PPARGC1B Antibody Cat. No.: 16-896

PPARGC1B Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

A synthetic peptide corresponding to a sequence within amino acids 850-950 of human IMMUNOGEN: PPARGC1B (NP_001166170.1).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) HeLa

2) MCF7

3) mouse brain

PREDICTED MOLECULAR Observed: 113kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

September 30, 2021 1 https://www.prosci-inc.com/ppargc1b-antibody-16-896.html CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: PPARGC1B

ERRL1, PERC, PGC-1(beta), PGC1B, peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-related estrogen receptor alpha coactivator, PPAR-gamma ALTERNATE NAMES: coactivator 1-beta, PPARGC-1-beta, PPARgamma coactivator 1 beta, peroxisome proliferator-activated receptor gamma, coactivator 1 beta

GENE ID: 133522

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non- BACKGROUND: oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 30, 2021 2 https://www.prosci-inc.com/ppargc1b-antibody-16-896.html