Neolithic and Medieval Virus Genomes Reveal
SHORT REPORT Neolithic and medieval virus genomes reveal complex evolution of hepatitis B Ben Krause-Kyora1,2†*, Julian Susat1†, Felix M Key2, Denise Ku¨ hnert2,3, Esther Bosse1,4, Alexander Immel1,2, Christoph Rinne5, Sabin-Christin Kornell1, Diego Yepes4, So¨ ren Franzenburg1, Henrike O Heyne6,7,8, Thomas Meier9,10, Sandra Lo¨ sch11, Harald Meller12, Susanne Friederich12, Nicole Nicklisch12,13, Kurt W Alt12,13,14,15, Stefan Schreiber1,16, Andreas Tholey4, Alexander Herbig2, Almut Nebel1, Johannes Krause2* 1Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany; 2Max Planck Institute for the Science of Human History, Jena, Germany; 3Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; 4Systematic Proteomics & Bioanalytics, Institute for Experimental Medicine, Kiel University, Kiel, Germany; 5Institute of Pre- and Protohistoric Archaeology, Kiel University, Kiel, Germany; 6Stanley Center for Psychiatric Research, Broad Institute, Cambridge, United States; 7Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, United States; 8Program in Medical and Population Genetics, Broad Institute of MIT & Harvard, Cambridge, United States; 9Institute for Pre- and Protohistory and Near Eastern Archaeology, Heidelberg University, Heidelberg, Germany; 10Heidelberg Center for the Environment, Heidelberg University, Heidelberg, Germany; 11Department of Physical Anthropology, Institute of Forensic Medicine, University of Bern, Bern, Switzerland; 12State Office
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