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CSIR-IICB CSIR-Indian Institute of Chemical Biology Annual Report 2016-17 #$%&' ! " ! #$%&' ( ! " ! #$%&' ( Courtesy : Dr. Suvendra Nath Bhattacharya Annual Report 2016-17 Jadavpur Campus Salt Lake Campus CSIR-Indian Institute of Chemical Biology 4, Raja S. C. Mullik Road, Jadavpur, Kolkata - 700 032, India Cancer Biology & Project Monitoring Inflammatory Disorder & Evaluation Infectious Diseases Art & & Immunology Photography Cell Biology Business & Physiology Development Group Molecular Genetics ISTAD Organic & Medicinal Chemistry IPM Cell Structural Biology & Bio-informatics P&I R & D P&I - PME & BDG Divisions Division Animal House Electrical Engineering Library & Documentation Maintenance CSIR Electrical Instrumentation IICB Central Architecture Facilities & Civil Engineering Kolkata Infrastructure Computer Maintenance (Civil) Human Resource Group Administration Director’s Finance & Secretariate Accounts General Stores & Administration Purchase Establishment Bill General Section Store R & C Cash Foreign Section Section Purchase Security & Receipts & Indigenous Maintenance Despatch Purchase Works & Hindi Cell Services Contents Director’s Report 005 Cell Biology & Physiology Division 009 Infectious Diseases & Immunology Division 027 Cancer Biology & Inflammatory Disorders Division 037 Organic & Medicinal Chemistry Division 059 Molecular Genetics Division 079 Structural Biology & Bioinformatics Division 085 Network Projects in 12th Five year Plan (2012-17) 105 Publication & Information and Planning, Monitoring & Evaluation Division 113 Performance at a Glance 135 Central Facilities 144 Engineering Services Unit (ESU) 153 Administration 155 Publication Highlights 157 Doctorates From CSIR-IICB 171 Staff List of CSIR-IICB as on March 31, 2017 173 DirectorDirector’s’s Report It is my proud privilege to present the Annual Report which assembles the major activities of this Institute for the period from April 2016 to March 2017. This report is an indication of our growth and a document of our accountability. Every year the Institute publishes its Annual Report to disseminate a brief description of our research activities to our friends, well wishers and scientific communities across the globe. Apart from the scientific contributions, this report also includes significant information about our infrastructure, extramural funding, publication, intellectual property and other various aspects of scientific management and administration. The institute embodies a symbiosis between chemistry and biology that translates to a commitment to advance affordable healthcare for all. While biologists are constantly working on comprehending physiological processes and diseases, chemists are tirelessly making tools to harness and redefine biological phenomena. The progress of CSIR-IICB essentially depends on its R&D activities and like preceding years the institute continued its growth through quality research on diseases of national importance and biological problems of global interest, employing sophisticated state-of-the-art technology in keeping with the rapid and unprecedented momentum that life science research has gained globally over the last five decades. CSIR- IICB Infrastructure continues to be upgraded. In order to strengthen the basic research and to attain translational objectives, a second campus with a four storey building was constructed at Salt Lake, Kolkata which is operational. The unit is named CSIR-IICB Translational Research Unit of Excellence (TRUE). This new unit has objective for research facilitation by establishing advanced technological platforms, establishing a Biomedical Incubation Center for MSMEs, start- up companies and translating discoveries made by CSIR-IICB 005 scientists. The overall direction is towards translation of the IICB was assigned with nineteen (19) Planned Projects of state-of-the-art fundamental and indigenous innovations to CSIR in the Twelfth Five Year Plan of which five (5) are Nodal affordable technology for societal benefits of the common Network Projects and fourteen (14) are Partner Network man. The role of CSIR-IICB in ‘Affordable healthcare through Projects and the idea and initiation of these projects have modern science’ is well recognized since its early days. We been highly appreciated by the Research Council (RC) of this have offered substantial attention in developing drug from our Institute. These projects networked with other CSIR labs, will indigenous and natural resources like native Indian plants. I exploit the potential of CSIR-IICB scientists. am indeed happy to note that the stride for progress has continued unabated towards excellence and in the last few On 2nd April, 2016 CSIR-IICB organized its 60th Foundation years we have taken major steps to translate its research Day celebration. Prof. Santanu Bhattacharya, Director, Indian results into products for societal benefit. The institute is doing Association for the Cultivation of Science, Kolkata was present well in terms of technology transfer. Drugs like 'Asmon' and as Guest-in-Chief and Dr. R. A. Vishwakarma, Director, CSIR- 'Prostalyn' developed by us from Indian medicinal plants are IIIM, Jammu delivered the 28th J.C. Ray Memorial Lecture. marketed. The Institute observed Hindi Week during 7th-14th September, CSIR-IICB now holds six major scientific divisions: Cell Biology 2016 by organizing different competitions like debate in Hindi, & Physiology, Infectious Diseases & Immunology, Cancer noting & drafting competitions and a workshop was conducted Biology & Inflammatory Disorder, Organic & Medicinal on Unicode. The Institute also celebrated National Hindi Day Chemistry, Molecular Genetics and Structural Biology & on 14th September, 2016 and the Hindi patrika, Sanjeevani Bioinformatics. Scientists are continuing their efforts to unravel 2015-2016 was released on that day. The chief guest of the the molecular basis of cancer, altered immune responses day was Prof. Jagdishwar Chaturvedi, Calcutta University and during chronic infection and inflammation, and the the Guest of Honor was Dr. Geeta Dubey, Scottish Church pathophysiology of several metabolic and neurodegenerative College, Kolkata. disorders such as Diabetes and Alzheimer’s disease. CSIR- IICB is one of the major institutes in India which initiated, right The Institute observed the 75th Foundation Day of CSIR on from its inception, multi-disciplinary concerted efforts for September 28, 2016 at Dr. J. C. Ray Memorial Auditorium of conducting basic research on infectious diseases, specifically the institute. Prof. Anuradha Lohia, Vice Chancellor, Presidency leishmaniasis and cholera, along with the development of University, graced the occasion as Guest-in- Chief and Prof. technologies for the diagnosis, immunoprophylaxis and Shekhar C. Mande, Director, National Centre for Cell Science, chemotherapy of the diseases. Pune, delivered the Foundation Day invitation Lecture on “Mapping Protein Flexibility”. During the reporting period thirty two (32) extramural projects from different funding agencies are continued by different CSIR-IICB organized a number of national and international scientists of the institute, which include international projects level seminars and symposiums during this reporting period. also. Several new projects have been sanctioned. Based on On 3rd June, 2016 CSIR-IICB organized 2nd B.K. Bachhawat the expertise available through scientific endeavour, CSIR- Memorial Lecture and Symposium on Chemical Biology 006 Research at the J.C. Ray Auditorium of CSIR-IICB, Jadavpur Academy of Sciences, Bengaluru, National Bioscience Award, Campus. An Indo-Brazil Symposium on Biochemistry of Fellowship of the Royal Society of Chemistry (FRSC), UK, Kinetoplastid Parasites was organized by the institute during Senior Scientist Platinum Jubilee Fellowship from The National September 19-20, 2016. The main purpose of the symposium Academy of Sciences, India (NASI) and Young Scientist Award was to have an in-depth discussion on different aspects of from Indian Peptide Society are important. Leishmania and Trypanosoma researches being carried out A large number of scientists and technologists of national and in two countries. Twenty five speakers delivered lectures on international repute visited our institute, delivered lectures and two different parasites in these two days symposium. On held discussions with different research groups in CSIR-IICB September 27, 2016 Indian Association of Cancer Research during this reporting year. Among which a lecture on "Regulation (IACR), WB Chapter in association with CSIR-IICB organized a seminar in this institute. There were lectures on recent of Cell Cycle and Replication in Cancer Cells" by advances on clinical and basic research on Cancer followed Dr. Samarendra K Singh, University of Virginia, Charlottesville, by a short panel discussion. At the end a 'very special' cultural Virginia, USA., visit of Dr Prabuddha Mukherjee, University of program was presented by the little kids of Thakurpukur Cancer Illinois at Urbana Champaign USA for scientific lecture on Hospital. India International Science Festival (IISF) Curtain “Multimodal Imaging in Biological Systems”, visit of Dr. Partha Raiser, Outreach Programme was organized by CSIR-IICB Sarkar, UTMB , Galveston, Texas USA for a lecture on "CAG on November 23, 2016 and 3rd International Meet on Advanced repeat expansion: the mechanism of neuronal dysfunction Studies in Cell Signaling Network ( CeSiN-2016)
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