Monoclonal Antibody to CD102 / ICAM2 - FITC

OriGene Technologies, Inc. OriGene Technologies GmbH

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AM31349FC-N Monoclonal Antibody to CD102 / ICAM2 - FITC

Alternate names: ICAM-2, Intercellular adhesion molecule 2 Quantity: 1ml (100T) Background: ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Uniprot ID: P13598 NCBI: NP_000864 GeneID: 3384 Host / Isotype: Mouse / IgG1 Recommended Isotype SM10F (for use in human samples) Controls: Clone: B-T1 Immunogen: ICAM-2 transfected CHO cells. Remarks: Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells Format: State: Liquid purified IgG fraction Purification: Ion Exchange Chromatography Buffer System: PBS Preservatives: 0.09% Sodium Azide Stabilizers: 5% BSA Label: FITC – Fluorescein Isothiocyanate Isomer 1 Applications: Flow Cytometry: Use 10 µl to label 106 cells in 100 µl of whole blood. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: Recognises the Intercellular Adhesion Molecule-2 (ICAM-2), a 55-65 kDa protein. Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. Shelf life: one year from despatch General Readings: 1. Carreno M-P. et al., J. Virol., 2002; 76 : 32 - 40 2. Dianzani, C. et al.,J. Immunol.,2010;185(7): 3970-3979 3. Kobe et al, AS25 Leukocyte Typing Workshop VI 1996 4. Vermot-Desroches C. et al, AS22.1 Leucocyte Typing Workshop VI 1996

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MS/20160920 1 / 2 AM31349FC-N: Monoclonal Antibody to CD102 / ICAM2 - FITC

Pictures: A typical staining pattern with the B-T1 monoclonal antibody of lymphocytes.

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MS/20160920 2 / 2