TGF Beta 1 Recombinant Protein Cat

TGF Beta 1 Recombinant Protein Cat. No.: 96-716 TGF Beta 1 Recombinant Protein Specifications SPECIES: Human SOURCE SPECIES: HEK293 cells SEQUENCE: Ala 279 - Ser 390 FUSION TAG: Tag free TESTED APPLICATIONS: WB APPLICATIONS: This recombinant protein can be used for WB. For research use only. PREDICTED MOLECULAR 12.8 kDa (monomer) WEIGHT: Properties >95% as determined by SDS-PAGE. PURITY: Less than 1.0 EU per μg by the LAL method. PHYSICAL STATE: Lyophilized BUFFER: TFA and acetonitrile September 28, 2021 1 https://www.prosci-inc.com/tgf-beta-1-recombinant-protein-96-716.html Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon STORAGE CONDITIONS: reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles. Additional Info OFFICIAL SYMBOL: Tgfb1 ALTERNATE NAMES: TGFB1, CED, DPD1, LAP, TGFβ1 , TGF-beta ACCESSION NO.: P01137-1 GENE ID: 21803 Background and References Transforming growth factor beta 1 (TGFB1) is also known as TGF-β1, CED, DPD1, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The TGFB1 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self- destruction of cells (apoptosis). The TGFB1 protein is found throughout the body and plays a role in development before birth, the formation of blood vessels, the regulation of BACKGROUND: muscle tissue and body fat development, wound healing, and immune system function. TGFB1 is particularly abundant in tissues that make up the skeleton, where it helps regulate bone growth, and in the intricate lattice that forms in the spaces between cells (the extracellular matrix). Within cells, this protein is turned off (inactive) until it receives a chemical signal to become active. TGFB1 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Most immune cells (or leukocytes) secrete TGFB1. TGFB1 has been shown to interact with TGF beta receptor 1, LTBP1, YWHAE, EIF3I and Decorin. REFERENCES: 1) Ghadami M, et al., 2000, Am. J. Hum. Genet. 66 (1): 143–7. 2) Assoian R, et al., 1983, J Biol Chem , 258 (11): 7155–60. 3) Derynck R, et al., 1985, Nature 316 (6030): 701–5. 4) Letterio J, Roberts A, 1998, Annu Rev Immunol 16: 137–61. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 28, 2021 2 https://www.prosci-inc.com/tgf-beta-1-recombinant-protein-96-716.html.

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A61K9/00 (2006.01) G01N 2 7/447 (2006.01) Chusetts 02139 (US)
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