Lighting the Spark Quantum Science at Harvard to Note Colloquy
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Using Web-Based Annotation Tools for Bioinformatic Analyses of Proteomics Data
Using web-based annotation tools for bioinformatic analyses of proteomics data Kasper Lage, PhD Massachusetts General Hospital Harvard Medical School the Broad Institute Overview of this session 1) Biological networks 2) Annotating genetic and proteomic data using biological networks 3) Tissue-specific networks with disease resolution 4) Emerging resources at the Broad Institute What is a biological network? Jeong et al., Nature 2001 1) Gene expression correlations 2) Protein-protein interactions 3) Co-mentioning in text D 4) Synthetic lethality 5) TF binding 6) Pathway database mining 7) Epigenetic data 8) All of the above Building a human protein-protein interaction network - InWeb Email [email protected] if you want to use the data. Lage, Karlberg et al., Nat. Biotech., 2007 Lage, Hansen et al. PNAS, 2008 Lage et al., Mol Syst Biol, 2010 Rossin et al., PLoS Genetics, 2011 Lage et al., PNAS, 2012 Social human networks D are a good model for understanding biological networks Social networks People are represented by “nodes”, work related interactions by “edges” daily weekly monthly Social networks People that work together are close to each other in the network daily weekly monthly Social networks People that work together are close to each other in the network daily weekly monthly Social networks People that work together are close to each other in the network daily weekly monthly Lone< wolf Social networks People that work together are close to each other in the network Do loci connect more than a random expectation? Quantify -
Senior Counsel's Office
Senior Counsel’s Office In its fifth year, fiscal year 2004, the Senior Counsel’s Office is MIT’s central in‐house counsel’s office, providing comprehensive legal services and counseling on MIT matters in all areas of concern to the academy and the administration (except intellectual property law). The office represents MIT’s president, provost, executive vice president, and chancellor, as well as the deans, vice presidents, the departments, laboratories, and research centers, and administrative offices. We also arrange for and manage outside legal services when needed and oversee all litigation. Our office includes MIT’s senior counsel Jamie Lewis Keith, contracts counsel Margaret Brill, and litigation and risk management counsel Mark DiVincenzo, as well as a law clerk, Kathryn Johnson. (In FY2004 our office also included a part‐time environmental counsel. In FY2005 the office will include an associate counsel.) We are problem solvers and strategic‐thinking partners for our clients. We strive to be enablers, helping MIT’s senior officers, faculty, and staff to accomplish their mission‐critical objectives and to make informed decisions. Our office also brings the lessons learned from litigation, other disputes, and major transactions back to the MIT community through counseling and education. These lessons support management and faculty initiatives to minimize and avoid those reputational, financial, operational, and legal risks that can be appropriately managed, while still achieving MIT’s core mission. The Senior Counsel’s Office advises -
HBS Annual Report 2008
2 0 0 8 h a r v a r d u n i v harvard university e r s i t y f i financial report n a n c i a l r e p o r t fiscal year 2008 001215 We want all students who might dream of a Harvard “ education to know that it is a realistic and affordable option . Education is fundamental to the future of individuals and the nation, and we are determined to do our part to restore its place as an engine of opportunity, rather than a source An upperclass student in Kirkland House sketches during her free time. of financial stress…This is a huge investment for Harvard, but there is no more important commitment we could make. Excellence and opportunity must go hand in hand. ” —President Drew Gilpin Faust announcing the Middle Income Financial Aid Initiative, December 10, 2007 2 message from the president 3 financial highlights s t 8 annual report of the harvard n e t management company n o 15 report of independent auditors c f financial statements o 16 e l b 20 notes to financial statements a t Message from the President I am pleased to present Harvard University’s financial report for fiscal 2008. Under very challenging market conditions, we achieved endowment returns of 8.6%, raising the endowment to $36.9 billion. Income from the endowment contributed approximately one-third of the University’s operating budget, while also supporting substantial capital outlays. In addition, our alumni and friends contributed $690.1 million during fiscal 2008, the second highest level of fundraising receipts in the University’s history. -
CURRICULUM VITAE – June 13, 2017
Chris Cotsapas PhD CURRICULUM VITAE – June 13, 2017 Education ARCS Imperial College, London UK (Biochemistry) 2000 BSc Imperial College, London UK (Biochemistry) 2000 PhD University of New South Wales, Sydney, Australia (Biochemistry & Molecular Genetics) 2007 Career/Academic Appointments: 2005-2007 Research Associate, Center for Human Genetics Research, MGH (Boston, MA) 2007-2010 Research Fellow, Center for Human Genetics Research, MGH (Boston, MA) 2005-present Research Affiliate, Broad Institute of MIT and Harvard (Cambridge, MA) 2010-present Visiting Faculty, Analytical/Translational Genetics Unit, MGH (Boston, MA) 2010-2016 Assistant Professor, Dept. of Neurology, Yale School of Medicine (New Haven, CT) 2011-2016 Assistant Professor, Dept. of Genetics, Yale School of Medicine (New Haven, CT) 2011-present Research Affiliate, Stanley Center for Psychiatric Research (Boston, MA) 2016-present Associate Professor, Dept. of Neurology, Yale School of Medicine (New Haven, CT) 2016-present Associate Professor, Dept. of Genetics, Yale School of Medicine (New Haven, CT) Funding Record Current Grants Agency: NIH/NIAID I.D.# R01 AI122220 Title: “Genomics of NFkB-mediated gene regulation in multiple sclerosis” P.I.: Chris Cotsapas PhD Percent effort: 12% Total costs for project period: $1,827,500 Project period: 09/01/2015 – 08/31/2020 Agency: European Commission (Horizon 2020 program) I.D.#: 733161 Title: “MultipleMS: Multiple manifestations of genetic and non-genetic factors in multiple sclerosis disentangled with a multi-omics approach to accelerate -
Environmental Racism and Environmental Justice in Boston, 1900 to 2000
The University of Maine DigitalCommons@UMaine Electronic Theses and Dissertations Fogler Library Summer 8-22-2019 "The Dream is in the Process:" Environmental Racism and Environmental Justice in Boston, 1900 to 2000 Michael J. Brennan University of Maine, [email protected] Follow this and additional works at: https://digitalcommons.library.umaine.edu/etd Recommended Citation Brennan, Michael J., ""The Dream is in the Process:" Environmental Racism and Environmental Justice in Boston, 1900 to 2000" (2019). Electronic Theses and Dissertations. 3102. https://digitalcommons.library.umaine.edu/etd/3102 This Open-Access Thesis is brought to you for free and open access by DigitalCommons@UMaine. It has been accepted for inclusion in Electronic Theses and Dissertations by an authorized administrator of DigitalCommons@UMaine. For more information, please contact [email protected]. “THE DREAM IS IN THE PROCESS:” ENVIRONMENTAL RACISM AND ENVIRONMENTAL JUSTICE IN BOSTON, 1900 TO 2000 By Michael J. Brennan B.S. University of Maine at Farmington, 2001 A.L.M. Harvard University Extension School, 2012 A DISSERTATION Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy (American History) The Graduate School The University of Maine August 2019 Advisory Committee: Richard Judd, Professor Emeritus of History Elizabeth McKillen, Adelaide & Alan Bird Professor of History Liam Riordan, Professor of History Jacques Ferland, Associate Professor of History and Graduate Coordinator of History Program Roger J.H. King, Associate Professor of Philosophy THE DREAM IS IN THE PROCESS: ENVIRONMENTAL RACISM AND ENVIRONMENTAL JUSTICE IN BOSTON, 1900 TO 2000 By: Michael J. Brennan Dissertation Advisor: Dr. Richard Judd An Abstract of the Dissertation Presented in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy in American History (August 2019) The following work explores the evolution of a resident-directed environmental activism that challenged negative public perception to redevelop their community. -
The Gamut Archives Publications
Cleveland State University EngagedScholarship@CSU The Gamut Archives Publications Summer 1988 The Gamut: A Journal of Ideas and Information, No. 24, Summer 1988 Cleveland State University Follow this and additional works at: https://engagedscholarship.csuohio.edu/gamut_archives Part of the Arts and Humanities Commons, Business Commons, and the Social and Behavioral Sciences Commons How does access to this work benefit ou?y Let us know! Recommended Citation Cleveland State University, "The Gamut: A Journal of Ideas and Information, No. 24, Summer 1988" (1988). The Gamut Archives. 22. https://engagedscholarship.csuohio.edu/gamut_archives/22 This Book is brought to you for free and open access by the Publications at EngagedScholarship@CSU. It has been accepted for inclusion in The Gamut Archives by an authorized administrator of EngagedScholarship@CSU. For more information, please contact [email protected]. First Prize $1 ,000 Three Second Prizes of $250 each The four winning entries will be published in The Gamut in 1989. MANUSCRIPT REOUIREMENTS Entry should be ashort story between 1000 and 5000 words long. Entries must be original , previously unpublished, and not under consideration elsewhere. Each entry should be typed (or printed in near letter quality), with adark ribbon, double spaced. Clear photocopies are acceptable. Pages should be numbered , with author's name or short title on each sheet. A cover sheet should include the title, number of words, and author's name, address, phone number, and social security number. , ENTRY FEE Each entry must be accompanied by a fee of $5 .00 . Make checks payable to The Gamut. One entry fee is waived for each subscriber to The Gamut. -
Boston Tech Hub Faculty Working Group Annual Report: 2019-2020
BOSTON TECH HUB FACULTY WORKING GROUP Annual Report 2019–2020 Technology and Public Purpose Project Belfer Center for Science and International Affairs Harvard Kennedy School 79 JFK Street Cambridge, MA 02138 www.belfercenter.org/TAPP Harvard John A. Paulson School of Engineering and Applied Sciences 29 Oxford St., Cambridge, MA 02138 www.seas.harvard.edu Statements and views expressed in this report are solely those of the authors and do not imply endorsement by Harvard University, Harvard Kennedy School, Harvard Paulson School, or the Belfer Center for Science and International Affairs. Design and Layout by Andrew Facini Copyright 2020, President and Fellows of Harvard College Printed in the United States of America BOSTON TECH HUB FACULTY WORKING GROUP Annual Report 2019-2020 Table of Contents Foreword ........................................................................................................................1 FWG Members and Guests .........................................................................................5 Introduction ................................................................................................................ 13 Summary ..................................................................................................................... 14 FWG Session Briefs: Fall 2019 ................................................................................19 FWG Session Briefs: Spring 2020 ..........................................................................31 Carol Rose, Executive Director -
JUNIOR FAMILY WEEKEND Feb
JUNIOR FAMILY WEEKEND Feb. 21–22, 2020 CLASS OF 2021 PARKING INFORMATION Welcome Parents Parking is available at the 52 Oxford Street Garage from 5:00pm Thursday to 2:00pm on Sunday. Notify the Parking Services Monitor at the booth that you are attending Junior and Families! Family Weekend to receive a complimentary access ticket. VISITING THE LIBRARIES Thank you for joining us for Junior Family Weekend. Over the Families are invited to visit campus libraries during regular next two days, as you spend time on campus, you will have the library hours (see library.harvard.edu/libraries for hours opportunity to glimpse the transformative power of Harvard and locations). Please bring your family button. College that our students experience each and every day. The opportunity to visit classes and engage in discussions with ON CAMPUS DINING IN THE HOUSES faculty members will offer you a sense of where the intellectual Families are welcome to dine in House dining halls while they transformation begins for our students. are on campus. The House Dining halls do not accept credit cards. Meal times and rates: At the same time, the many open houses and receptions in our • Breakfast (7:30-10:00am, Thur-Sat): $9.25 residential communities will allow you to see how our campus • Continental Breakfast (7:30-10:00am, Sun): $8.00 comes together in ways that support the social transformation • Brunch (11:30am-2:15pm, Sun): $14.75 of our students. And finally, we hope that your time on campus • Lunch (12:00-2:15pm Thur-Fri): $14.75 meeting your student’s peers and their families will open a • Complimentary Lunch (11:30am-2:15pm, Sat): Hosted window to the rich diversity of experiences and perspectives by Dean of Students Office that contribute to the personal transformation for our • Dinner (5:00-7:15pm, Thur-Sun): $18.25 students. -
Angela N. Koehler
Angela N. Koehler Broad Institute of MIT and Harvard Office: 617-714-7364 Chemical Biology Program Fax: 617-714-8943 7 Cambridge Center Email: [email protected] Cambridge, MA 02142 Website: www.broadinstitute.org/node/2445 Education Ph.D. Chemistry, Harvard University, 2003 B.A. Biochemistry and Molecular Biology, Reed College, 1997 Research Experience Investigator, Chemical Biology Program, Broad Institute 2009-present Project & Center Manager, Broad NCI Cancer Target Discovery and Development (CTD2) Center 2010-2012 Institute Fellow, Chemical Biology Program, Broad Institute 2003-2009 Director, Ligand Discovery, NCI Initiative for Chemical Genetics (ICG) at Harvard 2003-2009 Graduate Student, Department of Chemistry and Chemical Biology, Harvard University 1998-2003 Laboratory of Professor Stuart L. Schreiber Thesis: Small molecule microarrays: A high-throughput tool for discovering protein-small molecule interactions Researcher, Department of Chemistry, California Institute of Technology 1997-1998 Laboratory of Professor Barbara Imperiali Project: Biochemical reconstitution of the oligosaccharyltransferase (OST) complex Undergraduate Researcher, Department of Chemistry, Reed College 1995-1997 Laboratory of Professor Arthur Glasfeld Co-mentored by Professor Richard G. Brennan at Oregon Health Sciences University Thesis: Biochemical and structural characterization of the tRNA-modifying enzyme QueA from Escherichia coli Teaching Experience Research Advisor to postdoctoral fellows, undergraduates, high school students, and staff scientists 2003-present Broad Institute of MIT and Harvard Instructor, Biochemical Sciences Research (BS91r) 2004-2006, 2010-2011 Harvard University Associated Instructor, Experimental Research in the Life Sciences (LS100r) 2009 Harvard University Associated Instructor, Experimental Molecular and Cellular Biology (MCB100) 2004-2006 Harvard University Teaching Fellow, Chemical Biology (Chem 170) 1999, 2000 Harvard University, Professor David R. -
BIOGRAPHICAL SKETCH NAME: Arlene H. Sharpe Era COMMONS
OMB No. 0925-0001 and 0925-0002 (Rev. 12/2020 Approved Through 02/28/2023) BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors. Follow this format for each person. DO NOT EXCEED FIVE PAGES. NAME: Arlene H. Sharpe eRA COMMONS USER NAME (credential, e.g., agency login): asharpe POSITION TITLE: George Fabyan Professor of Comparative Pathology EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.) DEGREE Completion (if Date FIELD OF STUDY INSTITUTION AND LOCATION applicable) MM/YYYY Radcliffe College, Cambridge, MA AB 05/1975 Biochemistry Harvard University, Cambridge, MA PhD 05/1981 Microbiology Harvard Medical School, Boston, MA MD 05/1982 Medicine A. Personal Statement My laboratory investigates T cell costimulation and its immunoregulatory functions. My laboratory focUses on the roles of T cell costimUlatory and coinhibitory pathways in regUlating immUne responses needed for the indUction and maintenance of T cell tolerance and effective antimicrobial and antitumor immunity. My laboratory has been at the forefront of this field for two decades. We have discovered T cell costimulatory pathways, and elucidated their functions, inclUding the functions of B7-1 and B7-2, CTLA-4, ICOS, PD-1 and PD-1 ligands. We are also involved in stUdies aimed at translating fUndamental Understanding of T cell costimUlation into new therapies for autoimmune diseases, viral infections, and cancer. Understanding how costimulatory pathways regulate tissUe inflammation, tolerance and anti-tumor immUnity is an important aspect of my cUrrent research. -
Ronni Gura Sadovsky
RONNI GURA SADOVSKY Department of Philosophy Phone: 314-520-7837 Emerson Hall 209a, Harvard University Email: [email protected] 25 Quincy Street, Cambridge, MA 02138 EDUCATION Harvard University, Ph.D. Candidate, Department of Philosophy, May 2020 (anticipated) Harvard Law School, J.D., magna cum laude, 2014 The Hebrew University in Jerusalem, Visiting Fellow 2008–2009 Swarthmore College, B.A. Philosophy and Linguistics, highest honors, 2008 DISSERTATION Title: Political Etiquette Committee: Tommie Shelby, Gina Schouten, Lucas Stanczyk Some social norms, such as table-setting conventions, are morally neutral. Others, such as pronoun choice, are morally charged. My dissertation offers an analysis of a category of morally charged social norms that I call political etiquette. I propose that we understand political etiquette as a system of conventions whereby we assure members of vulnerable groups that they can expect treatment in accordance with their rightful status. My account partially vindicates political etiquette’s claim to moral force, but also sheds light on its limitations. I argue that some of these limitations can be ameliorated through widespread acceptance of my interpretation of political etiquette. Areas of Specialization: Political Philosophy, Moral Philosophy, Social Philosophy, Applied Ethics Areas of Competence: Philosophy of Law, Philosophy of Race, Feminist Philosophy, Logic WORKS IN PROGRESS “Political Etiquette’s Moral Force” (under review; draft available upon request) “Assurance and the Optics of Respect” “Political Etiquette as a Vehicle for Moral Education” “Dysfunctions of Political Etiquette” “You Shouldn’t Have to Wonder” “Moral Cults” PUBLICATION Recent Case, Yonaty v. Mincolla, 126 Harv. L. Rev. 852, 856–58 (2013). (student note) Sadovsky Curriculum Vitae 2 ACADEMIC AWARDS AND FELLOWSHIPS Harvard Graduate School of Arts and Sciences Harvard University Dissertation Completion Fellowship, 2019–2020 Edmond J. -
Office for the Arts and Office of Career Services Announce 2009 Recipients of Artist Development Fellowships
P R E S S R E L E A S E For Immediate March 11, 2009 Release For More Information Stephanie Troisi ([email protected]), 617.495.8676 Office for the Arts and Office of Career Services Announce 2009 Recipients of Artist Development Fellowships FOURTEEN UNDERGRADUATE ARTISTS AWARDED FELLOWSHIPS TO FURTHER ARTISTIC DEVELOPMENT The Office for the Arts at Harvard (OFA) and Office of Career Services (OCS) are pleased to announce the 2009 recipients of the Artist Development Fellowship (ADF). This program supports the artistic development of students demonstrating unusual accomplishment and/or evidence of significant artistic promise. The ADF program represents Harvard’s deep commitment to arts practice on campus and provides financial support for the creative and professional growth of student artists. Now in its third year, ADF has awarded 40 Fellowships and provided over $120,000 in funding support. The Council on the Arts, a standing committee of the Faculty of Arts and Sciences, oversees Fellowship award decisions. Council on the Arts members at the time of selection were: Jack Megan (chair), Director, Office for the Arts; Elizabeth Bergmann, Director, Office for the Arts Dance Program; S. Allen Counter, Director, Harvard Foundation; Deborah Foster, Senior Lecturer in Folklore and Mythology; Jorie Graham, Boylston Professor of Rhetoric and Oratory; Cathleen McCormick, Director of Programs, Office for the Arts; Nancy Mitchnick, Rudolf Arnheim Lecturer on Studio Arts, Visual and Environmental Studies; Robert J. Orchard, Executive Director of the American Repertory Theatre and the Institute for Advanced Theatre Training, and Director of the Loeb Drama Center at Harvard University; Alex Rehding, Professor of Music Theory, Graduate Advisor in Theory; and Marcus Stern, Associate Director, American Repertory Theatre and the A.R.T./MXAT Institute for Advanced Theatre Training.