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Teaching and Research Community College of Biological Sciences and Medical School faculty and students moved into the new $80 million Molecular and Cellular Biology Building this summer, creating a community of biologists who will work together to push the boundaries of knowledge. GENE WARS • DEVELOPMENTAL BIOLOGY • SUMMER AT LAKE ITASCA FROM THE DEAN Changes at CBS and the U Welcome to the first issue of Bio, the College of Biological Sciences’ new magazine, which replaces Frontiers and reflects the growth and change at CBS and in biology. We chose the name Bio, Greek for ‘life,’ because life is what we are about, from understanding how it works at the molecular level to pro- moting quality of life on our planet. Increasingly, the world’s problems are biological in nature: the effects of pollution on ecosystems; the Robert Elde, dean FALL 2002 ■ Vol. 1 No. 1 strain of global population growth on food supplies; and the threat of cancer, infectious diseases, and bioterrorism, to name a few. More and more, the world is DEAN Robert Elde turning to biologists for solutions. EDITOR As you can see, Bio brings us to you in living color. I was very glad to make this change Peggy Rinard because for me, biology is colors. There is nothing quite so disappointing as a black and white ADVISERS photo of a wild Minnesota orchid or a monarch butterfly. The cost difference between printing Janene Connelly in black and white and color has narrowed over the past few years. And this year, we were Director of Development and External Relations able to close the gap by doing design, production, and printing within the University rather Judd Sheridan than using outside services. Associate Dean This year is one of other important changes for the College of Biological Sciences and the John Anderson Associate Dean University of Minnesota. Over the summer xx faculty and staff made the long-awaited move into the new Molecular and Cellular Biology Building on the Minneapolis campus. This Department Heads David Bernlohr change, which makes us the only two-campus college at the U, is an evolutionary event in our Biochemistry, Molecular history that presents many new research and education opportunities. Biology, and Biophysics Robert Sterner A $1.7 million grant from the Howard Hughes Medical Institute to use Itasca as a base for Ecology, Evolution, and Behavior training more K-12 biology teachers also extends our reach. This is a distinct change from the Kate VandenBosch role the station has played in its 93 year history. Plant Biology Brian Van Ness There are big changes at the top, as well. With the departure of Mark Yudof, regents have Genetics, Cell Biology, and entrusted Bob Bruininks and Chris Maziar with leadership of the University. As veterans of the Development Yudof administration, they are very knowledgeable about the University and will provide great CONTRIBUTORS leadership. We are in good hands. I look forward to working with them. Emily Johnston Alumni Relations Coordinator Please read this issue of Bio and let me know what you think. I welcome your feedback. Just Justin Piehowski send an e-mail to [email protected]. Communications Intern Regards, GRAPHIC DESIGN Shawn Welch U of M Printing Services PRINTING U of M Printing Services Robert Elde, Dean Address correspondence to: e-mail: [email protected] Visit our Web site at www.cbs.umn.edu. COLLEGE OF BIOLOGICAL SCIENCES IN THIS ISSUE IN EVERY ISSUE 2 Abstracts Biodiversity, bugs, lions, Biodale, and books by faculty. 4 College News Itasca Science Teachers Institute, Cedar Creek Anniversary, 6 Microbial and Plant Genomics Building, CBS people. 6 E 15 Alumni News G A New BSAS President and Board Members, Class Notes, P Homecoming. Gene Wars 22 Calendar of Events Check out the line-up of fall events. COVER STORY 9 More Than a Building 0 The new Molecular and Cellular Biology Building provides $80 mil- 1 lion worth of labs and classrooms for CBS faculty and students. But 1 E the opportunities it creates for collaboration are worth even more. G A P FEATURES Cover Story 6 PLANT GENOMICS — Gene wars between plants and pests. 7 DEVELOPMENTAL BIOLOGY — Fruit fly genes provide human cancer clues. 12 STUDENT LIFE — Summer at Lake Itasca. 13 FIELD NOTES — IMAX film about Jane Goodall’s research opens soon. CAMPAIGN COUNTDOWN — Scholarships and fellowships are a top 14 4 priority as Campaign Minnesota enters the last year. 1 1 16 BIOTECHNOLOGY — Julie Kirahara, president of ATG Laboratories and MNBIO. E G A 18 Honor Roll P Scholarships CBS donors for FY 2002 The University of Minnesota is committed to the policy that all persons shall have equal access to its BIO is published three times a year by the programs, facilities, and employment without regard to race, color, creed, religion, national origin, sex, University of Minnesota College of Biological age, marital status, disability, public assistance status, veteran status, or sexual orientation. Sciences for alumni, faculty, staff, and friends Printed on elementally chlorine-free recycled paper containing 20 percent post-consumer waste. of the college. It is available in alternative for- mats upon request; please call 612-624-0774 On the Cover Located between Moos Tower and Jackson Hall on Washington Avenue, the new Molecular and or fax 612-624-2785. Cellular Biology Building is at the entrance of the Academic Health Center and across the street from the Institute of Technology. This strategic address will promote collaboration with health sciences and engineering. CATALYST ❙ FALL 2002 1 More kudos for Tilman Less buggy world David Tilman, McKnight Presidential The world is far less buggy than Professor of Ecology, was elected to the previously believed, according to a National Academy of Sciences in May. study involving CBS plant biol- Membership acknowledges distinguished ogist George Weiblen. The research and is considered one of the study, which lowers the estimate highest honors for U.S. scientists. He is from 31 million bug species (most- the only U of M faculty member elected ly insects, spiders, and crus- to the NAS this taceans) to four to six million, is year. Tilman’s based on the finding that insects research proves feed on plant families rather than Caterpillars (Lepidoptera) feed on the leaves of Ficus nodosa in the New Guinea rain forest. that grasslands individual plants. Weiblen, principal with many plant biologist on the team, says eating species. The total number species of plants that “bringing some reality” to estimates of species of all kinds on the earth is survive drought of worldwide biodiversity will enable sci- unknown. Estimates range from 7 million better and pro- entists to get a better handle on how fast to more than 50 million. Of the 1.8 mil- duce more vege- species are being lost. The study, funded lion species documented thus far, about tation than land by the National Science Foundation, TIM RUMMELHOFF half are arthropods. The study was with only a few looked at 51 rain forest plants in New species. The NAS, reported in the April 25 issue of Nature. ■ Guinea and more than 900 types of plant- which acts as an adviser to the federal government in matters of science and technology, was established in 1863 and Smaller, lighter, cheaper, DNA chip reader has 1,907 active members. Other NAS Mark Sanders and Martin Blumenfeld toaster and weighs 15 pounds, would cost members from ecology, evolution, and have invented a DNA chip reader that is half as much as the least expensive behavior include emeriti professors Herb smaller, lighter, and cheaper than any machine now on the market without sac- Wright, Margaret Davis, and Eville other models on the market. An associate rificing technology. DNA chip scanners Gorham. “I did not do this alone,” says professor of genetics, cell biology, and now available are about the size of a copy Tilman. “Everything we accomplish in life development, Blumenfeld created the machine, weigh up to 100 pounds, and is the result of team work. A lot of the company Blizzard Genomics to commer- cost $75,000. The U has filed three credit for these accomplishments goes to cialize their invention, which relies on LED patents for the device. Blizzard Genomics my graduate students and colleagues.” technology rather than costly lasers. LED has raised $1.6 million to produce and Tilman was also named a Regents technology is used in traffic lights, tail market this invention, and is attempting to Professor—the University’s highest lights of cars, and stadium scoreboard raise another $5 million Sanders is direc- honor for faculty—this spring. ■ lighting. The reader, which is the size of a tor of the CBS Imaging Center. ■ Viral transmission in lions Craig Packer, ecology, evolution, and behavior, has received a five-year grant of $1,482,000 from the National Science Foundation for his research project, “Viral Transmission Dynamics in the Serengeti.” His study will investigate the transmis- sion dynamics of three viral pathogens: rabies, canine distemper virus, and canine parvovirus, identifying reservoirs of infection through a combination of approaches that include intervention trials, genetic analyses, and disease surveillance. Of the emerging infectious diseases, zoonotic and generalist viral pathogens pose a par- ticular threat to public health and biodiversity. The effective control of these dis- eases requires both the identification of reservoirs of infection and an understand- Packer will study viral transmission among prides (social ing of viral transmission dynamics within complex host assemblages. Yet for most groups) of lions in Tanzania’s Serengeti National Park and emerging infectious diseases, reservoirs remain to be identified and little is known Ngorongoro Crater. about mechanisms by which infections are maintained.