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Pro-Argin, a Breakthrough Technology Based Upon Arginine American Journal of Dentistry, Vol. 22, Special Issue A, March, 2009 A, March, 22, Special Issue Vol. American Journal of Dentistry, Vol. 22, Special Issue A, March, 2009 - p. 1A - 24A Introducing Pro-Argin™ A Breakthrough Technology Based upon Arginine and Calcium for In-Office Treatment of Dentin Hypersensitivity _______________________________________________________________________________________________________________________________________________________________ Editorial _______________________________________________________________________________________________________________________________________________________________ Dentin hypersensitivity: Beneficial effects of an arginine-calcium carbonate desensitizing paste Dentin hypersensitivity is a common occurrence diately after dental scaling procedures and its and is often a chief concern among patients. The sustained relief over 4 weeks. Another paper pre- pain associated with dentin hypersensitivity is sents the results of a double-blind, stratified, caused by some type of external stimulus and the randomized clinical study showing the successful sensitivity can range in its intensity from patient to desensitizing effect of the 8% arginine-calcium patient. The successful management of dentin carbonate paste tested, when applied as a pre- hypersensitivity is often very challenging for the procedure to professional dental cleaning. dental professional. The cause of the pain and the This Special Issue also includes a study con- description of the discomfort reported by the ducted in vitro, testing the effect of the desensi- patient can vary. tizing paste on the surface roughness of common This Special Issue of the American Journal of dental materials and human enamel. The outcome Dentistry presents the results of studies performed revealed no significant alterations on the surfaces testing an 8% arginine-calcium carbonate desensiti- of the enamel and the materials tested. zing paste, which is based on Pro-ArginTM techno- We hope you will find these papers interesting logy, a combination of arginine and insoluble cal- and educational. The Journal thanks Colgate- cium compound. The Introduction paper is an Palmolive Company, the manufacturer of the overview of dentin hypersensitivity. One paper is a arginine-calcium carbonate desensitizing paste, for double-blind, stratified, randomized clinical study sponsoring this Special Issue. showing the beneficial effects of the 8% arginine- calcium carbonate desensitizing paste used imme- Franklin García-Godoy, DDS, MS Editor ___________________________________________________________________________ The American Journal of Dentistry (ISSN 0894-8275) is published six times a year in the The American Journal of Dentistry invites submission of articles of clinical relevance in months of February, April, June, August, October and December by Mosher & Linder, all fields of dentistry. Information for authors appears on the website: www.Amjdent.com Inc., 318 Indian Trace, #500, Weston, FL 33326-2996, U.S.A. Authors' opinions expressed in the articles are not necessarily those of the American Journal of Dentistry, its Publisher, the Editor or the Editorial Board. 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Editor's address: Dr. Franklin García-Godoy, Editor, American Journal of Dentistry, Subscriptions can begin at any time. Subscribers requiring an address change should College of Dental Medicine, Nova Southeastern University, 3200 S. University Drive, Fort submit an old mailing label with the new address including the zip code, giving 60-day Lauderdale, FL 33328-2018, U.S.A. Address for business matters: 318 Indian Trace notice. #500, Weston, FL 33326-2996, U.S.A. Telephone: (954) 888-9101, Fax: (954) 888-9137. Copyright © 2009 by Mosher & Linder, Inc. All rights reserved. All materials subject to this Claims: Copies not received will be replaced with written notification to the publisher. This copyright and appearing in the American Journal of Dentistry may be photocopied for the notification must be received within 3 months of issue date for U.S.A. subscribers or 4 months noncommercial purpose of scientific or educational advancement. Reproduction of any part for subscribers outside the U.S.A. Claims for issues lost due to insufficient notice of change of of the American Journal of Dentistry for commercial purposes is strictly prohibited unless address will not be honored. Subscribers have no claim if delivery cannot be made due to the publisher's written permission is obtained. events over which the publisher has no control. Orders for subscriptions, remittances and Postmaster: Send change of address or undeliverable copies to the American change of address notices should be sent to the American Journal of Dentistry, Subscription Journal of Dentistry, Subscription Department, 318 Indian Trace #500, Weston, FL Department, 318 Indian Trace, #500, Weston, FL 33326-2996, U.S.A. 33326-2996, U.S.A. Printed in the United States of America. ___________________________________________________________________________ _______________________________________________________________________________________________________________________________________________________________ Special Issue Introduction _______________________________________________________________________________________________________________________________________________________________ Dentin hypersensitivity: Effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate FOTINOS PANAGAKOS, DMD, PHD, THOMAS SCHIFF, DMD & ANNE GUIGNON, RDH, MPH : Dr. Fotinos Panagakos, Director, Professional Relations and Scientific Affairs, Colgate-Palmolive Co., New York, NY, 10022, USA. E- : [email protected] (Am J Dent 2009; 22 Sp Is A:3A-7A) Dentin hypersensitivity is a common occurrence and carrying the stimulus from the tooth surface toward the concern among patients. It is characterized by short, sharp afferent nerve ending in the dentin tubule, resulting in pain.10 pain arising from exposed dentin in response to stimuli, It is, therefore, understandable that the pain caused by this typically thermal, evaporative, tactile, osmotic or chemical, change is transient – once the stimulus is removed or and which cannot be ascribed to any other dental defect or dissipates, the pressure within the tubule returns to normal disease.1,2 The diagnosis of dentin hypersensitivity can be and the pain subsides. very challenging for the dental professional. The cause of the Sensitivity triggers and behavioral considerations pain can vary and the patient’s description of the discomfort may be insufficient to make a definitive diagnosis. The dental Some patients suffer from chronic sensitivity every time professional must perform differential diagnosis to exclude all their teeth are exposed to specific stimuli. Others experience other dental defects and diseases that might give rise to intermittent, unpredictable discomfort that can be difficult to 1,3 similar presentations A thorough examination is essential to pinpoint. One or more stimuli, such as tactile, osmotic help the dental professional make a definitive diagnosis and (sweet), thermal (particularly cold) or evaporative (air move- rule out other possible causes of the pain, such as a split or ment), can initiate a painful response. Certain clinical broken tooth, dental caries or periodontal disease. By activities initiate or heighten dentin hypersensitivity. These correctly diagnosing dentin hypersensitivity, the professional include routine examination with a metal explorer, drying the is able to develop and implement an appropriate treatment tooth with compressed air, hand scaling a root surface and 3,4 plan to address the problem effectively. water temperature changes from the air/water syringe or a Structurally, dentin is composed of hydroxyapatite mineral power scaler. and organic components.5 Formed by the odontoblasts during Patients who have long-standing, unresolved sensitivity tooth development, dentin is uniquely differentiated from other often exhibit a variety of behavioral or postural clues. mineralized tissues in the body because it contains thousands of Behaviors include avoiding needed treatment, insisting on tubules which run perpendicular to the pulp chamber. The anesthesia for simple procedures, reluctance to schedule a tubules are formed as the odontoblasts migrate away from the procedure or a vague concern about discomfort. Postural clues dentin-enamel junction during dentin formation. The tubule include tense facial muscles,
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