Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001190925Cyc: Azoarcus sp. CIB Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

arsenite molybdate ammonium ammonium phosphate phosphate

RS19910 RS10785 CysT FliG RS19485 RS09905 RS14570 RS04215 RS21440 RS18760 RS21255 RS21130 NtrB RS20840 RS03365 TatA MlaE GltK ModC RS11950 RS20375 MscL RS00230 FtsY RS06200 MreD RsxG RsxA RS05930 TrkD RS23790 RS05700 RS19990 RS17250 Amt RS00340 RS05820 RS11390 RS16285 RsxC RS20330 SecE RS11765 RS11825 ArsA ModB RS20380 RS16915 RS22975 RS23045 RS20575 RS17745 RS23520 MotD RS03725 XrtA RS09030 SecD RS09325 RS21615 RS21755 RS10055 FliQ RS19665 RS15510 RS02555 PstB RS05480

arsenite molybdate ammonium ammonium phosphate phosphate

RS02790 RS11330

RS16425 RS13150

Aromatic Compound Biosynthesis Amino Acid Degradation an O 6 - L-alanyl-γ-D- a [bis(guanylyl UDP-N-acetyl- N-acetyl-α- Cofactor, Carrier, and Vitamin Biosynthesis a 2-acyl-1-lyso- an acyl-[acyl- 3-phenyl-2- a [protein]- L(or D)-O- a D-tyrosyl- a D-aspartyl- an L-cysteinyl- cob(II)yrinate a,c- L-isoleucine degradation I L-threonine adenosylcobinamide a purine methylguanine α a lipid II [2Fe-2S] iron-sulfur ubiquinol-8 biosynthesis ubiquinol-8 biosynthesis flavin biosynthesis I (bacteria and plants) superpathway of adenosylcobalamin superpathway of tetrahydrofolate biosynthesis chorismate biosynthesis I Fermentation mixed acid fermentation L-leucine degradation I L-tyrosine degradation I phosphatidylethanolamine oxopropanoate tyr L-cysteine glutamyl-meso-2,6- molybdopterin) cys -D-muramoyl- Tyr asp Cys D-muramoyl- L-selenocysteine diamide biosynthesis I cob(II)yrinate a,c-diamide superpathway of heme b dipyrromethane 3-(4-hydroxyphenyl) degradation I L-arginine degradation L-proline degradation I carrier protein] ribonucleoside phosphoserine [tRNA ] [tRNA ] [tRNA ] RS17310 RS09725 cluster biosynthesis (early decarboxylation) salvage from cobinamide I in DNA diaminopimeloyl- UDP-N-acetyl- cofactor L-alanyl-γ-D- L-alanine(1-) (early cobalt insertion) biosynthesis II (late (late decarboxylation) biosynthesis from glutamate cofactor biosynthesis pyruvate biosynthesis II (AST pathway) bifunctional D-erythrose 5'-triphosphate D-alanine α-D-muramate chaperone]- glutamyl-meso-2,6- cobalt incorporation) all-trans- phosphoenolpyruvate ile penicillin- phosphoserine uroporphyrinogen-III chorismate cob(II)inamide an apo-[hydroxymethylbilane 4-phosphate thr leu tyr pro bifunctional aspartate/ bifunctional L-cysteine diaminopimeloyl- 1,6-anhydro-N- SufS family L-cysteine desulfurase 4-hydroxybenzoate octaprenyl GTP GTP glu 3-deoxy-7- arg binding phosphatase/ D-tyrosyl- D-tyrosyl- aminoacyl-tRNA uroporphyrinogen-III uroporphyrinogen-III synthase]-L-cysteine tyr branched-chain aspartate/ acyl-ACP-- bifunctional tyrosine/aromatic DNA-binding D-alanyl-D-alanine diphosphate glutamate-- phosphoheptulonate branched-chain threonine trifunctional UDP-N- protein homoserine tRNA(Tyr) tRNA(Tyr) hydrolase: acetylmuramyl- cysteine C-methyltransferase: uroporphyrinogen-III chorismate lyase: cob(I)yrinic acid aspartate/ phosphoenolpyruvate pyruvate kinase: pyk amino acid tyrosine/aromatic arginine N- L-arginine phospholipid O- adenosylcobinamide aminotransferase: transcriptional RS03320 FlgK cysteine bifunctional synthase AroG: aroG ammonia- transcriptional acetylmuramate:L- IscS subfamily 2: mrdA phosphotransferase deacylase: deacylase: AzCIB_RS02955 L-alanine desulfurase: C-methyltransferase: AzCIB_RS20910 a,c-diamide GTP tRNA ligase: tyrosine/aromatic carboxylase: amino acid transaminase: succinyltransferase: acyltransferase/ kinase/ AzCIB_RS13945 regulator/O6- cobA desulfurase: 4-hydroxybenzoate a [hydroxymethylbilane pyruvate kinase: pyk lyase, aminotransferase: degradation VI alanyl-gamma-D- ThrH: thrH AzCIB_RS14590 AzCIB_RS14590 amidase sufS cobA all-trans- 3,4-dihydroxy- cyclohydrolase AzCIB_RS07940 3-deoxy-7- aminotransferase: transaminase: AzCIB_RS05285 regulator/proline adenosylcobinamide- cysteine penicillin- D-alanyl-D-alanine aminoacyl-tRNA [+ 2 isozymes] sufS octaprenyltransferase: adenosyltransferase: an L-glutamyl- synthase] ES intermediate AzCIB_RS03925 biosynthetic: AzCIB_RS04495 AzCIB_RS03830 (arginase 2 pathway) long-chain-fatty- aspartate/ methylguanine-DNA AmpD: ampD octaprenyl 2-butanone- 2 phosphoheptulonate AzCIB_RS04495 4-methyl-2- dehydrogenase/L- glutamyl- meso- desulfurase: binding phosphoserine aminoacyl-tRNA aminoacyl-tRNA hydrolase: 4-hydroxybenzoate cobO I FolE2: Glu AzCIB_RS03830 arginine N- acid--ACP ligase: phosphate methyltransferase carboxypeptidase/ precorrin-1 [+ 2 isozymes] [+ 2 isozymes] AzCIB_RS20905 [tRNA ] ilvA oxopentanoate aspartate/ tyrosine/aromatic diaminopimelate precorrin-1 diphosphate 4-phosphate AzCIB_RS16555 hydroxymethylbilane synthase: pyruvate (3S)-3-methyl-2- glutamate gamma- arg guanylyltransferase: AzCIB_RS13710 protein D-alanyl-D-alanine- phosphatase deacylase: deacylase: AzCIB_RS22885 cob(I)yrinic acid aspartate/ tyrosine/aromatic succinyltransferase: AzCIB_RS01010 aminotransferase: Ada: ada selenide NapA FlgL an S-sulfanyl-[L- synthase/GTP glutamyl-tRNA synthase: hemC AzCIB_RS10860 oxaloacetate threonine semialdehyde cobU ligase: mpl [+ 2 isozymes] 2: mrdA endopeptidase: dacB SerB: serB AzCIB_RS16075 AzCIB_RS16075 N-acetyl-D- ala uroporphyrinogen-III [+ 2 isozymes] 3-deoxy- oxopentanoate 2 AzCIB_RS05290 4-hydroxy-3- a,c-diamide reductase: tyrosine/aromatic ammonia-lyase: aminotransferase: N -succinyl- arginase: AzCIB_RS03830 methylated-DNA-- C-methyltransferase: uroporphyrinogen-III cysteine desulfurase] 4-hydroxybenzoate cyclohydrolase II: 7,8- dehydrogenase: D-alanyl-D-alanine serine ala muramate octaprenylbenzoate adenosyltransferase: a [hydroxymethylbilane D-arabino- aminotransferase: 3-(4- AzCIB_RS13945 L-arginine rocF an L-1- adenosyl- C-methyltransferase: octaprenyltransferase: AzCIB_RS01795 dihydroneopterin AzCIB_RS03870 AzCIB_RS21805 putA [protein]-cysteine S- UDP-N-acetylmuramoyl- a tRNA Cys cobA synthase] ES intermediate heptulosonate 3-(4- AzCIB_RS13945 malate (2Z)-2-aminobut- 3-methylbutanoyl- hydroxyphenyl) (S)-1-pyrroline- acyl-carrier protein cobinamide 3-(4- a [bis(guanylyl carboxypeptidase/ a N- cys UbiD family AzCIB_RS20905 AzCIB_RS04470 3 L-ornithine phosphatidylethanolamine methyltransferase: cobA 3'-triphosphate (S)-4-amino-5- a purine L-alanyl-γ-D- ala molybdopterin) D-alanyl-D-alanine- D-tyrosine Tyr tRNA asp D-aspartate [+ 2 isozymes] GTP [corrinoid 7-phosphate hydroxyphenyl) dehydrogenase: 2-enoate CoA pyruvate 5-carboxylate phosphate hydroxyphenyl) phe D-ala acetylglucosamine- a tRNA decarboxylase: dihydroneopterin oxopentanoate hydroxymethylbilane (2S)-2- AzCIB_RS16065 glutamyl-meso-2,6- RS17445 FliD [+ 2 isozymes] cyclohydrolase pyruvate AzCIB_RS09250 (R)-lactate ribonucleoside pyruvate cofactor endopeptidase: dacB -N-acetylmuramyl- precorrin-2 an S-sulfanyl-[cysteine AzCIB_RS13310 4-hydroxy-3- adenosyltranferase]- triphosphate synthase: hemC 3-dehydroquinate acetyl-CoA formate methylbutanoyl-CoA isovaleryl-CoA ornithine- II: ribA glutamate-1- 2 5'-diphosphate diaminopimeloyl- chaperone]-S- precorrin-2 cob(II)inamide synthase: aroB dehydrogenase: N -succinyl- -oxo-acid (tetrapeptide) desulfurase]-[disordered- 4-hydroxy-3- octaprenylbenzoate 2,5-diamino-6- diphosphatase: semialdehyde a [hydroxymethylbilane a [protein]-S- D-alanine sulfanyl-L-cysteine AzCIB_RS15815 L-ornithine transaminase: a guanine in DNA UDP-N- pyrophosphoryl- form scaffold polyprenylbenzoate 4-hydroxy-3- (5-phospho-D- nudB 2,1- superpathway of thiamine diphosphate biosynthesis II synthase] ES intermediate (S)-malate citrate (Si)- methyl-L-cysteine precorrin-2 C(20)- 4 3-dehydroquinate bifunctional enoyl- acetaldehyde 2-iminobutanoate L-glutamate-5- D-ala acetylmuramoyl- undecaprenol protein] complex ribosylamino) 7,8- synthase: gltA 3-methylcrotonyl- homogentisate rocD decarboxylase: ubiD octaprenylbenzoate aminomutase: γ methyltransferase: dihydroneopterin hydroxymethylbilane fumarate hydratase: CoA hydratase/ dehydrogenase (E)-2- CoA semialdehyde L-alanyl- -D- RS23445 RS04895 5-hydroxylase: pyrimidin- [corrinoid hemL type I 3- L-glutamate-5- sirohydrochlorin cobI 2-octaprenylphenol cys synthase: hemC AzCIB_RS06610 phosphate (acetylating): methylcrotonoyl-CoA 2 glutamyl-meso-2,6- AzCIB_RS03980 4(3H)-one adenosyltranferase]- 3'-phosphate dehydroquinate citrate CO H acetyl/propionyl/ N -succinyl- trifunctional semialdehyde cob(I)inamide a holo-[hydroxymethylbilane class II fumarate acetyltransferase: AzCIB_RS07490 2 2 L-glutamate 5- diaminopimeloyl- precorrin-3A a [cysteine desulfurase]- 3,4-dihydroxy- bifunctional 5-aminolevulinate dehydratase: enoyl-CoA methylcrotonyl- transcriptional SufS family a [ThiS sulfur- synthase] Secondary Metabolite Biosynthesis hydratase: fumC bifunctional AzCIB_RS20780 acetaldehyde 4-maleyl- semialdehyde D-alanine S-sulfanyl-[disordered- 5-all-trans- diaminohydroxyphosphoribosylaminopyrimidine cob(I)yrinic acid AzCIB_RS09685 hydratase: 2-oxobutanoate CoA carboxylase regulator/proline porphobilinogen cysteine carrier protein] aconitate hydratase phosphate dehydrogenase acetoacetate RS23450 form scaffold octaprenylbenzoate deaminase/5-amino-6-(5-phosphoribosylamino) a,c-diamide AzCIB_RS03180 subunit alpha: dehydrogenase/L- 3-(all-trans D-erythro-7,8- desulfurase: fumarate 2/2-methylisocitrate acetyltransferase: pta (acetylating): γ cobalt- uracil reductase RibD: ribD adenosyltransferase: synthase: hemB 3-dehydroshikimate methylerythritol phosphate pathway I [+ 2 isozymes] AzCIB_RS15805 maleylacetoacetate glutamate gamma- (S)-1-pyrroline- a ring-opened 7- a mature peptidoglycan a DNA containing L-alanyl- -D- an N-terminal- a peptide with protein] complex -octaprenyl) dihydroneopterin sufS epoxysqualene myo-inositol dehydratase: AzCIB_RS22035 H O a [glutamine- a D-tryptophanyl- MoO - an L-asparaginyl- 5-amino-6-(5- porphobilinogen methylguanine diphosphate 2 glutamyl-meso- 2 sec sirohydrochlorin cysteine cobO chorismate (2S,3S)-3-hydroxy-2- isomerase: maiA 2 semialdehyde 5-carboxylate (meso-diaminopimelate an apurinic/ UDP-N-acetyl- Trp L-methionyl-L- Asn an N-terminal ser a tRNA dihydroneopterin shikimate biosynthesis biosynthesis fumarate reductase/ AzCIB_RS14480 methylcrotonoyl- N - hypoxanthine ATP synthetase]- [tRNA ] ATP molybdopterin [tRNA ] ATP precorrin-3B desulfurase: benzene-1,2-diol phospho-D- synthase: hemB [+ 3 isozymes] lipoate biosynthesis D-glyceraldehyde dehydrogenase: in DNA containing) apyrimidinic site diaminopimelate α-D-muramate alanyl-[protein] L-methionine biotin 3-methoxy-4- cob(I)yrinic acid aldolase: dehydrogenase: pyruvate succinate acetyl phosphate methylbutanoyl-CoA CoA carboxylase: maleylacetoacetate succinylglutamate pyrroline-5- PRPP sufS bifunctional 2- D-ribulose ribosylamino)uracil aminodeoxychorismate/ an [L-cysteine a carboxy- 3-phosphate aconitate hydratase propanoyl-CoA putA L-tyrosine cofactor hydroxy-5-all-trans a,c-diamide and incorporation I (2E,6E)-farnesyl D-glucopyranose dehydrogenase acetaldehyde AzCIB_RS15810 isomerase: maiA carboxylate RS12760 precorrin-3B C(17)- polyprenyl-6- 5-phosphate bifunctional AzCIB_RS16085 anthranilate synthase porphobilinogen desulfurase]-S- adenylated-[ThiS aroE AcnA: acnA [+ 2 isozymes] -octaprenylbenzoate adenosyltransferase: diphosphate 6-phosphate flavoprotein subunit: acetate kinase: 4-fumaryl- reductase: bifunctional DNA- endolytic endonuclease RdgB/HAM1 family UDP-N- D-tyrosyl- type I methionyl aminoacyl-tRNA type I methionyl serine- methyltransferase: an S-sulfanyl-[cysteine hydroxyphenol diaminohydroxyphosphoribosylaminopyrimidine dihydroneopterin component II: sulfanyl-L-cysteine sulfur-carrier protein] D-glyceraldehyde 1-deoxy-D- squalene 3-methylglutaconyl- glu cobalt-factor III bifunctional AzCIB_RS04470 an octanoyl-[acp] shikimate AzCIB_RS10370 AzCIB_RS11205 acetoacetate AzCIB_RS19460 formamidopyrimidine transglycosylase hypoxanthine-guanine III: nth non-canonical acetylmuramate:L- bifunctional [glutamate- tRNA(Tyr) molybdenum cofactor aminopeptidase: hydrolase: aminopeptidase: biotin--[acetyl- -tRNA cobJ desulfurase]-S- methylase/3- deaminase/5-amino-6-(5-phosphoribosylamino) aldolase: folB AzCIB_RS18710 hydroxymethylbilane 3-phosphate synthase cis-aconitate CoA 3,4-dihydroxy- xylulose-5- glycosylase/ phosphoribosyltransferase: purine NTP alanyl-gamma-D- -ammonia ligase]- guanylyltransferase: map CoA-carboxylase] sulfanyl-[disordered- demethylubiquinol 3- synthase: hemC cysteine lipoyl(octanoyl) HpnC: [+ 3 isozymes] acetate/propionate 2-methylacetoacetyl-CoA MltG: mltG bifunctional DNA- deacylase: map AzCIB_RS02955 ligase: uracil reductase RibD: ribD adenosylcobinamide 6-(hydroxymethyl) [+ 2 isozymes] 1-deoxy-D- shikimate kinase: phosphate Ins(3)P glu AzCIB_RS03715 pyrophosphatase: mobA ligase: precorrin-4 2-butanone- 5-amino-6-(5- desulfurase: transferase bifunctional family kinase: propanoyl pro DNA-(apurinic [+ 5 isozymes] formamidopyrimidine glutamyl- meso- adenylyl-L-tyrosine AzCIB_RS14590 type I methionyl aminoacyl-tRNA type I methionyl serS form scaffold O-methyltransferase 2-methoxy- -7,8-dihydropterin gly synthase: hpnC ethanol RS01160 4-phosphate 4-amino-4- preuroporphyrinogen xylulose-5- LipB: lipB AzCIB_RS20810 succinate aconitate hydratase phosphate or apyrimidinic hypoxanthine-guanine rdgB diaminopimelate phosphorylase/ aminopeptidase: hydrolase: aminopeptidase: AzCIB_RS02840 precorrin-4 C(11)- protein] complex UbiG: ubiG 6-(all-trans- phospho-D- bifunctional sufS a [lipoyl-carrier protein] AzCIB_RS16550 AzCIB_RS20785 acetyl-CoA C- glycosylase/ aminoacyl-tRNA synthase/GTP 2-amino-4-hydroxy-6- deoxychorismate phosphate presqualene inositol 2/2-methylisocitrate site) lyase: mutM phosphoribosyltransferase: inorganic ligase: mpl [glutamate-- adenylyl ribitylamino)uracil 6 shikimate 3- acetate kinase: fumarate a mature peptidoglycan a mature peptidoglycan DNA-(apurinic deacylase: map AzCIB_RS22885 map cobalt-precorrin-3 methyltransferase: 2-methoxy- octaprenyl)phenol adenosylcobinamide hydroxymethyldihydropteridine uroporphyrinogen- [+ 2 isozymes] synthase: N -octanoyl-L-lysine diphosphate monophosphatase: acetate acyltransferase: HMG-CoA L-phenylalanine molybdenum an L-seryl- cyclohydrolase II: dehydratase: γ AzCIB_RS21465 diphosphatase: ammonia-ligase] biotinyl-5'- 6-(all-trans- 2-octaprenyl-6- kinase/ phosphate AzCIB_RS11205 with (L-alanyl- -D- strand (non- or apyrimidinic AzCIB_RS16075 sec cobM AzCIB_RS01795 diphosphokinase: folK III synthase: AzCIB_RS16550 lipoyl 1-deoxy-D-xylulose synthase AzCIB_RS13735 AzCIB_RS14480 AzCIB_RS12425 degradation II (anaerobic) AzCIB_RS15365 adenylyltransferase: cofactor [tRNA ] octaprenyl)phenol methoxyphenyl a thiocarboxylated- hydroxymethylglutaryl- a [DNA]- 2,6-diamino-4- glutamyl-meso-2,6- reducing terminus) site) lyase: mutM UDP-N-acetyl- adenylate a [cysteine adenosylcobinamide- (7,8-dihydropterin- AzCIB_RS03935 synthase: lipA bifunctional 3- 5-phosphate HpnD: hpnD inositol acetyl-CoA C- acetate/ a 5'-phospho- glnE an N-terminal L- RS01200 precorrin-5 1-deoxy-L- AIR [ThiS sulfur- 1-deoxy-D-xylulose presqualene CoA lyase: L-valine degradation L-histidine degradation I nucleotide- hydroxy-5-(N-methyl) 4-oxo-2-pentenal α Asn 2-octaprenyl-6- hydroxylase: phosphate 6-yl)methyl 2-iminoacetate [+ 2 isozymes] phosphoshikimate 1- aconitate hydratase propionate [DNA] diaminopimeloyl-D- -D-muramoyl- met alanyl-[protein] asn tRNA met a peptide desulfurase]-(S- glycero-tetrulose 4-aminobenzoate carrier protein] 5-phosphate 1-deoxy-D-xylulose- monophosphatase: ATP NADPH repair (prokaryotes) acyltransferase: III (oxidative phe methoxyphenyl AzCIB_RS03980 ARP guanylyltransferase: uroporphyrinogen-III a [lipoyl-carrier diphosphate AcnA: acnA AzCIB_RS02130 3'-phosphate formamidopyrimidine alanine) tetrapeptide L-alanyl-γ-D- a tRNA Trp sulfanyl) -[disordered- diphosphate carboxyvinyltransferase/ AzCIB_RS20990 family kinase: IMP a 3'-terminal a 5'-phospho- + D-tryptophan 2 2-methoxy-6-all 4-phosphate phosphomethylpyrimidine 5-phosphate AzCIB_RS04250 biosynthesis Stickland reaction) aspartate/ H cobalt-precorrin-4 hydroxylase: protein]-N 6 -[(R)- phosphate glutamyl-meso-2,6- a [glutamine form scaffold cobU cytidylate kinase: reductoisomerase: presqualene D-threo-isocitrate AzCIB_RS20785 acetoacetate his unsaturated sugar [DNA] AzCIB_RS03980 trans-octaprenyl- uroporphyrinogen synthase ThiC: thiC thiazole synthase: NADPH tyrosine/aromatic diaminopimelate synthetase]-O protein] complex dihydropteroate dihydrolipoyl]-L-lysine AzCIB_RS18075 diphosphate myo-inositol val 2-methoxy-6-all 1,4-benzoquinol 6,7-dimethyl-8- adenosyl-cobinamide decarboxylase: AzCIB_RS19255 AzCIB_RS10955 aminotransferase: histidine 4 -(5'-adenylyl) RS00175 synthase: folP 5-enolpyruvoyl- synthase NADP-dependent acetyl-CoA propanoyl-CoA propanoate precorrin-6A ribityllumazine phosphate AzCIB_RS23425 HMP-P ADP branched-chain AzCIB_RS03830 ammonia- trans-octaprenyl- bifunctional thiazole synthase: shikimate 3- -L-tyrosine synthase: MEP HpnD: hpnD F0F1 ATP isocitrate amino acid lyase: hutH 1,4-benzoquinol demethylmenaquinone bifunctional 7,8- phosphomethylpyrimidine AzCIB_RS21960 phosphate aspartate/ cobalt- AzCIB_RS01790 coproporphyrinogen III squalene synthase: dehydrogenase: transaminase: urocanate a [cysteine desulfurase]- bifunctional methyltransferase/2- tyrosine/aromatic precorrin-5A adenosylcobinamide dihydropteroate kinase: AzCIB_RS19390 2-[(2R,5Z)-2-carboxy- chorismate 2-C-methyl-D- synthase AzCIB_RS00395 AzCIB_RS16340 glycine cleavage a 7,8-dihydro- a peptidoglycan dimer (meso Nα,Nε-diacetyl-lysyl- a [glutamine a [protein]- an N-terminal- an N-terminal- demethylmenaquinone methoxy-6-polyprenyl- oxygen-dependent 3-methyl-2-AzCIB_RS04495 menadione NADH H + a protein with serotonin (2E,6E)-farnesyl [scaffold protein- kinase/ bifunctional bifunctional synthase: erythritol 4-phosphate (R)-NADPHX aminotransferase: urocanate 8-oxoguanine -diaminopimelate containing) acyl-carrier protein a medium glutathione synthetase]-O L-glutamine L-methionyl-L- L-methionyl-L- glu ala 3-sulfino-L-alanine TolB methyltransferase/2- 1,4-benzoquinol 6,7-dimethyl-8-(1- 5,6-dimethylbenzimidazole 4-methylthiazol-5(2H)- HpnC: atpB atpE NADP-dependent bifunctional a [glycine-cleavage D-alanyl-D-alanine a disulfide bond GTP 2-phospho- diphosphate precorrin-6B (2Fe-2S)] complex adenosylcobinamide- tetrahydrofolate coproporphyrinogen hydroxymethylpyrimidine aroC cytidylyltransferase: L-citrulline degradation oxobutanoate 3-phenyl-2-AzCIB_RS13945 hydratase: in DNA chain fatty acid 4 -(5'-adenylyl) seryl-[protein] valyl-[protein] methoxy-6-polyprenyl- methylase UbiE: ubiE D-ribityl)lumazine ylidene]ethyl phosphate hpnC AzCIB_RS00410 isocitrate ADP-dependent 6 presqualene phosphate oxidase: hemF complex H protein] N ketoisovalerate hutU -L-tyrosine L-lactate 6-methoxy-3- synthase/ adenosylcobalamin kinase/ AzCIB_RS10180 AzCIB_RS00415 dehydrogenase: NAD(P)H-hydrate glycine oxopropanoate penicillin-binding diphosphate cobalt- 1,4-benzoquinol riboflavin chorismate -[(R)-lipoyl]-L-lysine NADH-quinone penicillin- transglutaminase: guanylyltransferase: dihydrofolate salvage from cobalamin phosphomethylpyrimidine 4-(cytidine 5'- squalene AzCIB_RS00420 AzCIB_RS16335 cleavage oxidoreductase: 4-imidazolone- glutaredoxin glutamate-- SufS family methylase UbiE: ubiE methyl-2-all- synthase: protoporphyrinogen IX dehydratase/ L-citrulline indolepyruvate/ bifunctional DNA- protein 2: mrdA bifunctional AzCIB_RS19525 type I methionyl type I methionyl synthase precorrin-5B cobU synthase: folC kinase: thiD diphospho)-2-C- glycine system AzCIB_RS08920 5-propanoate oxidoreductase: nuoN binding 2-phospho-L-lactate a [co-chaperone]- 6-methoxy-3- trans-octaprenyl- AzCIB_RS01800 2-(2-carboxy-4- atpG atpD NAD(P)H-hydrate ornithine phenylpyruvate formamidopyrimidine D-alanyl-D-alanine acyl-ACP-- 3: grxC bifunctional [glutamate- aminopeptidase: aminopeptidase: cysteine ligase: cysteine HpnD: hpnD YbgF cobalt-precorrin- cob(I)alamin methyl-D-erythritol 2-oxoglutarate cleavage protein ketoisovalerate AzCIB_RS14810 nuoK protein transglutaminase guanylyltransferase: [scaffold protein- methyl-2-all- 1,4-benzoquinol adenosylcobinamide- α-ribazole 5'-phosphate 7,8-dihydrofolate methylthiazol-5- AzCIB_RS00435 epimerase: carbamoyltransferase: decarboxylase: imidazolonepropionase: glycosylase/ carboxypeptidase/ phospholipid O- glutathione- -ammonia ligase]- map map AzCIB_RS17235 desulfurase: squalene 5B (C(1))- precorrin-7 riboflavin HMP-PP 4-(cytidine 5'- system GcvH: gcvH oxidoreductase: AzCIB_RS14825 nuoI 2: mrdA domain-containing cofC (2Fe-2S)] complex trans-octaprenyl- GDP monoglutamate yl)ethyl phosphate ATP AzCIB_RS14365 argF ipdC AzCIB_RS15850 DNA-(apurinic D-alanyl-D-alanine- acyltransferase/ dependent adenylyl-L-tyrosine type I methionyl type I methionyl glutamate- sufS synthase methyltransferase: diphospho) (3S)-2,3- carbamoyl protein nuoH AzCIB_RS14840 D-alanyl-D-alanine protein: 1,4-benzoquinol (S)-NADPHX [+ 4 isozymes] AzCIB_RS14095 or apyrimidinic long-chain-fatty- disulfide-bond phosphorylase/ -cysteine bifunctional -2-C-methyl- epoxy-2,3- GcvH: gcvH endopeptidase: dacB nuoF nuoE AzCIB_RS01025 aminopeptidase: aminopeptidase: HpnC: hpnC AzCIB_RS20665 adenosylcobinamide- cob(II)alamin protoporphyrin IX phosphate phenylacetaldehyde N-formimino- site) lyase: mutM acid--ACP ligase: carboxypeptidase/ L-lactyl-2- riboflavin kinase/ thiamine D-erythritol a [glycine-cleavage isobutanoyl-CoA AzCIB_RS14855 oxidoreductase: [glutamate-- map map ligase: gshA squalene RS04005 cobalt- dihydrosqualene bifunctional [+ 7 isozymes]a [glycine-cleavage L-glutamate D-alanyl-D-alanine- diphospho- sulfite a [chaperone-ATP]- 3-demethylubiquinol-8 GDP phosphate glutamine- complex H protein] N 6 - AzCIB_RS01010 yghU ammonia-ligase] ala FAD synthetase: cob(I)yrinic acid ferrochelatase: kinase: ispE tRNA-uridine 2-thiolation Macromolecule Modification complex H protein] N 6 a peptidoglycan with AzCIB_RS14860 endopeptidase: dacB a [protein] N 6 - precorrin-6A [co-chaperone]- ribazoletransferase: synthase: ADP-dependent hydrolyzing aminomethyldihydrolipoyl- a [DNA]- adenylyltransferase: 5'-guanosine precorrin-8x AzCIB_RS16500 pyridoxal 5'-phosphate biosynthesis I a 7,8-dihydrofolate a,c-diamide AzCIB_RS14980 superpathway of thiamine diphosphate biosynthesis I 2-phospho-4-(cytidine and selenation (bacteria) -dihydrolipoyl-L-lysine formimidoylglutamase: a 5'-phospho- 7,8-dihydro- D,D cross-links (meso- D-ala an N-terminal an N-terminal γ-L-glutamyl- bifunctional 2- AzCIB_RS02530 AzCIB_RS19385 NAD(P)H-hydrate carbamoyl- 4-oxo-2-pentenal glnE [(5-hydroxy-1H- [scaffold protein- 3-demethylubiquinol-8 5'-diphospho)-2-C- L-lysine AzCIB_RS15855 nucleotide- [DNA] 8-oxoguanine diaminopimelate containing) a protein with met met precorrin-8X polyprenyl-6- dihydrofolate adenosyltransferase: dehydratase/ a medium-chain α ε indol-3-yl)ethyl]- L-seryl-[protein] L-valyl-[protein] D-alanine (2Fe-2S)] complex FMN D-erythrose phosphate phenylacetate 3'-phosphate + N ,N -diacetyl- GSSG cobO protoheme methyl-D-erythritol NAD menadiol reduced L- L-glutamine RS18765 methylmutase: bifunctional 2- hydroxyphenol 4-phosphate adenosylcobalamin reductase: cys preQ biosynthesis cys NAD(P)H-hydrate synthase: isobutanoate fatty acyl-[acp] lysyl-D-alanine D-ala 2-C-methyl-D- 0 glu cysteine residues a [glutamine- cobalt- AzCIB_RS20660 polyprenyl-6- methylase/3- bifunctional AzCIB_RS15940 cob(I)yrinic acid thiamine phosphate epimerase: D-erythrose- 5'-phosphate erythritol 2,4- carB carA synthetase]- precorrin-6B hydroxyphenol demethylubiquinol 3- riboflavin kinase/ pyrroloquinoline a,c-diamide SufS family SufS family AzCIB_RS14365 L-serine degradation glycine ADP hydrogenobyrinate 4-phosphate a tetrahydrofolate thiamine- cyclodiphosphate L-methionine degradation L-tyrosine a [chaperone- methylase/3- O-methyltransferase FAD synthetase: quinone biosynthesis adenosyltransferase: cysteine cysteine carbamate cleavage an [2Fe-2S] dehydrogenase: phosphate synthase: GTP NADPH system I (to L-homocysteine) ADP]-[disordered- demethylubiquinol 3- UbiG: ubiG AzCIB_RS16500 AzCIB_RS04470 desulfurase: desulfurase: glycine degradation RS21515 cluster protein AzCIB_RS03080 coenzyme A biosynthesis kinase: thiL AzCIB_RS10175 GTP ser form scaffold O-methyltransferase a PqqA peptide SAM cob(II)alamin- sufS sufS protein L-arginine degradation (reductive FAD 4-phospho- adenosylcobalamin I (prokaryotic) cyclohydrolase L-serine met N-acetyl-muramoyl-(L- a carboxy- a peptidoglycan an N-terminal- 2,6-dioxo-6- an N-terminal- cobalt-precorrin-7 protein] complex UbiG: ubiG ubiquinol-8 [corrinoid [+ 3 isozymes] 2-C-methyl-D-erythritol- [+ 3 isozymes] GcvH: gcvH VII (arginase 3 pathway) L-aspartate thiamine diphosphate Stickland reaction) 34 a peptidoglycan a D-aminoacyl- a RNA-DNA hybrid a cytidine 34 L-canavanine hydrogenobyrinate D-erythronate an [L-cysteine 2,4-cyclodiphosphate I FolE2: an [L-cysteine ammonia-lyase: methionine degradation I a 5,10-gly a uridine alanyl-γ-D-glutamyl-L- adenylated- cys dimer (S. aureus) an HmqF protein L-methionyl-L- phenylhexa- L-methionyl- met lys adenosyltranferase] (R)-4'- [+ 4 isozymes] [tRNA] decanoate Ile2 bifunctional cobalt- AzCIB_RS16555 desulfurase]-S- CO AzCIB_RS05835 adenosyltransferase: methylenetetrahydrofolate in tRNA lysyl-D-alanyl-D-alanine) [ThiS sulfur- threonyl-[protein] 3-enoate glycyl-[protein] in tRNA a,c-diamide ubiquinol-8 phosphopantothenate desulfurase]-S- 2 gly amino-acid N- bifunctional flavodoxin- 7,8- NADH repair (prokaryotes) arg precorrin-7 (C(5))- sulfanyl-L-cysteine a [ThiS sulfur- [+ 2 isozymes] sulfanyl-L-cysteine L-serine AzCIB_RS02300 1,6-anhydro-N- carrier protein] acetyltransferase: RS04295 cobalt chelatase: dependent dihydroneopterin glycine reductase: asp penicillin- ribonuclease methyltransferase/ an [Fe-S cluster phosphopantothenoylcysteine cysteine ammonia-lyase: SAM AzCIB_RS04265 tRNA arginase: (3R)-3-hydroxy-2-oxo- cob(I)alamin- carrier protein] (E)-4-hydroxy- AzCIB_RS10470 tRNA uridine-5- acetylmuramyl- penicillin-binding binding aminoacyl-tRNA bifunctional type I methionyl 2-hydroxy- type I methionyl cobalt-precorrin- AzCIB_RS17355 biosynthesis thiamine diphosphate salvage II a PqqA peptide with decarboxylase/ 3'-triphosphate NADH aspartate/ HI: rnhA rocF FeMo cofactor biosynthesis desulfurase: 3-methylbut- 2-aminoprop-AzCIB_RS10530 arginase: rocF carboxymethylaminomethyl(34) L-alanine protein 2: mrdA IscS subfamily protein deacylase: acyl-ACP-- aminopeptidase: 6-oxo-6- aminopeptidase: bifunctional lysidine(34) 6B (C(15))- cob(II)yrinate chaperone]-ATP 4 phosphooxybutanoate linked Glu-Tyr residues [corrinoid phosphopantothenate-- acetyl phosphate tyrosine/aromatic ribonuclease sufS 6-carboxytetrahydropterin synthesis enzyme MnmG: mnmG amidase 2: mrdA AzCIB_RS16075 phospholipid O- map phenylhexa- map synthetase 3-phosphoserine/ adenosyltranferase] cysteine ligase CoaBC: coaBC 2-enyl- a [TusA sulfur- 2-enoate aminotransferase: D-alanyl-D-alanine cysteine HII: rnhB glutamate N- methyltransferase: a,c-diamide a [4Fe-4S] iron- 4-amino-2-methyl-5- D-glyceraldehyde (R)-4'- [+ 2 isozymes] synthase QueD: queD AmpD: ampD 2,4-dienoate TilS: tilS phosphohydroxythreonine pyruvate cob(I)yrinic acid D-glyceraldehyde diphosphate carrier protein]-S- acetate kinase: AzCIB_RS13945 tRNA uridine-5- carboxypeptidase/ desulfurase: D-alanyl-D-alanine D-tyrosyl- acyltransferase/ type I methionyl type I methionyl acetyltransferase/ RS04425 AzCIB_RS20670 sulfur cluster pyrimidinemethanol 3-phosphate phosphopantothenoyl- a [ThiI sulfur- a carboxy- urea hydrolase: urea transaminase: serC a,c-diamide 3-phosphate synthase: ispG 6-carboxy-5,6,7,8- sulfanyl-L-cysteine L-ornithine AzCIB_RS11205 carboxymethylaminomethyl(34) D-alanyl-D-alanine- AzCIB_RS13710 carboxypeptidase/ tRNA(Tyr) long-chain-fatty- aminopeptidase: aminopeptidase: amino-acid L-canaline bifunctional L-cysteine carrier protein]-S- adenylated-[ThiS tetrahydropterin L-glutamine SAH aspartate/ bphD cobalt-precorrin-8 4-phosphooxy- 2-amino-4-[5-(2-amino- adenosyltransferase: AIR 1-deoxy-D- (E)-4-hydroxy-3- acetate/propionate synthesis GTPase MnmE: mnmE ditrans,octacis- a peptidoglycan endopeptidase: dacB [+ 2 isozymes] D-alanyl-D-alanine- deacylase: acid--ACP ligase: map DNA a nucleoside 5'- map acetyltransferase a lysidine 34 hydroxymethylpyrimidine 1-deoxy-D- bifunctional tyr sulfanyl-L-cysteine sulfur-carrier protein] (R)-NADHX degradation I ornithine tyrosine/aromatic thioredoxin L-threonine 2-carboxylatoethyl)-2- cobO xylulose-5- methylbut-2-en- 7-carboxy-7- 2-iminopropanoate family kinase: undecaprenyldiphospho- pentapeptide endopeptidase: dacB AzCIB_RS14590 AzCIB_RS01010 monophosphate ArgJ: argJ in tRNA Ile2 molybdopterin biosynthesis xylulose-5- phosphopantothenoylcysteine bifunctional aminotransferase: pathway kinase/ phosphomethylpyrimidine phosphate 1-yl diphosphate deazaguanine adenosylhomocysteinase: cyclodeaminase: N-acetyl-(N- (2Z)-2- N-acetyl-L- 4-hydroxythreonine- hydroxyphenyl]pentanedioate cob(I)yrinic acid decarboxylase/ a [TusD sulfur- AzCIB_RS20785 AzCIB_RS03830 a 5-carboxymethylaminomethyluridine 34 N-acetyl-muramoyl-(L- a thiocarboxylated- an N-terminal L- an N-terminal RS04420 a NifB protein phosphomethylpyrimidine phosphate synthase ThiC: thiC synthase ADP-dependent gln AzCIB_RS02275 AzCIB_RS15840 a 7,8-dihydrofolate γ benzoate hydroxypenta- methionine 4-phosphate a,c-diamide phosphopantothenate-- synthase: carrier protein]-S- oxaloacetate in tRNA acetylglucosaminyl)muramate alanyl- -D-glutamyl- D-ala ala [ThiS sulfur- a peptidoglycan met threonyl-[protein] met glycyl-[protein] an oxidized with a K-cluster kinase: thiD synthase: QueE: queE NAD(P)H-hydrate Asp-tRNA(Asn) acetate AMP an uncharged a decanoyl- 2,4-dienoate dehydrogenase adenosyltransferase: cysteine ligase CoaBC: coaBC AzCIB_RS16550 a thiocarboxylated- 4-hydroxy- sulfanyl-L-cysteine L-lysyl-D-alanine) carrier protein] with D,D cross- D-ala a D-amino acid cobyrinate ATP thioredoxin AzCIB_RS16550 HMP-P dehydratase/ /Glu-tRNA(Gln) pro tRNA HmqF protein HMP-P AzCIB_RS04470 1-deoxy-D-xylulose 3-methylbut- 7-carboxy-7- L-homocysteine link (S. aureus) cys PdxA: pdxA 2-amino-4-[3-(2-amino-2- 2-iminoacetate [ThiS sulfur- NAD(P)H-hydrate pyruvate amidotransferase: adenosylcob(III) 4'-phosphopantetheine 5-phosphate 2-enyl deazaguanine L-glutamine L-asparagine molybdopterin- GTP 3-amino-1- 1-deoxy-D- carboxylatoethyl)-6-oxocyclohexa- phosphomethylpyrimidine carrier protein] epimerase: gatB gatA gatC L-glutamate RS02050 phosphomethylpyrimidine alamin-[corrinoid 4-hydroxy- diphosphate 7-cyano-7- degradation II degradation I synthase SufS family thioredoxin- hydroxyacetone xylulose 5- 1,4-dien-1-yl]pentanedioate kinase: AzCIB_RS19390 a [TusE sulfur AzCIB_RS14365 a reduced a [ThiI sulfur- a [dinitrogen a NifB protein kinase: AzCIB_RS19390 adenosyltranferase] pantetheine- 3-methylbut- reductase: (S)-NADHX [+ 6 isozymes] degradation I a heme(III)-bound an N-formyl-L- an N-modified a [protein]-L- phosphoenol cysteine 1-phosphate phosphate thiazole synthase: deazaguanine 34 carrier protein]-S methanethiol O-acetyl-L- ubiquinone-6 isobutanal ω α NADH acetylene adenylyltransferase GTP 3',8- disulfide phosphate bifunctional a uridine in tRNA glu L-alanine a CcmAB complex electron-transfer methionylaminoacyl- carrier protein]- cys reductase]-N - - β-isoaspartate pyruvate cob(II)yrinate with an L-cluster bifunctional 5-(2-hydroxyethyl) cob(I)yrinic acid AzCIB_RS19255 2-enyl ispH synthase -sulfanylcysteine gln homoserine CcmCDE complex aminoacyl-[tRNA] dITP dGDP ATP roseoflavin MoeB: moeB desulfurase: cyclase reductase: adenylyltransferase: hydroxymethylpyrimidine degradation IV asn flavoprotein tRNA L-cysteine ( ADP-D-ribosyl) protein-L- nitrogenase a,c-diamide a carboxy- hydroxymethylpyrimidine -4-methylthiazole pyridoxine 5'- a,c-diamide thiazole synthase: diphosphate QueC: queC bifunctional glutamate glu RdgB/HAM1 family non- 5'-phosphate sufS trxB nitrogenase 6-(2-amino-2-carboxylatoethyl) kinase/ NAD de novo biosynthesis asparaginase: -L-arginine isoaspartate O- molybdenum- MoaA: kinase/ adenosyltransferase: coaD reductase: ADP-dependent NAD-glutamate NAD(+) FlgA adenylated [+ 3 isozymes] iron- phosphate phosphomethylpyrimidine AzCIB_RS21960 I (from aspartate) tRNA 2- synthase AzCIB_RS21080 bifunctional O-acetylhomoserine acetaldehyde canonical purine NTP methyltransferase: iron protein moaA -1,2,3,4-tetrahydroquinoline- 3'-dephospho- ispH preQ NAD(P)H-hydrate dehydrogenase: ala cytochrome c electron transfer peptide IscS subfamily aminoacyl-tRNA [small subunit of phosphomethylpyrimidine synthase: cobO 0 thiouridine(34) subunit dehydrogenase pyrophosphatase: rdgB diphosphatase: an [L-cysteine (8S)-3',8-cyclo-7,8- molybdenum 2,4-dicarboxylate kinase: thiD IPP type II aminocarboxypropyltransferase/ flavoprotein- AzCIB_RS19225 pyruvate bifunctional subunit molybdopterin kinase: thiD AzCIB_RS13795 CoA 2-[(2R,5Z)-2-carboxy- synthase dehydratase/ beta: gltD AzCIB_RS02060 alanine biogenesis heme- deformylase: cysteine hydrolase: ADP-ribosyl- nudC desulfurase]-S- dihydroguanosine a reduced cofactor 4-methyl-5-(2- cob(I)yrinic acid asp asparaginase: cysteine synthase: AzCIB_RS10725 ubiquinone (acetylating): nucleotide kinase: pyk riboflavin kinase/ beta: nifK 2-oxoglutarate 4-methylthiazol-5(2H)- NAD(P)H-hydrate glu 2-oxoglutarate dehydrogenase: ald transporting def desulfurase: AzCIB_RS02955 [dinitrogen protein-L- synthase] sulfanyl-L-cysteine 5'-triphosphate thioredoxin biosynthesis phosphooxyethyl) a,c-diamide dephospho- HMP-PP MnmA: mnmA protein S-nitrosylation AzCIB_RS16975 AzCIB_RS07490 pyrophosphohydrolase: HMP-PP ylidene]ethyl phosphate L-aspartate epimerase: O-acetylhomoserine ATPase oxidoreductase: AzCIB_RS13710 aminoacyl-tRNA reductase] isoaspartate(D- pyruvate FAD synthetase: [+ 2 isozymes] cyclic pyranopterin protein pyridoxine adenosyltransferase: CoA kinase: and denitrosylation pyruvate peptide AzCIB_RS07710 reduced β- FlgJ homocitrate thiazole oxidase: nadB Metabolic Regulator AzCIB_RS14365 asp aminocarboxypropyltransferase: CcmA: ccmA AzCIB_RS07280 acetaldehyde hydrolase: aspartate) O- kinase: pyk AzCIB_RS16500 ethene monophosphate NifN: nifN 5'-phosphate 6-(2-amino-2-carboxylatoethyl) AzCIB_RS04470 AzCIB_RS02820 a 2-thiouridine 34 deformylase: [+ 2 isozymes] hydrolase: nicotinamide D- synthase: nifV thiamine 2-iminosuccinate Biosynthesis a [protein]- AzCIB_RS14750 [+ 2 isozymes] dehydrogenase draG dIMP methyltransferase: AMP synthase a NifEN protein -7-hydroxy-8-oxo-1,2,3,4,7,8- in tRNA AzCIB_RS14305 AzCIB_RS22885 ribonucleotide thiamine pyridoxamine coenzyme A phosphate DMAPP L-cysteine NADH (acetylating): AzCIB_RS17910 roseoflavin a thiocarboxylated MoaC: moaC complex containing hexahydroquinoline- adenosylcobalamin a [ThiI sulfur- a protein L-β- (2R)-homocitrate phosphate 5'-phosphate synthase: quinolinate ppGpp metabolism tRNA uridine-5- a heme(III)-bound an oxidized AzCIB_RS22035 pyruvate adenine [small subunit of cyclic 2,4-dicarboxylate bis(guanylyl molybdopterin) Fatty Acid and Lipid Degradation a CcmABCD complex + a [dinitrogen an L-cluster synthase: synthase carboxymethylaminomethyl(34) acetate CcmE protein electron-transfer H ubiquinol-6 ala carrier protein]- ADP-D-ribose isoaspartate dGTP RS10455 oxidase: cofactor sulfurylation AzCIB_RS19385 met formate a L-methionylaminoacyl- an N-modified an uncharged reductase]- dinucleotide molybdopterin pyranopterin AzCIB_RS19385 NadA: nadA synthesis enzyme MnmG: mnmG S-sulfanyl- α-methyl ester AzCIB_RS13265 pppGpp flavoprotein tRNA amino acid tRNA L-arginine synthase] phosphate a [protein] 3- oleate β-oxidation isobutanoyl-CoA NADH H + L-cysteine pyridoxamine tRNA uridine-5- β 6-(2-amino-2-carboxyethyl) cys quinolinate Polyprenyl Biosynthesis nitrosothio- fatty acid -oxidation I (generic) thiamine 5'-phosphate benzimidazolyl thiamine phosphate carboxymethylaminomethyl(34) molybdopterin a NifEN protein -7,8-dioxo-1,2,3,4,7,8- 2-methyladeninyl L-alanine phosphate oxidase: adenosylcobamide biosynthesis bifunctional (p)ppGpp synthesis GTPase MnmE: mnmE oleate a (3Z)-alk-3- RS10460 synthase sulfur complex containing acyl carrier hexahydroquinoline adenosylcobamide biosynthesis SufS family thiamine- polyisoprenoid biosynthesis (E. coli) GlcNAc-1,6- an N-terminal- thiamine- from adenosylcobinamide-GDP synthetase/guanosine- a 5-carboxymethylaminomethyl- enoyl-CoA a purine base quinoxaline-2- 3-aci- a mature (4R)-4-hydroxy- (S)-1-pyrroline- phosphoenol pyridoxamine carrier subunit: an M-cluster AzCIB_RS20745 from adenosylcobinamide-GDP cysteine phosphate long-chain-fatty- adeninyl adenosylcobamide biotin biosynthesis from protein activation 2,4-dicarboxylate 3',5'-bis(diphosphate) 3'- 34 lesion in DNA aryl-carrier protein anhMurNAc-L-Ala- acyl-carrier protein peptidoglycan L-methionyl-L- 2-oxoglutarate 5-carboxylate a protein AzCIB_RS01860 phosphate 2-thiouridine in tRNA Amine and Polyamine Degradation carboxyl adenylate nitropropanoate octanoate (n) XTP dADP pyruvate 5'-phosphate dADP biosynthesis from pyrroloquinoline- benzimidazole desulfurase: kinase: thiL acid--CoA ligase: γ-D-Glu-DAP-D-Ala (meso-DAP cysteinyl-[protein] trifunctional 8-amino-7-oxononanoate I kinase: thiL PLP 2-methyladenine NaMN pyrophosphohydrolase: IPP pyridoxamine ATP- molybdopterin an apo acyl- sufS a [protein]- AzCIB_RS15145 RdgB/HAM1 family non- transcriptional adenosylcobalamin- adenosylcobinamide-GDP quinone synthase AzCIB_RS10140 S-nitrosoglutathione containing) 5'-phosphate dependent (8S)-8-amino-7- thiamine carrier protein thiamine diphosphate ethanolamine utilization bifunctional DNA- nitronate bifunctional canonical purine NTP dependent synthase holo-ACP PqqC: pqqC [+ 3 isozymes] nicotinate-nucleotide L-cysteine [+ 7 isozymes] 4-aminobutanoate acyl carrier 1,6-anhydro-N- regulator/proline oxidase: RS10500 oxononanoate an [L-cysteine bifunctional (p)ppGpp a (2E)-2- 4-aminobutanoate formamidopyrimidine monooxygenase: bifunctional acyl- type I methionyl 4-hydroxy-2- pyrophosphatase: rdgB ribonucleoside- protease adenine catalytic subunit adenosylmethionine- a NifDK protein diphosphate synthase: folate transformations III (E. coli) adenylyltransferase: a 5-aminomethyl-2- S-(hydroxymethyl) dehydrogenase/L- pyruvate AzCIB_RS13265 pyrroloquinoline quinone synthetase/guanosine- degradation I degradation III protein: acetylmuramyl- ACP--phospholipid endolytic aminopeptidase: subunit MoaE: moaE containing an M-cluster benzimidazole desulfurase]-S- 34 oleoyl-CoA enoyl-CoA glycosylase/ AzCIB_RS07410 oxoglutarate nucleotide glutamate gamma- diphosphate RseP -8-amino-7- AzCIB_RS13790 nadD thiouridine in tRNA glutathione enoyl-CoA ethanolamine AzCIB_RS08705 L-alanine O-acyltransferase/ transglycosylase map kinase: pyk pyridoxamine HslV: hslV a holo acyl- adenosylcobinamide- ribotide sulfanyl-L-cysteine 3',5'-bis(diphosphate) 3'- DNA-(apurinic nitronate aldolase/2- pyrophosphohydrolase: semialdehyde reductase: oxononanoate a tetrahydrofolate 2-methyladenine nicotinate adenine dehydrogenase/ acyl-CoA hydratase: 4-aminobutanoate 4-aminobutanoate [+ 4 isozymes] amidase long-chain-fatty- MltG: mltG pyruvate 5'-phosphate carrier protein GDP phosphate cysteine pyrophosphohydrolase: DMAPP a 2,3,4-saturated long-chain fatty ethanolamine or apyrimidinic monooxygenase: type I methionyl dehydro-3-deoxy- AzCIB_RS07710 dehydrogenase: AzCIB_RS14795 a peptide molybdopterin transaminase: adenosylcobinamide- ribotide phosphate bis(guanylyl dinucleotide class III alcohol dehydrogenase: acyl-CoA AzCIB_RS03180 a 2,3,4- 4-aminobutyrate- 4-aminobutyrate- AmpD: ampD acid--ACP ligase: kinase: pyk oxidase: RS10590 desulfurase: 5-methylbenzimidazolyl AzCIB_RS01090 fatty acid acid--CoA ligase: ammonia- site) lyase: mutM AzCIB_RS21120 [+ 5 isozymes] aminopeptidase: phosphogluconate putA ADP AzCIB_RS10880 phosphopantothenate biosynthesis I molybdopterin) dehydrogenase: AzCIB_RS22980 dehydrogenase:[+ 2 isozymes] saturated (3R)-3- -2-oxoglutarate -2-oxoglutarate AzCIB_RS01010 XMP AzCIB_RS20745 (7R,8S)- GDP adenosylcobinamide- sufS adenosylcobamide biosynthesis NAD+ synthase: NAD+ synthase: a 5-methylaminomethyl- AzCIB_RS08795 lyase: eutC eutB a quinoxaline-2- map aldolase: eda methionine cofactor AzCIB_RS05045 AzCIB_RS07365 a 2,3,4- transaminase: transaminase: LptF diaminononanoate GDP from adenosylcobinamide-GDP AzCIB_RS15355 AzCIB_RS15355 34 [+ 24 isozymes] [+ 7 isozymes] hydroxyacyl-CoA carboxyl-[aryl- N-acetyl-β-D- L-alanyl-γ-D- a mature GlcNAc-1,6- glu PLP adenine ribotide synthase: metH [+ 2 isozymes] 2-thiouridine in tRNA a 2,3,4-saturated gabT a [DNA]- a 5'-phospho- a modified AMP [unspecified pyruvate CysA 3-methyl-2-oxobutanoate adenosylcobinamide- ribazoletransferase: a [bis(guanylyl S-(hydroxysulfenamide) (2E,9Z)- [+ 24 isozymes] saturated (3S)-3- acetaldehyde succinate gabT 4-oxo-2-pentenal carrier protein] glucosamine-1,6- glutamyl-meso-2,6- peptidoglycan anhMurNAc- GTP ppGpp fatty acyl CoA succinate nucleotide- 3-oxopropanoate nitrite (n) dATP adenosylcobinamide- phosphate dethiobiotin 5-methylbenzimidazole + tRNA 2- [DNA] nucleobase degradation an N-terminal L- GDP molybdopterin) NAD geranyl glutathione hydroxyacyl-CoA anhydro-N-acetyl- diaminopimeloyl- γ GDP synthase: bioD dihydrofolate AzCIB_RS02530 selenouridine(34) octadecenoyl-CoA semialdehyde semialdehyde 3'-phosphate products] an octanoyl-[acp] (meso-DAP L-Ala- -D-Glu- met cysteinyl-[protein] glyoxylate pyruvate RS05240 3-methyl-2-oxobutanoate ribazoletransferase: diphosphate β reductase: cofactor [bis-MGD cofactor enoyl-CoA NAD-dependent -D-muramate D-alanine containing) DAP-D-Ala heme b biosynthesis II hydroxymethyltransferase: serine glycine cleavage α α synthase acetyl-CoA C- acetaldehyde AzCIB_RS15940 AzCIB_RS02530 Co -[ - chaperone]-S- chaperone]- bifunctional (p)ppGpp geranyl hydratase: adenosylcobinamide- dethiobiotin panB hydroxymethyltransferase:system protein MnmH: mnmH acyltransferase: dehydrogenase succinate- (oxygen-independent) a 7,8-dihydrofolate a 5-methyltetrahydrofolate (benzimidazolyl)]-Co sulfanyl-L-cysteine bis-MGD nucleoside- synthetase/guanosine- transferase: coenzyme A RS05430 GDP α α a 5-methylaminomethyl- AzCIB_RS10100 (acetylating): semialdehyde biotin AzCIB_RS10535 GcvH: gcvH Co -[ -(2- β-adenosylcobamide 5-methylbenzimidazole AzCIB_RS12425 a [ribosomal a 2-oxo a peptidoglycan L-alanyl-γ-D-glutamyl-L- a [protein]- (2Z)-2-hydroxyhexa- a mismatched queuosine at a peptide with 2-dehydropantoate adenosylcobinamide- diphosphate 3',5'-bis(diphosphate) 3'- AzCIB_RS16545 hydroxylamine [+ 2 isozymes] a 2,3,4-saturated a 2,3,4-saturated AzCIB_RS07490 ethanol dehydrogenase: succinate a sulfurated a [protein]-L-lysine (S)-2- aci-nitroethane an aromatic 5-MTR-1-P RS05270 ribazoletransferase: uroporphyrinogen-III [+ 2 isozymes] [+ 4 isozymes] methyladenin-9-yl)]-Co molybdenum cofactor biosynthesis 2-(S-geranyl) acetyl-CoA C- protein S12] carboxylate dimer (E. faeciums) lysyl-D-alanyl-D-alanine acyl-carrier protein L-glutamine glu 2,5-dienoate DNA base pair glu position 34 an N-terminal RS05260 synthase 5'-phosphate GDP ribotide phosphate kinase: pyrophosphohydrolase: 34 laurate AzCIB_RS02530 thymidylate β (2E,6E)-farnesyl thiouridine in tRNA fatty acyl CoA 3-oxoacyl-CoA AzCIB_RS13170 [sulfur carrier] 89 aminobutanoate Asp amino acid BioB: bioB uroporphyrinogen a (6S)-5-formyltetrahydrofolate -adenosylcobamide (S)-3-hydroxy-(9Z) acyltransferase: acetaldehyde L-aspartate 2-keto-4- DNA of a tRNA L-alanine S-methyl-5- 2-dehydropantoate 2- synthase: AzCIB_RS03550 AzCIB_RS10140 diphosphate aspartate/ decarboxylase: bifunctional 5'-phosphate tRNA 2- -octadecenoyl-CoA AzCIB_RS20990 dehydrogenase pentenoate mismatch thioribose-1- Coα-[α-(adenin-9-yl)]- reductase: AzCIB_RS09640 AzCIB_RS15935 sulfo-bis(guanylyl adenosylcobinamide- molybdate succinate penicillin-binding penicillin-binding transglutaminase: nitronate tyrosine/aromatic 9-mercaptodethiobiotin AzCIB_RS23425 methylenetetrahydrofolate5-formyltetrahydrofolate bifunctional (p)ppGpp selenouridine(34) (acetylating): 2-oxoacid:ferredoxin hydratase: repair protein phosphate β α α molybdopterin) acetone 30S ribosomal protein 2: mrdA bifunctional acyl- glutamate-- tRNA glutamyl- aminotransferase: aminopeptidase Co -adenosylcobamide coproporphyrinogen III β-alanine dehydrogenase/ cyclo-ligase: Co -[ - GDP synthetase/guanosine- di-trans,poly-cis- octaprenyl synthase oxidoreductase protein 2: mrdA AzCIB_RS19525 monooxygenase: RS10825 methylenetetrahydrofolate cofactor molybdopterin molybdenum ammonium degradation II AzCIB_RS22035 protein S12 ACP--phospholipid cysteine ligase: AzCIB_RS07485 MutS: mutS Q(34) synthetase isomerase: RS15650 5'-phosphate heme a biosynthesis biotin (R)-pantoate methenyltetrahydrofolate (benzimidazolyl)]-Co ribazoletransferase: 3',5'-bis(diphosphate) 3'- MnmH: mnmH subunit beta: D-alanyl-D-alanine D-alanyl-D-alanine transglutaminase AzCIB_RS07410 AzCIB_RS13945 N: pepN AzCIB_RS21325 α α ABC decaprenylcistransferase: diphosphate (to acetoacetate) AzCIB_RS17235 2-oxopent- DNA mismatch mtnA RS02425 synthase oxygen-independent reductase [NAD(P)H]: metF Co -[ -(2- β-adenosylcobamide AzCIB_RS02530 molybdopterin a 5-methylaminomethyl- 3-oxo-(9Z)- methylthiotransferase AzCIB_RS06265 carboxypeptidase/ O-acyltransferase/ domain-containing GluQRS: aspartate/ S-methyl-5- cyclohydrolase FolD: folD pyrophosphohydrolase: uppS synthase: ispB carboxypeptidase/ nitronate 4-enoate repair NAD salvage pathway I (PNC VI cycle) methyladenin-7-yl)]-Co adenylyltransferase: transporter 2-(Se-phospho) propan-2-ol acetyl-CoA creatinine RimO: rimO D-alanyl-D-alanine- long-chain-fatty- glutamate- AzCIB_RS02900 thio-D-ribulose BioB: bioB coproporphyrinogen pantoate--beta-alanine a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate glutathione AzCIB_RS01090 octadecenoyl-CoA acetyl-CoA [+ 2 isozymes] D-alanyl-D-alanine- protein: monooxygenase: tyrosine/aromatic protoheme β-adenosylcobamide Coα-[α-(5- ATP-binding 34 acid--ACP ligase: -cysteine hydratase: dmpE protein MutS: 1-phosphate III oxidase: hemN AzCIB_RS04440 di-trans,octa-cis all-trans- selenouridine in tRNA acetyl-CoA C- degradation I endopeptidase: dacB endopeptidase: dacB AzCIB_RS01025 AzCIB_RS21120 (S)-4-hydroxy- aminotransferase: Coα-[α-(adenin-7-yl)]- protoheme IX biotin ligase: AzCIB_RS17560 biosynthesis protein: modC bifunctional enoyl- AzCIB_RS23870 ala a peptide + bifunctional bis(guanylyl molybdenum methylbenzimidazolyl)]- molybdopterin -undecaprenyl octaprenyl tRNA 2- phenylethylamine a [ribosomal AzCIB_RS01010 ligase: gshA glutamyl- β farnesyltransferase: NAD tRNA processing acyltransferase: a reduced 2-oxohexanoate a properly matched AzCIB_RS03830 RS05400 Co -adenosylcobamide protoporphyrinogen IX methylenetetrahydrofolate Coβ-adenosylcobamide selenouridine(34) CoA hydratase/ degradation II 5'-deoxyadenosine an unsulfurated + an aromatic RS19765 S-adenosyl-L- cofactor) biosynthesis adenine GDP diphosphate diphosphate AzCIB_RS20990 creatinine met protein S12]-3- an acyl-CoA CO H a peptidoglycan tetramer queuosine at AzCIB_RS18500 molybdate acetone [sulfur carrier] 2 ferredoxin [iron- γ a protein with an DNA base pair (R)-pantothenate dehydrogenase/ methionine salvage II cys glu 5'-phosphate dinucleotide undecaprenyl- synthase phosphate methylsulfanyl- L-alanyl- -D-glutamyl- position 34 2-oxo-acid TorC ferroheme o MoO - acetyl-CoA C- creatininase: sulfur] cluster with a D,D cross-link D-ala N 6 -(γ-glutamyl)- γ-L-glutamyl-(S)- acetaldehyde nitrite NAD(+) 2 a polycistronic acetyltransferase: 2-phenylethylamine 89 L-lysyl-D-alanine D-ala Asp NAD+ synthase: methenyltetrahydrofolate diphosphate MnmH: mnmH acetone AzCIB_RS10600 L-aspartate (Enterococcus faecium) a dodecanoyl-[acp] of a tRNA diphosphatase: molybdopterin a 5-methylaminomethyl- tRNA precursor acyltransferase: L-lysine crosslink 2-aminobutanoate type III pantothenate AzCIB_RS15355 cyclohydrolase FolD: folD molybdopterin molybdopterin phosphatase: carboxylase: AzCIB_RS20780 quinohemoprotein NAD+ synthase: nudC SAH glutamate-- cofactor 34 AzCIB_RS12425 creatine glutathione- kinase: AzCIB_RS02835 α α 2-selenouridine amine RS05540 AzCIB_RS15355 10 Co -[ -(5- molybdotransferase AzCIB_RS19335 AzCIB_RS20000 phosphate glutaredoxin menaquinol-7 biosynthesis protoporphyrin IX an N -formyltetrahydrofolate adenosylhomocysteinase: cysteine ligase: di-trans,octa-cis in tRNA dehydrogenase: nicotinate adenine molybdenum cofactor methylbenzimidazolyl)]- MoeA: Storage Compound Biosynthesis Tetrapyrrole Biosynthesis (7Z)-hexadecenoyl-CoA AzCIB_RS20005 acetyltransferase: pta α RS10580 (R)-4'-phosphopantothenate NMN AzCIB_RS02275 AzCIB_RS17235 34 (E)-4-hydroxy-3- 5-deoxy- - redox reactions guanylyltransferase: β AzCIB_RS09175 -undecaprenyl peaD peaA a 5,10- a 2-thiouridine + a nucleoside ferroheme i all-trans- ferrochelatase: dinucleotide Co -adenosylcobamide 2-methylbutanoate acyl-carrier protein NADPH NAD a uracil in DNA γ-L-glutamyl-(S)- gly L-cysteate a glycyl-[tRNA Ala ] methylbut-2-en- γ-L-glutamyl- gly D-ribose 1- RS19660 folate polyglutamylation L-homocysteine glutamate- phosphate a tRNA precursor a tRNA precursor acyl-CoA acetoacetate acetyl phosphate phenylacetaldehyde methylenetetrahydrofolate in tRNA dGTP ATP 5-hexenoate triphosphate RNA glutathione heptaprenyl 1,4-dihydroxy- AzCIB_RS14980 mobA molybdopterin polyhydroxybutanoate biosynthesis siroheme biosynthesis Alcohol Degradation a tRNA precursor 2-aminobutanoate aspartate/ 1-yl diphosphate D-alanine phosphate nicotinate-nucleotide -cysteine Hormone Biosynthesis with a 5' flavodoxin- S-methyl-5- 2-naphthoate molybdotransferase with a 5' dehydrogenase: CTP diphosphate adenylyltransferase: ligase: gshA tyrosine/aromatic thioribose-1- protoheme methionine bis(molybdenum MoeA: extension and extension and a AzCIB_RS22980 acetate kinase: sarcosine tRNA uridine-5- acetate--CoA NAD(P)(+) uracil-DNA dependent a tetrahydrofolate cytidylyl molybdenum glycerol and glycerophosphodiester degradation DNA-directed glutathione aminotransferase: glutathione nadD synthase: metH acetyl-CoA uroporphyrinogen-III a long 3' trailer short 3' extension [+ 24 isozymes] AzCIB_RS11205 bifunctional acyl- transhydrogenase glycosylase: D-tyrosyl- (E)-4-hydroxy- phosphate a reduced 5,6-dimethylbenzimidazole cofactor sulfurylation cofactor) tetrahydrofolate salvage from AzCIB_RS04290 indole-3-acetate carboxymethylaminomethyl(34) deoxyguanosinetriphosphate ligase: acsA multifunctional AzCIB_RS13945 hydroxyferroheme i γ-L-glutamyl- uroporphyrinogen-III ribonuclease acetate/propionate ACP--phospholipid RNA polymerase synthase: tRNA(Tyr) 3-methylbut- synthase: isomerase: RS17195 glutaredoxin biosynthesis I (aerobic) molybdenum cofactor biosynthesis (2E,7Z)- phenylacetate synthesis enzyme MnmG: mnmG triphosphohydrolase: acetate--CoA (Re/Si-specific): AzCIB_RS06410 nicotinamide serine bifunctional L-cysteine 5,10-methenyltetrahydrofolate acetyl-CoA C- C-methyltransferase: P protein glycerol CCA addition/ O-acyltransferase/ subunit omega: gshB aspartate/ deacylase: 2-enyl- gshB mtnA RS19570 NaMN cytidylyl molybdenum met guanylyltransferase: MoO - VI (bacteria) hexadecenoyl-CoA family kinase: ligase: acs AzCIB_RS16620 5-deoxy-D- 2 acyltransferase: tRNA uridine-5- AzCIB_RS20800 repair protein: uracil-DNA AzCIB_RS01085 glutaredoxin hydroxymethyltransferase: tetrahydrofolate cofactor (trioxo) glutathione a 5,10- molybdopterin cobA ribonuclease PH: component: AzCIB_RS20785 long-chain-fatty- tyrosine/aromatic AzCIB_RS14590 diphosphate ribulose 1- demethylmenaquinol-7 riboflavin mobA AzCIB_RS12425 enoyl-CoA carboxymethylaminomethyl(34) AzCIB_RS16625 glycosylase: 3: grxC AzCIB_RS10535 synthase/ 10 AzCIB_RS21345 [+ 3 isozymes] aminotransferase: bifunctional riboflavin an N - methionine synthase: methenyltetrahydrofolate cofactor [+ 2 isozymes] trp AzCIB_RS21935 rnpA gly acid--ACP ligase: AzCIB_RS16630 2-C-methyl-D-synthase: ispG phosphate NAD bis(guanylyl bifunctional hydratase: acetate synthesis GTPase MnmE: mnmE (2S)-2- AzCIB_RS10025 ophthalmate norophthalmate glutathione- bifunctional [+ 2 isozymes] dihydrofolate formyltetrahydrofolate gshB [+ 3 isozymes] precorrin-1 a tRNA precursor AzCIB_RS01010 AzCIB_RS03830 erythritol-2,4- phosphorylation and kinase/FAD synthetase: nicotinate an [MCD cofactor adenosyltransferase: molybdopterin) methylenetetrahydrofolate AzCIB_RS10100 diphosphate dependent ferroheme a demethylmenaquinone synthase: folC a tRNA with a short 2'-deoxyguanosine triphosphate methylbutanoyl-CoA AMP a tRNA 3-sulfopyruvate a tRNA Ala gly cyclodiphosphate transhydrogenation AzCIB_RS16500 phosphoribosyltransferase: bifunctional chaperone]-MCD AzCIB_RS02300 cofactor dehydrogenase/ acetoacetyl-CoA [+ 2 isozymes] glycerol RS19585 disulfide-bond methyltransferase/2- a 5,10- glutathione uroporphyrinogen-III (indol-3- precursor with 3' extension a 5-aminomethyl-2- containing a + an apyrimidinic uracil RNA FMN AzCIB_RS13615 tetrahydrofolate cysteine a glycerophosphodiester a 7,8-dihydrofolate NADH NADP + methenyltetrahydrofolate yl)pyruvate 34 FliR oxidoreductase: methoxy-6-polyprenyl- NAD methylenetetrahydrofolate SAM bis(guanylyl tungstenpterin) C-methyltransferase: a 5' extension (S)-3-hydroxy-(7Z) thiouridine in tRNA 3' CCA end site in DNA nicotinate a tetrahydrofolate synthase/ desulfurase: cyclohydrolase FolD: folD acetoacetyl- a 5-hexenoyl-[acp] 1,4-benzoquinol 10 cobA indolepyruvate/ -hexadecenoyl-CoA glycerol yghU NAD kinase: bifunctional dihydrofolate an N - cofactor biosynthesis CoA ribonuclease PH: sufS [+ 2 isozymes] ribonuclease kinase glycerophosphodiester a protein with methylase UbiE: ubiE AzCIB_RS14970 tetrahydrofolate formyltetrahydrofolate reductase: phenylpyruvate AzCIB_RS21935 synthase: folC [+ 2 isozymes] guanylyl molybdenum GlpK: glpK reduced L- + decarboxylase: P protein phosphodiesterase: ugpQ NADP synthase/ 10 cofactor biosynthesis phosphoribosylglycinamide phbB menaquinol-7 FMNH menaquinol-9 biosynthesis an N - a [cytidylyl molybdenum GTP precorrin-2 component: a [dinitrogen DNA with adenine:7,8- a 2,3,4-saturated (24E)-3α,7α- (24R,25R)- an unstable FliM cysteine residues 2 dihydrofolate formyltransferase: bis(tungstenpterin) (3R)-3- ipdC a single + formyltetrahydrofolate cofactor chaperone]- MoO - 3-oxo-(7Z)- cob(II)inamide acetoacetate NAD a (6S)-5- oxaloacetate dihydro-8- dihydroxy-5β- α α α RecA filament- 2 rnpA sn-glycerol reductase]- glu 1,2-diacyl-sn 3 ,7 ,12 ,24- asp RS04620 menaquinol-6 biosynthesis NAD(P) synthase: folC menaquinol-8 biosynthesis AzCIB_RS17765 cofactor hydroxybutanoyl- poly-[(R)-3- (indol-3-yl) ATP stranded DNA ITP dGDP AMP 5,6-dimethylbenzimidazole cytidylyl molybdenum molybdopterin hexadecenoyl-CoA L-arginine formyltetrahydrofolate oxoguanine mismatch -glycerol 3- cholest-24-enoyl-CoA tetrahydroxy-5β- DNA complex transhydrogenase: demethylmenaquinol-9 CoA hydroxybutanoate] acetaldehyde 3-phosphate 3-alpha,7- aspartate/ DNA a 5,10- cofactor (sulfo-dioxo) cofactor acetyl-CoA C- CTP cholestanoyl 3-alpha,7-CoA adenosylcobalamin- pyrimidine 5'- AzCIB_RS16625 synthase: bluB bifunctional molybdopterin- a tetrahydrofolate molybdenum cofactor phosphate alpha, 12-alpha- tyrosine/aromatic repair demethylmenaquinol-6 methylenetetrahydrofolate demethylmenaquinol-8 acyltransferase: exodeoxyribonuclease acetoacetate--CoA NAD(+)--dinitrogen- alpha, 12-alpha- dependent nucleotidase: AzCIB_RS16630 demethylmenaquinone guanine guanylyltransferase: class I poly(R)- sirohydrochlorin cob(I)yrinic acid a,c-diamide bifunctional A/G-specific trihydroxy-5-beta- aminotransferase: protein bifunctional NADP 5,6-dimethylbenzimidazole bifunctional queuosine biosynthesis I (de novo) AzCIB_RS20990 VII large subunit: ligase: AzCIB_RS06500 reductase ADP-D- phosphoenolpyruvate trihydroxy-5-beta- ribonucleoside- AzCIB_RS04310 methyltransferase/2- dinucleotide mobA hydroxyalkanoic an uncharged adenosyltransferase: tetrahydrofolate adenine cholest-24-enoyl- AzCIB_RS13945 RecO: demethylmenaquinone biosynthesis NADPH demethylmenaquinone AzCIB_RS15640 acetoacetate--CoA cholest-24-enoyl- diphosphate 5'/3'-nucleotidase RS19545 biosynthesis acid synthase: sirohydrochlorin tRNA acetyl-CoA C- AzCIB_RS04470 ribosyltransferase: synthase/ carboxykinase (GTP) glycosylase: CoA hydratase: recO methoxy-6-polyprenyl- (indol-3-yl)acetate DHAP aspartate/ reductase: a stabilized RS13535 methyltransferase/2- methyltransferase/2- protein B: mobB chelatase: acyltransferase: exodeoxyribonuclease ligase: AzCIB_RS15790 AzCIB_RS03510 : AzCIB_RS02650 CoA hydratase: SurE: surE + 1,4-benzoquinol bis(guanylyl phaC preQ cob(I)yrinic acid a,c-diamide dihydrofolate mutY (24R,25R)-3α,7AzCIB_RS12375α,24- α α α RecA filament- methoxy-6-polyprenyl- NAD methoxy-6-polyprenyl- 0 VII small subunit: xseB (24E)-3 ,7 ,12AzCIB_RS12375- tyrosine/aromatic AzCIB_RS14795 methylase UbiE: ubiE guanylyl[+ 2 isozymes] tungstenpterin) cofactor AzCIB_RS20655 NADPH-dependent 7- AzCIB_RS12425 synthase: folC trihydroxy-5β- adenosine 1,4-benzoquinol NAD kinase: class I poly(R)- adenosyltransferase: cobO a [dinitrogen trihydroxy- aminotransferase: DNA complex 1,4-benzoquinol molybdenum cyano-7-deazaguanine Detoxification a CDP-2,3,4- GDP menaquinol-9 hydroxyalkanoic ω cholestanoyl CoA 5β-cholest- methylase UbiE: ubiE AzCIB_RS14970 methylase UbiE: ubiE siroheme (5Z)-tetradecenoyl-CoA acetoacetyl-CoA diphosphate reductase]-N -α- nicotinamide phosphoenolpyruvate an apurinic site saturated- AzCIB_RS03830 cofactor reductase QueF: queF lipoprotein posttranslational modification a ribonucleoside a single-stranded AMP + menaquinol-8 acid synthase: adenosylcobinamide ( ADP-D-ribosyl) a (6S)-5- IDP adenine within DNA 24-enoyl-CoA oxaloacetate menaquinol-6 NADP preQ reactive oxygen species degradation oligodeoxyribonucleotide diacylglycerol RS24260 phaC 1 triphosphate 5'-monophosphate acyl-CoA arsenate arsenate detoxification arsenate arginine -L-arginine formyltetrahydrofolate LolD a [prolipoprotein]- dehydrogenase: tRNA guanosine(34) detoxification II (glutaredoxin) detoxification V dependent poly-[(R)-3- L-cysteine AzCIB_RS07365 superoxide transglycosylase Tgt: tgt III (thioredoxin) acid resistance hydroxybutanoate] prolipoprotein [+ 24 isozymes] arsenate a [DNA]-3'- a 5'-phospho- a [protein] N-terminal- (2S)- a 1-acyl-2- a [protein]-L- superoxide arsenate arsenate pyruvate NAD + benzoyl-CoA H O gln a 7-aminomethyl-7- diacylglyceryl arsenate reductase cob(II)alamin H O methylsuccinyl- 2 carbonic acid glutaminyl-tRNA Aminoacyl-tRNA Charging (2E,5Z)- aldehyde arg ATP hydroxyl [DNA] DL-allothreonine 2 GTP formyl-L-methionine a type IV prepilin acetyl-CoA arachidonoyl- methionine tRNA charging deazaguanosine 34 in tRNA dismutase: arsenate ITP IMP MgtE biosynthesis via transamidation transferase: tetradecenoyl-CoA (glutaredoxin): arsC dehydrogenase: arginine/lysine/ CoA sn-glycerol peptide- AzCIB_RS15645 reductase RdgB/HAM1 family non- pyrimidine 5'- RarD tRNA preQ1(34) S- AzCIB_RS19615 arsenate reductase AzCIB_RS03080 ornithine 3-phosphate CTP methionine a [prolipoprotein]- (glutaredoxin) 1-arseno-3- pyruvate NAD- peptide benzoyl-CoA canonical purine NTP carbonic nucleotidase: adenosylmethionine enoyl-CoA hydrogen ArsC: AzCIB_RS05615 3-oxoadipyl- (S)-S-oxide glu Gln : arsC decarboxylase: cob(I)yrinic acid a,c-diamide dependent serine GTPase domain- prepilin peptidase: thioesterase: gln a tRNA ribosyltransferase- S-1,2-diacyl-sn- peroxide arsenite phosphoglycerate phosphate deformylase: def pyrophosphatase: rdgB anhydrase: AzCIB_RS04310 reductase Ala ser asp Phe hydratase: AzCIB_RS15945 adenosyltransferase: cobO hydroxymethyltransferase: CoA thiolase: a tRNA ala ser a tRNA tRNA asp phe a tRNA glyceryl-L-cysteine arsenite dikinase: DNA ligase containing protein: peptide AzCIB_RS18195 AzCIB_RS23025 AzCIB_RS15280 elongator isomerase QueA: queA AzCIB_RS03180 agmatine AzCIB_RS10535 AzCIB_RS09575 nucleotide 5'/3'-nucleotidase MsrA: msrA arg a tRNA Arg his a tRNA His pro a tRNA Pro tyr a tRNA Tyr val a tRNA Val glu a tRNA glu trp a tRNA Trp lys a tRNA Lys cys a tRNA Cys met initiator tRNA Met met leu a tRNA Leu ile a tRNA Ile thr a tRNA Thr gly a tRNA Gly (3E,5Z)-tetradeca- catalase/ cob(I)yrinic acid a,c-diamide AzCIB_RS21720 LigA: ligA AzCIB_RS11600 deformylase: prepilin peptidase: [+ 3 isozymes] a protein-L- tRNA Met arsenical arsenical pump- pyrophosphohydrolase: SurE: surE UbiB glutamine-- an epoxyqueuosine 34 in tRNA lipoprotein 3,5-dienoyl-CoA [+ 2 isozymes] peroxidase adenosyltransferase: [+ 2 isozymes] [+ 7 isozymes] AzCIB_RS14305 AzCIB_RS20520 [+ 2 isozymes] methionine- Asn pump-driving driving ATPase: arsA AzCIB_RS07710 inosine tRNA ligase/ alanine- serine- aspartate- phenylalanine- asn tRNA 1-arseno-3- AzCIB_RS04470 benzoate (S)-S-oxide FtsB gln signal peptidase: acyl-CoA HPI: katG phosphoenol an L-glutamyl- YqeY domain tRNA (S)-3-hydroxy-(5Z) ATPase: arsA phosphoglycerate + IMP a CDP-1-acyl- arginine-- histidine- -tRNA proline-- tyrosine-- valine-- glutamate-- tryptophan-- lysine- cysteine-- -tRNA methionine- methionine- leucine-- isoleucine- threonine- -tRNA -tRNA ligase: glycine--tRNA AzCIB_RS16510 thioesterase: H O hydroxyl radical arsenite diphosphate H [DNA] NMN + 4-methyl-3- CO H O Gln 2 AMP pyruvate AMP phosphate H a cleaved type 2-arachidonoyl- 2 2 [tRNA ] tRNA ligase: fusion protein: -tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: -tRNA -tRNA -tRNA tRNA ligase: -tRNA -tRNA AzCIB_RS17935 ligase: glyQ epoxyqueuosine(34) -tetradecenoyl-CoA acetaldehyde GDP an N-terminal L- Asp-tRNA(Asn) tRNA ligase: tRNA ligase: tRNA ligase: ligase: ligase: AzCIB_RS08770 arsenite adenosylcobalamin gly formate a peptide oxoadipyl-CoA AzCIB_RS02700 reductase QueG: queG an (S-diacyl-sn- O triphosphate methionyl-[protein] IV prepilin glycerol Asp-tRNA(Asn) AzCIB_RS02040 ligase: hisS alaS AzCIB_RS04595 AzCIB_RS04660 AzCIB_RS05550 AzCIB_RS07940 AzCIB_RS12995 ligase: lysS AzCIB_RS15010 serS ligase: metG ligase: metG AzCIB_RS16045 ligase: ileS ligase: thrS aspS pheS AzCIB_RS03150 a lipoprotein [+ 4 isozymes] 2 /Glu-tRNA(Gln) glyceryl)-L-cysteinyl- /Glu-tRNA(Gln) a queuosine 34 in tRNA signal peptide (3E,5Z)- LeuE amidotransferase: an L-methionyl- [apolipoprotein] gatB gatA gatC amidotransferase: an L-arginyl- an L-glutaminyl- an L-histidyl- an L-alanyl- an L-prolyl- an L-tyrosyl- an L-valyl- an L-glutamyl- an L-tryptophanyl- an L-lysyl- an L-cysteinyl- an L-seryl- an L-methionyl- an L-leucyl- an L-isoleucyl- an L-threonyl- an L-aspartyl- an L-phenylalanyl- an L-asparaginyl- signal peptide tetradecadienoate RS14290 [elongator a glycyl-[tRNA Gly ] 3-oxo-(5Z)- gatB gatA gatC [tRNA Arg ] [tRNA Gln ] [tRNA His ] [tRNA Ala ] [tRNA Pro ] [tRNA Tyr ] [tRNA Val ] [tRNA Glu ] [tRNA Trp ] [tRNA Lys ] [tRNA Cys ] [tRNA ser ] [initiator tRNA Met ] [tRNA Leu ] [tRNA Ile ] [tRNA Thr ] [tRNA asp ] [tRNA Phe ] [tRNA Asn ] apolipoprotein N- peptidase UDP-N-acetyl-α-D-muramoyl- (1S,2R)-1- N-acetyl-β-D- 3''-O-acetyl- [+ 6 isozymes] Met tetradecenoyl-CoA 37 + 4-nitrophenyl (3E)-5-chloro-2- a 5-phosphooxy- tRNA ] di-trans,octa-cis- MoO - 2-oxoglutarate 1-methyl-dAMP an adenosine ammonium NAD H O 3',5'-ADP acyltransferase: lnt SppA: sppA L-alanyl-γ-D-glutamyl-L- ala a pimeloyl-[acp] 2 ser C-(indol-3- DMAPP glucosaminyl-(1 2 ADP-ribose ser acetyl-CoA C- undecaprenyl phosphate GTP in tRNA palmitate oxopent-3-enoate ATP ammonium L-glutamyl- an N-acyl-(S-diacyl- Inorganic Nutrient Metabolism lysyl-D-alanyl-D-alanine molybdopterin molybdopterin yl)glycerol -> 4)-N-acetyl- 2-keto-4- RNA 3'(2'),5'- Gln Fatty Acid and Lipid Biosynthesis acyltransferase: L-serine [tRNA ] sn-glyceryl)-L- a peptide cofactor 3-phosphate β-D-muramate pentenoate bisphosphate AzCIB_RS12425 DNA oxidative nitrite O-acetyl- ammonia-lyase: RS01920 cysteinyl-[lipoprotein] selenate reduction phospho-N- 8-amino-7- tRNA (adenosine(37)-N6) arylesterase: hydratase: ADP-ribose nucleotidase Asp-tRNA(Asn) palmitate biosynthesis (type II fatty acid synthase) acetyl-CoA C- nitrate reduction V (assimilatory) assimilatory assimilatory thiosulfate oxidation III (multienzyme complex) demethylase reductase AzCIB_RS05835 RS14140 acetylmuramoyl- oxononanoate molybdenum cofactor tryptophan -dimethylallyltransferase beta-N- AzCIB_RS13125 AzCIB_RS07485 polynucleotide deacetylase: CysQ: cysQ /Glu-tRNA(Gln) superpathway of lipopolysaccharide biosynthesis octanoyl-[acyl-carrier gondoate biosynthesis phosphatidylserine and acyltransferase: sulfate reduction IV sulfate reduction III AlkB: alkB small subunit L-serine (anaerobic) pentapeptide- synthase: bioF guanylyltransferase: synthase: MiaA: miaA acetylhexosaminidase: 2-oxopent- adenylyltransferase AzCIB_RS01740 amidotransferase: protein] biosynthesis phosphatidylethanolamine AzCIB_RS20990 selenate NirD: nirD ammonia-lyase: AMP gluconeogenesis I Carbohydrate Biosynthesis nitrate a [SoxY protein]-L-cysteine transferase: mobA AzCIB_RS15070 nagZ 4-enoate PcnB: pcnB gatB gatA gatC GDP-mannose biosynthesis an acetoacetyl-[acp] (mitochondria, yeast) biosynthesis I sulfate sulfate sulfate AzCIB_RS10530 α a (3R)-3- (3Z)-dodec- trpB 6 UDP-N-acetyl-D- UDP- -D-glucose periplasmic disulfide bond formation AzCIB_RS18940 formaldehyde succinate N -(3-methylbut- 4-nitrophenol palmitate hydratase: dmpE Amine and Polyamine Biosynthesis hydroxytetradecanoyl-[acp] UDP-N-acetyl- a malonyl-[acp] an oleoyl-[acp] a CDP-diacylglycerol adenylyltransferase: respiratory sulfate sulfate (8S)-8-amino-7- pyruvate glucosamine biosynthesis I biosynthesis α 3-enoyl-CoA bis(guanylyl dAMP 2-en-1-yl)- 5-chloro-4-hydroxy- acetate ADP-D-ribose RS09410 (S)-malate D-glucopyranose 3-oxoacyl-ACP -D-glucosamine an acetoacetyl-[acp] two reduced cysN cysD adenylyltransferase: adenylyltransferase: oxononanoate acyl-carrier protein D-glyceraldehyde N-acetyl-D- nitrite an L-glutaminyl- a [DsbB protein] a [DsbA protein] nitrate reductase: 37 GlcNAc 2-oxopentanoate RNA RsxC D-glucopyranose D-glucopyranose reductase 3-oxoacyl-ACP an electron- undecaprenyl-diphospho-N- molybdopterin) adenosine muramate Gln 6-phosphate cysteine residues cysN cysD cysN cysD UMP 3-phosphate trp [tRNA ] glucose-6- spermidine biosynthesis III with reduced L- carrying a sulfate AzCIB_RS10765 cofactor in tRNA 6-phosphate 6-phosphate FabG: fabG acyl-ACP--UDP-N- reductase beta-ketoacyl- a 3-sn-phosphatidyl- transfer quinone a [SoxY protein]-S- acetylmuramoyl-L-alanyl-γ-D- glucose-6- phosphate phosphomannomutase/ spermidine biosynthesis I putrescine cysteine residues disulfide bond in a protein adenylyltransferase: narH narI sulfate sulfate malate [+ 2 isozymes] acetylglucosamine O- FabG: fabG ACP synthase sulfosulfanyl-L-cysteine glutamyl-L-lysyl- D-alanyl-D-alanine phosphate phosphoglucomutase: biosynthesis III cadaverine L-serine (2E)-dodec- cysD cysN adenylyltransferase: adenylyltransferase: dehydrogenase: isomerase: acyltransferase: lpxA [+ 2 isozymes] II: fabF adenosine 5'- nitrite arg biosynthesis a (3R)-3- a (3R)-3- phosphatidylserine 2-enoyl-CoA cysD cysN cysD cysN AzCIB_RS09250 isomerase: AzCIB_RS06320 α-D-glucopyranoseAzCIB_RS04480 SAM phosphoselenate cytochrome c: APS α ADP-L-glycero-β- α-Kdo-(2->4)- a thiocarboxylated cyclic 2251 2''-O-acetyl- a protein-L- RS09330 AzCIB_RS06320 F6P arg hydroxybutanoyl-[acp] UDP-3-O-[(3R)-3- hydroxybutanoyl-[acp] decarboxylase: enoyl-CoA APS UDP-N-acetyl- -D- D-threo-7,8- a 2-oxo a peptide with guanosine 1-phosphate AzCIB_RS14220 di-trans,octa-cis- α 2-oxoglutarate 1-methyl-dATP N-formyl- acetyl-CoA SecA xanthan biosynthesis F6P SAM an (11Z)-3-oxo- AzCIB_RS17610 hydratase: muramoyl-L-alanyl-γ-D- D-manno-heptose -Kdo-(2->6)- [SAMP] C- pyranopterin carboxylate L-ornithine a PII protein an N-terminal in 23S rRNA L-ornithine ADP-ribose methionine- pyruvate arginine/lysine/ arginase: lys 3-hydroxyacyl- hydroxymyristoyl]-N- 3-hydroxyacyl- [+ 9 isozymes] undecaprenyl phosphate dihydroneopterin L-glutamate oxaloacetate mannose-1-phosphate UTP--glucose- adenylyl-sulfate phosphoadenylyl- glutamyl-L-lysyl-D-alanine lipid IV (E. coli) terminal glycine phosphate UTP L-proline 23S rRNA acetyl-CoA (R)-S-oxide ornithine α icos-11-enoyl-[acp] AzCIB_RS10100 A peptide- rocF arginine/lysine/ ACP dehydratase acetyl- -D-glucosamine ACP dehydratase an L-1- sulfate reductase: arginine N- α glutamine-- guanylyltransferase/ 1-phosphate decarboxylase: UDP-3-O-acyl-N- kinase: cysN a [SoxY protein]-S- a [SoxY protein]-S (guanosine(2251) O-acetyl- carboxylase methionine UDP- -D-glucose L-ornithine ornithine FabZ: fabZ FabZ: fabZ beta-ketoacyl- phosphatidylethanolamine [+ 2 isozymes] selenite ammonium AzCIB_RS21105 lipopolysaccharide DNA oxidative dihydroneopterin succinyltransferase: phosphoenolpyruvate fructose-6- mannose-6- uridylyltransferase acetylglucosamine disulfanyl-L-cysteine -sulfanyl-L-cysteine phospho-N- ornithine- [protein-PII] -2'-O)- N-formylglutamate biotin a reduced AzCIB_RS15945 decarboxylase: ACP (S)-3- molybdopterin demethylase aldolase: prolyl AzCIB_RS05285 ADP-ribose (R)-S-oxide synthase: ppsA undecaprenyl- phosphate phosphate isomerase: GalU: galU putrescine dAdoMet PAPS heptosyltransferase -oxo-acid methyltransferase carboxylase H O c-type deacetylase: acetylmuramoyl- synthase uridylyltransferase: amidohydrolase: reductase 2 AzCIB_RS15945 a (2E)-but-2-enoyl-[acp] a (2E)-but-2-enoyl-[acp] reductase: phbB hydroxydodecanoyl-CoA sulfite AlkB: alkB AzCIB_RS16085 aminopeptidase: pip arginine N- deacetylase: cytochrome phosphate glucose transaminase AzCIB_RS15260 agmatine dAdoMet arginine/lysine/ AzCIB_RS18895 type I glutamate I: waaC transaminase: RlmB: rlmB AzCIB_RS11075 subunit: accC cytochrome UDP-α-D-glucose cadaverine [+ 2 isozymes] phosphoadenylyl- pentapeptide- catalytic subunit AzCIB_RS10995 2-O- AzCIB_RS01740 MsrB: msrB an oxidized YajC phosphoenol phosphotransferase: (isomerizing) ornithine UDP-3-O-(3- assimilatory sulfite dihydroneopterin rocD succinyltransferase: a [protein]-L- c oxidase mannose-1-phosphate spermidine synthase: enoyl-ACP acyl-CoA/acyl-ACP glutamate- synthase sulfate reductase: transferase: heptosyl- MoaE: moaE methylguanosine 2251 [+ 4 isozymes] O c-type pyruvate decarboxylase: long-chain fatty AzCIB_RS05290 2 AzCIB_RS04040 : glmS hydroxymyristoyl) a (3R,11Z)-3-hydroxy- reductase (NADPH) aldolase: folB 2 methionine guanylyltransferase/ polyamine AzCIB_RS10625 reductase dehydrogenase: acid activation DsbA family selenodiglutathione -ammonia subunit AzCIB_RS21105 AzCIB_RS18940 Kdo -lipid IV formaldehyde succinate in 23S rRNA N -succinyl- malonyl-CoA a cytochromereduced phosphopyruvate α AzCIB_RS15945 α icos-11-enoyl-[acp] ADP 2 A a uridylylated -D-glucopyranosyl- D-glucosamine mannose-6- aminopropyltransferase: polyamine FabI: fabI - -D-glucosamine AzCIB_RS12365 oxidoreductase: ligase: glnA beta: gltD : AzCIB_RS21095 dATP a proteinogenic L-glutamate-5- a peptide pro L-ornithine formate glu acetate ADP-D-ribose H O c-type UDP-3-O-(3- 3-oxododecanoyl-CoA a [SoxY protein]-S-(2- a [SAMP] C- 2 hydratase: diphosphoundecaprenol 6-phosphate 3-hydroxyacyl- a long-chain AzCIB_RS01050 sulfite undecaprenyl-diphospho-N molybdopterin 6-(hydroxymethyl) semialdehyde PII protein cytochrome phosphate isomerase: speE aminopropyltransferase: putrescine [+ 3 isozymes] a [DsbB protein] a [DsbA protein] NADP-specific hydrogen sulfide sulfodisulfanyl)-L-cysteine UMP terminal glycine glycolaldehyde amino acid RS06565 an oxidized AzCIB_RS09755 PRPP biosynthesis a butanoyl-[acp] hydroxymyristoyl) fatty acid an electron- an intra- γ phosphoglucosamine AzCIB_RS19190 speE ACP dehydratase long-chain fatty carrying a with reduced L- acetyl-CoA C- glutamate -acetylmuramoyl-L-alanyl- - -7,8-dihydropterin O c-type 2 RS18755 2-phospho- 1 glucosamine N- a butanoyl-[acp] transfer quinol protein disulfide gln mutase: glmM D-mannopyranose N -(3-aminopropyl) FabZ: fabZ acid--CoA ligase: disulfide bond cysteine residues acyltransferase: dehydrogenase: D-glutamyl-L-lysyl- D-alanine cytochromea reduced D-glycerate D-ribose 5- beta-ketoacyl- acyltransferase: urea cycle β-D-glucosyl-(1,4)-α-D-glucosyl- α 6-phosphate agmatine AzCIB_RS08795 AzCIB_RS20990 glutathioselenol AzCIB_RS20390 H O c-type GDP-α-D-mannose -D-glucosamine phosphate spermidine ACP synthase lpxD beta-ketoacyl- a (2E,11Z)-icosa- 2 cytochrome 2,3-bisphosphoglycerate- β ribose-phosphate 6 cytochrome diphosphoundecaprenol 1-phosphate ADP-L-glycero- - phosphomannomutase/ UDP-2-N,3-O-bis[(3R)- 2,11-dienoyl-[acp] [+ 7 isozymes] acetyl-CoA C- hydrogen sulfide sulfoacetaldehyde degradation I N -(3-methylbut- 32 an [L-cysteine a peptidoglycan an [amino-group carrier L-fuculose an oxidized II: fabF ACP synthase a long-chain a cytosine + an (S)-2- c oxidase independent D-manno-heptose pyrophosphokinase: prs acyltransferase: a 5-L-glutamyl- H hydrogencarbonate a peptide with a citrate protein]-C-terminal-γ- Ins(1)P Ap4A a protein with UDP-N- phosphoglucomutase: 3-hydroxytetradecanoyl]- arg a sulfurated [sulfur carrier] 2-en-1-yl)- an amino acid in tRNA desulfurase]-S- halocarboxylate dimer (generic) 1-phosphate a protein O c-type II: fabF enoyl-ACP fatty acyl-CoA 6 37 glu [peptide] leader sequence a disulfide bond 2 phosphoglycerate biosynthesis ribose-phosphate α N -L-threonylcarbamoyladenosine AzCIB_RS12425 adenosine 37 in tRNA sulfanyl-L-cysteine aconitate hydratase (L-glutamyl)-L-glutamate symmetrical a reduced acetylglucosamine AzCIB_RS04480 a 3-oxohexanoyl-[acp] -D-glucosamine reductase sulfoacetaldehyde inositol ATP-dependent protein- cytochrome LptB mutase: D-sedoheptulose α pyrophosphokinase: prs spermidine -modified tRNA biosynthesis AcnA: acnA H O c-type -D-mannose D-ribulose 5-phosphate UDP-2,3- a 3-oxohexanoyl-[acp] hydrogen selenide ammonium acetylglutamate monophosphatase: Clp: clpX clpP bis(5'-nucleosyl)- disulfide 2 cytochrome- AzCIB_RS22880 α β diphosphorylase/ 7-phosphate FabI: fabI decanoyl-CoA carbonic haloacid endolytic fuculose -D-Man-(1->3)- -D-Glc- phosphoheptose 1-phosphate PRPP 3-oxoacyl-ACP argininosuccinate tRNA 2- bifunctional kinase: argB tetraphosphatase: c oxidase, cytochrome α glucosamine-1- diacylglucosamine tRNA (N6-isopentenyl gamma- anhydrase: transglycosylase AzCIB_RS13735 phosphate ATP-dependent reductase an oxidized 3-phospho- (1->4)- -D-Glc-1-diphospho- 3-oxoacyl-ACP nitrogen fixation lyase: argH arginase: sulfoacetaldehyde thiocytidine(32) dehalogenase aconitate hydratase AzCIB_RS19085 α phosphate N- isomerase: mannose-1-phosphate reductase diphosphatase: a gondoyl-[acp] thr acyl-CoA glutamine- adenosine(37)-C2)- MltG: mltG an [amino-group carrier inositol Clp protease a protein withDsbD: dsbD O cbb3-type c-type ditrans,octacis-undecaprenol UDP- -D-glucuronate rocF glutamyltransferase: ggt AzCIB_RS15280 type II: aldolase: 2 D-glycerate AzCIB_RS18995 FabG: fabG reductase dehydrogenase: I (ferredoxin) acetyltransferase: xsc synthetase 2/2-methylisocitrate protein]-C-terminal- acetyltransferase: D-glycero-D- guanylyltransferase/ AzCIB_RS17215 threonylcarbamoyl- polyphosphate metabolism hydrolyzing methylthiotransferase AzCIB_RS16280 [+ 6 isozymes] monophosphatase: AzCIB_RS19880 ATP-binding reduced L- cytochrome FabG: fabG TtcA: ttcA [+ 3 isozymes] dehydratase: γ ADP phosphoglycerate glmU manno-heptose mannose-6- [+ 2 isozymes] aldehydo-D-arabinose UDP-2,3- AMP synthase: AzCIB_RS22980 carbamoyl- MiaB: miaB -(5-phospho-L- AzCIB_RS04250 subunit ClpA: clpA cysteine residues RS04115 N L-arginino- an α-(5-L- [+ 3 isozymes] AzCIB_RS14480 CysW kinase: pgk N-acetyl-α-D- 7-phosphate phosphate isomerase: 5-phosphate diacylglucosamine [+ 2 isozymes] AzCIB_RS13005 [+ 24 isozymes] 2 L-ornithine phosphate sulfite glutamyl)-L-glutamate myo-inositol a (3R)-3- long chain nitrogenase succinate acetyl phosphate 32 an [L-cysteine GlcNAc-1,6- a peptide α 6 glutamyl)- a peptide a 2-thiocytosine a lipid II a leader sequence a peptide β-D-GlcA-(1->2)-α-D-Man- glucosamine D-glycero- AzCIB_RS15260 UDP- -D- hydroxyhexanoyl-[acp] diphosphatase: a (3R)-3- threonylcarbamoyl- polyphosphate synthase: N -(3-methylbut-2-en- CO H O anhydro-MurNAc- D-threo-isocitrate DHAP (S)-lactaldehyde (2E)-dec-2-enoyl-CoA molybdenum- amino acid desulfurase]- 2 2 13-DPG β 1-phosphate beta-D- galactose AzCIB_RS15035 hydroxyhexanoyl-[acp] AMP synthase: carB carA 5'-deoxyadenosine 1-yl)-2-(methylsulfanyl) an unsulfurated in tRNA a (2R)-2- (1->3)- -D-Glc-(1->4)- mannose-1-phosphate 3-hydroxyacyl- iron protein bifunctional enoyl-CoA met L-cysteine a halide anion pentapeptide α manno- biosynthesis AzCIB_RS04970 adenosine 37 in tRNA [sulfur carrier] hydroxy fatty acid -D-Glc-1-diphospho- UDP-N- guanylyltransferase/ ACP dehydratase 3-hydroxyacyl- (L-threonylcarbamoyl) enoyl-CoA subunit carbamoyl hydratase/phosphate type I heptose-7- D-arabinofuranose lipid X ditrans,octacis-undecaprenol acetylglucosamine UDP-α-D-glucose ACP dehydratase adenylate hydratase: polyphosphate beta: nifK argininosuccinate phosphate acetyltransferase: RS18665 RS19730 glyceraldehyde- GDP-mannose:glycolipid mannose-6- FabZ: fabZ 5-phosphate biotin-carboxyl carrier exopolyphosphatase: ppx ornithine RS19735 diphosphorylase/ phosphate UDP-glucose AzCIB_RS10100 kinase 1: ppk1 AzCIB_RS20780 TolR phosphate isomerase: lipid-A- FabZ: fabZ protein assembly tRNA (adenosine(37)-N6)- [+ 2 isozymes] synthase: carbamoyltransferase: a nascent peptidoglycan a 2'- D-sedoheptulose a double (3R,5S)-3- 3-phosphate 4-beta-D- kinase: rfaE1 3-deoxy-8- 1 an (R)-2- a reduced trimethylamine a ribonucleoside an unfolded glucosamine-1- β AzCIB_RS19190 4-epimerase a (2E)-hex-2-enoyl-[acp] disaccharide [+ 2 isozymes] ammonium AzCIB_RS15560 argF phosphate 3-methylbutanoate 2-oxoglutarate N -methyladenine deoxyribonucleoside carbamoyl L-ornithine asp O-ureido-L- Ins(2)P 1,7-bisphosphate hydroxy-1- dehydrogenase: mannosyltransferase: D-glycero- -D- phosphooctulonate threonylcarbamoyltransferase (meso-DAP containing) halocarboxylate [DNA] N-oxide 5'-monophosphate stranded DNA phosphate N- α GalE: galE synthase: lpxB a (2E)-hex-2-enoyl-[acp] a [biotin carboxyl- N-end rule pathway I (prokaryotic) L-citrulline acetyltransferase: pta 5'-triphosphate phosphate TorC protein homoserine protein gap AzCIB_RS04120 manno-heptose GDP- -D- synthase: kdsA complex dimerization (S)-3- 5'/3'-nucleotidase inositol DNA pyrroline-5- β β acetyltransferase: UDP-α-D-galactose enoyl-ACP carrier protein]-L-lysine D-Man- -(1->4)-GlcA- -(1->2) 1,7-bisphosphate mannose subunit type 1 TsaB: tsaB hydroxydecanoyl-CoA long chain thiosulfate monophosphatase: topoisomerase carboxylatepyrroline-5- aldehyde reductase lipid A disaccharide (E. coli) acyl-CoA/acyl-ACP leucyl/phenylalanyl- acetyl-CoA endolytic DNA oxidative HAD family SurE: surE fructose- chaperonin -D-Man-α-(1->3)-D-Glc-β- glmU KDO-8P biotin--[acetyl- polyphosphate acetate--CoA ligase: acsA (ATP- carboxylate RS04750 D-glycero- dehydrogenase: [+ 2 isozymes] tRNA--protein disproportionation transglycosylase demethylase DNA polymerase ornithine argininosuccinate pyrimidine 5'- AzCIB_RS13735 GroEL: groL RS21260 RS19740 triose-phosphate dehydrogenase: α UDP-N-acetyl- FabI: fabI CoA-carboxylase] 6 hydrolase: bisphosphate (1->4)-D-Glc- -1-diphospho- beta-D-manno- tetraacyldisaccharide an N -L- IV (rhodanese) acetate--CoA ligase: acs III subunit chi: carbamoyltransferase: synthase: hydrolyzing) reductase: RS01390 isomerase: AzCIB_RS03080 α AzCIB_RS12365 ligase: transferase: MltG: mltG AlkB: alkB AzCIB_RS17530 nucleotidase: inositol aldolase class II: ditrans,octacis-undecaprenol -D-glucosamine 4'-kinase: threonylcarbamoyladenine 37 a [protein] AzCIB_RS05560 argF AzCIB_RS15560 subunit B: gyrB AzCIB_RS19460 AzCIB_RS14885 heptose 1,7- a hexanoyl-[acp] AzCIB_RS09295 thiosulfate sulfide oxidation II [+ 5 isozymes] AzCIB_RS04310 monophosphatase: AzCIB_RS04200 a protein D-glyceraldehyde [+ 3 isozymes] AzCIB_RS02840 an N-terminal [+ 2 isozymes] Hyp DHAP bisphosphate 7- AzCIB_RS15625 a [biotin carboxyl- in tRNA N-terminal L- 3-oxodecanoyl-CoA (flavocytochrome c) [+ 7 isozymes] a ribonucleoside AzCIB_RS04250 [+ 2 isozymes] 3-phosphate dTDP-β-L-rhamnose arginyl-[protein] a negatively phosphatase: beta-ketoacyl- carrier protein]-N leucyl-L-arginine 3-methylbutanoyl-CoA diphosphate formaldehyde succinate biosynthesis α-Kdo lipid IV (E. coli) a hexanoyl-[acp] a mature peptidoglycan a nascent peptidoglycan AMP an oxidized trimethylamine myo-inositol D-erythrose supercoiled DNA D-Man-β-(1->4)-GlcA-β-(1->2)-6- gmhB A 6 fatty acid rhodanese: hydrogen sulfide adenine an (S)-2- canavaninosuccinate β ACP synthase -biotinyl-L-lysine with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) a halide anion L-citrulline TorC protein DHAP 4-phosphate RS13540 RS21555 O-acetyl-D-Man-α-(1->3)-D-Glc- D-glycero- -D- α-D-glucopyranose beta-ketoacyl- leucyl/phenylalanyl- oxidation AzCIB_RS21785 hydroxycarboxylate [DNA] RS09795 AdeC II: fabF 3-deoxy-manno- 3-deoxy-D-manno- flavocytochrome meso-2,6-diaminopimeloyl- with GlcNAc terminus β α manno-heptose ACP synthase tRNA--protein complex fructose- -(1->4)-D-Glc- -1-diphospho- 1-phosphate octulosonate octulosonic acid C: AzCIB_RS16365 D-alanine) tetrapeptide 1-phosphate glucose-1-phosphate subunit alpha bisphosphate ditrans,octacis-undecaprenol a 3-oxooctanoyl-[acp] cytidylyltransferase: transferase: II: fabF Glycolysis transferase: thiocyanate sulfite S 0 thymidylyltransferase a [biotin carboxyl- a [protein] FadB: fadB C1 Compound Utilization and Assimilation aldolase class II: D-glycero-beta-D- kdsB AzCIB_RS19210 an N-terminal AzCIB_RS09295 34 a 2'- a 2,3,4- AzCIB_RS04200 manno-heptose RfbA: rfbA 3-oxoacyl-ACP a 3-oxooctanoyl-[acp] carrier-protein dimer]- N-terminal L- [+ 2 isozymes] a [protein]-S- a uridine a peptide with trimethylamine a supercoiled 4-nitrophenyl D-sedoheptulose α α 6 L-lysyl-[protein] an apo [peptidyl- an acyl-[acyl- dTDP- -D-glucose -Kdo-(2->6)- N -biotinyl-L-lysine glycolysis III (from glucose) leucyl-L-lysine tyr SAM ARP coenzyme A deoxyribonucleoside an N-terminal a reduced RNA phenyl acetate saturated (3R)-3- 1-phosphate reductase CMP-Kdo formaldehyde oxidation carrier protein] sulfanyl-L-cysteine in tRNA [DNA] N-oxide duplex DNA butanoate 1-phosphate GTP RS13450 porin Pal lipid IV (E. coli) octanoyl-CoA formaldehyde oxidation formate carrier protein] 5'-triphosphate TorY protein ATP-dependent hydroxyacyl-CoA FlhB 4,6-CH3(COO-)C-D-Man-β- 6-O-acetyl-β-D-mannosyl-(1,4) adenylyltransferase: dTDP-glucose 4,6- FabG: fabG A 3-oxoacyl-ACP acetyl-CoA VII (THF pathway) Xaa-L-proline acetoacetyl- reductase carboxylase Aldehyde Degradation II (glutathione-dependent) oxidation to CO DNA helicase: (1->4)-GlcA-β-(1->2)-6-O- -β-D-glucoronate-(1,2)-α-N- rfaE2 dehydratase: rfbB [+ 2 isozymes] D-glucopyranose 2 diguanylate CoA β-D-fructose 1,6- acyl-CoA holo-ACP tRNA 2- AzCIB_RS09190 fructose- acetyl-D-Man-α-(1->3)-D-Glc- acetyl-D-mannosyl-(1,3)-β-D- ADP-D-glycero-β- dTDP-4-dehydro-6- FabG: fabG biotin formaldehyde 5-amino-6-(D-ribitylamino) phosphate DNA polymerase leucyl ribonuclease PH: arylesterase: arylesterase: cyclase: bisphosphate a (3R)-3- acetyl-CoA dehydrogenase: formaldehyde formate thiouridine(34) bisphosphate reductase: β α α α [+ 2 isozymes] carboxylase glucokinase: synthase: AzCIB_RS21935 DNA helicase AzCIB_RS13125 AzCIB_RS13125 AzCIB_RS10330 -(1->4)-D-Glc- -1-diphospho- glucosyl-(1,4)- -D-glucosyl- D-manno-heptose deoxy- -D-glucopyranose AzCIB_RS22980 methylglyoxal degradation I uracil--L-tyrosine acyltransferase synthase III subunit chi: aminopeptidase: aldolase class II: phbB class 1 fructose- hydroxyoctanoyl-[acp] carboxylase subunit: accC AzCIB_RS06505 formate AzCIB_RS13790 RecQ: recQ a 2,3,4-saturated ditrans,octacis-undecaprenol diphosphoundecaprenol ADP- dTDP-4- a (3R)-3- 4-hydroxyphenyl PlsX: plsX MnmA: mnmA AzCIB_RS05560 AzCIB_RS05565 AzCIB_RS04200 [+ 5 isozymes] RS08720 bisphosphatase: carboxyltransferase D-glucopyranose [+ 24 isozymes] a 5,10- dehydrogenase c-di-GMP 3-oxoacyl-CoA LapB RS18105 glyceromanno- dehydrorhamnose 3-hydroxyacyl- hydroxyoctanoyl-[acp] acetyl-CoA S-(hydroxymethyl) transferase CofH: cofH [+ 7 isozymes] a single stranded DNA CcmE AzCIB_RS03790 subunit beta: 6-phosphate Respiration methylglyoxal methylenetetrahydrofolate subunit gamma: a nucleoside heptose 6- 3,5-epimerase: rfbC ACP dehydratase carboxylase 2-oxoglutarate decarboxylation to succinyl-CoA (2E)-oct-2-enoyl-CoA glutathione a holo [peptidyl- a peptide with RNA butanoate 4-nitrophenol acetate phenol 3-hydroxyacyl- AzCIB_RS15065 lactoylglutathione AzCIB_RS00300 3',5'-ADP 34 an oxidized trimethylamine diphosphate dTDP-4-dehydro- FabZ: fabZ α α biotin glucose-6- bifunctional carrier protein] an acyl phosphate a [protein]- a 2-thiouridine a proteinogenic D-erythrose F6P epimerase: rfaD -Kdo-(2->4)- -Kdo- ACP dehydratase a [2-oxoglutarate lyase: S-(hydroxymethyl) CO 5-amino-5-(4-hydroxybenzyl)-6- acyl-carrier protein an N-terminal TorY protein DHAP enoyl-CoA methylenetetrahydrofolate 2 L-cysteine in tRNA amino acid ADP-L-glycero-β- β-L-rhamnose (2->6)-lipid IV (E. coli) carboxylase phosphate 5'-deoxyadenosine 2-iminoacetate met [DNA] L-proline xanthan a (2E)-oct-2-enoyl-[acp] A FabZ: fabZ dehydrogenase AzCIB_RS11980 glutathione (D-ribitylimino)-5,6-dihydrouracil glucose-6- subunit: accC isomerase: hydratase: dehydrogenase/ D-manno-heptose dTDP-4- E2 protein] N 6 lactoylglutathione dehydrogenase/ RS22895 phosphate a [carboxyl-carrier AzCIB_RS06320 2-oxoglutarate AzCIB_RS10100 methenyltetrahydrofolate CcmD RS08250 dehydrorhamnose enoyl-ACP a (2E)-oct-2-enoyl-[acp] -lipoyl-L-lysine lyase: gloA class III alcohol RS01125 6 dehydrogenase [+ 2 isozymes] (R)-S- cyclohydrolase FolD: folD isomerase: reductase: rfbD protein dimer]-N - dehydrogenase: reductase α-Kdo-(2->4)-α-Kdo-(2-> F6P 2-oxoglutarate E1 component: a 5-methylaminomethyl- an apo-[LYS2 L- (S)-5-amino-3- a hypoxanthine β-D-fructofuranose a [histone]-N 6 - UDP-N-acetyl- 4-bromo-2,3- AzCIB_RS06320 carboxybiotinyl-L-lysine (S)-3- lactoylglutathione a 5,10- + a [DNA]-3'- a siderophore- acyl-CoA/acyl-ACP geranyl 34 coenzyme A NAD(P)H a plastoquinone H acetyl-CoA an isocitrate selenide dTDP-β-L-rhamnose FabI: fabI 6)-(lauroyl)-lipid IV (E. coli) dehydrogenase AzCIB_RS09210 AzCIB_RS05045 selenophosphate 2-thiouridine 2-aminoadipyl- oxohexanoate in DNA 1-phosphate acetyl-L-lysine α-D-glucosamine dihydrodiol- a protein D-glucopyranose A hydroxyoctanoyl-CoA methenyltetrahydrofolate hydroxyl dehydrogenase bound Fe(III) dehydrogenase: E1 component: hydroxyacylglutathione diphosphate in tRNA carrier-protein] UDP-N- diphenyl ether selenide, 6-phosphate lipid A S-formylglutathione cis-2,3- bifunctional metalloprotease an octanoyl-[acp] AzCIB_RS12365 AzCIB_RS09210 hydrolase: gloB bifunctional acetylglucosamine water biosynthesis histone dihydrobiphenyl- isocitrate PmbA: pmbA [+ 3 isozymes] methylenetetrahydrofolate holo-ACP NAD(P)H:quinone 3-keto-5- exodeoxyribonuclease DNA-deoxyinosine fructose- 2-epimerase (non- dikinase RS17805 RS02980 RS16050 acyltransferase: β-D-fructose 1,6- [+ 3 isozymes]a [2-oxoglutarate a [2-oxoglutarate S-formylglutathione tRNA 2- 2,3-diol dehydrogenase metalloprotease beta-ketoacyl- (R)-lactate dehydrogenase/ oxidoreductase: wrbA aminohexanoate III: xth glycosylase: bisphosphate deacetylase: hydrolyzing): TrkA AzCIB_RS02310 cardiolipin biosynthesis I bisphosphate synthase: SelD: selD ACP synthase an octanoyl-[acp] dehydrogenase dehydrogenase 3-oxooctanoyl-CoA methenyltetrahydrofolate hydrolase: fghA selenouridine(34) cleavage protein: AzCIB_RS02725 aldolase class II: AzCIB_RS13995 dehydrogenase: kinase/ TldD: tldD 6 6 AzCIB_RS13790 NAD(P)H:quinone exodeoxyribonuclease AzCIB_RS18440 α-D-Kdo-(2->4)-α-D- E2 protein] N E2 protein] N -S- synthase α bphB phosphatase: selenophosphate II: fabF cyclohydrolase FolD: folD oxidoreductase: wrbA AzCIB_RS05345 III: xth AzCIB_RS04200 UDP-N-acetyl- - 4-bromo-2,3- a peptide Kdo-(2->6)-lipid A (E. coli) a CDP- fructose- -dihydrolipoyl- succinyldihydrolipoyl- acetyl-CoA C- formate MnmH: mnmH D-mannosamine dihydroxydiphenyl aceK Amino Acid Biosynthesis 10 a holo-[LYS2 L- a phosphorylated superpathway of L- diacylglycerol an N - an apurinic site Fe 2+ a siderophore L-histidine biosynthesis superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis II (acetyl cycle) superpathway of L-aspartate L-ornithine degradation a 3-oxodecanoyl-[acp] lipopolysaccharide bisphosphate L-lysine L-lysine acyltransferase: acetate a [histone]-L-lysine ether isoleucine biosynthesis I L-citrulline biosynthesis formyltetrahydrofolate 3',5'-ADP 2-aminoadipyl- (S)-3- a 2'- within DNA isocitrate porin and L-asparagine biosynthesis heptosyltransferase aldolase class II: AzCIB_RS20990 pyruvate a 5-methylaminomethyl- (2E)-3,7- + a [DNA]-3'- hypoxanthine D-glyceraldehyde RS18035 PilQ I (L-proline biosynthesis) carrier-protein] a plastoquinol NAD(P) acetoacetate deoxyribonucleoside DHAP dehydrogenase 1-(3-sn- formyltetrahydrofolate 34 aminobutanoyl-CoA hydroxyl RS17335 3-oxoacyl-ACP I: waaC AzCIB_RS04200 acetyl-CoA C- 2-selenouridine dimethylocta- oxaloacetate PRPP thr pyruvate N-acetylglutamyl- phosphatidyl) deformylase: purU 5'-monophosphate amino-acid N- gln glu reductase phosphatidylglycerol 2-oxoglutarate acyltransferase: in tRNA 2,6-diene-1-thiol aspartate/ phosphate L-ornithine heptosyl-Kdo -lipid A 5-hexynoate -sn-glycerol acetolactate acetyltransferase: FabG: fabG 2 biosynthesis I (plastidic) dehydrogenase AzCIB_RS12425 formyltetrahydrofolate tyrosine/aromatic ATP threonine ornithine biosynthesis 3-phosphate triose-phosphate synthase: AzCIB_RS04265 Asp-tRNA(Asn) [+ 2 isozymes] lipopolysaccharide E1 component: deformylase: purU A(H2) thiosulfate aminotransferase: phosphoribosyltransferase ammonia-lyase, cyclodeaminase: isomerase: a peptidoglycan dimer with lysine within a 3-(acyloxy) cis-3- a phosphorylated a [lipoyl-carrier /Glu-tRNA(Gln) DHAP phosphatidylglycerophosphatase hexanoyl-CoA + an L-arginyl- O-succinyl-L- chitin an L-aspartyl- AzCIB_RS13945 regulatory subunit: AzCIB_RS17595 N-acetyl- aspartate/ AzCIB_RS15840 heptosyltransferase hexanoate AzCIB_RS09210 pentapeptide stems (meso- an octanoyl-[acp] phylloquinone NAD(P)H H adenosylcobinamide acyl group of phenylcyclohexa- 6 squalene RS00580 BamB biosynthetic: ilvA bifunctional a (3R)-3- AzCIB_RS14885D-glyceraldehyde formate gcv protein H a protein Arg Asn isocitrate protein]-N -[(R) repressor LexA porin ilvN gamma-glutamyl- amidotransferase: tyrosine/aromatic II: waaF A: AzCIB_RS21275 DHAP [tRNA ] homoserine [tRNA ] squalene RS17285 AzCIB_RS03620 glutamate N- pro hydroxydecanoyl-[acp] bifunctional 3-phosphate 2-oxoglutarate acyl-CoA diaminopimelate containing) bifunctional bacterial toxin Asp-tRNA(Asn) 3,5-diene-1,2-diol dehydrogenase -dihydrolipoyl]- A tetrathionate aspartate/ threonine phosphate gatB gatA gatC an L-1- cis-2,3- bifunctional ATP acetolactate aminotransferase: acyl-ACP-- dehydrogenase: adenosylcobinamide L-lysine dihydrolipoyl transcriptional synthase A(H2) thiosulfate tyrosine/aromatic ammonia-lyase: acetyltransferase/ pro fumarate 3-hydroxyacyl- (heptosyl) -Kdo -lipid A sn-glycerol phosphatidyl- type I dehydrogenase beta-N- /Glu-tRNA(Gln) dihydrobiphenyl- isocitrate synthase: ilvN ilvB reductase: [+ 6 isozymes] AzCIB_RS13945 2 2 phospholipid O- lipoyl(octanoyl) NAD(P)H:quinone kinase/ repressor HpnC: TtrA aminotransferase: phosphoribosyltransferase: amino-acid ACP dehydratase complex AzCIB_RS22980 1,6-anhydro-N- O-succinylhomoserine acetylhexosaminidase: amidotransferase: 2,3-diol dehydrogenase dehydrogenase: AzCIB_RS21805 acetylglutamate AzCIB_RS04645 3-phosphate sn-glycerol glyceraldehyde- transferase oxidoreductase: wrbA arginyltransferase: LexA: lexA hpnC AzCIB_RS03830 AzCIB_RS03255 acetyltransferase aspartate/ acyltransferase/ dihydrolipoyllysine- [+ 24 isozymes] acetylmuramyl-L- sulfhydrylase: adenosylcobinamide- nagZ gatB gatA gatC dehydrogenase: kinase/ lpdA A tetrathionate (S)-2-acetolactate kinase: argB trifunctional glu FabZ: fabZ glycerol-3- cardiolipin 3-phosphate NAD(P)H:quinone AzCIB_RS09300 presqualene ArgJ: argJ tyrosine/aromatic aspartate long-chain-fatty- residue LipB: lipB AzCIB_RS15040 phosphate an L-asparaginyl- a [lipoyl-carrier cleaved porin asp 1-(5-phospho- (2Z)-2-aminobut-2-enoate gln N-acetyl-L-glutamate transcriptional synthase dehydrogenase: alanine amidase bphB phosphatase: [+ 2 isozymes] RS09465 glu N-acetyl-L-glutamate aminotransferase: ammonia- phosphate 1-O- acid--ACP ligase: (2E)-hexenoyl-CoA oxidoreductase: wrbA guanylyltransferase: [tRNA Asn ] protein]-N 6 -[(R repressor LexA diphosphate RsxA RS20615 β-D-ribosyl)-ATP ketol-acid 5-semialdehyde regulator/proline glutamate a (2E)-dec-2-enoyl-[acp] glucosyl-(heptosyl) succinyltransferase: AmpD: ampD N-acetyl-D- biphenyl-2,3-diol aceK acyltransferase ClsB: clsB gap a [glycine-cleavage chitin reductoisomerase: AzCIB_RS03830 lyase: aspA -Kdo -lipid A AzCIB_RS01010 odhB an N-terminal cobU a 3-hydroxyacyl an isocitrate )-lipoyl]-L-lysine aspartate kinase: phosphoribosyl- glutamine- N-acetylornithine dehydrogenase/L- 5-kinase: 2 2 PlsY: plsY enoyl-CoA acyl-carrier protein complex H protein] glucosamine ilvC enoyl-ACP Ptd Gro aldehyde Carboxylate Degradation γ a tRNA Arg succinate adenosyl-cobinamide group of a fatty acid dehydrogenase ATP hydrolyzing aminotransferase: glutamate gamma- AzCIB_RS16685 a 1-acyl-sn a hexanoyl-[acp] 2 hydratase: a peptidoglycan dimer with L-alanyl- -D-glutamyl- 6 + arginyl-[protein] L-homocysteine AzCIB_RS17725 bifunctional L-cysteine biosynthesis I dehydrogenase: N -octanoyl-L-lysine NAD(P) phylloquinol phosphate bacterial toxin diphosphatase: (2R)-2,3-dihydroxy- AzCIB_RS15570 semialdehyde reductase -glycerol 3- AzCIB_RS10100 pentapeptide stem (meso- meso-2,6-diaminopimeloyl- 2-iminobutanoate carbamoyl- glutamate N- γ-L-glutamyl asp AzCIB_RS03080 3-methylbutanoate dehydrogenase: FabI: fabI pyruvate fermentation diaminopimelate containing) D-alanyl-D-alanine L-aspartyl- AzCIB_RS03295 phosphate acetyltransferase/ L-isoleucine 5-phosphate glucosyl-(heptosyl) - phosphate [+ 2 isozymes] pyruvate decarboxylation to acetyl CoA I propanoyl CoA RS02030 2 2-oxoisovalerate decarboxylation to isobutanoyl-CoA to acetate IV superpathway of acetate BamE RS03240 4-phosphate 1-(5-phospho-β- dihydroxy-acid synthase: putA asparagine ser Kdo -lipid A-phosphate 1-acyl-sn-glycerol- 13-DPG RS17300 amino-acid biosynthesis IV a decanoyl-[acyl-carrier protein] 2 (S)-3- degradation I utilization and formation dehydratase: ilvD carB carA 3-phosphate a [pyruvate acrylate degradation II 4 D-ribosyl)-AMP acetyltransferase (S)-1-pyrroline- glutamate-5- synthase an [apo BCAA hydroxyhexanoyl-CoA an O - RNase III mRNA a [protein]- a [release factor]- a guanine 527 a [ribosomal a (2E,4E)-2,4- (3R)-3- aspartate- serine acetyltransferase: pyruvate dehydrogenase hydrogen selenide coenzyme A an apo-[aryl- a [protein]- FAD methyl red a ribonucleoside (E)-caffeoyl-CoA histidinol phosphoribosyl- dihydroxy-acid ArgJ: argJ propanoate 5-carboxylate (glutamine- beta-ketoacyl- acyltransferase: a 5-hexenoyl-[acp] acyl-CoA hydrolysis phosphoglycerate dehydrogenase pyruvate propanoyl-CoA acetate O-acetyl-L-serine methylthymine processing L-threonine protein L3]- hydroxyoctadecanoyl- semialdehyde semialdehyde 6 acetate- L-cysteine diphosphate L-glutamine in 16S rRNA dienoyl-CoA carbamoyl phosphate L-ornithine AzCIB_RS04090 AzCIB_RS19070 6 E2 protein] N pyruvate carrier protein] AMP 2-oxobutanoate dehydratase: ilvD propionate-- hydrolyzing): asnB ACP synthase kinase: pgk E2 protein] N alpha-ketoacid acyl-CoA coenzyme A acrylate in DNA substrate adenosylcobalamin- peptide chain 16S rRNA electron transfer L-glutamine50S ribosomal NADPH- CoA histidinol dehydrogenase: dehydrogenase: glucosyl-(heptosyl) - a 1,2-diacyl- -lipoyl-L-lysine -CoA acetoacetyl- N-acetyl-L-ornithine serine O- 3 a 2,3,4-saturated dehydrogenase dehydrogenase carboxylase acetate kinase: release factor (guanine(527)-N(7) flavoprotein cyclohydrolase: CoA ligase: AzCIB_RS16060 II: fabF -lipoyl-L-lysine ligase: dependent protein L3 dependent 2,4- CoA dehydrogenase: BamD asd acetolactate 3-methyl-2-oxobutanoate acetyltransferase: cysE Kdo -lipid A-phosphate sn-glycerol 3-phospho- (acetyl- AzCIB_RS11205 FAD:protein FMN FMN-dependent RS19700 AzCIB_RS16780 asn 2 fatty acyl CoA subunit beta: subunit beta: bifunctional O-acetylhomoserine holo-ACP methylated-DNA-- N(5)-glutamine )-methyltransferase subunit alpha: dienoyl-CoA hisD MerT RS20570 hisI 3-phosphate acyl-CoA D-glycerate dihydrolipoyl 3-oxohexanoyl-CoA acsA propionate-- ribonuclease III: transferase: ribonucleoside- N(5)-glutamine reductase: L-aspartate 4- β synthase: a 3-oxododecanoyl-[acp] AzCIB_RS09530 transferring), AzCIB_RS20440 acetate/ aminocarboxypropyltransferase/ synthase: [protein]-cysteine S- NADH- methyltransferase: RsmG: rsmG AzCIB_RS07265 reductase: 1-(5-phospho- -D-ribosyl)- [+ 8 isozymes] thioesterase: dehydrogenase: diphosphate an N 7 - methyltransferase: phbB semialdehyde AzCIB_RS17595 L-glutamate-5- asparaginase: O-acetyl-L-serine 2,3-bisphosphoglycerate- 2,3- acetyl-CoA formate homodimeric (S)-methylmalonyl- acetate- CoA ligase: AzCIB_RS13810 AzCIB_RS21835 azoreductase: 5-[(5-phosphoribosylamino) 2-isopropylmalate branched-chain propanoyl-CoA hydrogen sulfide a 5-hexynoyl-[acp] [+ 2 isozymes] acetyl-CoA propionate cysteine synthase: AzCIB_RS10725 AzCIB_RS13790 methyltransferase: reductase: prmC 527 [+ 5 isozymes] prmB AzCIB_RS09855 3-oxooctadecanoyl- his AzCIB_RS08770 AzCIB_RS11270 CoA AzCIB_RS16780 5 methylguanine a [ribosomal ilvN semialdehyde AzCIB_RS21080 3-oxoacyl-ACP independent diphosphoglycerate- acetyltransferase: type: aceE family kinase: -CoA AzCIB_RS16065 AzCIB_RS19905 a [release factor]-N a (2E)-2- CoA homoserine methylideneamino]imidazole- synthase: leuA amino acid ornithine glucosyl-(heptosyl) -Kdo bifunctional enoyl-CoA dihydrolipoyl [+ 2 isozymes] AzCIB_RS14795 in 16S rRNA hydrocaffeoyl-CoA 3 2 [+ 4 isozymes] phosphoglycerate dependent [+ 2 isozymes] ligase: acs a 2'- -methyl-L-glutamine protein L3]- enoyl-CoA dehydrogenase: 4-carboxamide acetolactate 2-isopropylmalate transaminase: 2-oxoacid:ferredoxin arg type II reductase a CDP- a 2,3,4-saturated AzCIB_RS12405 [+ 2 isozymes] AzCIB_RS20785 RNase III a [protein]-FMN- carbamoyltransferase: bifunctional O-acetylhomoserine -lipid A-bisphosphate an [apo BCAA hydratase/phosphate dehydrogenase: 3',5'-ADP a holo-[aryl- deoxyribonucleoside N 5 -methyl- synthase: ilvN ilvB oxidoreductase ornithine- asparaginase: FabG: fabG fatty acid mutase: phosphoglycerate an [apo BCAA dehydrogenase acetyl phosphate acetyl-CoA acryloyl-CoA an mRNA fragment processing L-threonine N,N-dimethyl-1,4- RS02550 AzCIB_RS14390 1-(5-phosphoribosyl)-5- synthase: AzCIB_RS04495 argF aminocarboxypropyltransferase/ diacylglycerol dehydrogenase [+ 3 isozymes] acetyltransferase: AzCIB_RS11270 a [pyruvate carrier protein] a [protein]-S- AMP BamA subunit beta: AzCIB_RS16975 AzCIB_RS22880 mutase: gpmA 6 acetate a thymine in DNA anthranilate 5'-diphosphate L-glutamine RS03945 RS16970 (S)-2-aceto-2- -oxo-acid [+ 2 isozymes] 6 E2 protein] N -S-[2- a [pyruvate L-selenocysteine methyl-L-cysteine product mRNA phenylenediamine [(5- phosphoribosylamino) AzCIB_RS17670 cysteine synthase: AzCIB_RS10725 E2 protein] N AzCIB_RS20780 [+ 2 isozymes] dehydrogenase (R)-methylmalonyl- L-homoserine hydroxybutanoate superpathway AzCIB_RS22325 transaminase: arginase: methylpropanoyl]dihydrolipoyl- butanoyl-CoA dehydrogenase methylideneamino]imidazole-4- [+ 2 isozymes] a (3R)-3- 2-phospho- -dihydrolipoyl- E2 protein] N 6 -S- CoA val of L-threonine rocD rocF asp galactosyl-glucosyl- L-lysine phosphate E2 protein] N 6 - carboxamide isomerase: hisA ketol-acid [+ 2 isozymes] hydroxydodecanoyl-[acp] D-glycerate L-lysine acyl-CoA dihydrolipoyllysine- acetyldihydrolipoyl- methylmalonyl- homoserine (2S)-2-isopropylmalate biosynthesis (heptosyl) -Kdo - 1-(3-sn- acetyltransferase: pta dihydrolipoyl-L-lysine reductoisomerase: 3 2 2503 all-trans- 966 38- (3R)-3- phosphoribulosylformimino- 2-oxobutanoate phosphatidyl) phosphopyruvate dehydrogenase: residue L-lysine CoA mutase: bifunctional enoyl- adenine an [HPr]- phosphoenol a uridine 34 a thiocarboxylated an sn-glycero-3- an [RNA]-3'- a guanine a uridine hydrogen a (2E,4Z)-2,4- kinase: 3-hydroxyacyl- lipid A-bisphosphate 3-hydroxypropanoyl- pimeloyl-CoA fumarate A(H2) a DNA segment 2+ 2+ ilvC 3-isopropylmalate oxaloacetate cys hydratase: AzCIB_RS22980 acetyltransferase: AzCIB_RS08820 propanoyl-CoA [SAMP] C- phospho-N-(acyl) hexaprenyl ala asp ribonucleoside- hydroxypentanoyl- Zn RS05745 Zn AzCIB_RS02405 AICAR-phosphate L-ornithine ACP dehydratase -sn-glycerol acetyl phosphate CoA hydratase/ CoA in 23S rRNA L-histidine pyruvate in tRNA 4-aminobenzoate in 16S rRNA 40 in tRNA peroxide dienoyl-CoA (R)-2,3-dihydroxy- dehydratase: L-citrulline aspartate/ acetolactate AzCIB_RS09755 aceF terminal glycine ethanolamine diphosphate 2',3'- 16S rRNA RluA family NADPH- CoA RS23485 FabZ: fabZ 3-phosphate 2-oxo acid [+ 24 isozymes] methylmalonyl- phosphate acetoacetyl- O-phospho- 3-methylpentanoate leuD leuC tyrosine/aromatic synthase: acetate kinase: cyclophosphate (guanine(966)-N(2) pseudouridine dependent 2,4- recombinase imidazole ornithine phosphatidylglycerophosphatase phosphoenol dehydrogenase CoA acetyltransferase: 23S rRNA phosphoenolpyruvate- RNA 2',3'-cyclic catalase/ CoA L-homoserine L-lysine biosynthesis I argininosuccinate aminotransferase: AzCIB_RS17595 galactosyl-(glucosyl) crotonyl-CoA AzCIB_RS11205 tRNA 2- L-aspartate )-methyltransferase synthase: dienoyl-CoA RecA: recA glycerol dihydroxy-acid carbamoyltransferase: a (2E)-dodec-2-enoyl-[acp] A: AzCIB_RS21275 pyruvate subunit E2: mutase: scpA AzCIB_RS20780 -protein 4-hydroxybenzoate 8-amino-7- phosphodiesterase: peroxidase reductase: 2-isopropylmaleate synthase: AzCIB_RS13945 -(heptosyl) -Kdo - (adenine(2503)-C(2) glycerophosphodiester oxidase: threonine dehydratase: ilvD ilvN 2 3 2 acetate/propionate family thiouridine(34) octaprenyltransferase: oxononanoate 2 RsmD: rsmD AzCIB_RS13925 reductase: a DNA segment LptC phosphate argF an L-1- pyruvate AzCIB_RS09535 enoyl-CoA phosphate cyclohexane-1-carboxylate )-methyltransferase phosphotransferase: ptsP phosphodiesterase: ugpQ thpR an N - HPI: katG phbB AzCIB_RS15560 aspartate/ enoyl-ACP lipid A-bisphosphate succinyl-CoA synthase nadB an [RNA]-3'- AzCIB_RS09855 3-oxopentanoyl- in reverse synthase: synthase: dihydroxy-acid 3-isopropylmalate asp acetolactate phosphatidyl- kinase: pyk kinase: AzCIB_RS20785 acetyl-CoA glycolate and AzCIB_RS20905 synthase: bioF methylguanine 966 [+ 3 isozymes] 2-oxo acid hydratase: acetyltransferase: pta degradation (anaerobic) RlmN: rlmN a pseudouridine 38- a (2E)-2- AzCIB_RS14385 tyrosine/aromatic reductase MnmA: mnmA ribunucleoside- CoA orientation YidC hisH hisF dehydratase: ilvD dehydratase: synthase: ilvN ilvB L-citrulline sn-glycerol pyruvate AzCIB_RS10100 glyoxylate an [HPr protein]- in 16S rRNA aspartate kinase: L-arginino-succinate aminotransferase: L-methionine biosynthesis III FabI: fabI dehydrogenase acetate 2'-phosphate 40 in tRNA enoyl-CoA (3S)-3-methyl-2- leuD leuC (S)-2-aceto-2- degradation II cyclohexane- π pyruvate an N- 3-all trans- 2-iminosuccinate succinate A H O kinase: pyk subunit E2: [+ 2 isozymes] 2503 N -phospho- sn-glycerol (8S)-8-amino-7- 2 thr AzCIB_RS17725 AzCIB_RS03830 a 2-methyladenine 34 coenzyme A D-erythro-1- oxopentanoate hydroxybutanoate galactosyl-(glucosyl) fatty acid elongation -- saturated 1-carboxylate 5'-deoxyadenosine a [SAMP] C- a 2-thiouridine acylethanolamine hexaprenyl-4- argininosuccinate a dodecanoyl-[acp] AzCIB_RS05080 (S)-3- glycolate cyclohexanecarboxylate- met L-histidine 3-phosphate oxononanoate AICAR (imidazol-4- (2R,3S)-3-isopropylmalate L-aspartyl-4-phosphate asp -(heptosyl) -Kdo - pyruvate in 23S rRNA terminal glycine in tRNA aminobenzoate branched-chain lyase: argH L-homoserine 3 3 2 glycolate CoA ligase: aliA GspG threonine hydroxybutanoyl-CoA yl)-glycerol amino acid lipid A-bisphosphate oxidase: ammonia- 3-isopropylmalate an acetoacetyl-[acp] cyclohexanecarboxylate- 3-phosphate transaminase: aspartate- arg aspartate kinase: homoserine O- glcF glcE lyase, dehydrogenase: (R)-2,3-dihydroxy- L-tryptophan biosynthesis beta-ketoacyl- CoA ligase: aliA β RS01105 imidazoleglycerol- cyclohexane-1- N-acetyl- -D-glucosamine- 2030 46 phosphoenol AzCIB_RS04495 leuB semialdehyde AzCIB_RS17725 acetyltransferase: ACP synthase glyoxylate an N-terminal an L-phenylalanyl- a proteinogenic a [protein]- a DNA methyl an (S)-2- a ribonucleoside adenine a guanine (2R,3S)-2- a [protein]- biosynthetic: phosphate 3-methylpentanoate carbonyl-CoA leukotriene-C4 1,6-anhydro-N- a single canavaninosuccinate L-threonine 3- dehydrogenase: AzCIB_RS23160 core oligosaccharide- arginyl-[protein] Phe L-cysteine phosphotriester halocarboxylate in 23S rRNA in tRNA GTP methylisocitrate L-histidine pyruvate (2S)-2-isopropyl- II: fabF TCA cycle TCA cycle I (prokaryotic) acetoacetyl-CoA [tRNA ] amino acid triphosphate stranded DNA O-phosphate ilvA dehydratase asd L-aspartyl- dihydroxy-acid malate cyclohexanecarboxyl- acetyl-β-D-muramate 23S rRNA tRNA bifunctional pyruvate ile chorismate gln laurate lipid A (E. coli K-12 histidine kinase: HisB: hisB 3-oxosuccinate dehydratase: ilvD O-acetyl-L- synthase G: CoA (adenine(2030)-N(6) (guanosine(46)-N7) adenylate/guanylate aconitate threonine- kinase: pyk RS23700 threonine L-aspartate 4- 4-phosphate hydrogen sulfide core type) (no GlcNAc) AzCIB_RS07845 3-(imidazol-4- homoserine acetyl-CoA acetyl-CoA C- dehydrogenase: aliB methylated-DNA-- HAD family argininosuccinate )-methyltransferase -methyltransferase cyclase domain- phosphate ammonia-lyase: dihydroxy-acid a 3-oxotetradecanoyl-[acp] acyl-CoA AzCIB_RS16290 leucyl/phenylalanyl- beta-N- DNA primase: hydratase 2/2- [+ 5 isozymes] pyruvate yl)-2-oxopropyl semialdehyde L-arginine aspartate- a 3-oxoacyl-[acp] acyltransferase: gamma- [protein]-cysteine S- hydrolase: decarboxylase: AzCIB_RS21805 anthranilate synthetase: cyclohex-1-ene- tRNA--protein acetylhexosaminidase: lyase: argH 6 RlmJ: rlmJ 7 TrmB: trmB containing protein: methylisocitrate a [protein]- kinase: pyk CcmD degradation I dehydratase: ilvD AzCIB_RS12425 (S)-malate methyltransferase: AzCIB_RS16110 an N - an N - phosphate 4-hydroxy- semialdehyde synthase component AzCIB_RS21235 oxaloacetate transferase: glutamyltransferase: ggt AzCIB_RS17530 AzCIB_RS09265 (R)-1-amino-AzCIB_RS20620 N-phospho- (2Z)-2-aminobut- (3S)-3-methyl-2- bifunctional O-acetylhomoserine 3-oxoacyl-ACP 1-carbonyl-CoA nagZ 2030 methylguanine 46 dehydratase: pyruvate histidinol- (arginase pathway) [+ 3 isozymes] AzCIB_RS16065 [+ 2 isozymes] methyladenine 2-propanol O 4-methyl-2-oxopentanoate tetrahydrodipicolinate dehydrogenase: I: AzCIB_RS18715 aminocarboxypropyltransferase/ reductase [+ 7 isozymes] core oligosaccharide-lipid beta- AzCIB_RS09295 cyclic-GMP AzCIB_RS14480 L-histidine 2-enoate oxopentanoate in 23S rRNA in tRNA -2-phosphate phosphate synthase: asd cysteine synthase: AzCIB_RS10725 UDP A (E. coli K-12 core type) ketoacyl- cis-2- arg branched-chain FabG: fabG citrate (Si)-synthase: gltA acetyl-CoA an α-(γ-L-glutamyl) ssDNA/pppN(pN) L-canavanine fumarate RS00915 transaminase: branched-chain AzCIB_RS17870 lauroyl-CoA leukotriene-D4 1,6-anhydro-N- methylaconitate L-aspartate 4- O-acetylhomoserine [+ 2 isozymes] ACP L-phenylalanyl-L- -L-amino acid a [protein]-S- GlcNAc an (S)-2- hybrid amino acid (2S,4S)-4- arginase: amino acid anthranilate PRPP Phe [DNA] acetyl-β-muramate a halide anion n -1 AzCIB_RS03265 semialdehyde beta- reductase: arginyl-[protein] a tRNA methyl-L-cysteine hydroxycarboxylate transaminase: hydroxy-2,3,4,5- rocF transaminase: aminocarboxypropyltransferase: FlhA L-histidinol a (3R)-3- ketoacyl- phbB Aromatic Compound Degradation 2-iminobutanoate AzCIB_RS04495 tetrahydrodipicolinate homoserine AzCIB_RS04495 AzCIB_RS14750 malate dehydrogenase: phosphate superpathway of L-serine L-ornithine anthranilate hydroxytetradecanoyl-[acp] ACP dehydrogenase: [+ 2 isozymes] and glycine biosynthesis I 4-hydroxy- stearate biosynthesis phosphatidylglycerol synthase AzCIB_RS09250 3-phenylpropanoate and 3-(3- phosphoribosyltransferase: trpD 3-hydroxyacyl- all-trans- an N-acetyl-β- a (1->4)- 37 leu tetrahydrodipicolinate ornithine- AzCIB_RS14390 ile II (bacteria and plants) a (3R)-3- phenylacetate benzoyl-CoA protocatechuate an N-terminal an L-phenylalanyl- a proteinogenic an (R)-2- a guanine RS17305 L-homocysteine ACP dehydratase biosynthesis II (non-plastidic) a 2,3,4-saturatedII: fabF hydroxyphenyl)propanoate degradation glutathione isobutanoate nonaprenyl D-hexosaminide α 3-O-methylgallate a phenyl acetate DNA with lesion CAIR hydroxyacyl-[acyl- Phe halocarboxylate -D-glucan in tRNA a protein 3-phospho-D-glycerate reductase: dapB -oxo-acid fatty acyl-[acp] degradation I (aerobic) degradation II (anaerobic) degradation I (meta L-lysyl-[protein] [tRNA ] amino acid 4-hydroxybenzoate ATP L-homoserine FabZ: fabZ (S)-malate citrate diphosphate aromatic tRNA excinuclease 5-(carboxyamino) (S)-2,3,4,5- transaminase: N-(5-phosphoribosyl)-anthranilate 3-hydroxyacyl-carrier protein] -cleavage pathway) 2-oxobutanoate methionine methionine a palmitoyl-[acp] DHAP 3-phenylpropanoate ring-opening (guanosine(37)-N1) adenylate/guanylate ABC subunit imidazole RS08040 histidinol tetrahydrodipicolinate rocD ACP bifunctional aconitate coenzyme A phenylacetate benzoyl-CoA beta-N- endopeptidase La: homoserine synthase: synthase: a (2E)-tetradec-2-enoyl-[acp] beta-ketoacyl- protocatechuate leucyl/phenylalanyl- acetate--CoA ligase: acsA HAD family alpha-glucosidase: dioxygenase LigA: -methyltransferase cyclase domain- arylesterase: UvrC: uvrC ribonucleotide phosphoribosylanthranilate dehydratase hydratase 2/2- 3-phenylpropionate/ benzoyl- 4-hydroxybenzoate acetylhexosaminidase: AzCIB_RS14330 acetolactate 3-phosphooxypyruvate 2,3,4,5- L-glutamate-5- metH metH ACP synthase aromatic gamma- hydrolase: AzCIB_RS21060 histidinol kinase: isomerase: AzCIB_RS15080 tRNA--protein acetate--CoA ligase: acs octaprenyltransferase: AzCIB_RS12110 1 TrmD: trmD containing protein: AzCIB_RS13125 [+ 2 isozymes] mutase: purE L-proline L-phenylalanine enoyl-ACP FabZ: fabZ methylisocitrate cinnamic acid CoA nagZ 4-carboxy-2-hydroxy- an N - synthase: dehydrogenase: tetrahydropyridine- semialdehyde AzCIB_RS02405 II: fabF sn-glycerol phenylacetate-- ring-opening transferase: glutamyltransferase: ggt AzCIB_RS17530 AzCIB_RS09265 DNA without biosynthesis I a 3-oxooctadecanoyl- dehydratase: dioxygenase reductase, benzoyl-CoA degradation III (anaerobic) AzCIB_RS20905 6-methoxy-6- methylguanine 37 a peptide AIR RS17380 AzCIB_RS17595 3-phosphoserine/ biosynthesis I 2,6-dicarboxylate N- 1-(2-carboxyphenylamino)-1- met reductase 3-phosphate CoA ligase: paaF dioxygenase LigA: [+ 2 isozymes] cyclic-AMP lesion hisD O-phospho- [acp] fumarate hydratase: bzd-type: AzCIB_RS09295 β a (1->4)- oxohexa-2,4-dienoate phosphohydroxythreonine (from L-glutamate) trifunctional deoxy-D-ribulose 5-phosphate FabI: fabI AzCIB_RS14480 subunit beta: an N-acetyl- - D-glucopyranose in tRNA ilvN succinyltransferase: glycerol-3- AzCIB_RS06610 phenylacetate-- AzCIB_RS12110 an alcohol α-D-glucan acetate RS21090 transcriptional L-homoserine chorismate 3-oxoacyl- AzCIB_RS12060 bzdN benzoyl-CoA an α-(γ-L-glutamyl) isobutanoyl-CoA diphosphate D-hexosamine a phenol histidinal transaminase: serC dapD indole-3-glycerol phosphate 1-O- aconitate hydratase CoA ligase: paaF HCMS L-cysteinylglycine AMP 3-nonaprenyl-4- acetolactate glu regulator/proline chorismate class II fumarate bzdO bzdQ L-phenylalanyl- -L-amino acid a (2R)-2- threonine phosphate a myristoyl-[acp] ACP AcnA: acnA 3-(5,6- benzoyl-CoA Phe hydroxybenzoate a halide anion synthase: N-succinyl-2-amino- acyltransferase acyl-CoA/acyl-ACP a trans-2- hydratase: fumC L-lysyl-[protein] a tRNA hydroxy fatty acid histidinol O-phospho-L-serine glutamate dehydrogenase/L- synthase: mutase: pheA synthase TrpC: trpC reductase a 2,3,4-saturated dihydroxycyclohexa- reductase, bzd- ilvN ilvB 6-ketopimelate PlsY: plsY dehydrogenase: enoyl-[acyl- benzoyl- dehydrogenase: 5-kinase: glutamate gamma- prephenate beta-ketoacyl- FabG: fabG fatty acyl-[acp] fumarate cis-aconitate 1,3-dien-1-yl) phenylacetyl-CoA type: bzdN AzCIB_RS14385 a 1-acyl-sn AzCIB_RS07610 carrier protein] CoA YidD (S)-2-aceto-2- hisD succinyldiaminopimelate semialdehyde (1S,2R)-1-C-(indol-3- ACP synthase bifunctional phosphoserine γ-L-glutamylAzCIB_RS16685 [+ 2 isozymes] -glycerol 3- bifunctional aconitate propanoate reductase, bzdO bzdQ 2-hydroxy-4- yl)glycerol 3-phosphate [+ 3 isozymes] succinate dehydrogenase/ decaprenyl-diphospho-N- 37 hydroxybutanoate phosphatase/homoserine transaminase: dehydrogenase: thr prephenate ammonia assimilation cycle III II: fabF a (3R)-3- hydratase 2/2- 3-(3- phenylacetate- UDP-N-acetyl- a Chi-site containing a RecA DNA all-trans- α-D-glucopyranose a 3,5,7,9,11,13,15- guanine (S)-3- RS18365 5-phosphate phosphate bzd-type: benzoyl-CoA carboxymuconate glutathione ferulate sulfite GSSH an L-glutamyl- [DNA] 1-propanal Fe 2+ his AzCIB_RS13650 dehydratase: fumarate reductase CoA oxygenase/ α-D-glucosamine acetylmuramoyl-pentapeptide hypoglycin A double stranded recombination heptaprenyl hepta-oxo- Phe aminobutanoyl- ketol-acid phosphotransferase putA tryptophan synthase: hydroxyoctadecanoyl- methylisocitrate 2,3-dihydroxy-2,3- hydroxyphenyl) 4-hydroxybenzoate CTP 1-phosphate in tRNA [tRNA Gln ] glutamate-5- a 3-oxohexadecanoyl-[acp] 1-acyl-sn-glycerol- iron-sulfur subunit: reductase: paaA bzdQ reductase, bzd- semialdehyde and repair protein diphosphate DNA CoA aldehyde reductoisomerase: ThrH: thrH N-succinyl-L,L-2,6- pheA AzCIB_RS15070 trpB [acp] enoyl-ACP dehydratase: dihydrophenylpropionate propanoate DNA with a blunt end hexadecanoyl-[PKS-acp] tRNA Asp-tRNA(Asn) 3-aminobutyryl- bacterioferritin: ammonium 3-phosphate AzCIB_RS02205 cyclohex-bzdO bzdN type: bzdQ hemiacetal aldo/keto ilvC semialdehyde diaminopimelate glu 3-phenyl-2- 3-hydroxyacyl- reductase dehydrogenase: AzCIB_RS01670 undecaprenyldiphospho- (guanosine(37)-N1) /Glu-tRNA(Gln) polymerase ferredoxin AzCIB_RS19650 phosphoserine acyltransferase: 9-decynoate AzCIB_RS14480 bzdO bzdN glucose-1-phosphate CoA ammonia- dehydrogenase: ser glutamate glu 3-oxoacyl-ACP succinate dehydrogenase paaC paaJ paaK 1,5-diene-1- muramoylpentapeptide beta-N- feruloyl-CoA synthase: rhodanese: reductase: -methyltransferase III subunit oxidoreductase: CcmB (R)-2,3-dihydroxy- phosphatase SerB: serB succinyl- oxopropanoate alanine indole ACP biosynthesis FabI: fabI aconitate hydratase AzCIB_RS12075 cyclohex-1,5-diene- exodeoxyribonuclease 4-hydroxybenzoate cytidylyltransferase: amidotransferase: lyase: [+ 2 isozymes] AzCIB_RS16060 synthase reductase AzCIB_RS19070 2-(1,2-epoxy-1,2- carbonyl-CoA gamma- AzCIB_RS13515 AzCIB_RS21785 AzCIB_RS05170 TrmD: trmD epsilon: dnaQ AzCIB_RS14280 3-methylpentanoate diaminopimelate aspartate/ racemization dehydratase a 1,2-diacyl- flavoprotein subunit: 1-carbonyl-CoA acetylglucosaminyltransferase: octaprenyltransferase: 9-hydroxy-3,5,7,11,13,15- an N 1 - gatB gatA gatC AzCIB_RS05340 L-alanine subunit type I AcnA: acnA cyclohexa-1,5- glutamyltransferase: ggt V: recC recB recD rfbF Fe 3+ RS03710 ser FabG: fabG FabZ: fabZ AzCIB_RS09230 dihydrophenyl) 2-pyrone-4,6- murG AzCIB_RS20905 37 an L-glutaminyl- [+ 3 isozymes] propanoate dihydroxy-acid superpathway of L- L-glutamate-5- desuccinylase: biosynthesis III tyrosine/aromatic 2-oxoglutarate glutamate- sn-glycerol decanoate hexaoxohexadecanoyl- methylguanine a 2'- crotonyl-CoA tryptophan synthase: beta: gltD 2,3-DHP acetyl-CoA dienecarbonyl- [tRNA Gln ] semialdehyde [+ 2 isozymes] 3-phosphate succinate D-threo-isocitrate dicarboxylate in tRNA Phe dehydratase: asparagine biosynthesis dapE aminotransferase: ala -ammonia a (2E)-octadec- bifunctional CoA hydratase: [PKS-acp] deoxyribonucleoside serine AzCIB_RS15070 trpB NADP-specific NADP-dependent 2-(1,2-epoxy-1,2- a double stranded DNA feruloyl-CoA glutathione thiosulfate CDP-α-D-glucose AzCIB_RS03830 alanine ligase: glnA a (3R)-3- 2-enoyl-[acp] acyl-ACP-- decaprenyl-pyrophosphoryl- UDP diphosphate 5'-monophosphate ilvD cys glutamate isocitrate dehydrogenase: dihydrophenyl) AzCIB_RS22340 cyclohex-1-ene- hypoglycin B L-cysteinylglycine 3-heptaprenyl-4- AMP hydroxymethyltransferase: L,L-diaminopimelate hydroxyhexadecanoyl-[acp] phospholipid O- fatty acid biosynthesis (N-acetylglucosamine)-N- with a RecA protein FlhF dihydroxy-acid asp L-glutamate SufS family aspartate/ racemase: enoyl-ACP AzCIB_RS16340 6-hydroxycyclohex- 1-carbonyl-CoA hydroxybenzoate AzCIB_RS10535 dehydrogenase: initiation (type II) ADP-forming succinate- acetyl-CoA acetylmuramyl-(pentapeptide) loaded 3' overhang biosynthesis III tyrosine/aromatic alr trp acyltransferase/ (2Z,4E)-2- 1-ene-1- (1E)-4-oxobut- dehydratase: cysteine AzCIB_RS20390 3-hydroxyacyl- reductase a CDP- -CoA ligase: sucC sucD NADP-dependent isomerase: [+ 2 isozymes] (S)-1-pyrroline- diaminopimelate aminotransferase: D-ala long-chain-fatty- Pentose Phosphate Pathways carbonyl-CoA 1-ene-1,2,4- RS18530 ilvD desulfurase: ACP dehydratase FabI: fabI diacylglycerol acetyl-CoA isocitrate dehydrogenase: hydroxy-6- AzCIB_RS01645 asparagine asparagine 5-carboxylate epimerase: dapF 2-oxoglutarate AzCIB_RS13945 Asp-tRNA(Asn) acid--ACP ligase: 6-hydroxycyclohex- tricarboxylate gly sufS FabZ: fabZ oxonona-2,4- 10 all-trans- trimethylamine adenine 1518 / an N-terminal L- a cytidine 34 6-oxocyclohex- an adenine 34 (3S)-3-methyl-2- ammonium /Glu-tRNA(Gln) gln AzCIB_RS01010 acetyl-CoA AzCIB_RS16335 2-oxepin-2(3H)- a [2-oxoglutarate-dehydrogenase a sulfurated an L-methionyl- an N - a reduced c- a holo [PedN acyl- roseoflavin synthase synthase pyrroline-5- glutamate synthase a stearoyl-[acp] 1-ene-1- 2-hydroxy-cyclohexane- hydrogen cyanide 1519 alanyl-[S18 protein biphenyl-2,3-diol 7,8-dihydropterin oxopentanoate [+ 3 isozymes] pentose phosphate pathway diene-1,9-dioate a sulfurated [sulfur carrier] SAM Met decaprenyl N-oxide adenine in 16S rRNA in tRNA 1-ene-1- in tRNA a decanoyl-[acyl- carboxylase ylideneacetyl-CoA E2 protein] N 6 -octanoyl-L-lysine [sulfur carrier] [initiator tRNA ] formyltetrahydrofolate 4-hydroxybenzoate type cytochrome carrier protein] (glutamine- (glutamine- carboxylate meso-diaminopimelate subunit beta: gltD ala phe amidotransferase: a (2E)-hexadec-2-enoyl-[acp] carbonyl-CoA 1-carbonyl-CoA diphosphate 16S rRNA of 30S ribosome] 2,3- tRNA (cytidine(34) carbonyl-CoA bifunctional tRNA RS17990 branched-chain carrier protein] carboxyltransferase ribosomal protein 6-oxocyclohex- guanine hydrolyzing) hydrolyzing) reductase: NADP-specific gatB gatA gatC 1-(3-sn- D-glucopyranose dehydrogenase: (adenine(1518)-N(6)/ ACP S- dihydroxybiphenyl -2'-O)- riboflavin kinase/ adenosine(34) amino acid subunit beta: 2-hydroxycyclohexanecarboxyl- (1E,3E)-4- S18-alanine N- 1-ene-1- deaminase: : asnB : asnB AzCIB_RS19460 glutamate [+ 6 isozymes] enoyl-ACP phosphatidyl) succinyl-CoA 2-oxoglutarate 6-phosphate had adenine(1519)-N(6))- malonyltransferase: 1,2-dioxygenase: methyltransferase: FAD synthetase: deaminase XrtB transaminase: diaminopimelate AzCIB_RS15065 (2Z)-2- CoA dehydrogenase: badH hydroxybuta- rhodanese: 4-hydroxybenzoate acetyltransferase: carbonyl-CoA guaD reductase -sn-glycerol lipoyl synthase: lipA fabD AzCIB_RS04330 AzCIB_RS16500 decarboxylase: lysA dehydrogenase: malonyl-CoA glucose-6- 3-oxo-5,6- 6-hydroxycyclohex- 1,3-diene-1,2,4- AzCIB_RS21785 octaprenyltransferase: dimethyltransferase an N-terminal N-acetyl-rimI a malonyl[PedN 2-hydroxy-6-oxo-AzCIB_RS23945 a 2'-O- TadA: tadA 7,8- AzCIB_RS04495 pro FabI: fabI 3-phosphate hydroxypenta- 2-ketocyclohexane- [+ 2 isozymes] hydratase: oah roseoflavin a hypoxanthine AzCIB_RS20390 stearate phosphate didehydrosuberyl- 1-ene-1- tricarboxylate AzCIB_RS20905 6 RsmA: rsmA1518 34 a dec-9- 2,4-dienoate 1-carbonyl-CoA N -dimethyladenine L-alanyl-[S18 protein acyl-carrier 6-phenylhexa- methylcytidine [+ 2 isozymes] 34 dihydrolumazine asn asn phosphatidylglycerophosphatase ACP S- CoA semialdehyde 5'-phosphate in tRNAs ile lys glu glu enoyl-[acyl- dehydrogenase: 2-keto-4- carbonyl-CoA /N 6 -dimethyladenine 1519 of 30S ribosome] protein] 2,4-dienoate in tRNA 3-hydroxypimeloyl- RS18060 a palmitoyl-[acp] long-chain-fatty- A: AzCIB_RS21275 an unsulfurated carrier protein] malonyltransferase: zwf dehydrogenase: 2-ketocyclohexanecarboxyl- a [2-oxoglutarate dehydrogenase thiocyanate an N-formyl- in 16S rRNA CoA acid--CoA ligase: an L-1- pentenoate 5'-deoxyadenosine a tetrahydrofolate 3-decaprenyl-4- an oxidized c- trimethylamine fabD 2-oxoglutarate 6-phospho had CoA hydrolase: badI met 6 an unsulfurated [sulfur carrier] [sulfur carrier] L-methionyl- hydratase: 2-hydroxy-4- E2 protein] N -lipoyl-L-lysine hydroxybenzoate RS13985 AzCIB_RS15145 phosphatidyl- 6-oxocyclohex- met type cytochrome dehydrogenase D-glucono- AzCIB_RS07485 3-oxo-5,6- oxobutane-1,2,4- [initiator tRNA ] [+ 7 isozymes] sn-glycerol a malonyl-[acp] 1-ene-1- pimeloyl-CoA E1 component: 1,5-lactone didehydrosuberyl- tricarboxylate a dec-9- 2-oxopent- carbonyl-CoA stearoyl-CoA AzCIB_RS09210 6-phosphogluconolactonase: CoA UDP-α-D- palmitate ynoyl-[acyl- 4-enoate 6-oxocyclohex- a [glycine-cleavage complex H a 1,2-diacyl- an N-terminal all-trans- 3-benzyl-3,6 -bis(cysteinyl) a cytidine 2498 an insertion sequence a uracil 1498 a [protein]-L- an adenosine 34 TolQ Nucleoside and Nucleotide Biosynthesis ketoacyl-ACP an L-arginyl- maltotriose a holo [PedD acyl- glutaraldehyde MeOH carrier protein] pgl 3-oxo-5,6- a sulfurated [sulfur carrier] SAM 6 galactose 3-sulfo-L- hexaprenyl - 6-(hydroxymethyl) ω Arg2 hydratase: 1-ene-1- protein] N -octanoyl-L-lysine sn-glycerol [tRNA Arg ] 4-hydroxybenzoate in 23S rRNA element IS30 in 16S rRNA proline ( = 180) in [tRNA ] long-chain-fatty- synthase III: fabH dehydrosuberyl- carrier protein] peptidylprolyl D-gluconate dmpE carbonyl-CoA alanyl-[protein] diphosphate -diketopiperazine 23S rRNA transposase: 16S rRNA aldehyde tRNA catalase/ ACP S- isomerase: RS18845 superpathway of pyrimidine acid--CoA ligase: 6-phosphate CoA 2,3-didehydropimeloyl-CoA oxaloacetate (cytidine(2498)-2'-O) AzCIB_RS24105 (uracil(1498)-N(3))- ferredoxin adenosine(34) peroxidase superpathway of guanosine superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis I 5-aminoimidazole ribonucleotide biosynthesis I an acetoacetyl-[acp] (S)-4-hydroxy- hydratase: oah alpha-glucosidase: malonyltransferase: ribonucleotides de novo biosynthesis guanine and guanine and AzCIB_RS15145 thiolase: pcaF galactosyldiacylglycerol 4-hydroxybenzoate -methyltransferase [+ 9 isozymes] methyltransferase: AzCIB_RS10070 oxidoreductase: deaminase HPI: katG nucleotides de novo biosynthesis I adenosine nucleotides guanosine salvage guanosine salvage II 2-oxopentanoate [+ 2 isozymes] lipoyl synthase: lipA arginyltransferase: putative C-S lyase: AzCIB_RS21060 fabD [+ 7 isozymes] trans-2,3- 2-hydroxy-6- synthase: AzCIB_RS06095 octaprenyltransferase: RlmM: rlmM an insertion 3 AzCIB_RS04255 [+ 10 isozymes] AzCIB_RS14280 TadA: tadA de novo biosynthesis I UDP CTP 4-hydroxy-2- [+ 2 isozymes] AzCIB_RS09300 AzCIB_RS19955 a 2-O- a malonyl- an N - a [protein]-L- glutarate an inosine 34 formaldehyde PRPP dehydroadipyl-coA 2498 sequence IS30 with 1498 MurJ gln oxocyclohexane- AzCIB_RS20905 [PedD acyl- methyluracil Arg2 hydrogencarbonate adenosylcobalamin- palmitoyl-CoA D-ribulose oxovalerate methylcytidine proline (ω = 0) semialdehyde in [tRNA ] IMP enoyl-CoA 1-carbonyl-CoA integrated transposon guanosine dependent guanosine pyruvate benzoyl-CoA a 1,2-diacyl-3-O-(β- UDP D-glucopyranose maltose in 23S rRNA carrier protein] in 16S rRNA IMP asp 5-phosphate aldolase: 3-hydroxypimeloyl-CoA an N-terminal L- 3-benzyl-3,6 -dithio- RS01705 pyrimidine/purine ribonucleoside- CDP amidophosphoribosyltransferase: purF hydratase: 6-oxocyclohex- a [glycine-cleavage complex H D-galactopyranosyl) dmpG degradation I (aerobic) 5'-deoxyadenosine Arg 3-hexaprenyl-4- pyruvate IMP met 6 an unsulfurated [sulfur carrier] a tRNA arginiyl-3-sulfo- 6-(hydroxymethyl) glutamine- nucleoside phosphorylase: diphosphate reductase: AzCIB_RS03180 1-ene-1- protein] N -[(R)-lipoyl]-L-lysine -sn-glycerol hydroxybenzoate adenosylcobalamin- β ribulose- ribose-5- 4-hydroxy-2- L-alanyl-[protein] -diketopiperazine hydrolyzing dehydrogenase: AzCIB_RS15550 5-phospho- - gly [+ 2 isozymes] carbonyl-CoA benzoyl-CoA adenylosuccinate AzCIB_RS14795 dependent phosphate 3- phosphate oxovalerate carbamoyl- guaB guanine dUDP D-ribosylamine guanine (3S)- hydratase: oah RS08960 synthase: ribonucleoside- epimerase: isomerase aldolase: benzoyl- phosphate hydroxyadipyl- [+ 2 isozymes] 3-oxopimeloyl-CoA methylgallate degradation an N-terminal 1402 AzCIB_RS03625 diphosphate reductase: AzCIB_RS18725 RpiA: rpiA CoA 2,3- a [pyruvate dehydrogenase E2 an N-terminal L- an isoprenoid a cytidine a 2'- synthase: XMP nucleoside-diphosphate phosphoribosylamine- dmpG CoA an L-arginyl- an L-arginyl- coenzyme A a nucleoside a holo [BryU acyl- butan-2-one 2-chloroacetate 1-butanal ethanol hypoxanthine-guanine hypoxanthine-guanine 3-hydroxypimeloyl- epoxidase: a sulfurated [sulfur carrier] SAM 6 3-sulfino-L- 4-hydroxybenzoate VibB a malonyl-[acp] RsxA kinase: AzCIB_RS03550 AzCIB_RS14795 protein] N -octanoyl-L-lysine aspartyl-[protein] [tRNA Arg ] [tRNA Arg ] diphosphate triphosphate in 16S rRNA carrier protein] deoxyribonucleoside carB carA phosphoribosyltransferase: -glycine ligase: purD phosphoribosyltransferase: peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis CoA alanyl-[protein] 16S rRNA acetone haloacid aldehyde lipid IV biosynthesis (P. putida) peptidoglycan maturation (meso-diaminopimelate containing) D-xylulose D-ribose 5- acetaldehyde 3-O-methylgallate 2,3-epoxy-2,3-boxB boxA deoxynucleoside catalase/ glutamine- dUTP dCDP A nucleotide ACP S- malonyl-ACP O- adenylo-succinate AzCIB_RS03715 AzCIB_RS03715 5-phosphate phosphate dihydrobenzoyl- (cytidine(1402)-2'-O) kinase: carboxylase: dehalogenase ferredoxin peroxidase α pyrophosphohydrolase: methyltransferase carbamoyl hydrolyzing GMP hypoxanthine-guanine dUTP diphosphatase: nucleoside-diphosphate GAR hypoxanthine-guanine UDP-N-acetyl- -D-glucosamine a (3R)-3- lipid II (meso acetaldehyde CoA 4-hydroxybenzoate holo-ACP -methyltransferase: malonyltransferase: AzCIB_RS20000 type II: oxidoreductase: asp glutaryl-CoA lipoyl synthase: lipA arginyltransferase: arginyltransferase: AzCIB_RS07710 AzCIB_RS17550 HPI: katG EpsF phosphate synthase: guaA adenylosuccinate diaminopimelate containing) dehydrogenase 3-oxoadipyl-CoA aromatic octaprenyltransferase: synthase: rsmI fabD a 2'- BioC: bioC AzCIB_RS20005 AzCIB_RS16280 AzCIB_RS14280 phosphoribosyltransferase: AzCIB_RS16375 kinase: AzCIB_RS03550 phosphoribosyltransferase: UDP-N-acetylglucosamine hydroxydecanoyl- UDP-N-acetyl- transketolase: tkt 2,3- AzCIB_RS09300 AzCIB_RS09300 a 2'-O- a malonyl- lyase: purB phosphoribosylglycinamide (acetylating): 3-oxopimeloyl- ring-opening [+ 2 isozymes] AzCIB_RS20905 AzCIB_RS13790 a nucleoside 5'- deoxyribonucleoside a malonyl-[acp] acetaldehyde AzCIB_RS21465 nucleotide dCTP AzCIB_RS21465 1-carboxyvinyltransferase: [acp] α-D-glucosamine monofunctional 3-oxoadipyl- epoxybenzoyl- methylcytidine 1402 [BryU acyl- 3-oxopentanoate glycolate butanoate FtsL GMP formyltransferase: AzCIB_RS07490 CoA monophosphate 5'-monophosphate methyl ester murA biosynthetic dioxygenase LigA: CoA an N-terminal in 16S rRNA carrier protein] aspartate pyrophosphohydrolase: AzCIB_RS17765 D-sedoheptulose D-glyceraldehyde CoA thiolase: acyl-ACP--UDP-N- peptidoglycan AzCIB_RS12110 dihydrolase: Arg an N-terminal L- carbamoyltransferase AMP GMP AzCIB_RS07710 GMP UDP-N-acetyl-α-D-glucosamine-enolpyruvate 7-phosphate 3-phosphate acetaldehyde AzCIB_RS09575 a [pyruvate dehydrogenase a tRNA L-arginiyl-L- a 4-hydroxy-3- a holo-[VibB aryl- 5'-deoxyadenosine Arg 3',5'-ADP acetylglucosamine O- transglycosylase: 6 a tRNA arginiyl-3-sulfino- catalytic subunit: guanylate kinase: xanthine and FGAR dehydrogenase [+ 2 isozymes] boxC met E2 protein] N -lipoyl-L-lysine an unsulfurated [sulfur carrier] aspartyl-[protein] polyprenylbenzoate carrier protein] dUMP UDP-N-acetylmuramate acyltransferase: lpxA mtgA 2-pyrone-4,6- cis-3,4- L-alanyl-[protein] RS07840 AzCIB_RS19440 AzCIB_RS01080 xanthosine salvage transaldolase: tal (acetylating): MeOH glutaryl-CoA dicarboxylate dehydroadipyl- adenylate kinase: thymidylate synthase: phosphoribosylformylglycinamidine dehydrogenase: murB a nascent peptidoglycan AzCIB_RS22035 succinyl-CoA CMP phosphorylation ala UDP-3-O-[(3R)-3- CoA semialdehyde RS09335 AzCIB_RS15610 AzCIB_RS15935 synthase: purL glu UDP-N-acetyl-α-D-muramate with (L-alanyl-γ-D-glutamyl- N-carbamoyl- D-erythrose UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N an N-terminal L- sn-glycero-3-phospho- 3,4-dihydroxyphenylacetyl- a 23S rRNA a cytidine 1402 a negatively an organic 3-hydroxy-5- GDP xanthosine hydroxydecanoyl]- F6P acetyl-CoA 3,4-dehydroadipyl- an L-arginyl- a holo [BryP acyl- 54 meso-2,6-diaminopimeloyl-D- γ glycerophosphoserine 1911/1915/1917 a uracil in tRNA a uridine in tRNA acetaldehyde L-aspartate dTMP CMP N-acetyl-α-D- 4-phosphate CoA semialdehyde -acetylmuramoyl-L-alanyl- - glutamyl-[protein] Arg N-(arachidonoyl) CoA uridine in 16S rRNA supercoiled DNA hydroperoxide methyl-benzoate pyrimidine/purine FGAM glutamate racemase: (1E)-4-oxobut- [tRNA ] carrier protein] ADP bifunctional 3- UDP-N-acetylmuramate- alanyl-D-alanine) pentapeptide D-glutamyl-L-lysyl- D-alanine ethanolamine 23S rRNA 16S rRNA DNA tRNA tRNA aldehyde alkyl dihydroorotase: dTMP kinase: tmk nucleoside glucosamine dehydrogenase: ACP S- RS01700 AzCIB_RS16480 -L-alanine ligase: transketolase: tkt cinnamate and 3-hydroxycinnamate 1-ene-1,2,4- pseudouridine(1911/ (cytosine(1402)-N(4) topoisomerase (uridine(54)-C5)- dihydrouridine ferredoxin hydroperoxide dTMP kinase: phosphoribosylformylglycinamidine phosphoshikimate 1- UDP-3-O-acyl-N- diphenyl ethers AzCIB_RS23070 undecaprenyldiphospho- hydroxyphenylacetyl- pyrC nucleoside- adenosylcobalamin- phosphorylase: AzCIB_RS18920 penicillin-binding penicillin-binding tricarboxylate glycerophosphodiester 1915/1917) )-methyltransferase malonyltransferase: IV subunit A: parC synthase reductase: adenosylcobalamin- carboxyvinyltransferase/ acetylglucosamine degradation degradation to 2-hydroxypentadienoate cis-3,4- muramoylpentapeptide beta-N- arginyltransferase: methyltransferase oxidoreductase: dihydroorotase: diphosphate dependent AzCIB_RS14020 AzCIB_RS15550 cyclo-ligase: purM protein 2: mrdA protein 2: D-glyceraldehyde glycerophosphodiester CoA thioesterase fabD RS07875 dependent xanthine cytidylate kinase: D-glt deacetylase: toluene degradation to dehydroadipyl- acetylglucosaminyltransferase: AzCIB_RS09300 phosphodiesterase: ugpQ synthase RluD: rluD 4 RsmH: rsmH [+ 2 isozymes] TrmA: trmA DusB: dusB AzCIB_RS14280 ahpC ahpF phosphodiesterase: ugpQ PaaI: paaI 1911/ an N - a malonyl- 54 AzCIB_RS19445 kinase: ribonucleoside- ribonucleoside- dTDP UDP-N-acetyl-α-D-muramoyl-L-alanine D-alanyl-D-alanine AzCIB_RS18955 a mature peptidoglycan with 3-phosphate benzoyl-CoA (anaerobic) cinnamate CoA a pseudouridine a 5-methyluracil a 5,6-dihydrouridine 3-methylgentisate AIR AzCIB_RS18075 AzCIB_RS18895 diphenyl ether murG methylcytidine 1402 [BryP acyl- a relaxed DNA acetate an alcohol AzCIB_RS03550 diphosphate carboxypeptidase/ [+ 2 isozymes] (L-alanyl-γ-D-glutamyl-meso- 1915/1917 in 23S rRNA in tRNA in tRNA (S)-dihydroorotate diphosphate nucleoside-diphosphate CDP UDP-3-O-(3- (1E,3E)-4- an N-terminal in 16S rRNA carrier protein] reductase: UDP-N-acetylmuramoyl- D-alanyl-D-alanine- 2,6-diaminopimeloyl-D-alanyl- toluene 3-phenylpropionate/ sn-glycerol (3,4- reductase: inosine-5'-phosphate biosynthesis I kinase: AzCIB_RS03550 hydroxydecanoyl) hydroxybuta- ditrans,octacis-undecaprenyldiphospho- UDP Arg RsxB superpathway of pyrimidine nucleoside-diphosphate a nascent peptidoglycan D-alanine) pentapeptide a tRNA L-arginiyl-L- anandamide ser coenzyme A dihydroxyphenyl) AzCIB_RS14795 AzCIB_RS14795 L-alanine--D- -α-D-glucosamine endopeptidase: dacB benzylsuccinate cinnamic acid 1,3-diene-1,2,4- N-acetyl-(N-acetylglucosaminyl)muramoyl- sn-glycerol 3-phosphate 3-phosphate quinone- dTTP nucleobases salvage kinase: AzCIB_RS03550 with D,D cross-links (meso- trans-2,3- glutamyl-[protein] acetate GTP glutamate ligase: murD UDP-3-O-(3- synthase: dioxygenase tricarboxylate L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine RS04410 dependent AIR XMP a nascent peptidoglycan diaminopimelate containing) (1S,2S)-3- dehydroadipyl-coA uracil CTP hydroxymyristoyl) AzCIB_RS23980 subunit beta: dihydroorotate dADP meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- γ phenoxycyclohexa- dGDP glucosamine N- with (L-alanyl- -D-glutamyl- AzCIB_RS22450 AzCIB_RS12060 enoyl-CoA 5-(carboxyamino) bifunctional pyr operon 3,5-diene-1,2-diol undecaprenyl-diphospho-N-acetylmuramoyl-L- an N 1 - 1939 RNase G a [protein]- dehydrogenase: L-alanyl-D-glutamate meso-2,6-diaminopimeloyl- (R)-2-benzylsuccinate (2E)-3-(5,6- hydratase: UDP-N-acetyl-α-D-glucosamine a single- a uracil 3-hydroxy-4- nucleoside- imidazole ribonucleotide transcriptional regulator/uracil acyltransferase: γ 2-oxoglutarate coenzyme A AsbD acyl- coenzyme A dihydrolipoamide a [protein] Ser/Thr degradation crotonaldehyde formaldehyde AzCIB_RS09305 D-alanine) tetrapeptide cis-2,3- 2-hydroxy-4- alanyl- -D-glutamyl-L-lysyl- D-alanyl-D-alanine ethyladenine stranded RNA thr in 23S rRNA N-phospho- methyl-benzoate RS07820 synthase: AzCIB_RS04965 lpxD a mature peptidoglycan dihydroxycyclohexa- AzCIB_RS03180 carrier protein PRPP nucleoside- diphosphate kinase: phosphoribosyltransferase D-ala UDP-N-acetylmuramoyl- dihydrobiphenyl- oxobutane-1,2,4- in DNA dihydrolipoyllysine- serine/threonine 23S rRNA substrate mRNA aldehyde aldehyde L-histidine orotate UDP-2-N-[(3R)-3- with D,D cross-links (meso- 1,3-dien-1-yl) [+ 2 isozymes] undecaprenyldiphospho- threonine ammonia- phosphohistidine diphosphate AzCIB_RS03550 PyrR: pyrR L-alanyl-D-glutamate-- 2,3-diol tricarboxylate residue protein kinase: (uracil(1939)-C(5)) ribonuclease G: ferredoxin ferredoxin RS09830 N5-CAIR hydroxydodecanoyl]- diaminopimelate containing) prop-2-enoate (3S)- muramoylpentapeptide beta-N- lyase, biosynthetic: ilvA phosphatase: kinase: uracil 2, 6-diaminopimelate dehydrogenase: DNA oxidative holo-ACP polyribonucleotide CoA pyrophosphatase: acetyltransferase: AzCIB_RS13475 -methyltransferase AzCIB_RS02355 oxidoreductase: oxidoreductase: orotate D-alanine--D-alanine 3-O-[(3R)-3- hydroxyadipyl- acetylglucosaminyltransferase: threonine ammonia- AzCIB_RS04530 AzCIB_RS03550 dATP superpathway of pyrimidine deoxyribonucleoside salvage phosphoribosyltransferase: ligase: AzCIB_RS18915 ligase: AzCIB_RS18950 a nascent peptidoglycan a nascent peptidoglycan with a nascent peptidoglycan a mature peptidoglycan (R)-benzylsuccinyl-CoA bphB demethylase synthase: nucleotidyltransferase: pnp AzCIB_RS15490 aceF [+ 4 isozymes] RlmD: rlmD AzCIB_RS14280 AzCIB_RS14280 phosphoribosyltransferase: 5-(carboxyamino)imidazole hydroxydecanoyl]- cis-3-(2- CoA murG lyase: AzCIB_RS21805 1939 a [protein]- AzCIB_RS21460 γ γ γ AlkB: alkB AzCIB_RS13790 a [protein] (L-serine/L- a 5-methyluracil an mRNA fragment 4-methylgentisate pyrE ribonucleotide mutase: purE α with L,D cross links (meso- (L-alanyl- -D-glutamyl-meso- with (L-alanyl- -D-glutamyl- with (L-alanyl- -D-glutamyl- diphenyl carboxyethenyl) S-acetyldihydrolipoamide crotonate formate dGTP UMP UDP-N-acetyl-α-D-muramoyl-L-alanyl- -D-glucosamine 2-oxobutanoate threonine) phosphate in 23S rRNA L-histidine LivM 2'-deoxycytidine D-alanyl-D-alanine diaminopimelate containing) 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- meso-2,6-diaminopimeloyl- ether 2,3-diol -3,5- oxaloacetate asp γ-D-glutamyl-meso-2,6-diaminopimelate UDP-2,3- ditrans,octacis-undecaprenyldiphospho-N- UDP a nucleoside a single- CAIR UMP kinase: glycine) tetrapeptide D-alanine) tetrapeptide cyclohexadiene- a holo-[AsbD acyl- 3',5'-ADP 4'-phosphopantetheine orotidine 5'- diacylglucosamine 3-hydroxycinnamate acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- acetaldehyde an adenine in DNA succinate 3',5'-ADP diphosphate stranded RNA RS09890 1,2-diol 3-oxoadipyl-CoA carrier protein] phosphate AzCIB_RS10975 UDP-N-acetylmuramoyl- diphosphatase: (E)-2- alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine bifunctional 3- tripeptide--D-alanyl-D- AzCIB_RS17215 a mature peptidoglycan a mature peptidoglycan with benzylidenesuccinyl-CoA dehydrogenase: phosphoribosylaminoimidazolesuccinocarboxamide (2Z,4E)-2- 3-oxoadipyl- orotidine-5'- 2'-deoxyuridine dCMP phosphoshikimate 1- alanine ligase: murF with L,D cross-links (meso- (L-alanyl-γ-D-glutamyl-meso- a mature peptidoglycan AzCIB_RS12075 synthase: AzCIB_RS04160 UDP-2,3- hydroxy-6-oxo- pyruvate 1 purine deoxyribonucleosides salvage CoA thiolase: an N - an N 3 -methyladenine a nucleoside 4-(2'- RS21660 phosphate bifunctional 3- carboxyvinyltransferase/ diaminopimelate containing) 2,6-diaminopimelate) tripeptide with (L-alanyl-γ-D-glutamyl- dethiobiotin a sulfurated coenzyme A [EntB aryl- (9Z,12Z,15Z,18Z,21Z)-3- a D-hexose diacylglucosamine 6-phenoxyhexa- AzCIB_RS09575 2-oxoglutarate methyladenine glycerophosphoglycerol cyclic 3',5'- carboxyphenyl)- 3-oxopropanoate coniferaldehyde rhodopin D-glycerate ferroheme o decarboxylase: deoxynucleoside UDP-N-acetyl-α-D-muramoyl-L- meso-2,6-diaminopimeloyl- 2,3-dihydroxy- phenol degradation SAM in DNA oxotetracosapentaenoyl-CoA phosphoshikimate 1- cytidylate kinase: diphosphatase: 2,4-dienoate [sulfur carrier] carrier protein] pyrF SAICAR kinase: alanyl-γ-D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate 2-carboxymethyl-3- [+ 2 isozymes] in DNA monophosphate 4-oxobutyryl-CoA malonic coniferyl aldehyde carotenoid 2-hydroxy-3- RS09995 carboxyvinyltransferase/ AzCIB_RS18075 glycine) tetrapeptide trans-cinnamate II (anaerobic) 3',5'-cyclic-nucleotide dihydroxynaphthoic glucokinase: 2'-deoxyguanosine 2'-deoxyadenosine AzCIB_RS17550 diaminopimeloyl-D-alanyl-D-alanine AzCIB_RS15035 hydroxyphenylpropanoyl-CoA acetoacetyl-CoA semialdehyde dehydrogenase: 1,2-hydratase: oxopropionate UMP thymidine cytidylate kinase: succinyl-CoA DNA-3- phosphodiesterase: acid synthetase: AzCIB_RS06505 deoxynucleoside deoxynucleoside adenylosuccinate UDP biotin DNA oxidative holo-ACP glycerophosphodiester reductase: phbB reductase: reductase: AzCIB_RS18075 lipid X (P. putida) phenol methyladenine AzCIB_RS12340 AzCIB_RS07460 AzCIB_RS13080 lyase: purB phenylacetate synthase demethylase synthase: phosphodiesterase: ugpQ AzCIB_RS18735 AzCIB_RS19890 UMP kinase: kinase: kinase: dUMP nucleoside-diphosphate phospho-N-acetylmuramoyl- phenylphosphate Carbohydrate Degradation (3R,9Z,12Z,15Z,18Z,21Z)-3- AzCIB_RS20980 D-hexose 6- RS09820 deoxynucleoside 2-pyrone-6- (2Z,4E,7E)-2- degradation glycosylase I: tag a nucleoside 5'- 1,4-dihydroxy-2- ferulate all-trans-lycopene tartronate ferroheme a AzCIB_RS10975 AzCIB_RS17550 AzCIB_RS17550 dCDP kinase: AzCIB_RS03550 pentapeptide- transferase: lipid-A- phenol synthase BioB: bioB AlkB: alkB AzCIB_RS13790 hydroxytetracosapentaenoyl-CoA 3-hydroxypropanoate phosphate AICAR kinase: naphthoyl-CoA semialdehyde dGMP dAMP thymidylate AzCIB_RS18940 disaccharide carboxylate hydroxy-6-oxonona- II (anaerobic) monophosphate bifunctional 3- nucleoside- benzoylsuccinyl-CoA subunit beta: Entner-Doudoroff pathway I HflB synthase: AzCIB_RS17550 UTP adenine and 2,4,7-triene-1,9-dioate glycerol sn-glycerol an apurinic site phosphoshikimate 1- bifunctional synthase: lpxB AzCIB_RS13280 phenylacetate biotin 5'-deoxyadenosine an unsulfurated a holo-[EntB aryl- 3-methyladenine AzCIB_RS15935 diphosphate kinase: undecaprenyldiphospho-N-acetylmuramoyl- benzoylsuccinyl- met an adenine in DNA formaldehyde succinate 3',5'-ADP 3-phosphate carboxyvinyltransferase/ CTP synthase: adenosine salvage I lipid A phenyl phosphate phenylacetate-- [sulfur carrier] carrier protein] within DNA phosphoribosylaminoimidazolecarboxamide AzCIB_RS03550 L-alanyl-γ-D-glutamyl-meso-2,6- CoA thiolase: D-glucopyranose cytidylate kinase: AzCIB_RS09765 disaccharide CoA ligase: paaF formyltransferase/IMP cyclohydrolase: purH diaminopimeloyl-D-alanyl-D-alanine AzCIB_RS22550 6-phosphate RS19360 dCTP (P. putida) phenylphosphate AzCIB_RS18075 CTP adenosine (2Z)-2-hydroxypenta- phenylacetate-- FAICAR undecaprenyldiphospho- glucose-6- 3 α tetraacyldisaccharide benzoyl-CoA 2,4-dienoate carboxylase: ppcB CoA ligase: paaF an N - sn-glycero-3- S-(2-hydroxyacyl) (9Z,12Z,15Z,18Z)-3- a double-stranded (3Z)-hex- GDP- -D- UDP pyrimidine/purine muramoylpentapeptide beta-N- phosphate glutathione 2-oxoglutarate coenzyme A [EntF L-seryl- uroporphyrinogen-III uroporphyrinogen-I wound RNA D-glycerate chitosan CysW dGDP dADP 4'-kinase: ppcD ppcA ppcG phenylacetyl-CoA a phytochelatin methylcytosine phosphoethanolamine glutathione oxotetracosatetraenoyl-CoA oligonucleotide 3-en-1-ol mannose bifunctional dTMP nucleoside phosphorylase: acetylglucosaminyltransferase: dehydrogenase: carrier protein] nucleoside- AzCIB_RS15625 in DNA uroporphyrinogen-III uroporphyrinogen CHAT domain- RNA helicase: 2-hydroxy-3- GDP- phosphoribosylaminoimidazolecarboxamide AzCIB_RS15550 murG 4-hydroxybenzoate zwf oligoribonuclease: diphosphate nucleoside- nucleoside- dTMP kinase: tmk lipid IV 3-chlorobenzoate acetoacetyl-CoA C-methyltransferase: oxopropionate mannose 4,6- formyltransferase/IMP cyclohydrolase: purH adenine A 6-phospho decarboxylase: containing protein: AzCIB_RS09645 diphosphate diphosphate (P. putida) degradation III glutathione gamma- DNA oxidative holo-ACP glycerophosphodiester hydroxyacylglutathione reductase: phbB cobA AzCIB_RS14550 reductase: dehydratase: RS09955 kinase: dTMP kinase: lipid II (meso diaminopimelate containing) D-glucono- AzCIB_RS23425 AzCIB_RS05105 [+ 2 isozymes] kinase: kinase: (via gentisate) glutamylcysteinyltransferase: demethylase synthase: phosphodiesterase: ugpQ hydrolase: gloB [+ 2 isozymes] AzCIB_RS19890 gmd a chitosan AzCIB_RS03550 AzCIB_RS14020 adenine phenylglyoxylyl- 1,5-lactone (3R,9Z,12Z,15Z,18Z)-3- a nucleoside 5'- (3Z)-hex-3- GDP-4-dehydro- gln IMP AzCIB_RS15600 AlkB: alkB AzCIB_RS13790 coproporphyrinogen I an unwound RNA tartronate fragment AzCIB_RS03550 AzCIB_RS03550 phosphoribosyltransferase: 3-chlorobenzoate CoA hydroxytetracosatetraenoyl-CoA precorrin-2 monophosphate en-1-yl acetate α-D-rhamnose FliJ UTP dTDP 4-hydroxybenzoyl- 6-phosphogluconolactonase: semialdehyde AzCIB_RS03720 a holo-[EntF a 2-hydroxy dGTP dATP nucleoside- CoA pgl ethanolamine sn-glycerol glutathione CTP synthase: a cytosine in DNA formaldehyde succinate 3',5'-ADP carboxylate diphosphate kinase: 4-hydroxybenzoyl- D-gluconate gly a phytochelatin L-seryl-carrier 3-phosphate AzCIB_RS09765 AMP 3-hydroxybenzoate protein] PstC AzCIB_RS03550 CoA reductase: phenylglyoxylate 6-phosphate AzCIB_RS08980 CTP dTTP phosphogluconate RS19670 4-hydroxybenzoyl- dehydratase: 5-amino-4- (R)-2- RNase R degradation a 5' triphospho- a cytosine 967 Reactive Blue 5 PRPP acetyl-CoA maltohexaose oxaloacetate an acyl phosphate a folate D-glycerate an aldehyde malonyl-CoA CoA reductase: AzCIB_RS06300 imidazolecarboxyamide hydroxyglutarate substrate RNA [mRNA] in 16S rRNA gentisate hcrB hcrA hcrC RNA 16S rRNA phosphoenolpyruvate dihydrofolate D-glycerate aldehyde malonyl-CoA benzoyl-CoA KDGP pyrophosphohydrolase: (cytosine(967)-C(5) acylphosphatase: reductase: dehydrogenase: ferredoxin decarboxylase: Dyp-type adenine glutaconate CoA- alpha-glucosidase: carboxykinase (GTP) CysA benzoyl-CoA ribonuclease )-methyltransferase AzCIB_RS15975 oxidoreductase: phosphoribosyltransferase: AzCIB_RS04600 : AzCIB_RS02650 AzCIB_RS15940 AzCIB_RS14630 AzCIB_RS19620 peroxidase: transferase: AzCIB_RS21060 RS19685 R: rnr a 5'-phospho- RsmB: rsmB phosphoenol AzCIB_RS14280 bifunctional AzCIB_RS09505 AzCIB_RS03720 AzCIB_RS10405 a 5-methylcytosine 967 a 7,8-dihydrofolate hydroxypyruvate acetyl-CoA [mRNA] pyruvate a carboxylate a carboxylate 4-hydroxy-2- in 16S rRNA 3-[(4-amino-6-chloro- (R)-2- D-glucopyranose maltopentaose Nucleoside and Nucleotide Degradation oxoglutarate 2,2'-disulfonyl a diribonucleotide a nucleoside 5'- 1,3,5-triazin-2-yl) phthalate AICAR hydroxyglutaryl- acetate RS04810 aldolase/2- azobenzene monophosphate dehydro-3-deoxy- amino]benzenesulfonate CoA inosine 5'- RS20740 phosphogluconate phosphate guanosine purine ribonucleosides degradation UTP and CTP dephosphorylation I aldolase: eda a methylated 55 a [protein]- degradation nucleotides an L-1- an (S-diacyl-sn- (3R,7Z,10Z,13Z,16Z)-3- 3-heptaprenyl-4- a uridine glycyl-glycine glutathione 2-oxoglutarate (E)-glutaconate acetyl-CoA maltoheptaose 2-phosphoglycolate a cytosine in DNA D-glycerate π pyruvate degradation III UTP phosphatidylethanolamine glyceryl)-L-cysteinyl- nucleobase hydroxydocosatetraenoyl-CoA hydroxybenzoate in tRNA N -phospho- D-glyceraldehyde adenosine [apolipoprotein] within DNA 4-hydroxy-3- tRNA phosphoglycolate D-glycerate L-histidine pyruvate RS02305 IMP pyruvate DNA methylase: phosphohistidine GMP CTP synthase: 3-phosphate acetoacetyl-CoA IMP glutaconate CoA- polyprenylbenzoate pseudouridine(55) phosphatase: dehydrogenase: phosphatase: carboxylase: AzCIB_RS09765 gamma- DNA oxidative alpha-glucosidase: reductase: phbB AzCIB_RS06705 RS05265 pyrimidine 5'- type I apolipoprotein N- transferase: decarboxylase: ubiD synthase TruB: truB AzCIB_RS18720 AzCIB_RS14630 AzCIB_RS05860 dehydrogenase: glutamyltransferase: ggt demethylase AzCIB_RS21060 AzCIB_RS04530 guaB nucleotidase: UDP glyceraldehyde- acyltransferase: lnt AzCIB_RS10405 (7Z,10Z,13Z,16Z)-3- a pseudouridine 55 a 5-methylcytosine a [protein]- CTP AlkB: alkB 2-heptaprenylphenol glycolate hydroxypyruvate oxaloacetate XMP AzCIB_RS04310 3-phosphate oxodocosatetraenoyl-CoA in tRNA in DNA L-histidine dehydrogenase: D-mannose degradation 5'/3'-nucleotidase an N-acyl-(S-diacyl- γ D-glucopyranose RS05025 gap a 2-acyl-1-lyso- -L-glutamyl- L-cysteinylglycine a nucleobase (E)-glutaconyl- maltohexaose pyrimidine 5'- SurE: surE xanthosine adenosine inosine guanosine sn-glyceryl)-L- formaldehyde succinate acetate UMP phosphatidylethanolamine glycylglycine CoA nucleotidase: guanosine aldehyde D-mannopyranose cysteinyl-[lipoprotein] within DNA TrkD CDP 6-phosphate AzCIB_RS04310 pyrimidine 5'- dehydrogenase: mannose-1-phosphate pyrimidine/purine AzCIB_RS03080 5'/3'-nucleotidase pyrimidine/purine pyrimidine/purine pyrimidine/purine pyrimidine/purine nucleotidase: guanylyltransferase/ 6 DNA combined with a [protein]- + a [histone]-N - α 7,8-dihydrofolate + (2R)-phospho- 3-nonaprenyl-4- adenosyl-cob(III) γ-glutamyl- nucleoside UDP-N-acetyl- -D-muramoyl- maltopentaose τ SurE: surE nucleoside nucleoside nucleoside nucleoside AzCIB_RS04310 mannose-6- NAD D-alanyl-D-alanine NADPH H exogenous DNA to form chlorobactene rhodopin N -phospho- γ-carotene acetyl-L-lysine L-alanyl-γ-D-glutamyl-L-lysine monoglutamate 3-sulfolactate hydroxybenzoate yrinate a,c-diamide isopropylamide RS10585 phosphorylase: phosphorylase: phosphorylase: phosphorylase: phosphorylase: CMP 13-DPG phosphate isomerase: 5'/3'- a recombinational junctionHolliday junction 2-phosphosulfolactate 4-hydroxy-3- carotenoid carotenoid cobyric acid ferredoxin: L-histidine carotenoid AzCIB_RS15550 AzCIB_RS15550 AzCIB_RS15550 AzCIB_RS15550 AzCIB_RS15550 AzCIB_RS15260 phosphohistidine xanthosine pyrimidine 5'- nucleotidase phosphatase: polyprenylbenzoate 1,2-hydratase: 1,2-hydratase: synthase: 1,2-hydratase: MotA phosphoglycerate NAD-dependent UDP-N-acetylmuramoyl- dihydrofolate resolvase RuvX: ruvX alpha-glucosidase: AzCIB_RS07980 phosphatase: nucleotidase: SurE: surE mannose-1-phosphate AzCIB_RS09655 decarboxylase: ubiD AzCIB_RS13080 AzCIB_RS13080 AzCIB_RS20610 AzCIB_RS13080 guanine α kinase: pgk deacylase: tripeptide--D-alanyl-D- reductase: crossover junction AzCIB_RS21060 [+ 2 isozymes] AzCIB_RS04530 -D-ribose- AzCIB_RS04310 pyrimidine/purine uridine guanylyltransferase/ endodeoxyribonuclease 1,1'-dihydroxy-1,1',2,2'- N-(γ-L-glutamyl) a [protein]- 1'-hydroxy- 1-phosphate 3-phospho- AzCIB_RS21405 alanine ligase: murF AzCIB_RS15940 (2R)-3-sulfolactate 2-nonaprenylphenol 1-hydroxychlorobactene adenosylcobyrate nucleoside 5'/3'- mannose-6- resolution of recombinationalRuvC: ruvC tetrahydrolycopene -L-alaninol L-histidine γ-carotene RS10700 guanine D-glycerate phosphate isomerase: phosphorylase: nucleotidase α junction formation NAD(P) 2''-O-acetyl- UDP-N-acetyl- -D-muramoyl-L-alanyl- 5,6,7,8- D-glucopyranose maltotetraose + + AzCIB_RS15550 deaminase: guaD SurE: surE 2,3- AzCIB_RS19190 a [histone]-L-lysine nicotinamide NADP + H H ADP-ribose γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine tetrahydrofolate of two intact strands transhydrogenase D-ribose 5- diphosphoglycerate- F6P xanthine cytidine xanthine phosphate dependent phosphoglycerate 6 xanthine:NAD+ xanthine:NAD+ 6 an N -L- N,N',N''- an [amino-group carrier protein]- N,N'- α F0F1 ATP + a [protein]-N - poly-[(R)-3- a 4-hydroxy-3- (6R)-L-erythro-5,6,7,8- (2R,3S)-3- a [protein] (L-serine/L- CDP- -D-glucose + + mutase: gpmA NAD threonylcarbamoyladenine 37 triacetylchitotriose C-terminal-γ-(L-glutamate 5- 1-hydroxyneurosporene D-glucopyranose H H RS15670 oxidoreductase: oxidoreductase: pyrimidine deoxyribonucleotides acetyl-L-lysine hydroxybutanoate] diacetylchitobiose polyprenylbenzoate tetrahydrobiopterin isopropylmalate threonine) phosphate CDP- synthase hcrA hcrA dephosphorylation 2-phospho- in tRNA semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- beta-N- 4-hydroxy-3- carotenoid pteridine 3-isopropylmalate glucose 1- pyrimidine deoxyribonucleosides degradation S-methyl-5'- tRNA protein glucose 4,6- nucleotide D-glycerate beta-N- glutamyl-phosphate acetylhexosaminidase: polyprenylbenzoate 1,2-hydratase: reductase: dehydrogenase: dehydrogenase: urate urate thioadenosine NAD-dependent threonylcarbamoyladenosine phosphatase dehydratase: pyrophosphohydrolase: phosphopyruvate reductase: nagZ AzCIB_RS07480 2'-deoxycytidine deacylase: dehydratase: AzCIB_RS19940 acetylhexosaminidase: decarboxylase: ubiD AzCIB_RS13080 AzCIB_RS21370 leuB CheZ: cheZ rfbG degradation III 6 N-acetyl-D- AzCIB_RS07710 hydratase: a cyclic N -L- nagZ an [amino-group carrierAzCIB_RS04645 protein]- a 2-(all-trans- all-trans 4-methyl-2- D-glucono- dCMP S-methyl-5'- AzCIB_RS21405 L-erythro-biopterin CDP-4-dehydro-6- dCTP AzCIB_RS09755 threonylcarbamoyladenosine glucosamine 1,5-lactone a [protein] Ser/Thr MotB thioadenosine C-terminal-γ-(5-phospho- polyprenyl)phenol neurosporene oxopentanoate deoxy-α-D-glucose phosphoenol 37 in tRNA 2''-O-acetyl- (R)-3- poly-[(R)-3- N,N'- N-acetyl-D- L-glutamyl)-L-glutamate dUTP diphosphatase: pyruvate nicotinamide a [protein]-L-lysine diacetylchitobiose glucosamine 2'-deoxyuridine thymidine S-methyl-5'- ADP-ribose hydroxybutanoate hydroxybutanoate] AzCIB_RS16375 pyruvate pyrimidine/purine thioinosine nucleotide pyrimidine/purine kinase: pyk pyrophosphohydrolase: nucleoside S-methyl-5'- nucleoside pyruvate 3-methyl-2- 5,10-methylene- 2-amino-6-[1-hydroxyethyl]- a 5-carboxymethylaminomethyluridine 34 a pseudouridine 1915 dCDP 3-decaprenyl-4- an organic dCTP LptG AzCIB_RS07710 phosphorylase: thioinosine a sialyloligosaccharide 1-hydroxyneurosporene N-ethylmaleimide a thiopurine D-glucopyranose phosphorylase: kinase: pyk oxobutanoate tetrahydromethanopterin in tRNA Leu in 23S rRNA hydroperoxide dUTP dUMP AzCIB_RS15550 phosphorylase: 7-methyl-7,8-dihydropterin adenosylcobalamin- hydroxybenzoate AzCIB_RS15550 2-amino-4-hydroxy-6- tRNA (cytidine(34) 23S rRNA 4-hydroxy-3- carotenoid alkene reductase: thiopurine S- glucose 1- dCTP deaminase: AzCIB_RS13620 pyruvate dependent ribonucleoside- thiol peroxidase: thymine 3-methyl-2-oxobutanoate hydroxymethyldihydropteridine -2'-O)- (pseudouridine(1915)- polyprenylbenzoate 1,2-hydratase: AzCIB_RS06460 methyltransferase: dehydrogenase: AzCIB_RS15950 exo-alpha-sialidase: diphosphate reductase: AzCIB_RS00305 methyltransferase: N(3))-methyltransferase decarboxylase: ubiD AzCIB_RS13080 [+ 2 isozymes] tmpT AzCIB_RS07480 5-hydroxy-CTP 5-hydroxy-CMP 5-MTR-1-P hydroxymethyltransferase: diphosphokinase: folK AzCIB_RS02915 AzCIB_RS14795 dUTP panB [1-(2-amino-7-methyl-4-oxo- AzCIB_RS04330 3 RlmH: rlmH 1,1'-dihydroxy- a thiopurine D-glucono- a 5-carboxymethylaminomethyl- an N - CDP 2-decaprenylphenol N-ethylsuccinimide an alcohol 7,8-dihydro-3H-pteridin- 1915 34 Leu methylpseudouridine neurosporene S-methylether 1,5-lactone 6-yl)]ethyl diphosphate 2'-O-methyluridine in tRNA N-acetylneuraminate an oligosaccharide in 23S rRNA uracil 2-deoxy-α- 2-dehydropantoate THMPT purine deoxyribonucleosides degradation I D-ribose 1- phosphate

2,5-diamino-6-(5- 10 UDP CDP-4-dehydro-3,6- 2'-deoxycytidine CTP phosphatidylglycerolphosphate 4a-hydroxy-N - a double 2-hydroxychromene- D-ribulose maltose (2R,3S)-3- a supercoiled 2'-deoxyinosine 2'-deoxyadenosine 2'-deoxyguanosine phospho-D-ribitylamino) dideoxy-α-D-glucose (1-oleoyl, 2-palmitoyl) formyltetrahydrofolate stranded DNA 2-carboxylate adenosylcobalamin- 5-phosphate isopropylmalate deoxynucleoside duplex DNA pyrimidin-4(3H)-one 2-hydroxychromene- CDP-6-deoxy-delta- dCTP deaminase: bifunctional dependent ribonucleoside- 3-isopropylmalate kinase: helicase: phosphatidylglycerophosphatase 4a-hydroxytetrahydrobiopterin exodeoxyribonuclease 2-carboxylate 3,4-glucoseen phosphoribulokinase: alpha-glucosidase: AzCIB_RS15950 diaminohydroxyphosphoribosylaminopyrimidine diphosphate reductase: AzCIB_RS21060 dehydratase: AzCIB_RS17550 AzCIB_RS06700 pyrimidine/purine pyrimidine/purine pyrimidine/purine A: AzCIB_RS21275 dehydratase: AzCIB_RS10730 V: recC recB recD isomerase: reductase: AzCIB_RS04240 deaminase/5-amino-6-(5-phosphoribosylamino) AzCIB_RS14795 leuD leuC [+ 2 isozymes] nucleoside nucleoside nucleoside AzCIB_RS21825 AzCIB_RS19495 dCMP UTP uracil reductase RibD: ribD 1-oleoyl-2-palmitoyl- an N 10 -formyl- CDP-4-dehydro-6- D-ribulose-1,5- D-glucopyranose (2S)-2- a single phosphorylase: phosphorylase: phosphorylase: 5-amino-6-(5-phospho- a 5'-phosphooligonucleotide trans-O- dUDP phosphatidylglycerol 7,8-dihydrofolate deoxy-α-D-glucose bisphosphate isopropylmalate stranded DNA AzCIB_RS15550 AzCIB_RS15550 AzCIB_RS15550 D-ribitylamino)uracil hydroxybenzylidenepyruvate

2-deoxy-α-D- ribose 1-phosphate a reduced plastocyanin a reduced plastocyanin an oxidized an oxidized plastocyanin lipid II (meso plastocyanin diaminopimelate containing)

cytochrome- cytochrome RS11115 RS02680 RS02685 RS00345 SecY RS22400 RS16310 RS06015 RS11560 RS21665 CorA RS03035 RS11845 RS06400 RS22910 RS16950 RS23050 RS08290 RS12440 RS08490 RS01195 TatC RS06370 RS09035 SecF RS14130 RS19045 RS08045 RS09910 RS10185 FliF RS22290 RS15635 HtpX RS10910 RS05180 RS05020 FliP ChrA RS14705 RS01910 FtsW FtsA RS13930 ZipA RS18290 RS13085 RS17685 RS03385 TatB RS00800 RS00755 RS22970 RS22890 RS16735 RS11840 RS20335 RS06205 RodA RS06025 RS06005 RS11395 RS05935 Cls RS05735 ArsB c oxidase, c oxidase cbb3-type

lipid II (meso diaminopimelate O containing) O 2 2 H O H O 2 2 This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.