Available online at http://www.ifgdg.org Int. J. Biol. Chem. Sci. 14(2): 613-625, February 2020 ISSN 1997-342X (Online), ISSN 1991-8631 (Print) Original Paper http://ajol.info/index.php/ijbcs http://indexmedicus.afro.who.int Mycotoxin contamination of herbal medications on sale in Ebonyi State, Nigeria Richard C. IKEAGWULONU1*, Charles C. ONYENEKWE1, Nkiruka R. UKIBE1, Charles G. IKIMI2, Friday A. EHIAGHE1, Isaac P. EMEJE1 and Solomon N. UKIBE3 1Department of Medical Laboratory Science, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, P. M. B 5025, Anambra State, Nigeria. 2Department of Biochemistry, Faculty of Science, Federal University of Otuoke, Beyalsa State, Nigeria. 3Department of Microbiology, Faculty of Medicine, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi Campus, P. M. B 5025, Anambra State, Nigeria. *Corresponding author; E-mail:
[email protected]. Tel: +23407080013228. ABSTRACT The practice of herbal medication is as old as the culture of the people and despite the advent of modern medication, many people of south eastern Nigeria, still patronizes herbal medication. Herbal medications are consumed directly and could be contaminated with mycotoxins which are detrimental to human and animal health. This study was therefore, designed to determine the extent of mycotoxin contamination of herbal medications on sale in Ebonyi State, South-Eastern Nigeria. In this regard, a multistage random sampling technique was used to select 19 herbal medication samples from stores and markets in Ebonyi State, Nigeria and evaluated for occurrence of three major mycotoxins- aflatoxins (AFs), ochratoxin A (OTA) and fumonisins (FB). Employing wet extraction procedure, mycotoxin occurrence and levels were determined via lateral flow immunoassay technique.