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LMBR1 Antibody Cat

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LMBR1 Antibody Cat LMBR1 Antibody Cat. No.: 30-542 LMBR1 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse, Rat Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human LMBR1. TESTED APPLICATIONS: ELISA, WB LMBR1 antibody can be used for detection of LMBR1 by ELISA at 1:1562500. LMBR1 APPLICATIONS: antibody can be used for detection of LMBR1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. POSITIVE CONTROL: 1) Cat. No. 1211 - HepG2 Cell Lysate PREDICTED MOLECULAR 55 kDa WEIGHT: Properties PURIFICATION: Antibody is purified by peptide affinity chromatography method. CLONALITY: Polyclonal CONJUGATE: Unconjugated PHYSICAL STATE: Liquid October 2, 2021 1 https://www.prosci-inc.com/lmbr1-antibody-30-542.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose. CONCENTRATION: batch dependent For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: LMBR1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. Additional Info OFFICIAL SYMBOL: LMBR1 ALTERNATE NAMES: LMBR1, ACHP, C7orf2, DIF14, FLJ11665, PPD2, TPT, ZRS ACCESSION NO.: NP_071903 PROTEIN GI NO.: 21362112 GENE ID: 64327 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References LMBR1 is a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of LMBR1 gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if LMBR1 gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein BACKGROUND: family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis- acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. REFERENCES: 1) Wang, Z.Q., (2007) Biochem. Biophys. Res. Commun. 355 (2), 312-317. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. October 2, 2021 2 https://www.prosci-inc.com/lmbr1-antibody-30-542.html.
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