A Theory of Matriarchism: the Universal Origin of Humanity
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Demographic Uniformitarianism: the Theoretical Basis of Prehistoric Demographic Research 5 and Its Cross-Disciplinary Challenges
1 Accepted for publication 16/03/2020 at Philosophical Transactions of the Royal Society B (Special 2 Issue: Cross-Disciplinary Approaches to Prehistoric Demography) 3 4 Demographic uniformitarianism: the theoretical basis of prehistoric demographic research 5 and its cross-disciplinary challenges 6 Jennifer C. French1 & Andrew T. Chamberlain2 7 1 UCL Institute of Archaeology, 31-34 Gordon Square, London WC1H 0PY UK 8 [email protected] 9 2 Department of Earth and Environmental Sciences, University of Manchester, Stopford Building, 10 Oxford Road, Manchester, M13 9PT, [email protected] 11 12 13 Abstract 14 A principle of demographic uniformitarianism underpins all research into prehistoric demography 15 (palaeodemography). This principle—which argues for continuity in the evolved mechanisms 16 underlying modern human demographic processes and their response to environmental stimuli 17 between past and present— provides the cross-disciplinary basis for palaeodemographic 18 reconstruction and analysis. Prompted by the recent growth and interest in the field of prehistoric 19 demography, this paper reviews the principle of demographic uniformitarianism, evaluates how it 20 relates to two key debates in palaeodemographic research and seeks to delimit its range of 21 applicability to past human and hominin populations. 22 23 Keywords: Prehistoric demography; Uniformitarianism; Population dynamics; Life History; Archaic 24 hominins 25 1. Introduction 26 Like many historical sciences, prehistoric demography relies on a doctrine of uniformitarianism for 27 some of its foundational principles. Uniformitarianism is the adherence to the axiom that processes 28 that occurred in the past (and so cannot be directly experienced) were nonetheless likely to 29 resemble those that are observable in the present day. -
Grandmothers Matter
Grandmothers Matter: Some surprisingly controversial theories of human longevity Introduction Moses Carr >> Sound of rolling tongue Wanda Carey >> laughs Mariel: Welcome to Distillations, I’m Mariel Carr. Rigo: And I’m Rigo Hernandez. Mariel: And we’re your producers! We’re usually on the other side of the microphones. Rigo: But this episode got personal for us. Wanda >> Baby, baby, baby… Mariel: That’s my mother-in-law Wanda and my one-year-old son Moses. Wanda moved to Philadelphia from North Carolina for ten months this past year so she could take care of Moses while my husband and I were at work. Rigo: And my mom has been taking care of my niece and nephew in San Diego for 14 years. She lives with my sister and her kids. Mariel: We’ve heard of a lot of arrangements like the ones our families have: grandma retires and takes care of the grandkids. Rigo: And it turns out that across cultures and throughout the world scenes like these are taking place. Mariel: And it’s not a recent phenomenon either. It goes back a really long time. In fact, grandmothers might be the key to human evolution! Rigo: Meaning they’re the ones that gave us our long lifespans, and made us the unique creatures that we are. Wanda >> I’m gonna get you! That’s right! Mariel: A one-year-old human is basically helpless. We’re special like that. Moses can’t feed or dress himself and he’s only just starting to walk. Gravity has just become a thing for him. -
GLOSSARY of MEDICAL and ANATOMICAL TERMS
GLOSSARY of MEDICAL and ANATOMICAL TERMS Abbreviations: • A. Arabic • abb. = abbreviation • c. circa = about • F. French • adj. adjective • G. Greek • Ge. German • cf. compare • L. Latin • dim. = diminutive • OF. Old French • ( ) plural form in brackets A-band abb. of anisotropic band G. anisos = unequal + tropos = turning; meaning having not equal properties in every direction; transverse bands in living skeletal muscle which rotate the plane of polarised light, cf. I-band. Abbé, Ernst. 1840-1905. German physicist; mathematical analysis of optics as a basis for constructing better microscopes; devised oil immersion lens; Abbé condenser. absorption L. absorbere = to suck up. acervulus L. = sand, gritty; brain sand (cf. psammoma body). acetylcholine an ester of choline found in many tissue, synapses & neuromuscular junctions, where it is a neural transmitter. acetylcholinesterase enzyme at motor end-plate responsible for rapid destruction of acetylcholine, a neurotransmitter. acidophilic adj. L. acidus = sour + G. philein = to love; affinity for an acidic dye, such as eosin staining cytoplasmic proteins. acinus (-i) L. = a juicy berry, a grape; applied to small, rounded terminal secretory units of compound exocrine glands that have a small lumen (adj. acinar). acrosome G. akron = extremity + soma = body; head of spermatozoon. actin polymer protein filament found in the intracellular cytoskeleton, particularly in the thin (I-) bands of striated muscle. adenohypophysis G. ade = an acorn + hypophyses = an undergrowth; anterior lobe of hypophysis (cf. pituitary). adenoid G. " + -oeides = in form of; in the form of a gland, glandular; the pharyngeal tonsil. adipocyte L. adeps = fat (of an animal) + G. kytos = a container; cells responsible for storage and metabolism of lipids, found in white fat and brown fat. -
Throughout the World, Human Skin Color Has Evolved to Be Dark
AFEATURE ARTICLE FROM... OCTOBER 2002 Throughout the world, human skin color has evolved to be dark enough to prevent sunlight from destroy'ng the nutrient folate but light e ough to foster the production of vitamin By Nina G. Jablonski and George Chaplin Among primates, only humans have a mostly naked skin that comes in different colors. Geogra phers and anthropologists have long recognized that the distribution of skin colors among indigenous popula tions is not random: darker peoples tend to be found nearer the equator, lighter ones closer to the poles. For years, the prevailing theory has been that darker skins evolved to protect against skin cancer. But a series of dis coveries has led us to construct a new framework for understanding the evolutionary basis of variations in hu man skin color. Recent epidemiological and physiological evidence suggests to us that the worldwide pattern ofhuman skin color is the product of natural selection acting to regulate the effects ofthe sun's ultraviolet (UV) radiation on key nutrients crucial to reproductive success. From Hirsute to Hairless THE EVOLUTION OF SKIN PIGMENTAnON is linked with that ofhairlessness, and to comprehend both these stories, we need to page back in human history. Human beings have been evolving as an independent lineage of apes since at least seven million years ago, when our immediate ancestors diverged from those of our closest relatives, chim panzees. Because chimpanzees have changed less over time than humans have, they can provide an idea of what human anatomy and physiology must have been like. Chimpanzees' skin is light in color and is covered by hair over most of their bodies. -
Unit #2 - Abdomen, Pelvis and Perineum
UNIT #2 - ABDOMEN, PELVIS AND PERINEUM 1 UNIT #2 - ABDOMEN, PELVIS AND PERINEUM Reading Gray’s Anatomy for Students (GAFS), Chapters 4-5 Gray’s Dissection Guide for Human Anatomy (GDGHA), Labs 10-17 Unit #2- Abdomen, Pelvis, and Perineum G08- Overview of the Abdomen and Anterior Abdominal Wall (Dr. Albertine) G09A- Peritoneum, GI System Overview and Foregut (Dr. Albertine) G09B- Arteries, Veins, and Lymphatics of the GI System (Dr. Albertine) G10A- Midgut and Hindgut (Dr. Albertine) G10B- Innervation of the GI Tract and Osteology of the Pelvis (Dr. Albertine) G11- Posterior Abdominal Wall (Dr. Albertine) G12- Gluteal Region, Perineum Related to the Ischioanal Fossa (Dr. Albertine) G13- Urogenital Triangle (Dr. Albertine) G14A- Female Reproductive System (Dr. Albertine) G14B- Male Reproductive System (Dr. Albertine) 2 G08: Overview of the Abdomen and Anterior Abdominal Wall (Dr. Albertine) At the end of this lecture, students should be able to master the following: 1) Overview a) Identify the functions of the anterior abdominal wall b) Describe the boundaries of the anterior abdominal wall 2) Surface Anatomy a) Locate and describe the following surface landmarks: xiphoid process, costal margin, 9th costal cartilage, iliac crest, pubic tubercle, umbilicus 3 3) Planes and Divisions a) Identify and describe the following planes of the abdomen: transpyloric, transumbilical, subcostal, transtu- bercular, and midclavicular b) Describe the 9 zones created by the subcostal, transtubercular, and midclavicular planes c) Describe the 4 quadrants created -
Anthro Notes : National Museum of Natural History Bulletin for Teachers
AnthroNotes Volume 32 No. 1 Spring 2011 WHY HUMAN SKIN COMES IN COLORS by Nina G. JabIonski look at a of predicted skin pigmentation, pigmentation provides one of the best examples map human we Skin find that all people are varying shades of brown. The in- of evolution by natural selection acting on the human tensity of their brownness and their ability to tan is related body. The fact that skin color has been so responsive to the UVR in the place where their ancestors came from. to evolutionary forces is fascinating, and one that is impor- societies tant for modern human to understand. Similar In the last 1 0,000 years, we have gotten better and skin colors — both dark and light — have evolved indepen- better at protecting ourselves against the extremes of UVR dently multiple times in human history. When we think of by cultural means. Sewn clothing and constructed shelters how races have been defined in the past using skin color, now protect us from strong sunlight and augment the pro- we can immediately see the problem. When the same skin tection afforded by natural melanin pigmentation. In far color has evolved many times independently in different northern environments, diets composed of vitamin D-rich places, its value as a unique maker of identity is eliminated foods like oily fish and marine mammals supplement the and the race so defined is rendered nonsensical. We are all vitamin D we can make in our skin under low UVR con- "hue-mans"! ditions. The major problem we face today is that we are able to travel so far so fast. -
Genetics of Hair and Skin Color
11 Sep 2003 14:51 AR AR201-GE37-04.tex AR201-GE37-04.sgm LaTeX2e(2002/01/18) P1: GCE 10.1146/annurev.genet.37.110801.143233 Annu. Rev. Genet. 2003. 37:67–90 doi: 10.1146/annurev.genet.37.110801.143233 Copyright c 2003 by Annual Reviews. All rights reserved First published online as a Review in Advance on June 17, 2003 GENETICS OF HAIR AND SKIN COLOR Jonathan L. Rees Systems Group, Dermatology, University of Edinburgh, Lauriston Buildings, Lauriston Place, Edinburgh, EH3 9YW, United Kingdom; email: [email protected] Key Words melanin, melanocortin 1 receptor (MC1R), eumelanin, pheomelanin, red hair ■ Abstract Differences in skin and hair color are principally genetically deter- mined and are due to variation in the amount, type, and packaging of melanin polymers produced by melanocytes secreted into keratinocytes. Pigmentary phenotype is genet- ically complex and at a physiological level complicated. Genes determining a number of rare Mendelian disorders of pigmentation such as albinism have been identified, but only one gene, the melanocortin 1 receptor (MCR1), has so far been identified to explain variation in the normal population such as that leading to red hair, freckling, and sun-sensitivity. Genotype-phenotype relations of the MC1R are reviewed, as well as methods to improve the phenotypic assessment of human pigmentary status. It is argued that given advances in model systems, increases in technical facility, and the lower cost of genotype assessment, the lack of standardized phenotype assessment is now a major limit on advance. CONTENTS INTRODUCTION ..................................................... 68 BIOLOGY OF HUMAN PIGMENTATION ................................ 69 by San Jose State University on 10/05/10. -
Human Origin Sites and the World Heritage Convention in Eurasia
World Heritage papers41 HEADWORLD HERITAGES 4 Human Origin Sites and the World Heritage Convention in Eurasia VOLUME I In support of UNESCO’s 70th Anniversary Celebrations United Nations [ Cultural Organization Human Origin Sites and the World Heritage Convention in Eurasia Nuria Sanz, Editor General Coordinator of HEADS Programme on Human Evolution HEADS 4 VOLUME I Published in 2015 by the United Nations Educational, Scientific and Cultural Organization, 7, place de Fontenoy, 75352 Paris 07 SP, France and the UNESCO Office in Mexico, Presidente Masaryk 526, Polanco, Miguel Hidalgo, 11550 Ciudad de Mexico, D.F., Mexico. © UNESCO 2015 ISBN 978-92-3-100107-9 This publication is available in Open Access under the Attribution-ShareAlike 3.0 IGO (CC-BY-SA 3.0 IGO) license (http://creativecommons.org/licenses/by-sa/3.0/igo/). By using the content of this publication, the users accept to be bound by the terms of use of the UNESCO Open Access Repository (http://www.unesco.org/open-access/terms-use-ccbysa-en). The designations employed and the presentation of material throughout this publication do not imply the expression of any opinion whatsoever on the part of UNESCO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. The ideas and opinions expressed in this publication are those of the authors; they are not necessarily those of UNESCO and do not commit the Organization. Cover Photos: Top: Hohle Fels excavation. © Harry Vetter bottom (from left to right): Petroglyphs from Sikachi-Alyan rock art site. -
Infective Endocarditis After Body Art: a Review of the Literature and Concerns Myrna L
JOURNAL OF ADOLESCENT HEALTH ELSEVIER Journal of Adolescent Health 43 (2008) 217-225 Review article Infective Endocarditis After Body Art: A Review of the Literature and Concerns Myrna L. Armstrong, Ed.D., RN, FAANa·*, Scott DeBoer R.N., M.S.N., CEN, CCRN, CFRNb and Frank Cetta, M.D., FACCc aschool of Nursing , Texas Tech University H ealth Sciences Center at Hig hlpnd Lak es, Marble Fall s, Texas bUniversity of Chicago Hospitals , Peds-R-Us Medical Education, Dye r, Indiana cDivision of Pediatri c Cardiology, Mayo Clinic, Rochester, Minnesota Manuscript received October 10, 2007 ; manuscript accepted February 9, 2008 Abstract Purpose:_ Infective endocarditis (IE) is a rare but dangerous complication of tattooing and body piercing in adolescents and young adults 15-30 years of age, with and without congenital heart disease (CHD). Because body art, including tattooing and piercing, is increasing and IE cases continue to be reported in the literature, a longitudinal assessment of IE and body art cases is important to examine for trends . Methods: A 22-year (1985-2007) longitudinal electronic MedUne and Scopus review of all published cases of IE and body art was conducted . Results: In all, 22 specific cases ofiE spanning 1991-2007 have been reported that were associated with piercing the tongue (seven), ear lobes (six), navel (five), lip (one), nose (one), and nipple (one), and reported in one heavily tattooed person; other general IE cases have also been mentioned . Twelve cases were in females , and one patient died; nine of these individuals had CHD. Twenty-one cases have been published in the 10 years from 1997-2007. -
Teaching Diversity: the Science You Need to Know to Explain Why Race
SGOXXX10.1177/2158244015611712SAGE OpenMcChesney 611712research-article2015 Article SAGE Open October-December 2015: 1 –13 Teaching Diversity: The Science You © The Author(s) 2015 DOI: 10.1177/2158244015611712 Need to Know to Explain Why Race Is sgo.sagepub.com Not Biological Kay Young McChesney1 Abstract This article is targeted to faculty teaching race and ethnicity, racism, diversity, and multicultural courses. Many students equate race with skin color. The premise of this article is that to teach students about the social construction of race, teachers must first know enough science to teach students that race is not biological. This article examines the biology of race by showing how advances in DNA sequencing led to genetics research that supports arguments that race is not biological. DNA comparisons show that all human populations living today are one species that came from Africa. The article explains the migration of humans out of Africa about 60,000 years ago and how they populated Australia, then Asia, Europe, and the Americas. The article shows how recent research maps the timing of the migration and admixture of specific population groups into Europe and India. The article shows how a mutation in one nucleotide can result in a trait like blue eyes, or Hemoglobin S (which confers resistance to malaria), which can be subject to evolution through natural selection. DNA comparisons show how natural selection shaped the genetics of human skin color to adapt to less UV light in the northern latitudes of Europe and Asia. The article shows that there is no relation between skin color or other “racial” characteristics and complex traits like intelligence. -
The Genetics of Human Skin and Hair Pigmentation
GG20CH03_Pavan ARjats.cls July 31, 2019 17:4 Annual Review of Genomics and Human Genetics The Genetics of Human Skin and Hair Pigmentation William J. Pavan1 and Richard A. Sturm2 1Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA; email: [email protected] 2Dermatology Research Centre, The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, Queensland 4102, Australia; email: [email protected] Annu. Rev. Genom. Hum. Genet. 2019. 20:41–72 Keywords First published as a Review in Advance on melanocyte, melanogenesis, melanin pigmentation, skin color, hair color, May 17, 2019 genome-wide association study, GWAS The Annual Review of Genomics and Human Genetics is online at genom.annualreviews.org Abstract https://doi.org/10.1146/annurev-genom-083118- Human skin and hair color are visible traits that can vary dramatically Access provided by University of Washington on 09/02/19. For personal use only. 015230 within and across ethnic populations. The genetic makeup of these traits— Annu. Rev. Genom. Hum. Genet. 2019.20:41-72. Downloaded from www.annualreviews.org Copyright © 2019 by Annual Reviews. including polymorphisms in the enzymes and signaling proteins involved in All rights reserved melanogenesis, and the vital role of ion transport mechanisms operating dur- ing the maturation and distribution of the melanosome—has provided new insights into the regulation of pigmentation. A large number of novel loci involved in the process have been recently discovered through four large- scale genome-wide association studies in Europeans, two large genetic stud- ies of skin color in Africans, one study in Latin Americans, and functional testing in animal models. -
Genetic Determinants of Skin Color, Aging, and Cancer Genetische Determinanten Van Huidskleur, Huidveroudering En Huidkanker
Genetic Determinants of Skin Color, Aging, and Cancer Genetische determinanten van huidskleur, huidveroudering en huidkanker Leonie Cornelieke Jacobs Layout and printing: Optima Grafische Communicatie, Rotterdam, The Netherlands Cover design: Annette van Driel - Kluit © Leonie Jacobs, 2015 All rights reserved. No part of this thesis may be reproduced, stored in a retrieval system or transmitted in any form or by any means, without prior written permission of the author or, when appropriate, of the publishers of the publications. ISBN: 978-94-6169-708-0 Genetic Determinants of Skin Color, Aging, and Cancer Genetische determinanten van huidskleur, huidveroudering en huidkanker Proefschrift Ter verkrijging van de graad van doctor aan de Erasmus Universiteit Rotterdam op gezag van rector magnificus Prof. dr. H.A.P. Pols en volgens besluit van het College voor Promoties. De openbare verdediging zal plaatsvinden op vrijdag 11 september 2015 om 11:30 uur door Leonie Cornelieke Jacobs geboren te Rotterdam PROMOTIECOMMISSIE Promotoren: Prof. dr. T.E.C. Nijsten Prof. dr. M. Kayser Overige leden: Prof. dr. H.A.M. Neumann Prof. dr. A.G. Uitterlinden Prof. dr. C.M. van Duijn Copromotor: dr. F. Liu COntents Chapter 1 General introduction 7 PART I SKIn COLOR Chapter 2 Perceived skin colour seems a swift, valid and reliable measurement. 29 Br J Dermatol. 2015 May 4; [Epub ahead of print]. Chapter 3 Comprehensive candidate gene study highlights UGT1A and BNC2 37 as new genes determining continuous skin color variation in Europeans. Hum Genet. 2013 Feb; 132(2): 147-58. Chapter 4 Genetics of skin color variation in Europeans: genome-wide association 59 studies with functional follow-up.