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Retinitis Pigmentosa Stem-Cell Trial Enters New Phase
In this Issue Story Pg Retinitis pigmentosa stem-cell trial 1 enters new phase Message from the chair 3 Changing lives one cataract at a time 4 Welcome new faculty 4 Spring 2019 Better vision for special needs patients 5 Supporting a brighter world for children 6 Thank you to our donors 6 Dedicated to helping others see 7 RESEARCH UPDATE Retinitis pigmentosa stem-cell trial enters new phase The promising use of progenitor cells to treat retinitis pigmentosa, which was developed at UCI Health Gavin Herbert Eye Institute (GHEI), has entered a new phase to evaluate the effectiveness of the treatment and its safety. More than 80 volunteers who have retinitis pigmentosa, a vision-robbing condition for which there is no effective treatment, have received injections in one eye for the Phase 2b trial, said GHEI researcher Dr. Henry Klassen, principal investigator and director of the stem cell and retinal regeneration program. Only one eye was given an injection of progenitor cells, which are partly developed stem cells, so that researchers can evaluate how much the person’s vision improved in the treated eye. They’ll start unmasking the results in June, 2019. Dr. Henry Klassen continued on page 2 Trial enters new phase, continued from page 1 The Phase 2b trial also differs in terms of whether and Klassen said the next trial will involve a changed how patients were treated. During the initial trial, which scenario. The U.S. Food and Drug Administration wants emphasized safety, all patients received one of four researchers to use a commercially prepared product, just different doses of progenitor cells, which were injected as the general population would receive. -
World Report on Vision
World report on vision A World report on vision © World Health Organization 2019 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO; https:// creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization, products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or equivalent Creative Commons licence. If you create a translation of this work, you should add the following disclaimer along with the suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not responsible for the content or accuracy of this translation. The original English edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization. Suggested citation. World report on vision. Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data. CIP data are available at http://apps.who.int/ iris. Sales, rights and licensing. To purchase WHO publications, see http://apps.who.int/ bookorders. To submit requests for commercial use and queries on rights and licensing, see http://www.who.int/about/licensing. -
1 Professor José-Alain SAHEL Centre Hospitalier
Professor José-Alain SAHEL Centre Hospitalier National d’Ophtalmologie des Quinze-Vingts Date of birth: 1955/07/12 Tlemcen (Algeria) 28, rue de Charenton, 75557 Paris Cedex 12. FRANCE [email protected]. [email protected] Phone: +33 (0)1 53 46 25 04 Fax: +33 (0)1 53 46 25 05 Medical license: 75/67740 EDUCATION 1979-1980 Ophthalmology residency at A. Rothschild Foundation, Paris 1980-1984 Residency Louis Pasteur University Hospital (Neurology, Neurosurgery, Ophthalmology), Strasbourg 1980 Medical Degree-Paris University Medical School (Jury congratulations, Thesis medal) 1981 Oto-Neuro-Ophthalmologic Radiology University Degree 1984 Ophthalmology Degree – National Board Post-doctoral studies 1984-1988 Clinical fellow (Assistant), Department of Ophthalmology, Louis Pasteur University Hospital, Strasbourg 1984-1988 Chef de Clinique des Universités- - Louis Pasteur University Medical School, Strasbourg 1986-1987 Research Fellow in Ophthalmology (Pr D.M Albert)- Massachusetts Eye and Ear Infirmary - Harvard Medical School, Boston, USA Visiting Scholar in Biology (Pr J.E. Dowling) - The Harvard Biological Laboratories - Department of Cellular and Developmental Biology – Harvard University, Cambridge, Massachusetts, USA UNIVERSITY POSITIONS 1987-1992 Visiting Lecturer in Ophthalmology - Department of Ophthalmology - Harvard Medical School, Boston, Massachusetts, USA 1988-2002 University Professor of Ophthalmology – Strasbourg University (1st class since 1999) 1993-1995 Visiting Professor - Department of Ophthalmology and Visual Sciences, -
SERI Annual Report – FY2019-2020
SIGHT MATTERS Annual Report FY2019/2020 CONTENT PAGE 2 ABOUT US 3 CHAIRMAN’S MESSAGE 4 EXECUTIVE DIRECTOR’S MESSAGE 5 INSTITUTIONAL REPORT 12 OUR PEOPLE SERI’S BOARD OF DIRECTORS SERI’S DIRECTORS / STRATEGIC PLANNING COMMITTEE SERI’S RESEARCH HEADS SNEC’s RESEARCH & INNOVATIVE COMMITTEE TEACHING & TRAINING OUR COLLABORATIONS 21 EVENTS INTERNATIONAL & LOCAL ACTIVITIES GALA FUND-RAISING DINNER, THE EYE BALL 2019 26 ACHIEVEMENTS OUR AWARDS OUR GRANTS OUR PUBLICATIONS 68 FINANCIAL REPORT 108 APPENDIX ABOUT US Established in 1997, the Singapore Eye Research Institute (SERI) is Singapore’s national research institute for ophthalmic and vision research. It is the research arm of the Singapore National Eye Centre, and affiliated to the National University of Singapore and the Duke-NUS Medical School. In two decades, SERI has grown from a team of 5 to over 235 staff, encompassing clinician scientists, scientists, fellows, students, support staff, as well as more than 229 distinguished adjunct faculty members to become the largest eye research institute in the Asia-Pacific region. As of Mar 2020, SERI has published 4,003 peer-reviewed papers supported by S$328 million in competitive research grants. SERI has trained more than 204 current and past graduate students; and has been conferred over 619 national & international awards and 135 patents. SERI further undertakes eye research in collaboration with local & international ophthalmic medical centres and research institutions, which has ensured a high level of research competency & skills transfer. Notably, SERI’s research has translated to actual patient success stories & significant improvements in eye care delivery. Today, SERI is recognized as a pioneering center for high quality eye research in Asia, with breakthrough discoveries that has translated to significant paradigm shift in eye care delivery. -
CURRICULUM VITAE Hendrik Peter Nicolas Scholl
CURRICULUM VITAE Hendrik Peter Nicolas Scholl October 1, 2013 DEMOGRAPHIC INFORMATION Current Title and Appointments Dr. Frieda Derdeyn Bambas Professor of Ophthalmology The Wilmer Eye Institute, Johns Hopkins University Medical School Director, Retinal Degeneration Clinic (Retina Division, Wilmer Eye Institute) Director, Visual Neurophysiology Service (Johns Hopkins Hospital) Co-director of the Johns Hopkins Center for STem Cells and Ophthalmic Regenerative Medicine (STORM) Personal Data Wilmer Eye Institute Johns Hopkins University 748 Maumenee Building 1800 Orleans Street Baltimore, MD 21287-9277 phone: (443) 287 5495 e-mail: [email protected] Education and Training (in chronological order) Doctoral/graduate 1989 – 1997 Medical Doctor (Dr. med.), Medical Faculty, University of Tübingen, Germany Thesis: Motion thresholds of colored stimuli of different luminance contrasts are increased in ocular hypertension and early primary-open-angle-glaucoma 1989 – 1997 Magister Artium (Master of Arts), University of Tübingen (Faculty of Philosophy) Thesis: Remembrance and authenticity. Husserl‘s, Bergson‘s and Heidegger‘s philosophy of time with comments on Proust 1/1/1994 – 5/31/1994 Medical School, Brown University, Providence, Rhode Island, USA Clinical Clerkship: Medicine; Electives: (1) Ophthalmology, (2) Emergency Medicine Postdoctoral 1997 – 2001 Resident in Ophthalmology and Post-Doc Researcher, University Eye Hospital Tübingen Training in anterior and posterior segment clinical ophthalmology Specialized Clinic “Inherited Retinal Dystrophies”