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Summer ROCKEFELLER 2019 INSTITUTE at WEST VIRGINIA UNIVERSITY TABLE OF 10 Department of Neuroscience CONTENTS 12 Department of Neurology 2 Message from the Executive Chair 14 Department of Neurosurgery 4 WVU Medicine At-Large 16 Department of Behavioral Medicine and Psychiatry 5 Rockefeller Neuroscience Institute Structure 18 Human Performance Center 6 RNI by the Numbers 20 Research and Innovation Ecosystem The Rockefeller Neuroscience Institute Multidisciplinary Team 22 Milestones celebrated the opening of its new Innovation 8 Center on May 15, 2019. L-R: Albert Wright, Jr., PharmD, MHA; Ali Rezai, MD; Sharon Percy Rockefeller; Sen. John D. “Jay” Rockefeller IV; Charles Rockefeller; Clay Marsh, MD; Laurie Erickson; Gordon Gee, JD, EdD. Dear Friends, The Rockefeller Neuroscience Institute (RNI) is has attracted brilliant minds to Morgantown with unlocking mysteries of maladies that can strike at the opportunity to engage in purpose-driven work the very heart of our humanity with a sense of urgency. Dr. and affect us to our souls. Rezai and the entire RNI team My sisters and I felt helpless are making groundbreaking as the ravages of Alzheimer’s progress with first-in-the-world stripped our mother, Blanchette treatments and unprecedented Hooker Rockefeller, of her partnerships. ability to appreciate music, art, The global impact of new and loved ones. The disease treatment options for devastating stripped her of her dignity. It neurological disorders and extinguished the light from her the RNI’s expanded focus on blue eyes. addiction research can be Heart-broken, Hope, Alida, transformative and life-giving. Sandra, and I knew that we must My vision was that advances do everything in our power to Then-Governor John D. Rockefeller IV in neuroscience would one day and his mother, Blanchette Rockefeller. end that kind of suffering. And, I (Photo: R. Corkery/NY Daily News Archive via Getty Images.) bring hope to families like mine. knew that West Virginia, a place The RNI is taking us there. where people are driven by passion and purpose, was the right place to fulfill that Be well, mission. Two decades ago, my sisters and I helped to “The Boundless Brain” mural, a found an institute that would begin that journey. depiction of half a million neurons in the human brain, adorns the lobby of the Today, we celebrate the promise that is being Rockefeller Neuroscience Institute Innovation Center. realized. The Rockefeller Neuroscience Institute Jay Rockefeller The mural was created by Greg Dunn and Brian Edwards. 1 “We care deeply about our patients and families in West MESSAGE FROM THE Virginia, across the country, and around the world; our boldest EXECUTIVE CHAIR aspiration is to make their lives better, one person at a time.” I was drawn to West Virginia for the incredible opportunity to establish We care deeply about our patients and families in West the Rockefeller Neuroscience Institute with the compelling vision and Virginia, across the country, and around the world; our boldest commitment of Senator John D. Rockefeller IV and the leadership aspiration is to make their lives better, one person at a time. Our of West Virginia University. Deeply rooted in a culture of passion, team is passionate about the RNI and the opportunity to break purpose, and collaboration, the RNI is a unique institute with a bold barriers in neuroscience, impacting patient care and tackling the vision of advancing brain health and innovation in the treatment of big public health challenges facing us. neurological disease. We are bringing together the brightest minds in RNI IN THE NEWS We hope you enjoy learning more about the RNI and look research and patient care, deploying the latest technology solutions, Collision: No more forward to sharing our outcomes as we progress. and fostering key relationships with academic, private sector, and neurodegeneration? governmental partners. The British Medical Journal’s Warm regards, In our inaugural year, we have pioneered clinical trials to treat Ashley McKimm interviewed Alzheimer’s disease using focused ultrasound to open the blood- Dr. Rezai at Collision, North America’s fastest-growing brain barrier and to help those with chronic pain using a novel tech conference. non-opioid micropellet drug delivery technology. We have also May 23, 2019 deployed one of the largest longitudinal machine-learning and Ali R. Rezai, MD predictive data analytics frameworks in neuroscience with over Executive Chair, RNI 35,000 individual participants to date. John D. Rockefeller IV Chair in Neuroscience OUR MISSION With the latest technologies, an ecosystem of partners, and a truly WE ARE IMPROVING LIVES BY integrated approach, we are making tangible progress. Our breakthroughs in neuroscience are strengthening our efforts to combat public health challenges ranging from addiction to Alzheimer’s. Our collaboration with elite PIONEERING athletes and members of the military in optimizing human performance are leading to new innovations. We are breaking barriers in research and patient ADVANCES IN BRAIN HEALTH. care to better serve the people of West Virginia and beyond. Learn more about the RNI’s first-in-the-world clinical trials and the top-caliber experts joining us in our mission by visiting WVUMedicine.org/RNI 2 3 WVU MEDICINE ROCKEFELLER NEUROSCIENCE MEMBER SYSTEM AT-LARGE HOSPITALS INSTITUTE STRUCTURE WVU Medicine is the state’s largest health system and private COMPREHENSIVE. INTEGRATED. PATIENT-CENTRIC. employer. Comprised of 18 hospitals and nearly 100 clinics, the WVU 1. J.W. Ruby Memorial Hospital, WVU Health System’s mission is to improve the health of West Virginians Medicine’s flagship and all the people we serve through excellence in patient care, hospital in Morgantown research, and education. The Rockefeller Neuroscience Institute (RNI) “The RNI is designed to be both a world- 2. United Hospital Center is the premier multidisciplinary institute for class research institute and a healthcare patient care, research, and teaching in West 3. St. Joseph’s Hospital Virginia and the region. The RNI’s flagship provider to a diverse patient base. 4. Braxton County facilities are located on the Health Sciences This dual function gives the Institute Memorial Hospital campus in Morgantown, with more than unparalleled insight into the issues 5. Reynolds 1,000 dedicated team members across four 2,013,759 277,954 9,145 1,697 Memorial Hospital departments, patient care units, and research facing real patients, as it works to tackle Clinic Visits Emergency Telemedicine Helicopter laboratories. 6. Potomac Valley Room Visits Visits Patient Transfers the world’s biggest health challenges.” Hospital Albert L. Wright, Jr., PharmD, MHA 7. Berkeley President and CEO, Medical Center West Virginia University Health System 8. Camden Clark Medical Center 18,395 3,742 1,657 63,031 5,373 9. Jefferson Employees Students Beds Surgeries Births The RNI facilities on the WVU Health Sciences’ main campus in Morgantown. Medical Center 10. Summersville Regional Hancock Medical Center Hospital Harrison Brooke Clinic 15 Pennsylvania 14 Belmont Ohio MANAGED HOSPITALS 18 5 Maryland Erma Byrd Fayette 11. Wetzel County Hospital Biomedical Ohio Marshall Greene Monroe Research Center 11 Monongalia Allegany Washington Wetzel Garrett 12. Jackson General 1 Berkeley Innovation Washington Marion Hospital Preston 13 6 7 Center Mineral 9 Future Brain & 8 2 Taylor Doddridge Jefferson 13. Garrett Regional Harrison 17 Spine Hospital Wood Ritchie Barbour Tucker Grant Frederick Medical Center Lewis Hardy Gilmer 3 Chestnut Ridge 16 Warren 12 14. Wheeling Hospital Upshur Randolph Center Jackson Braxton 4 15. Harrison Community J.W. Ruby Memorial Putnam Virginia Hospital Clay Webster Physician Office Center: Cabell Hospital Kanawha Neuro Ambulatory 10 Pocahontas Nicholas AFFILIATE HOSPITALS and Education Greenbrier 16. Davis Health System Logan Raleigh Mingo WVU Medicine attracts 17. Broaddus Hospital patients from all 50 states Kentucky and internationally. 18. Barnesville Hospital McDowell Mercer 4 5 RNI BY THE NUMBERS CY 2018 Telemedicine offers patients in remote locations 4 2,904 144,959 130 5,619 access to world-class care offered at WVU Medicine DEPARTMENTS SURGICAL PROGRAM FACULTY TELEMEDICINE with the use of telecommunication technology. / Neuroscience PROCEDURES CLINIC VISITS The RNI has a rapidly growing telemedicine / Neurology VISITS program that treats three specialty areas: / Neurosurgery + / Behavioral Medicine + 6 18 21 and Psychiatry TELENEUROLOGY TELESTROKE TELEPSYCHIATRY 73 SITES SITES SITES + 135 RESIDENTS AND GAMMA KNIFE 21 POSTDOCTORAL Hancock PROCEDURES CLINICAL FELLOWS 7 LOCATIONS Brooke Pennsylvania AFFILIATE Ohio DEPARTMENTS Fayette Maryland + + Marshall / Oncology Ohio Monongalia / Ophthalmology Behavioral Medicine Wetzel Garrett Marion Berkeley / Orthopaedics 949 Neurosurgery 56 Preston / Otolaryngology Mineral NEURO- Neurology ADVANCED Jefferson / Pain / Anesthesiology INTERVENTIONAL PRACTICE Wood Barbour / Pathology PROCEDURES PROVIDERS Lewis Upshur / Radiology Randolph Jackson Calhoun Roane Virginia + Clay Kanawha Nicholas Pocahontas 718 Teleneurology and Telestroke Site Raleigh CLINICAL, Mingo RESEARCH, Wyoming Telestroke Site Kentucky ADMINISTRATIVE McDowell Mercer Telepsychiatry Site SUPPORT STAFF The RNI implements personalized, neuroscience- based strategies to oversee the monitoring, assessment, recovery, and improved performance for 15 RNI The RNI recognized the outstanding performance of 30,000+ TEAM MEMBERS faculty, trainees, and