DOCSLIB.ORG

Intracerebral Hemorrhage

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Intracerebral Hemorrhage This page intentionally left blank Intracerebral Hemorrhage Intracerebral Hemorrhage Edited by J. R. Carhuapoma Johns Hopkins University Hospital, Baltimore, MD, USA S. A. Mayer Columbia University Medical Center, New York, NY, USA D. F. Hanley Johns Hopkins University Hospital, Baltimore, MD, USA CAMBRIDGE UNIVERSITY PRESS Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo, Delhi, Dubai, Tokyo Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK Published in the United States of America by Cambridge University Press, New York www.cambridge.org Information on this title: www.cambridge.org/9780521873314 © J. R. Carhuapoma, S. A. Mayer, and D. F. Hanley 2010 This publication is in copyright. Subject to statutory exception and to the provision of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published in print format 2009 ISBN-13 978-0-511-69131-7 eBook (NetLibrary) ISBN-13 978-0-521-87331-4 Hardback Cambridge University Press has no responsibility for the persistence or accuracy of urls for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Every effort has been made in preparing this publication to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors, and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors, and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this publication. Readers are strongly advised to pay careful attention to information provided by the manufacturer if any drugs or equipment that they plan to use. To my son Ethan and my family for their unconditional support JRC To Catherine, Philip and Elizabeth SAM To my wife and family who have supported my career DFH v Contents List of contributors ix Foreword by Thomas Brott xii Section 1 – Epidemiology Section 4 – Diagnostic investigations 1. The epidemiology of intracerebral 9. Computerized tomography and hemorrhage 1 CT angiography in intracerebral Matthew L. Flaherty, Daniel Woo, and Joseph hemorrhage 121 P. Broderick Rush H. Chewning and Kieran P. Murphy 10. MRI of intracerebral hemorrhage 125 Section 2 – Etiology of non-traumatic Ken Butcher and Stephen M. Davis intracerebral hemorrhage 11. Cerebral angiography 139 2. Acute hypertensive response in intracerebral Rush H. Chewning and Kieran P. Murphy hemorrhage 17 12. Laboratory and other ancillary Ameer E. Hassan, Haralabos Zacharatos, testing in intracerebral and Adnan I. Qureshi hemorrhage: an algorithmic 3. Etiology of tumor-related intracranial approach 149 hemorrhage 31 Michael Chen and Louis R. Caplan Andreas F. Hottinger and Lisa M. DeAngelis 4. Cerebral amyloid angiopathy 41 – Steven M. Greenberg Section 5 Management and critical care 5. Coagulopathy-related intracerebral hemorrhage 58 13. Medical management of Hagen B. Huttner and Thorsten Steiner intracerebral hemorrhage 159 Neeraj S. Naval, Paul A. Nyquist, 6. Vascular malformations of the brain 71 and J. Ricardo Carhuapoma Christian Stapf and J. P. Mohr 7. Cerebral venous thrombosis and intracerebral 14. Surgical management of hemorrhage 84 intracerebral hemorrhage 165 Isabelle Crassard and Marie-Germaine Bousser A. David Mendelow 15. Future therapy in intracerebral hemorrhage and intraventricular Section 3 – Clinical presentation hemorrhage: aspiration and 8. Clinical presentation of intracerebral thrombolysis 176 hemorrhage 101 Paul A. Nyquist, Neeraj S. Naval, Carlos S. Kase and J. Ricardo Carhuapoma vii Contents Section 6 – Prognosis and outcome 19. Cytoprotection strategies for experimental intracerebral hemorrhage 217 16. Mathematical models of intracerebral Crystal MacLellan, James Peeling, and Frederick hemorrhage and intraventricular Colbourne hemorrhage outcomes prediction: their comparison, advantages, and limitations 187 Section 8 – Advances in pathogenesis Stanley Tuhrim and treatment of intracerebral hemorrhage: clinical Section 7 – Advances in 20. Natural history of perihematomal brain pathogenesis and treatment edema 229 of intracerebral hemorrhage: Manuel Rodríguez-Yáñez, Antoni Dávalos, and experimental José Castillo 21. Hemostatic therapy for intracerebral 17. Animal models and experimental hemorrhage 238 treatments of intracerebral Wendy C. Ziai and Stephan A. Mayer hemorrhage 193 Kenneth R. Wagner and Mario Zuccarello 18. Thrombin and secondary brain damage following intracerebral hemorrhage 206 Index 254 Guohua Xi, Richard F. Keep, and Julian T. Hoff Color plate section between pp. 158 and 159. viii Contributors Marie-Germaine Bousser MD Frederick Colbourne PhD Department of Neurology, Department of Psychology, Lariboisière Hospital, Paris, France University of Alberta, Edmonton, Alberta, Canada Joseph P. Broderick MD Department of Neurology, Isabelle Crassard MD University of Cincinnati, Department of Neurology, Cincinnati, OH, USA Lariboisière Hospital, Paris, France Ken Butcher MD PhD FRCPC Antoni Dávalos MD PhD Division of Neurology, Department of Neurosciences, University of Alberta, Hospital Germans Trias i Pujol, Edmonton, Alberta, Canada Barcelona, Spain Louis R. Caplan MD Stephen M. Davis MD FRACP Department of Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Royal Melbourne Hospital, Boston, MA, USA Melbourne, Victoria, Australia Lisa M. DeAngelis MD J. Ricardo Carhuapoma MD FAHA Department of Neurology, Departments of Neurology, Neurosurgery, Memorial Sloan-Kettering Cancer Center, and Anesthesiology & Critical Care Medicine, New York, NY, USA Division of Neurosciences Critical Care, The Johns Hopkins Medical Institutions, Matthew L. Flaherty MD Baltimore, MD, USA Department of Neurology, University of Cincinnati, Cincinnati, OH, USA José Castillo MD PhD Department of Neurology, Steven M. Greenberg MD PhD Hospital Clínico Universitario, Neurology Stroke Service, University of Santiago de Compostela, Massachusetts General Hospital, Santiago de Compostela, Spain Boston, MA, USA Michael Chen MD Daniel F. Hanley MD Departments of Neurology and Radiology, Departments of Neurology, Neurosurgery, Rush University Medical Center, and Anesthesiology & Critical Care Medicine, Chicago, IL, USA Division of Brain Injury Outcomes Research, The Johns Hopkins Hospital, Rush H. Chewning BA Baltimore, MD, USA Department of Radiology, The Johns Hopkins Hospital, Ameer E. Hassan DO ix Baltimore, MD, USA Department of Neurology, List of contributors University of Minnesota Medical Center, Neeraj S. Naval MD Minneapolis, MN, USA Department of Neurology, Neurosurgery, and Anesthesia Critical Care Medicine, Julian T. Hoff MD Neurosciences Critical Care Division, Formerly Department of Neurosurgery, Oregon Health Sciences University School of Medicine, University of Michigan, Oregon, USA Ann Arbor, MI, USA Paul A. Nyquist MD Andreas F. Hottinger Department of Neurology, Neurosurgery, Department of Neurology, and Anesthesiology & Critical Care Medicine, Memorial Sloan-Kettering Cancer Center, Division of Neurosciences Critical Care, New York, NY, USA Johns Hopkins Medical Institutions, Baltimore, MD, USA Hagen B. Huttner MD Department of Neurology, James Peeling PhD University of Heidelberg, Heidelberg, Department of Chemistry, Germany University of Winnipeg, Winnipeg, Manitoba, Canada Carlos S. Kase MD Department of Neurology, Adnan I. Qureshi MD Boston Medical Center, Boston, MA, USA Department of Neurology, University of Minnesota Medical Center, Richard F. Keep PhD Minneapolis, MN, USA Department of Neurosurgery, University of Michigan, Manuel Rodriguez-Yáñez MD Ann Arbor, MI, USA Department of Neurology, Hospital Clínico Universitario, Crystal MacLellan PhD University of Santiago de Compostela, Department of Psychology, Santiago de Compostela, Spain University of Alberta, Edmonton, Alberta, Canada Christian Stapf MD Stephan A. Mayer MD Department of Neurology, Department of Neurology, Lariboisière Hospital, Paris, France Columbia University Medical Center, Thorsten Steiner MD New York, NY, USA Department of Neurology, A. David Mendelow PhD FRCSEd University of Heidelberg, Heidelberg, Germany Department of Neurosurgery, Stanley Tuhrim MD Newcastle General Hospital, Department of Neurology, Newcastle upon Tyne, UK Mt Sinai Medical Center, New York, NY, USA J. P. Mohr MD PhD Kenneth R. Wagner PhD Department of Neurology, Department of Neurology, Columbia University Medical Center, University of Cincinnati, Cincinnati, New York, NY, USA OH, USA Kieran P. Murphy MD Daniel Woo MD Department of Radiology, Department of Neurology, The Johns Hopkins Hospital, University of Cincinnati, Cincinnati, x Baltimore, MD, USA OH, USA List of contributors Guohua Xi MD Wendy C. Ziai MD Department of Neurosurgery, Department of Neurology, University of Michigan, The Johns Hopkins Hospital, Ann Arbor, MI, USA Baltimore, MD, USA Haralabos Zacharatos DO Mario Zuccarello MD Department of Neurology, Department of Neurology, University of Minnesota Medical Center, University of Cincinnati,
Load more

Recommended publications
  • Health Care Reform and Stroke Prognosis in Low-Income Chinese
    © 2021 The Author(s) Cite as: Liu J, Lin Q, Gao Y, Zhang Y, Qi D, Wang C, Tu J Wang Y, Ning X, Wang J. JoGH © 2021 ISGH Health care reform and stroke prognosis in low-income Chinese populations from 1992 to 2018. J Glob Health 2021;11:08002. Health care reform and stroke prognosis in low-income Chinese PAPERS VIEWPOINTS populations from 1992 to 2018 1,2,3 1,2,3 4 5 Jie Liu *, Qiuxing Lin *, Ying Gao *, Xinxin Zhang , Background To assess the impact of the health care Dongwang Qi6, Conglin Wang7, Jun Tu1,2,3, Yaogang reform on stroke prognoses among low-income Chi- Wang8, Xianjia Ning1,2,3, Jinghua Wang1,2,3 nese residents. Methods Stroke events and all-cause deaths were reg- 1 Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China istered during 1992-2018 in Tianjin, China. Trends 2 Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, China in stroke management and prognoses were compared 3 Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury during the study periods1992-2008 and 2009-2018. Neuro-repair and Regeneration in Central Nervous System, Ministry of Results A total of 1462 patients were diagnosed with Education and Tianjin City, Tianjin, China 4 Health Management Centre, Tianjin Medical University General Hospital, first-ever stroke during the study periods. For patients Tianjin, China aged ≥45 years, the rates of neuroimaging-based diag- 5 Department of Endocrinology and Metabolism, Tianjin Medical noses and hospitalization were greater in 2009-2018 University General Hospital, Tianjin, China than in 1992-2008, regardless of patient sex or stroke 6 Department of Neurology, Yiwu Central Hospital, Yiwu, Zhejiang type.
    [Show full text]
  • Neurological Manifestations of COVID-19: a Systematic Review
    Nepal et al. Critical Care (2020) 24:421 https://doi.org/10.1186/s13054-020-03121-z RESEARCH Open Access Neurological manifestations of COVID-19: a systematic review Gaurav Nepal1 , Jessica Holly Rehrig2, Gentle Sunder Shrestha3*, Yow Ka Shing4, Jayant Kumar Yadav1, Rajeev Ojha5, Gaurab Pokhrel6, Zhi Lan Tu7 and Dong Ya Huang8 Abstract Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the global spread of coronavirus disease (COVID-19). Our understanding of the impact this virus has on the nervous system is limited. Our review aims to inform and improve decision-making among the physicians treating COVID-19 by presenting a systematic analysis of the neurological manifestations experienced within these patients. Methods: Any study, released prior to May 20, 2020, that reported neurological manifestations in patients infected by SARS-CoV-2 was systematically reviewed using the PRISMA (Preferred Reporting Items for Systemic review and Meta-Analysis) statement. Results: Our systematic review included data from 37 articles: twelve retrospective studies, two prospective studies, and the rest case reports/series. The most commonly reported neurological manifestations of COVID-19 were myalgia, headache, altered sensorium, hyposmia, and hypogeusia. Uncommonly, COVID-19 can also present with central nervous system manifestations such as ischemic stroke, intracerebral hemorrhage, encephalo-myelitis, and acute myelitis, peripheral nervous manifestations such as Guillain-Barré syndrome and Bell’s palsy, and skeletal muscle manifestations such as rhabdomyolysis. Conclusion: While COVID-19 typically presents as a self-limiting respiratory disease, it has been reported in up to 20% of patients to progress to severe illness with multi-organ involvement.
    [Show full text]
  • Trend of Declining Stroke Mortality in China: Reasons and Analysis
    Open Access Original article Stroke Vasc Neurol: first published as 10.1136/svn-2017-000098 on 20 June 2017. Downloaded from Trend of declining stroke mortality in China: reasons and analysis Wenzhi Wang,1,2 David Wang,3 Hongmei Liu,1,2 Haixin Sun,1,2 Bin Jiang,1,2 Xiaojuan Ru,1,2 Dongling Sun,1,2 Zhenghong Chen,1,2 Yongjun Wang4 To cite: Wang W, Wang D, Liu H, ABSTRACT 2005, stroke was found to be the first leading et al. Trend of declining stroke Introduction There is a downward trend of stroke-related cause of death in the third national survey mortality in China: reasons and mortality in the USA. By reviewing all published articles 5 analysis. on all causes of death. Then, what was the Stroke and Vascular on stroke mortality in China, we analysed its trend and Neurology 2017;0: e000098. trend in stroke mortality in China over the doi:10.1136/svn-2017-000098 possible factors that have influenced the trend. past 30 years? Was it trending up or down? Methods Both English and Chinese literatures were By reviewing all published articles on stroke searched on the mortality of stroke or cerebrovascular mortality in China, we analysed its trend and Received 24 May 2017 diseases in China. Potential papers related to this topic Accepted 8 June 2017 were identified from PubMed, Medline, Embase, Cochrane possible underlying factors that have influ- Library, Wanfang Database, SINOMED and China National enced the trend. Knowledge Infrastructure databases. Results Comparing the results from the most recent METHODS population-based epidemiological survey and databank Both English and Chinese literatures were from the national Center for Disease Control and Prevention, the age-adjusted stroke mortality rate has searched on the mortality of stroke or cere- shown a downward trend among both urban and rural brovascular diseases in China.
    [Show full text]
  • Mission Thrombectomy 2020+ (MT2020+)
    Mission Thrombectomy 2020+ Global Executive Committee (MT2020+ GEC), October, 24th, 2020 1 1 Mission Thrombectomy 2020+ (MT2020+) Stroke is the leading cause of neurological disa- MT by itself, or in combination with pharmaco- bility and second leading cause of death world- logical thrombolysis when indicated, is an over- wide. Approximately 85% of all strokes are due whelmingly effective and safe treatment for se- to sudden blockage in or occlusion of an artery lected LVO stroke, when performed rapidly in the brain and are called acute ischemic within the first 24 hours after symptoms begin. strokes (AIS). Strokes due to occlusion of large MT removes the blockage in the large vessel arteries in the brain comprise around 1/3 of all causing the stroke and restores blood flow to AIS and are commonly referred to as large ves- the brain tissue, and thereby saves portions of sel occlusion (LVO) strokes. LVO strokes result the brain that have not been irreversibly dam- in a disproportionate health burden in the aged from lack of oxygen, leading to restora- population, causing three-fifths of dependency tion of neurological function. This treatment has and more than nine-tenths of mortality after also been shown to be cost-effective despite AIS. Mission Thrombectomy 2020+ (MT2020+) being resource intensive across different income is a global non-profit campaign and multi- level countries. stakeholder alliance initiated by the Society of Vascular and Interventional Neurology (SVIN) in The overarching goal of MT2020+ is to 2016, to accelerate access to emergency me- accelerate the regional growth of thrombectomy chanical thrombectomy (MT) surgery for treat- procedure capacity and systems to enable ment of LVO stroke worldwide.
    [Show full text]
  • The Clinical Characteristics and Prognosis of COVID-19 Patients with Cerebral Stroke
    The clinical characteristics and prognosis of COVID- 19 patients with cerebral strokea retrospective cohort study Xiaolong Yao Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Shengwen Liu Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Junwen Wang Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Kai Zhao Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Xiaobing Long Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Xuejun He Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Huicong Kang Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Yiping Yang Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Xiaopeng Ma Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Pengjie Yue Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Kai Shu Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Zhouping Tang Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Ting Lei Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Jihong Liu ( [email protected] ) Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wei Wang ( [email protected] ) Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Huaqiu Zhang ( [email protected] ) Page 1/17 Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Research Article Keywords: COVID-19, SARS-CoV-2, stroke, clinical characteristics, prognosis Posted Date: June 23rd, 2020 DOI: https://doi.org/10.21203/rs.3.rs-37573/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License.
    [Show full text]
  • Delayed Stroke Treatment During COVID-19 Pandemic in China
    medRxiv preprint doi: https://doi.org/10.1101/2020.11.17.20228122; this version posted November 18, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Title Delayed Stroke Treatment during COVID-19 Pandemic in China Running Head COVID-19 Pandemic and Stroke Authors and Affiliations Shiyuan Gu, MD1,2; Zhengze Dai, MD3; Huachao Shen, MD4; Yongjie Bai, MD5; Xiaohao Zhang, MD6; Xinfeng Liu, MD1,6; Gelin Xu, MD, PhD1,6 1 Department of Neurology, Jinling Clinical College of Nanjing Medical University, Nanjing 210002, China 2 Department of Neurology, The Affiliated Yixing Hospital of Jiangsu University, Yixing, 214200, China 3 Department of Neurology, The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing Pukou Hospital, Nanjing 210031, China 4 Department of Neurology, BenQ Medical Center, Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, 210031, China 5 Department of Neurology, First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China 6 Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China Address for Correspondence and Reprints Professor Gelin Xu, Department of Neurology, Jinling Clinical College of Nanjing Medical University, Nanjing 210002, China. Tel: +86-25-84801861; Fax: +86-25-84805169. Email: [email protected]. 0 NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice. medRxiv preprint doi: https://doi.org/10.1101/2020.11.17.20228122; this version posted November 18, 2020.
    [Show full text]
  • Current Endovascular Strategies for Posterior Circulation Large Vessel
    J NeuroIntervent Surg: first published as 10.1136/neurintsurg-2019-014873 on 18 May 2019. Downloaded from Standards Current endovascular strategies for posterior circulation large vessel occlusion stroke: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee Yasha Kayan, 1 Philip M Meyers,2 Charles J Prestigiacomo,3 Peter Kan,4 Justin F Fraser, 5 on Behalf of the Society of NeuroInterventional Surgery 1Neurointerventional Radiology, ABSTRact on revascularization of the occlusion.13 14 Lindsberg Abbott Northwestern Hospital, Background The aim of this publication is to provide et al report good clinical outcomes with recanali- Minneapolis, Minnesota, USA 15 2 zation in 38% versus 2% without recanalization. Neurointerventional Surgery, a detailed update on the diagnosis, treatment, and Columbia Presbyterian Hospital, endovascular techniques for posterior circulation From the Helsinki Stroke Thrombolysis Registry, New York City, New York, USA emergent large vessel occlusion (pc-ELVO). Sairanen et al report good clinical outcomes with 3Neurological Surgery, University Methods We performed a review of the literature to recanalization in 86% versus 14% without reca- of Cincinnati, Cincinnati, Ohio, specifically evaluate this disease and its treatments. nalization.7 Similarly, Kumar et al report 1.5 times USA 4Department of Neurosurgery, Results Data were analyzed, and recommendations decreased dependency and two times decreased 14 Baylor College of Medicine, were reported based on the strength of the published mortality with recanalization than without it. Houston, Texas, USA evidence and expert consensus. With these data in mind, the aims of this docu- 5 Neurological Surgery, University Conclusion While many questions about pc-ELVO ment include: (1) to review data on the natural of Kentucky, Lexington, history and outcomes from pc-ELVO and (2) Kentucky, USA remain to be studied, there is evidence to support particular practices in its evaluation and treatment.
    [Show full text]
  • By Farrah J. Mateen a Dissertation Submitted to Johns Hopkins University in Conformity with the Requirements for the Degree Of
    EMERGING, NON-HEREDITARY RISK FACTORS FOR STROKE: THREE STUDIES by Farrah J. Mateen A dissertation submitted to Johns Hopkins University in conformity with the requirements for the degree of Doctor of Philosophy. Baltimore, Maryland April 2014 Abstract Stroke is a leading cause of death and disability globally. The vast majority of all strokes occur in low- and middle-income countries, where data are least available to guide clinical decision-making and health policy. Many strokes are preventable, and established risk factors for stroke are well-known in the scientific literature. However, some risk factors may be less well-recognized but have a particular influence in specific subpopulations. Here, three risk factors for strokes are studied in three separate populations. Fatal stroke in Bangladesh is studied with an emphasis on the potential role of betel nut as a stroke risk factor. Human Immunodeficiency Virus infection and its relationship to stroke, including use of the predictive Framingham Risk Score, is studied in men who have sex with men in the United States. Finally, groundwater arsenic exposure in American Indians is analyzed as a risk factor for carotid artery disease endpoints which are subclinical measurement that directly relate to stroke risk. The relationship between these risk factors and stroke, including their implications for younger-onset stroke, stroke prevention, and advocacy for vascular diseases on the global health agenda are emphasized. Thesis Defense Committee Robert Black, MD, MPH, Department of International Health, Thesis Advisor Ciprian Crainiceanu, PhD, Department of Biostatistics, Committee Chair Ana Navas-Acien, MD, PhD, Department of Environmental Sciences David Sack, MD, Department of International Health ii List of Tables Table 1.
    [Show full text]
  • Assessing the Health Effects of Extreme Temperatures and Development of Adaptation Strategies to Climate Change in the Asia-Pacific Region
    Final Technical Report CRRP2016-10MY-Huang Assessing the health effects of extreme temperatures and development of adaptation strategies to climate change in the Asia-Pacific region The following collaborators worked on this project: 1. Cunrui Huang, Sun Yat-sen University, China, [email protected] 2. Dung Phung, Griffith University, Australia, [email protected] 3. Zhiwei Xu, Queensland University of Technology, Australia, [email protected] 4. Wenjun Ma, Guangdong Provincial Center for Disease Control and Prevention, China, [email protected] 5. Benjawan Tawatsupa, Department of Health, Ministry of Public Health, Thailand, [email protected] 6. Mohammad Sohel Shomik, International Centre for Diarrhoeal Disease Research (ICDDR, B), Bangladesh, [email protected] 7. Do Manh Cuong, Ministry of Health of Vietnam, Vietnam, [email protected] 8. Cordia Chu, Griffith University, Australia, [email protected] 9. Adrian Barnett, Queensland University of Technology, Australia, [email protected] Copyright © 2019 Asia-Pacific Network for Global Change Research APN seeks to maximise discoverability and use of its knowledge and information. All publications are made available through its online repository “APN E-Lib” (www.apn-gcr.org/resources/). Unless otherwise indicated, APN publications may be copied, downloaded and printed for private study, research and teaching purposes, or for use in non-commercial products or services. Appropriate acknowledgement of APN as the source and copyright holder must be given, while APN’s endorsement of users’ views, products or services must not be implied in any way. For reuse requests: http://www.apn-gcr.org/?p=10807 Table of Content Project Overview ...............................................................................................................
    [Show full text]
  • Health Care Utilization for Patients with Stroke: a 3-Year Cross-Sectional Study of China’S Two Urban Health Insurance Schemes Across Four Cities
    Health care utilization for patients with stroke: A 3-year cross-sectional study of China’s two urban health insurance schemes across four cities Yong Yang Beijing University of Chinese Medicine Stephen Nicholas Australian National Institute of Management and Commerce Shuo Li Beijing University of Chinese Medicine Zhengwei Huang Beijing University of Chinese Medicine Xiaoping Chen Beijing University of Chinese Medicine Yong Ma China Health Insurance Research Association Xuefeng Shi ( [email protected] ) Research article Keywords: Stroke, Healthcare utilization, Health insurance, Cost of illness Posted Date: June 22nd, 2020 DOI: https://doi.org/10.21203/rs.3.rs-37086/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Version of Record: A version of this preprint was published on March 18th, 2021. See the published version at https://doi.org/10.1186/s12889-021-10456-x. Page 1/13 Abstract Background Stroke is a devastating disease and a major cause of death and disability worldwide. We evaluated differences in stroke patients’ health care utilization by insurance type across four cities in China. Methods The data were a 5% random sampling from claims data of China Urban Employees’ Basic Medical Insurance (UEBMI) and Urban Residents’ Basic Medical Insurance (URBMI) from 2014 to 2016. The descriptive analyze and interaction actions were mainly conducted. Results We found that differences in healthcare utilization and medical expenses varied more across the four cities, Beijing, Shanghai, Tianjin, and Chongqing, than they did between the UEBMI and URBMI scheme. On average, UEBMI patients had a signicantly larger number of outpatient (4.3) and inpatient (1.4) visits per year than the URBMI group (2.0 outpatient and 1.1 inpatient visits per year).
    [Show full text]
  • Estimating the Future Burden of Cardiovascular Disease and the Value of Lipid and Blood Pressure Control Therapies in China Warren Stevens1*, Desi Peneva2, Jim Z
    Stevens et al. BMC Health Services Research (2016) 16:175 DOI 10.1186/s12913-016-1420-8 RESEARCH ARTICLE Open Access Estimating the future burden of cardiovascular disease and the value of lipid and blood pressure control therapies in China Warren Stevens1*, Desi Peneva2, Jim Z. Li3, Larry Z. Liu4, Gordon Liu5, Runlin Gao6 and Darius N. Lakdawalla7 Abstract Background: Lifestyle and dietary changes reflect an ongoing epidemiological transition in China, with cardiovascular disease (CVD) playing an ever-increasing role in China’s disease burden. This study assessed the burden of CVD and the potential value of lipid and blood pressure control strategies in China. Methods: We estimated the likely burden of CVD between 2016 and 2030 and how expanded use of lipid lowering and blood pressure control medication would impact that burden in the next 15 years. Accounting for the costs of drug use, we assessed the net social value of a policy that expands the utilization of lipid and blood pressure lowering therapies in China. Results: Rises in prevalence of CVD risk and population aging would likely increase the incidence of acute myocardial infarctions (AMIs) by 75 million and strokes by 118 million, while the number of CVD deaths would rise by 39 million in total between 2016 and 2030. Universal treatment of hypertension and dyslipidemia patients with lipid and blood pressure lowering therapies could avert between 10 and 20 million AMIs, between 8 and 30 million strokes, and between 3 and 10 million CVD deaths during the 2016–2030 period, producing a positive social value net of health care costs as high as $932 billion.
    [Show full text]
  • Beijing Tiantan Comprehensive Stroke Center Directed by Professor Wang, Yongjun
    Journal of Neurology & Stroke Beijing Tiantan Comprehensive Stroke Center Directed by Professor Wang, Yongjun News News China, as one of the biggest developing country, is having more and more impact in the World. That is not only in global Volume 3 Issue 6- 2015 economy, global warming and global pollution, but also in the global medical research. Medical research contributes to, human health, aims to reduce morbidity and mortality, improve outcome Director of ACURE Biotechnology, Inc., Ellicott City, USA of diseases and maintain a basic independent personal quality of *Corresponding author: Xin Wang, ACURE life. Stroke is the fourth deadly disease. Moreover, impairments Biotechnology, Inc., Ellicott City, MD 21043, USA, and disabilities left after stroke onset cost a lot of fortunes Email: and resources of society, severely affect daily life. Here, I try to Received: December 21, 2015 | Published: December 21, 2015 stroke in Beijing Tiantan comprehensive stroke center directed bybriefly Professor introduce Wang, milestones Yongjun thathad themade medical in this professionals decade based of and professional education since then. Tiantan Stroke Unit on his reorganized collection of editorial of Chinese Journal of has been supported by the Chinese government and accepted Stroke--In My Mind [1]. Neurologist Professor Wang, Yongjun is funding for missions of “Eleventh-Five” and “Twelfth-Five” my dearest mentor when I specialized in Neurology as a clinical national science and technology supporting programs. In 2010, professional in Beijing, China (Figure 1). Tiantan Comprehensive Stroke center is founded to match the rapidly developing needs of national and international exchange of medical research in cerebrovascular disease. We have to introduce the history of Beijing Tiantan Hospital that the accomplishment of the professional team of Stroke leans on.
    [Show full text]