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Stem Cell Research, Part 3 Hearings Committee On S. HRG. 106–413 STEM CELL RESEARCH, PART 3 HEARINGS BEFORE A SUBCOMMITTEE OF THE COMMITTEE ON APPROPRIATIONS UNITED STATES SENATE ONE HUNDRED SIXTH CONGRESS SECOND SESSION SPECIAL HEARINGS APRIL 26, 2000—WASHINGTON, DC SEPTEMBER 7, 2000—WASHINGTON, DC SEPTEMBER 14, 2000—WASHINGTON, DC Printed for the use of the Committee on Appropriations ( Available via the World Wide Web: http://www.access.gpo.gov/congress/senate U.S. GOVERNMENT PRINTING OFFICE 66–482 cc WASHINGTON : 2001 For sale by the U.S. Government Printing Office Superintendent of Documents, Congressional Sales Office, Washington, DC 20402 COMMITTEE ON APPROPRIATIONS TED STEVENS, Alaska, Chairman THAD COCHRAN, Mississippi ROBERT C. BYRD, West Virginia ARLEN SPECTER, Pennsylvania DANIEL K. INOUYE, Hawaii PETE V. DOMENICI, New Mexico ERNEST F. HOLLINGS, South Carolina CHRISTOPHER S. BOND, Missouri PATRICK J. LEAHY, Vermont SLADE GORTON, Washington FRANK R. LAUTENBERG, New Jersey MITCH MCCONNELL, Kentucky TOM HARKIN, Iowa CONRAD BURNS, Montana BARBARA A. MIKULSKI, Maryland RICHARD C. SHELBY, Alabama HARRY REID, Nevada JUDD GREGG, New Hampshire HERB KOHL, Wisconsin ROBERT F. BENNETT, Utah PATTY MURRAY, Washington BEN NIGHTHORSE CAMPBELL, Colorado BYRON L. DORGAN, North Dakota LARRY CRAIG, Idaho DIANNE FEINSTEIN, California KAY BAILEY HUTCHISON, Texas RICHARD J. DURBIN, Illinois JON KYL, Arizona STEVEN J. CORTESE, Staff Director LISA SUTHERLAND, Deputy Staff Director JAMES H. ENGLISH, Minority Staff Director SUBCOMMITTEE ON LABOR, HEALTH AND HUMAN SERVICES, AND EDUCATION, AND RELATED AGENCIES ARLEN SPECTER, Pennsylvania, Chairman THAD COCHRAN, Mississippi TOM HARKIN, Iowa SLADE GORTON, Washington ERNEST F. HOLLINGS, South Carolina JUDD GREGG, New Hampshire DANIEL K. INOUYE, Hawaii LARRY CRAIG, Idaho HARRY REID, Nevada KAY BAILEY HUTCHISON, Texas HERB KOHL, Wisconsin TED STEVENS, Alaska PATTY MURRAY, Washington JON KYL, Arizona DIANNE FEINSTEIN, California ROBERT C. BYRD, West Virginia (Ex officio) Professional Staff BETTILOU TAYLOR MARY DIETRICH JIM SOURWINE ELLEN MURRAY (Minority) Administrative Support KEVIN JOHNSON CAROLE GEAGLEY (Minority) (II) CONTENTS WEDNESDAY, APRIL 26, 2000 Page Opening statement of Senator Arlen Specter ........................................................ 1 Statement of Gerald Fischbach, M.D., Director, National Institute of Neuro- logical Disorders and Stroke, National Institutes of Health, Department of Health and Human Services ........................................................................... 2 Prepared statement .......................................................................................... 5 Statement of Allen M. Spiegel, M.D., Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Depart- ment of Health and Human Services ................................................................. 4 Prepared statement .......................................................................................... 5 Opening statement of Senator Tom Harkin .......................................................... 10 Opening statement of Senator Harry Reid ............................................................ 11 Opening statement of Senator Patty Murray ........................................................ 13 Statement of Hon. Sam Brownback, U.S. Senator from Kansas ......................... 15 Prepared statement .......................................................................................... 19 Statement of Frank Young, M.D., Ph.D., Former Commissioner, Food and Drug Administration, Department of Agriculture ............................................. 21 Statement of Mary Jane Owen, M.S.W., executive director, National Catholic Office for Persons With Disabilities ................................................................... 23 Prepared statement .......................................................................................... 26 Statement of Christopher Reeve, actor/director; chairman, Christopher Reeve Paralysis Foundation ........................................................................................... 35 Prepared statement .......................................................................................... 38 Statement of Jennifer Estess, actor/producer ....................................................... 41 Statement of Lawrence B. Goldstein, Ph.D., professor, Division of Cellular and Molecular Medicine, University of California, San Diego School of Med- icine; investigator, Howard Hughes Medical Institute ..................................... 42 Prepared statement .......................................................................................... 45 THURSDAY, SEPTEMBER 7, 2000 Opening statement of Senator Arlen Specter ........................................................ 49 Opening statement of Senator Tom Harkin .......................................................... 51 Statement of Gerald D. Fischbach, M.D., Director, National Institute of Neu- rological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services ........................................................................... 52 Prepared statement .......................................................................................... 55 Statement of Allen M. Spiegel, M.D., Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Depart- ment of Health and Human Services ................................................................. 54 Prepared statement .......................................................................................... 55 Statement of David A. Prentice, M.D., Ph.D., professor of life sciences, Indi- ana State University ............................................................................................ 61 Prepared statement .......................................................................................... 65 Statement of Micheline M. Mathews-Roth, M.D., associate professor of medi- cine, Harvard Medical School .............................................................................. 67 Prepared statement .......................................................................................... 70 THURSDAY, SEPTEMBER 14, 2000 Opening statement of Senator Arlen Specter ........................................................ 81 Statement of Senator Tom Harkin ......................................................................... 82 Statement of Senator Paul D. Wellstone ............................................................... 83 (III) IV Page Statement of Richard O. Hynes, Ph.D, director, Center for Cancer Research, Massachusetts Institute of Technology .............................................................. 83 Prepared statement .......................................................................................... 85 Statement of Darwin J. Prockop, M.D., Ph.D, director, Center for Gene Ther- apy, Tulane University Medical Center ............................................................. 87 Prepared statement .......................................................................................... 89 Statement of Ron Heagy, president and founder of the Life is an Attitude Foundation ............................................................................................................ 93 Statement of Russell Saltzman, pastor, Ruskin Heights Lutheran Church, Kansas City, MO .................................................................................................. 95 Prepared statement .......................................................................................... 96 Statement of Anton-Lewis Usala, M.D., chairman/chief technical officer, Encelle, Inc., Greenville, NC ............................................................................... 98 Prepared statement .......................................................................................... 100 Statement of Gina Gershon, actress ...................................................................... 110 Statement of Jennifer Estess, actor/producer ....................................................... 111 Statement of Mary Tyler Moore, international chairman, Juvenile Diabetes Foundation ............................................................................................................ 113 Prepared statement .......................................................................................... 115 Statement of Michael J. Fox, Foundation for Parkinson’s Research ................... 117 FEDERAL FUNDING FOR STEM CELL RESEARCH WEDNESDAY, APRIL 26, 2000 U.S. SENATE, SUBCOMMITTEE ON LABOR, HEALTH AND HUMAN SERVICES, AND EDUCATION, AND RELATED AGENCIES, COMMITTEE ON APPROPRIATIONS, Washington, DC. The subcommittee met at 11:02 a.m., in room SH–216, Hart Sen- ate Office Building, Hon. Arlen Specter (chairman) presiding. Present: Senators Specter, Harkin, Reid, and Murray. OPENING STATEMENT OF SENATOR ARLEN SPECTER Senator SPECTER. Good morning, ladies and gentlemen. The hearing of the Appropriations Subcommittee on Labor, Health and Human Services, and Education will now proceed. We are taking up a very important subject today, and that is the issue of Federal funding for stem cell research. This is the fifth hearing which the subcommittee is holding on this very important subject, and we do it as a preliminary to action on the Senate floor on this subject, which will be taken up in the course
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