structure of the neuropilin-1/vegf-a complex

Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like 13 d1d7pm_ 100.0 47 Alignment Family:Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)

Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like 14 d1sddb4 100.0 47 Alignment Family:Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)

PDB header:cell adhesion Chain: B: PDB Molecule:discoidin-1 subunit a; 15 c2w95B_ 100.0 20 Alignment PDBTitle: structure of the discoidin i from dictyostelium discoideum2 in complex with galnac at 1.75 angstrom resolution

Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like 16 d1sddb3 100.0 38 Alignment Family:Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)

PDB header:transferase 17 c2z4fA_ Alignment 100.0 32 Chain: A: PDB Molecule:discoidin domain-containing receptor 2; PDBTitle: solution structure of the discoidin domain of ddr2

PDB header:cell adhesion Chain: C: PDB Molecule:discoidin-2; 18 c2vmeC_ 100.0 27 Alignment PDBTitle: structure of the wild-type discoidin ii from dictyostelium2 discoideum

Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like 19 d2qqia2 100.0 37 Alignment Family:Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)

Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like 20 d2qqia1 100.0 40 Alignment Family:Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)

PDB header:sugar binding protein Chain: C: PDB Molecule:fbp32; 21 c3cqoC_ not modelled 99.9 15 Alignment PDBTitle: crystal structure of a f-lectin (fucolectin) from morone saxatilis2 (striped bass) serum PDB header:sugar binding protein Chain: B: PDB Molecule:endo-beta-n-acetylglucosaminidase d; 22 c2xqxB_ not modelled 99.8 18 Alignment PDBTitle: structure of the family 32 carbohydrate-binding module from2 streptococcus pneumoniae endod PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative alpha-l-fucosidase; 23 c3eypB_ not modelled 99.5 11 Alignment PDBTitle: crystal structure of putative alpha-l-fucosidase from bacteroides2 thetaiotaomicron PDB header:blood clotting 24 c3le0A_ Alignment not modelled 99.5 15 Chain: A: PDB Molecule:platelet aggregation factor sm-hpaf; PDBTitle: lectin domain of lectinolysin complexed with glycerol

PDB header:sugar binding protein 25 c2y9iB_ Alignment not modelled 99.5 17 Chain: B: PDB Molecule:carbohydrate binding family 6; PDBTitle: cbm62 in complex with xyloglucan oligosaccharide PDB header:hydrolase Chain: B: PDB Molecule:alpha-n-acetylglucosaminidase family 26 c4a42B_ not modelled 99.4 19 Alignment protein; PDBTitle: cpgh89cbm32-6 produced by clostridium perfringens PDB header:hydrolase Chain: A: PDB Molecule:hyaluronidase; 27 c2j1aA_ not modelled 99.4 20 Alignment PDBTitle: structure of cbm32 from clostridium perfringens beta-n-2 acetylhexosaminidase gh84c in complex with galactose PDB header:sugar-binding protein Chain: A: PDB Molecule:exo-alpha-sialidase; 28 c2v72A_ not modelled 99.4 22 Alignment PDBTitle: the structure of the family 32 cbm from c. perfringens nanj2 in complex with galactose PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylglucosaminidase family 29 c4a44A_ Alignment not modelled 99.3 13 protein; PDBTitle: cpgh89cbm32-5, from clostridium perfringens, in complex with the tn2 antigen PDB header:oxidoreductase 30 c2vz1A_ Alignment not modelled 99.3 15 Chain: A: PDB Molecule:galactose oxidase; PDBTitle: premat-galactose oxidase PDB header:hydrolase Chain: B: PDB Molecule:hyaluronoglucosaminidase; 31 c2w1sB_ Alignment not modelled 99.3 24 PDBTitle: unique ligand binding specificity of a family 322 carbohydrate-binding module from the mu toxin produced by3 clostridium perfringens

PDB header:cell adhesion Chain: A: PDB Molecule:thrombospondin-2; 32 c1yo8A_ 99.3 29 Alignment PDBTitle: structure of the c-terminal domain of human thrombospondin-2

Fold:Galactose-binding domain-like 33 d1k12a_ Alignment not modelled 99.3 12 Superfamily:Galactose-binding domain-like Family:Fucose binding lectin

Fold:Galactose-binding domain-like 34 d1k3ia2 Alignment not modelled 99.2 15 Superfamily:Galactose-binding domain-like Family:Galactose-binding domain PDB header:sugar-binding protein Chain: A: PDB Molecule:yecbm32; 35 c2jdaA_ not modelled 99.2 16 Alignment PDBTitle: structure of a pectin binding carbohydrate binding module2 determined in an monoclinic crystal form. PDB header:carbohydrate-binding protein Chain: B: PDB Molecule:fucolectin-related protein; 36 c2j1sB_ not modelled 99.2 17 Alignment PDBTitle: structure of a streptococcus pneumoniae fucose binding2 module in complex with fucose Fold:Galactose-binding domain-like 37 d1tvga_ Alignment not modelled 99.2 10 Superfamily:Galactose-binding domain-like Family:APC10-like PDB header:transport protein Chain: A: PDB Molecule:intraflagellar transport protein 25; 38 c2yc2A_ not modelled 99.1 18 Alignment PDBTitle: intraflagellar transport complex 25-27 from chlamydomonas PDB header:cell adhesion Chain: A: PDB Molecule:putative chitobiase; 39 c2kd7A_ Alignment not modelled 99.1 13 PDBTitle: solution nmr structure of f5/8 type c-terminal domain of a2 putative chitobiase from bacteroides thetaiotaomicron.3 northeast structural genomics consortium target btr324b

PDB header:protein binding Chain: C: PDB Molecule:low-density lipoprotein receptor; 40 c3m0cC_ 99.1 28 Alignment PDBTitle: the x-ray crystal structure of pcsk9 in complex with the ldl receptor

PDB header:signaling protein Chain: A: PDB Molecule:wnt inhibitory factor 1; 41 c2ygqA_ Alignment 99.1 43 PDBTitle: wif domain- (egf)-like domains 1- 3 of human2 wnt inhibitory factor 1 in complex with3 1,2- dipalmitoylphosphatidylcholine

Fold:Galactose-binding domain-like 42 d1w8oa2 Alignment not modelled 99.1 19 Superfamily:Galactose-binding domain-like Family:Galactose-binding domain PDB header:hydrolase Chain: B: PDB Molecule:alpha-n-acetylglucosaminidase family 43 c4a6oB_ Alignment not modelled 99.1 13 protein; PDBTitle: cpgh89cbm32-4, produced by clostridium perfringens, in2 complex with glcnac-alpha-1,4-galactose PDB header:structural genomics, unknown function Chain: D: PDB Molecule:putative chitobiase; 44 c3hnmD_ Alignment not modelled 99.0 11 PDBTitle: crystal structure of protein bt_411 (putative chitobiase,2 fragment 298-461) from bacteroides thetaiotaomicron,3 northeast structural genomics consortium target btr319d PDB header:blood clotting,hydrolase Chain: L: PDB Molecule:coagulation factor ix, light chain; 45 c1x7aL_ Alignment not modelled 99.0 31 PDBTitle: porcine factor ixa complexed to 1-{3-[amino(imino)2 methyl]phenyl}-n-[4-(1h-benzimidazol-1-yl)-2-fluorophenyl]-3 3- (trifluoromethyl)-1h-pyrazole-5-carboxamide PDB header:hydrolase Chain: B: PDB Molecule:alpha-1,3/4-fucosidase; 46 c3mo4B_ not modelled 99.0 11 Alignment PDBTitle: the crystal structure of an alpha-(1-3,4)-fucosidase from2 bifidobacterium longum subsp. infantis atcc 15697 PDB header:hydrolase Chain: A: PDB Molecule:o-glcnacase nagj; 47 c2v5dA_ Alignment not modelled 99.0 22 PDBTitle: structure of a family 84 glycoside hydrolase and a family2 32 carbohydrate-binding module in tandem from clostridium3 perfringens. PDB header:hydrolase/blood clotting 48 c2f9bL_ Alignment not modelled 99.0 27 Chain: L: PDB Molecule:coagulation factor vii; PDBTitle: discovery of novel heterocyclic factor viia inhibitors PDB header:hydrolase Chain: A: PDB Molecule:bacterial sialidase; 49 c2berA_ Alignment not modelled 99.0 15 PDBTitle: y370g active site mutant of the sialidase from2 micromonospora viridifaciens in complex with beta-neu5ac3 (sialic acid). PDB header:hydrolase/lipid binding protein Chain: L: PDB Molecule:low density lipoprotein receptor variant; 50 c3p5cL_ Alignment not modelled 98.9 22 50 c3p5cL_ not modelled 98.9 22 Alignment PDBTitle: the structure of the ldlr/pcsk9 complex reveals the receptor in an2 extended conformation PDB header:carbohydrate-binding protein Chain: A: PDB Molecule:fucolectin-related protein; 51 c2j22A_ not modelled 98.9 16 Alignment PDBTitle: structure of a streptococcus pneumoniae fucose binding2 module, spx-3 PDB header:transcription Chain: A: PDB Molecule:neurogenic locus notch homolog protein 52 c2vj3A_ not modelled 98.8 46 Alignment 1; PDBTitle: human notch-1 egfs 11-13 Fold:Galactose-binding domain-like 53 d1jhja_ Alignment not modelled 98.8 9 Superfamily:Galactose-binding domain-like Family:APC10-like

PDB header:hydrolase inhibitor/blood clotting 54 c3h5cB_ Alignment not modelled 98.8 23 Chain: B: PDB Molecule:vitamin k-dependent protein z; PDBTitle: x-ray structure of protein z-protein z inhibitor complex PDB header:hydrolase/hydrolase inhibitor Chain: L: PDB Molecule:vitamin k-dependent protein c light chain; 55 c3f6uL_ not modelled 98.8 25 Alignment PDBTitle: crystal structure of human activated protein c (apc) complexed with2 ppack PDB header:hydrolase/hydrolase inhibitor Chain: L: PDB Molecule:des-gla factor viia (light chain); 56 c1dvaL_ not modelled 98.8 28 Alignment PDBTitle: crystal structure of the complex between the peptide exosite inhibitor2 e-76 and coagulation factor viia PDB header:cell adhesion Chain: A: PDB Molecule:neurexin-1-alpha; 57 c3poyA_ not modelled 98.8 13 Alignment PDBTitle: crystal structure of the alpha-neurexin-1 ectodomain, lns 2-6 PDB header:cell adhesion Chain: B: PDB Molecule:neurexin-1-alpha; 58 c3qcwB_ not modelled 98.8 14 Alignment PDBTitle: structure of neurexin 1 alpha (domains lns1-lns6), no splice inserts PDB header:cell adhesion 59 c3k6sB_ Alignment not modelled 98.6 29 Chain: B: PDB Molecule:integrin beta-2; PDBTitle: structure of integrin alphaxbeta2 ectodomain PDB header:hydrolase/lipid binding protein Chain: L: PDB Molecule:low density lipoprotein receptor variant; 60 c3p5bL_ not modelled 98.6 19 Alignment PDBTitle: the structure of the ldlr/pcsk9 complex reveals the receptor in an2 extended conformation PDB header: Chain: A: PDB Molecule:fibrillin-1; 61 c2w86A_ not modelled 98.5 17 Alignment PDBTitle: crystal structure of fibrillin-1 domains cbegf9hyb2cbegf10,2 calcium saturated form PDB header:immune system, hydrolase Chain: A: PDB Molecule:urokinase-type plasminogen activator; 62 c2fd6A_ Alignment not modelled 98.5 18 PDBTitle: structure of human urokinase plasminogen activator in complex with2 and an anti-upar antibody at 1.9 a PDB header:plasminogen activation Chain: A: PDB Molecule:t-plasminogen activator f1-g; 63 c1tpgA_ Alignment not modelled 98.5 38 PDBTitle: f1-g module pair residues 1-91 (c83s) of tissue-type2 plasminogen activator (t-pa) (nmr, 298k, ph2.95,3 representative structure) PDB header:immune system Chain: A: PDB Molecule:egf-like module containing mucin-like 64 c2bo2A_ Alignment not modelled 98.5 15 hormone PDBTitle: egf domains 1,2,5 of human , a 7-tm immune system2 molecule, in complex with calcium. PDB header:immune system Chain: C: PDB Molecule:major merozoite surface protein; 65 c1ob1C_ not modelled 98.4 20 Alignment PDBTitle: crystal structure of a fab complex whith plasmodium2 falciparum msp1-19 PDB header:cell adhesion 66 c1n1iC_ Alignment not modelled 98.4 18 Chain: C: PDB Molecule:merozoite surface protein-1; PDBTitle: the structure of msp-1(19) from plasmodium knowlesi

PDB header:lipid transport 67 c1n7dA_ Alignment not modelled 98.4 17 Chain: A: PDB Molecule:low-density lipoprotein receptor; PDBTitle: extracellular domain of the ldl receptor

Fold:Knottins (small inhibitors, toxins, lectins) 68 d1tpga1 Alignment not modelled 98.4 40 Superfamily:EGF/Laminin Family:EGF-type module PDB header:matrix protein Chain: A: PDB Molecule:fibrillin; 69 c1emoA_ not modelled 98.3 22 Alignment PDBTitle: nmr study of a pair of fibrillin ca2+ binding epidermal2 growth factor-like domains, 22 structures PDB header:matrix protein Chain: C: PDB Molecule:fibrillin-1; 70 c1uzjC_ not modelled 98.3 17 Alignment PDBTitle: integrin binding cbegf22-tb4-cbegf33 fragment of human2 fibrillin-1, holo form. Fold:Knottins (small inhibitors, toxins, lectins) 71 d2vj3a3 Alignment not modelled 98.3 46 Superfamily:EGF/Laminin Family:EGF-type module PDB header:receptor Chain: A: PDB Molecule:neurogenic locus notch homolog protein 72 c2rqzA_ Alignment not modelled 98.2 37 1; PDBTitle: structure of sugar modified epidermal growth factor-like repeat 12 of2 mouse notch-1 receptor Fold:Knottins (small inhibitors, toxins, lectins) 73 d2vj3a2 Alignment not modelled 98.2 37 Superfamily:EGF/Laminin Family:EGF-type module PDB header:hydrolase/hydrolase inhibitor Chain: K: PDB Molecule:; 74 c1dx5K_ not modelled 98.2 20 Alignment PDBTitle: crystal structure of the thrombin-thrombomodulin complex Fold:Knottins (small inhibitors, toxins, lectins) 75 d1edmb_ Alignment not modelled 98.2 49 Superfamily:EGF/Laminin Family:EGF-type module PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-2; 76 c2p28B_ not modelled 98.2 21 Alignment PDBTitle: structure of the phe2 and phe3 fragments of the integrin beta2 subunit Fold:Knottins (small inhibitors, toxins, lectins) 77 d2c4fl1 Alignment not modelled 98.2 43 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 78 d1f7ea_ Alignment not modelled 98.2 28 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 79 d1dval1 Alignment not modelled 98.2 39 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 80 d1pfxl1 Alignment not modelled 98.2 51 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 81 d1g1sa2 Alignment not modelled 98.2 33 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 82 d1danl1 Alignment not modelled 98.1 37 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 83 d1ccfa_ Alignment not modelled 98.1 43 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 84 d1g1ta2 Alignment not modelled 98.1 26 Superfamily:EGF/Laminin Family:EGF-type module PDB header:structural protein Chain: A: PDB Molecule:fibrillin 1; 85 c1lmjA_ not modelled 98.1 26 Alignment PDBTitle: nmr study of the fibrillin-1 cbegf12-13 pair of ca2+2 binding epidermal growth factor-like domains Fold:Knottins (small inhibitors, toxins, lectins) 86 d1xkba1 Alignment not modelled 98.1 41 Superfamily:EGF/Laminin Family:EGF-type module

PDB header:glycoprotein 87 c1wheA_ Alignment not modelled 98.1 26 Chain: A: PDB Molecule:coagulation factor x; PDBTitle: coagulation factor, nmr, 20 structures

Fold:Knottins (small inhibitors, toxins, lectins) 88 d2vj3a1 Alignment not modelled 98.0 51 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 89 d1cvua2 Alignment not modelled 97.9 34 Superfamily:EGF/Laminin Family:EGF-type module PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; 90 c1u8cB_ not modelled 97.9 20 Alignment PDBTitle: a novel adaptation of the integrin psi domain revealed from its2 crystal structure PDB header:hydrolase Chain: A: PDB Molecule:hyaluronidase-1; 91 c2pe4A_ not modelled 97.9 18 Alignment PDBTitle: structure of human hyaluronidase 1, a hyaluronan hydrolyzing enzyme2 involved in tumor growth and PDB header:membrane protein 92 c1dqbA_ Alignment not modelled 97.9 25 Chain: A: PDB Molecule:thrombomodulin; PDBTitle: nmr structure of thrombomodulin egf(4-5)

Fold:Knottins (small inhibitors, toxins, lectins) 93 d3egfa_ Alignment not modelled 97.9 27 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 94 d1p9ja_ Alignment not modelled 97.8 22 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 95 d1q4ga2 Alignment not modelled 97.8 32 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 96 d1haea_ Alignment not modelled 97.8 26 Superfamily:EGF/Laminin Family:EGF-type module PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-l-fucosidase; 97 c3gzaB_ Alignment not modelled 97.8 21 PDBTitle: crystal structure of putative alpha-l-fucosidase (np_812709.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.60 a resolution Fold:Knottins (small inhibitors, toxins, lectins) 98 d1jl9a_ Alignment not modelled 97.8 22 Superfamily:EGF/Laminin Family:EGF-type module

Fold:Knottins (small inhibitors, toxins, lectins) 99 d1gk5a_ Alignment not modelled 97.8 27 Superfamily:EGF/Laminin Family:EGF-type module PDB header:hormone/signaling protein Chain: D: PDB Molecule:protein spitz; 100 c3c9aD_ not modelled 97.8 28 Alignment PDBTitle: high resolution crystal structure of argos bound to the egf2 domain of spitz PDB header:cell adhesion Chain: B: PDB Molecule:ookinete surface protein pvs25; 101 c1z1yB_ not modelled 97.8 15 Alignment PDBTitle: crystal structure of methylated pvs25, an ookinete protein2 from plasmodium vivax PDB header:structural protein 102 c2y38A_ Alignment not modelled 97.6 16 Chain: A: PDB Molecule:laminin subunit alpha-5; PDBTitle: laminin alpha5 chain n-terminal fragment Fold:Knottins (small inhibitors, toxins, lectins) 103 d1nqlb_ Alignment not modelled 97.6 22 Superfamily:EGF/Laminin Family:EGF-type module PDB header:membrane protein Chain: A: PDB Molecule:adam 22; 104 c3g5cA_ not modelled 97.6 20 Alignment PDBTitle: structural and biochemical studies on the ectodomain of human adam22 PDB header:transferase, signaling protein 105 c3fl7A_ Alignment not modelled 97.5 14 Chain: A: PDB Molecule:ephrin receptor; PDBTitle: crystal structure of the human ephrin a2 ectodomain PDB header:glycoprotein Chain: A: PDB Molecule:laminin; 106 c1kloA_ Alignment not modelled 97.5 18 PDBTitle: crystal structure of three consecutive laminin-type2 epidermal growth factor-like (le) modules of laminin3 gamma1 chain harboring the nidogen binding site Fold:Knottins (small inhibitors, toxins, lectins) 107 d1lmja1 Alignment not modelled 97.5 31 Superfamily:EGF/Laminin Family:EGF-type module PDB header:signaling protein Chain: A: PDB Molecule:wnt inhibitory factor 1; 108 c2ygpA_ Alignment not modelled 97.4 35 PDBTitle: wif domain-egf-like domain 1 met77trp of human wnt inhibitory factor2 1 in complex with 1,2- dipalmitoylphosphatidylcholine PDB header:cell cycle,signaling protein Chain: B: PDB Molecule:neurogenic locus notch homolog protein 109 c2oo4B_ Alignment not modelled 97.4 20 2; PDBTitle: structure of lnr-hd (negative regulatory region) from human notch 2 PDB header:cell adhesion protein Chain: A: PDB Molecule:human e-; 110 c1eslA_ not modelled 97.4 26 Alignment PDBTitle: insight into e-selectin(slash)ligand interaction from the2 crystal structure and mutagenesis of the lec(slash)egf3 domains PDB header:protein binding 111 c3v64C_ Alignment not modelled 97.4 12 Chain: C: PDB Molecule:agrin; PDBTitle: crystal structure of agrin and lrp4

PDB header:cell cycle 112 c1gqpB_ Alignment not modelled 97.3 10 Chain: B: PDB Molecule:doc1/apc10; PDBTitle: apc10/doc1 subunit of s. cerevisiae PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylglucosaminidase; 113 c2vcbA_ not modelled 97.3 23 Alignment PDBTitle: family 89 glycoside hydrolase from clostridium perfringens2 in complex with pugnac PDB header:cell adhesion Chain: C: PDB Molecule:cartilage oligomeric matrix protein; 114 c3fbyC_ not modelled 97.2 14 Alignment PDBTitle: the crystal structure of the signature domain of cartilage oligomeric2 matrix protein. PDB header:cell adhesion 115 c3cfwA_ Alignment not modelled 97.1 29 Chain: A: PDB Molecule:l-selectin; PDBTitle: l-selectin lectin and egf domains PDB header:cell adhesion Chain: A: PDB Molecule:integrin beta-2; 116 c2p26A_ not modelled 97.1 29 Alignment PDBTitle: structure of the phe2 and phe3 fragments of the integrin beta2 subunit PDB header:protein binding Chain: B: PDB Molecule:low-density lipoprotein receptor-related 117 c3v65B_ not modelled 97.0 13 Alignment protein 4; PDBTitle: crystal structure of agrin and lrp4 complex PDB header:protein-binding 118 c2vj2A_ Alignment not modelled 96.9 19 Chain: A: PDB Molecule:jagged-1; PDBTitle: human jagged-1, domains dsl and egfs1-3 PDB header:signaling protein Chain: A: PDB Molecule:amphiregulin; 119 c2rnlA_ not modelled 96.9 23 Alignment PDBTitle: solution structure of the egf-like domain from human2 amphiregulin PDB header:blood clotting Chain: A: PDB Molecule:vitamin k-dependent protein s; 120 c1z6cA_ not modelled 96.8 20 Alignment PDBTitle: solution structure of an egf pair (egf34) from vitamin k-2 dependent protein s