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SMB Newsletter Volume 21 #2 - May 2008

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SMB Newsletter Volume 21 #2 - May 2008 SMB Newsletter Volume 21 #2 - May 2008 2008 SMB Election Results Society for Mathematical Congratulations to the newly elected President-elect and Board Members! Biology Annual Meeting President-elect: Michael Mackey July 30-August 2, 2008 http://www.smb.org/meetings/annual.shtml hosted by the Centre for Mathematical Medicine, Fields Institute held at University of Toronto, Medical Sciences Bldg Local Organizing Committee M. Kohandel (Waterloo), I. Pressman (Carleton), F. Skinner (Toronto Western Research Inst.), S. Sivaloganathan - Chair (Waterloo), New Board Members: Hongmei Zhu (York) Contributed talk proposals will be accepted until May 15, 2008. Poster proposals will be accepted until July 15, 2008. Plenary speakers include M. Golubitsky (Houston), M. Knothe Tate (Case Western), N. Komarova (UC Irvine), H. Levine (UC San Diego), M. Lewis (Alberta), L. Mahadevan (Harvard), T. Secomb (Arizona) and Y. Zhou (China). Mary Myerscough Renee Fister Inside this Issue: Janet L. Anderson Prize...........................................3 My Career in Mathematical Biology - A Personal Journey by Philip Maini..........................................6 Highlights in Mathematical Biology...............4-5,8-9 Positions Available............................................10-12 Santiago Schnell 1 new improved format of the SMB Newsletter; she deserves our thanks. Dear SMB Members: On a personal side I am happy to inform you that, I am looking forward to meeting many of you at after seven years, I will step down this September the annual SMB conference in Toronto, July 30 - as the Director of the Mathematical Biosciences August 2. The plenary speakers represent a broad Institute (MBI). Marty Golubitsky will become the range of mathematical biology and the themes of new Director. Marty is a world leader in dynamical the conference, like in previous years, will cover all systems; he served as the President of SIAM, and areas of biology where mathematical modeling and he is one of the plenary speakers in the Toronto simulation are actively pursued. conference. His wife, Barbara Keyfitz, will join the mathematics department at Ohio State University. As you must have noticed, the SMB Newsletter now She is currently serving the last year as Director of appears in a very nice format. Content wise, it now the Fields Institute in Toronto; she is organizing a includes autobiographical profiles of career paths of program on mathematical and quantitative oncology mathematical biologists. We hope these profiles will at the Fields Institute following the SMB conference. inspire young people to pursue research and careers in biomathematics. The SMB Newsletter also now I wish you all a great Spring and I am looking includes “nuggets” or “highlights;” these are short forward to meeting you in Toronto. articles that describe a success story in mathematical biology. I encourage any one who wishes to Sincerely, contribute a personal success story to send this to me in the form of a “nugget,” and, if appropriate, we Avner Friedman shall publish it in the Newsletter. SMB President The World Outreach Committee, newly formed last autumn, has been very active. In January 2008, Aziz Yakubu (the committee’s chair) and I participated in a mathematical biology conference in Marrakech, where we witnessed the official formation of the African Society of Biomathematics. Both Aziz and I are serving on the liaison committee of this newly formed society. There are current discussions among the members of the World Outreach Committee on extending activities to other countries. The Springer publication of the Bulletin of Mathematical Biology has been proceeding very smoothly, thanks to the hard work of Philip Maini, the Editor, and the excellent coordination with Achi Dosanjh from Springer. Renewal of the annual SMB membership is now available online. This will make it much easier for you to renew your membership, as well as for those who wish to become new members. Holly Gaff has done a great job in putting the membership renewal procedure online, as well as in setting up the 2 and/or computational biology exhibited in a presentation by an undergraduate student,” and was given for the first time at the San Jose Mathfest. We are writing now to ask if you would like to contribute to this fund. We hope that, with your assistance, we will be able to offer two prizes each year, one to a Pi Mu Epsilon Janet L. Anderson speaker and one to an MAA student speaker, as is Prize customary for the other student prizes. We are grateful for any contribution you may care to make. Checks should be directed to: The Janet L. Andersen Prize Fund, c/o Lisa Kolbe, Development The MAA’s special interest group in mathematical and Manager, The Mathematical Association of America, computational biology (BioSIGMAA) has recently 1529 18th Street NW, Washington, DC 20036 established an award in honor and memory of our late colleague, Janet L. Andersen. Until her untimely death in November 2005, Janet Andersen was Professor of Mathematics at Hope Upcoming Meetings College in Holland, Michigan. She joined the Hope faculty in 1991 after completing her master’s and Mathematical Tools for Multi-Scale Biological doctoral work in algebraic geometry at the University Processes of Minnesota. Call for abstracts for the International Conference: Janet was a beloved and dedicated teacher of Mathematical Tools for Multi-Scale Biological mathematics and served the profession in myriad Processes at Montana State University, Bozeman, MT, ways, from her role as director of the Pew MidStates June 4 to June 6, 2008. Science and Mathematics Consortium to her service as chair of the MAA’s committee on the teaching of There is limited financial support for graduate students undergraduate mathematics. and postdoctoral researchers. For more information, see: http://www.math.ufl.edu/~deleenhe/montana/index.html Half a dozen years ago or so Janet became actively Confluence of Biology and Mathematics in interested in mathematical biology, and was the Commonwealth of Kentucky Principal Investigator for an NSF grant to develop a The Biology and Mathematics in Population Studies mathematical biology course, which she then taught (BioMaPS) group at Murray State University, at Hope College several times. In conjunction with invites you, graduate students and especially your that course, she mentored many student undergraduate undergraduate students to attend a workshop entitled research projects. Through activities of the “The Confluence of Biology and Mathematics in BioQUEST curriculum consortium, the Society for the Commonwealth,” May 16-17, 2008. There is no Mathematical Biology and in many other ways, she registration fee. The target deadline for registration was untiring in her efforts to promote the inclusion is Friday, May 2, 2008. This is for us to get an of mathematics in biology education (and vice approximate number for planning. Please send us email versa) and encouraged broad collaboration among if you are interested after this date. There will be funds mathematicians and biologists in both research and available for 30 undergraduate students for housing. teaching. If you need more info, email christopher.mecklin@ murraystate.edu or go to http://campus.murraystate.edu/ The Janet L. Andersen prize is awarded annually at biomaps for the registration form and more information MAA MathFest by “for excellence in mathematical about the workshop. 3 Highlights in Both types of vascular access can have complications that require further treatment or surgery. As a well- Mathematical Biology functioning vascular access is essential for hemodialysis, Mathematical Insights extensive morbidity exists among end-stage renal into Biological Processes disease (ESRD) patients. How long can someone live Submit your story to: [email protected] on dialysis and how well can someone do, depend heavily on the quality of the medical care. The expense The LifeLine: of creating and maintaining vascular access for patients Vascular Access for Hemodialysis on dialysis accounts for a significant portion of any Paula Grajdeanu health care system. In the US alone, more than 20% of patients with ESRD are hospitalized for vascular access Healthy kidneys filter wastes from blood and keep procedures, at an annual cost of 1 billion dollars. body chemicals in balance. When the kidneys fail to perform their functions to full capacity, one cannot live The leading cause of access failure is from loss of long without some form of renal replacement therapy. patency due to venous stenosis (50% narrowing of the One available treatment is hemodialysis, in which the blood vessel), as the result of neointimal hyperplasia patients’ blood is pumped into an artificial kidney where formation either at the site of venous anastomosis or in metabolic waste products diffuse out of the blood, and the downstream vein. It is then of critical importance the cleansed blood is then returned back to the body. to detect access stenosis in a timely manner so that Most people have 3 dialysis sessions every week, each appropriate corrective steps can be undertaken prior session for about 3 to 4 hours. to thrombosis (total occlusion of the blood vessel). However, while the occurrence of stenosis is well recognized, the pathogenesis of it is complex and still not well understood. The process involves a number of growth factors, migration and proliferation of different types of cells, and excessive production of extracellular matrix. The release of growth factors due to oxidative stress
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