THE NINETY-SEVENTH PRESENTATION of the WILLARD GIBBS MEDAL (Founded by William A. Converse) to PROFESSOR CAROLYN R
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http://chicagoacs.org MAY • 2008 THE NINETY-SEVENTH PRESENTATION OF THE WILLARD GIBBS MEDAL (Founded by William A. Converse) to PROFESSOR CAROLYN R. BERTOZZI sponsored by the CHICAGO SECTION AMERICAN CHEMICAL SOCIETY FRIDAY, MAY 9, 2008 Carriage Greens Country Club DINNER 7:00 P.M. function and medical diagnostics. 8700 Carriage Greens Drive Darien, IL 60561 Dinner reservations are required. To Acceptance of the Award 630-985-3400 reserve your tickets, please call the Chicago Section office at 847-647-8405 From Chicago: or register at http://ChicagoACS.org Take the Stevenson Expressway (I-55) by Tuesday, May 6 and pay $45 at the west past the Tri-State Tollway (I-294) door, or fill out the reservation form on and exit north on Cass Avenue. Turn page 7 and mail it with your payment of left on the North Frontage Road. Follow $45 by Wednesday, April 30 to the the frontage road alongside I-55 to Car- address given on the form. If you have riage Greens Drive. Turn right on Car- not paid dues to the Local Chicago riage Greens Drive and proceed to the Section ($15 per year), the price is $47. country club. Note: Professors must make reserva- tions for their students ($22.50). From Milwaukee or the north: (continued on page 2) Take I-94 East to I-294 South. Stay on I-294 to I-55 West. Go west to Cass AWARD CEREMONY 8:30 PM Avenue. Exit northbound on Cass and Dr. Carolyn R. Bertozzi turn left on the North Frontage Road. The Willard Gibbs Medal T.Z. and Irmgard Chu Distinguished Follow the frontage road alongside I-55 Professor of Chemistry and Professor to Carriage Greens Drive. Turn right on Dr. David S. Crumrine, Chair of Molecular and Cell Biology, Universi- Carriage Greens Drive and proceed to Chicago Section, ACS ty of California, Berkeley the country club. Introduction of the Medalist ACCEPTANCE ADDRESS From Northern Indiana or the south: Take I-294 North to I-55 West. Head Presentation of the Medal and Citation “Chemistry in Living Systems: west to Cass Avenue and follow the Shedding Light on Glycans” directions above. The Citation: Abstract: A majority of cell surface Parking: Free For profiling changes in cell surface and secreted proteins are posttransla- glycosylation associated with cancer, tionally modified by the addition of gly- RECEPTION 6:00-7:00 P.M. inflammation and bacterial infection; for cans. These complex structures can Hors-d’oeuvres exploiting this information for develop- provide information regarding the state Champagne Punch and Non-alcoholic ment of diagnostic and therapeutic of health of cells or organisms. Indeed, Punch approaches; and for developing changes in the structures of protein- nanoscale technologies for probing cell (continued on page 2) 5/08 2 (continued from page 1) (continued from page 1, column 2) NOTICE TO ILLINOIS and cell surface-associated glycans are TEACHERS Tables of 10 may be reserved. If you a hallmark of many cancers, chronically request seating for a group, please inflamed tissues, and microbial infec- The Chicago Section ACS is an include a list of names of the people in tions. The ability to probe glycosylation ISBE provider for professional your group and their meal choices. in living systems may therefore reveal development units for Illinois teach- Tickets and nametags will be available new biomarkers of disease and provide ers. Teachers who register for this at the door. No refunds will be made new avenues for diagnostic imaging. month's meeting will have the after noon, on Tuesday, May 6. We are developing chemical technolo- opportunity to earn up to 3 CPDU's. gies for visualizing glycans in living sys- THE MENU: Caesar Salad; a choice of tems. As products of secondary Seared Medallions of Beef with Bur- metabolism, glycans are constructed REGISTER ONLINE for gundy Reduction Sauce, Broiled from simple monosaccharide precur- Chicago Section Atlantic Salmon with Bearnaise Sauce, sors. We exploit these metabolic path- or Pasta Primavera; Twice Baked ways to incorporate bioorthogonal monthly meetings www.ChicagoACS.org Potato and Whole Baby Green Beans; chemical reporters into glycans. The Peach Cobbler; Wine chemical reporters comprise small func- tional groups, such as the azide, that can be detected by covalent reaction with highly selective probes. New chemical reactions have been devel- oped for this purpose, such as the Staudinger ligation with phosphines and strain-promoted [3+2] cycloaddition with functionalized cyclooctynes. Applica- tions of the technique to the identifica- tion of cancer-associated glycan biomarkers and noninvasive imaging are currently being pursued. THE MEDALIST Carolyn Bertozzi is the T.Z. and Irm- gard Chu Distinguished Professor of Chemistry and Professor of Molecular and Cell Biology at UC Berkeley, an Investigator of the Howard Hughes Medical Institute, and Director of the Molecular Foundry, a nanoscience insti- tute at the Lawrence Berkeley National Laboratory. She completed her under- SMALL BUSINESS IN THIS ISSUE graduate degree in Chemistry from Har- INNOVATION RESEARCH 1 — Gibbs Banquet and vard University in 1988 and her Ph.D. in PROGRAM Chemistry from UC Berkeley in 1993. Meeting After completing postdoctoral work at Are you starting a new science busi- 2 — Notice to Illinois Teach- UCSF in the field of cellular immunolo- ness? Finding funding for your innova- gy, she joined the UC Berkeley faculty tive venture can be challenging. SBIR ers in 1996. or Small Business Innovation Research 2 — Small Business Innova- Prof. Bertozzi’s research interests is a program that will help jump start tion Research span the disciplines of chemistry and your new science business. iBIO, the biology with an emphasis on studies of Illinois Biotechnology Organization, pro- 3 — ChemShorts for Kids: cell surface glycosylation pertinent to vides workshops periodically through- Periodic Tables disease states. Her lab focuses on pro- out the year. For more information 3 — Important Notice filing changes in cell surface glycosyla- about the next SBIR seminar contact tion associated with cancer, inflamma- Ann Reed at iBIO Institute 3 — Join Us at the Fair! tion and bacterial infection, and exploit- ([email protected]) or Lisa 4 — LAN ing this information for development of Kurek of Biotechnology Business Con- 5 — Willard Gibbs Award diagnostic and therapeutic approaches. sultants ([email protected]). In addition, her group develops The next iBIO Institute SBIR workshop 6 — Another Scientist in the nanoscience-based technologies for will be held in Chicago this April. House probing cell function and for medical National conferences coming up are on 6 — Science Debate 2008 diagnostics. July 22-23 in Atlanta, GA and Nov 12- 14 in Hartford, CT (http://www.sbir. 6 — Send in Your Email gov/events/). Address! For more details please read the sum- 7 — Gibbs Dinner Coupon mary of the January iBIO workshop, http://www.ibio.org/members/ 7 — Ad Index only/atibio/2008-01/sbirwork 8 — Calendar shop.html 5/08 3 Groups of Elements Periodic Table -- May, 2008 Vol. 95, No. 5. Published (http://chemistry.about.com/library/ by the Chicago Section of The Ameri- weekly/blgroups.htm). If you click a link can Chemical Society, Editorial Staff: on this table you get information about Cherlyn Bradley, Editor; Fran Kravitz, The Elementary Education Committee the group to which the element belongs. Associate Editor; Fadwa Al-Taher and of the Chicago Section ACS presents Richard Treptow, Proofreaders; Frank this column. They hope that it will reach Fireworks Periodic Table -- Jarzembowski, Publications Business young children and help increase their (http://chemistry.about.com/library/w Manager. Address: 7173 North science literacy. Please cut it out and eekly/blfireworks.htm). Clicking an Austin, Niles, Illinois 60714; 847/647- pass it on to your children, grandchil- element will tell you how it is used in 8405. Subscription rates: $15 per dren, or elementary school teachers. It fireworks and other pyrotechnic devices. year. Frequency: monthly-September is hoped that teachers will incorporate through June. some of the projects in this column into Periodic Table sorted by Abundance – their lesson plans. In the June 1998 column of “ChemShorts for Kids” we gave the ref- Panoply of Periodic Tables erence to our article on an activity using the periodic table sorted by abundance Kids, what is the most popular chart on the Earth’s surface: http://member- used by chemists? Elements are the ship.acs.org/c/chicago/ChmShort/CS IMPORTANT NOTICE building blocks of all matter, and cur- 98.html#6.98 The Chemical Bulletin is changing! rently there are about 117 different and unique atoms comprising the elements. Edited by K. A. Carrado, Argonne Starting September 2008, primary There are many ways to arrange the National Laboratory distribution of The Chemical Bul- chemical elements into a chart. Dmitri letin will be an electronic version. Mendeleev arranged rows and columns All past “ChemShorts” are at We will send you the link to each so that elements were grouped accord- http://membership.acs.org/C/Chica- issue by email. You will have the ing to their recurring (periodic) proper- go/ChmShort/kidindex.html. option to not receive the email notifi- ties. Mendeleev's table forms the basis cation, and you will still be able to for the modern periodic table of the ele- reach each issue through the Sec- ments, which lists the elements in order tion web page. You also will still of increasing atomic number while have the option of receiving a paper grouping them according to periodic copy of The Chemical Bulletin for a properties. But there isn't just one mod- small additional fee. More details will ern periodic table of the elements. be given in The Chemical Bulletin Unless you want a table that is impossi- and also at the Chicago Section web ble to read, there is a limit to the num- page: www.chicagoacs.org.