Supplement to National Bureau of Standards Circular No. 562
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Transport of Dangerous Goods
ST/SG/AC.10/1/Rev.16 (Vol.I) Recommendations on the TRANSPORT OF DANGEROUS GOODS Model Regulations Volume I Sixteenth revised edition UNITED NATIONS New York and Geneva, 2009 NOTE The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. ST/SG/AC.10/1/Rev.16 (Vol.I) Copyright © United Nations, 2009 All rights reserved. No part of this publication may, for sales purposes, be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, magnetic tape, mechanical, photocopying or otherwise, without prior permission in writing from the United Nations. UNITED NATIONS Sales No. E.09.VIII.2 ISBN 978-92-1-139136-7 (complete set of two volumes) ISSN 1014-5753 Volumes I and II not to be sold separately FOREWORD The Recommendations on the Transport of Dangerous Goods are addressed to governments and to the international organizations concerned with safety in the transport of dangerous goods. The first version, prepared by the United Nations Economic and Social Council's Committee of Experts on the Transport of Dangerous Goods, was published in 1956 (ST/ECA/43-E/CN.2/170). In response to developments in technology and the changing needs of users, they have been regularly amended and updated at succeeding sessions of the Committee of Experts pursuant to Resolution 645 G (XXIII) of 26 April 1957 of the Economic and Social Council and subsequent resolutions. -
Effects of Heavy Water (D2O) on Human Pancreatic Tumor Cells
ANTICANCER RESEARCH 25: 3407-3412 (2005) Effects of Heavy Water (D2O) on Human Pancreatic Tumor Cells JOHANNES HARTMANN1, YVONNE BADER1, ZSUZSANNA HORVATH1, PHILIPP SAIKO1, MICHAEL GRUSCH1, CHRISTOPH ILLMER1, SIBYLLE MADLENER1, MONIKA FRITZER-SZEKERES1, NICOLE HELLER2, RUDOLF-GIESBERT ALKEN2 and THOMAS SZEKERES1 1Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria; 2BDD Berolina Drug Development GmbH, Fontanestrasse 84-89, D-15366 Neuenhagen, Germany Abstract. Background: Pancreatic cancer constitutes an carcinomas be removed by surgery. Individuals suffering entity which is difficult to treat and, therefore, mostly fatal. from inoperable tumors receive palliative therapy, including Since heavy water (deuterium oxide, D2O) was shown to be chemotherapy and radiation therapy. However, the active in various cancer cell lines in vitro and in vivo, we now treatment options are very limited and most patients die investigated its effects in human pancreatic tumor cells. within months after diagnosis. Materials and Methods: The cytotoxic effects of D2O were Incubation of tumor cells with various concentrations of examined in three pancreatic cancer cell lines (AsPC-1, D2O leads to inhibition of cell proliferation and might, BxPC-3 and PANC-1). Induction of apoptosis was therefore, help in the chemotherapeutic treatment of human determined by Hoechst/propidium iodide double staining and tumors (1). D2O, known as heavy water, contains a neutron cell cycle distribution was investigated by FACS analysis. and a proton in its hydrogen atoms and shows a variety of Results: Employing a clonogenic assay, D2O yielded IC50 different biological activities from normal (light) water. -
Deuterium As a Research Tool in the Physical and Biological Sciences
DEUTERIUM AS A RESEARCH TOOL IN THE PHYSICAL AND BIOLOGICAL SCIENCES HERRICK L. JOHNSTON Ohio State University The discovery (1) of deuterium and the production of "heavy water," its chief compound, in a nearly pure state (2), are among the more important scientific achievements of recent years. In less than two years from the production of heavy water in nearly pure condition over three hundred papers reporting investigations on or with deuterium have appeared in scientific journals. While most of these investiga- tions have been of a physical or chemical nature significant results have been reported in investigations of biological character. It is probable that the principal role of deuterium, in future research in all of these fields, will be more that of a research tool than as an object of investigation. Deuterium is not a new chemical element, as the name might imply, but is a special variety of hydrogen atom. It differs from the ordinary (or light) hydrogen, chiefly, in mass. The atomic weight of the ordinary hydrogen is one while that of deuterium, or heavy hydrogen, is two. It resembles the ordinary hydrogen atom in possessing just one unit of positive charge on its nucleus (equal to the number of electrons in the neutral atom) and it is this latter property which determines the chemical character of an atom, and hence its position in the family of elements. The existence of atoms which differ in mass although alike in nuclear charge is common among the elements, and atomic species which are related in this manner are called isotopes. -
Germane Facts About Germanium Sesquioxide: I. Chemistry and Anticancer Properties
THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE Volume 10, Number 2, 2004, pp. 337–344 ©Mary Ann Liebert, Inc. Germane Facts About Germanium Sesquioxide: I. Chemistry and Anticancer Properties BONNIEJ. KAPLAN, Ph.D., 1 W. WESLEYPARISH, Ph.D., 2 G. MERRILLANDRUS, Ph.D., 2 J. STEVENA. SIMPSON, Ph.D., M.D., 3 and CATHERINEJ. FIELD, Ph.D., R.D. 4 ABSTRACT This paper reviews the history, chemistry, safety, toxicity, and anticancer effects of the organogermanium compound bis (2-carboxyethylgermanium) sesquioxide (CEGS). A companion review follows, discussing the inaccuracies in the scientific record that have prematurely terminated research on clinical uses of CEGS. CEGS is a unique organogermanium compound first made by Mironov and coworkers in Russia and, shortly there- after, popularized by Asai and his colleagues in Japan. Low concentrations of germanium occur in nearly all soils, plants and animal life; natural occurrence of the CEGS form is postulated but not yet demonstrated. The literature demonstrating its anticancer effect is particularly strong: CEGS induces interferon- g (IFN-g), en- hances natural killer cell activity, and inhibits tumor and metastatic growth—effects often detectable after a single oral dose. In addition, oral consumption of CEGS is readily assimilated and rapidly cleared from the body without evidence of toxicity. Given these findings, the absence of human clinical trials of CEGS is un- expected. Possible explanations of why the convincing findings from animal research have not been used to support clinical trials are discussed. Clinical trials on CEGS are recommended. INTRODUCTION bispropionic acid; 3-oxygermylpropionic acid polymer; poly- trans-(2-carboxyethyl) germasesquioxane); proxigerma- n general, dietary supplements are an underinvestigated nium; repagermanium; and Serocion. -
A Photoionization Reflectron Time‐Of‐Flight Mass Spectrometric
Articles ChemPhysChem doi.org/10.1002/cphc.202100064 A Photoionization Reflectron Time-of-Flight Mass Spectrometric Study on the Detection of Ethynamine (HCCNH2) and 2H-Azirine (c-H2CCHN) Andrew M. Turner,[a, b] Sankhabrata Chandra,[a, b] Ryan C. Fortenberry,*[c] and Ralf I. Kaiser*[a, b] Ices of acetylene (C2H2) and ammonia (NH3) were irradiated with 9.80 eV, and 10.49 eV were utilized to discriminate isomers energetic electrons to simulate interstellar ices processed by based on their known ionization energies. Results indicate the galactic cosmic rays in order to investigate the formation of formation of ethynamine (HCCNH2) and 2H-azirine (c-H2CCHN) C2H3N isomers. Supported by quantum chemical calculations, in the irradiated C2H2:NH3 ices, and the energetics of their experiments detected product molecules as they sublime from formation mechanisms are discussed. These findings suggest the ices using photoionization reflectron time-of-flight mass that these two isomers can form in interstellar ices and, upon spectrometry (PI-ReTOF-MS). Isotopically-labeled ices confirmed sublimation during the hot core phase, could be detected using the C2H3N assignments while photon energies of 8.81 eV, radio astronomy. 1. Introduction acetonitrile (CH3CN; 1) and methyl isocyanide (CH3NC; 2) ‘isomer doublet’ (Figure 2) – the methyl-substituted counterparts of For the last decade, the elucidation of the fundamental reaction hydrogen cyanide (HCN) and hydrogen isocyanide (HNC) – has pathways leading to structural isomers – molecules with the been detected toward the star-forming region SgrB2.[4,8–9] same molecular formula, but distinct connectivities of atoms – However, none of their higher energy isomers has ever been of complex organic molecules (COMs) in the interstellar identified in any astronomical environment: 2H-azirine (c- [10–14] [15–19] medium (ISM) has received considerable interest from the NCHCH2; 3), ethynamine (HCCNH2; 4), ketenimine [1–3] [20] [21] astrochemistry and physical chemistry communities. -
S-Block Amidoboranes: Syntheses, Structures, Reactivity and Applications Cite This: Chem
Chem Soc Rev View Article Online REVIEW ARTICLE View Journal | View Issue s-Block amidoboranes: syntheses, structures, reactivity and applications Cite this: Chem. Soc. Rev., 2016, 45, 1112 Tom E. Stennett and Sjoerd Harder* Metal amidoborane compounds of the alkali- and alkaline earth metals have in recent years found applications in diverse disciplines, notably as hydrogen storage materials, as reagents for the reduction of organic functional groups and as catalysts and intermediates in dehydrocoupling reactions. These functions are connected by the organometallic chemistry of the MNR2BH3 group.† This review focusses on central aspects of the s-block amidoborane compounds – their syntheses, structures and reactivity. Well-defined amidoborane complexes of group 2 metals are now available by a variety of solution-phase routes, which has allowed a more detailed analysis of this functional group, which was previously largely confined to solid-state materials chemistry. Structures obtained from X-ray crystallography have begun to provide increased understanding of the fundamental steps of key processes, including amine–borane Creative Commons Attribution 3.0 Unported Licence. dehydrocoupling and hydrogen release from primary and secondary amidoboranes. We review structural parameters and reactivity to rationalise the effects of the metal, nitrogen substituents and supporting Received 10th July 2015 ligands on catalytic performance and dehydrogenative decomposition routes. Mechanistic features of DOI: 10.1039/c5cs00544b key processes involving amidoborane compounds as starting materials or intermediates are discussed, alongside emerging applications such as the use of group 1 metal amidoboranes in synthesis. Finally, the www.rsc.org/chemsocrev future prospects of this vibrant branch of main group chemistry are evaluated. -
WTR-Core Product Code SMI2337-1 SDS No
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU) 2015/830 SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier Product name WTR-Core Product code SMI2337-1 SDS no. SMI2337-1 Product type Paste 1.2 Relevant identified uses of the substance or mixture and uses advised against Use of the substance/ Analytical reagent that is mixed with activator to form a test kit. mixture For specific application advice see appropriate Technical Data Sheet or consult our company representative. 1.3 Details of the supplier of the safety data sheet Supplier BP Marine Limited Chertsey Road Sunbury-on-Thames Middlesex TW16 7LN United Kingdom E-mail address [email protected] 1.4 Emergency telephone number EMERGENCY Carechem: +44 (0) 1235 239 670 (24/7) TELEPHONE NUMBER SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Product definition Mixture Classification according to Regulation (EC) No. 1272/2008 [CLP/GHS] Not classified. Ingredients of unknown Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 1% toxicity Percentage of the mixture consisting of ingredient(s) of unknown acute dermal toxicity: 1% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 1% Ingredients of unknown Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic ecotoxicity environment: 1% See sections 11 and 12 for more detailed information on health effects and symptoms and environmental hazards. 2.2 Label elements Signal word No signal word. -
Risto Laitinen/August 4, 2016 International Union of Pure and Applied Chemistry Division VIII Chemical Nomenclature and Structur
Approved Minutes, Busan 2015 Risto Laitinen/August 4, 2016 International Union of Pure and Applied Chemistry Division VIII Chemical Nomenclature and Structure Representation Approved Minutes of Division Committee Meeting in Busan, Korea, 8–9 August, 2015 1. Welcome, introductory remarks and housekeeping announcements Karl-Heinz Hellwich (KHH) welcomed everybody to the meeting, extending a special welcome to those who were attending the Division Committee meeting for the first time. He described house rules and arrangements during the meeting. KHH also regretfully reported that it has come to his attention that since the Bangor meeting in August 2014, Prof. Derek Horton (Member, Division VIII task groups on Carbohydrate and Flavonoids nomenclature; Associate Member, IUBMB-IUPAC Joint Commission on Biochemical Nomenclature) and Dr. Libuse Goebels, Member of the former Commission on Nomenclature of Organic Chemistry) have passed away. The meeting attendees paid a tribute to their memory by a moment of silence. 2. Attendance and apologies Present: Karl-Heinz Hellwich (president, KHH) , Risto Laitinen (acting secretary, RSL), Richard Hartshorn (past-president, RMH), Michael Beckett (MAB), Alan Hutton (ATH), Gerry P. Moss (GPM), Michelle Rogers (MMR), Jiří Vohlídal (JV), Andrey Yerin (AY) Observers: Leah McEwen (part time, chair of proposed project, LME), Elisabeth Mansfield (task group chair, EM), Johan Scheers (young observer, day 1; JS), Prof. Kazuyuki Tatsumi (past- president of the union, part of day 2) Apologies: Ture Damhus (secretary, TD), Vefa Ahsen, Kirill Degtyarenko, Gernot Eller, Mohammed Abul Hashem, Phil Hodge (PH), Todd Lowary, József Nagy, Ebbe Nordlander (EN), Amélia Pilar Rauter (APR), Hinnerk Rey (HR), John Todd, Lidija Varga-Defterdarović. -
Calcium Hydride, Grade S
TECHNICAL DATA SHEET Date of Issue: 2016/09/02 Calcium Hydride, Grade S CAS-No. 7789-78-8 EC-No. 232-189-2 Molecular Formula CaH₂ Product Number 455150 APPLICATION Calcium hydride is used primarily as a source of hydrogen, as a drying agent for liquids and gases, and as a reducing agent for metal oxides. SPECIFICATION Ca total min. 92 % H min. 980 ml/g CaH2 Mg max. 0.8 % N max. 0.2 % Al max. 0.01 % Cl max. 0.5 % Fe max. 0.01 % METHOD OF ANALYSIS Calcium complexometric, impurities by spectral analysis and special analytical procedures. Gas volumetric determination of hydrogen. Produces with water approx. 1,010 ml hydrogen per gram. PHYSICAL PROPERTIES Appearance powder Color gray white The information presented herein is believed to be accurate and reliable, but is presented without guarantee or responsibility on the part of Albemarle Corporation and its subsidiaries and affiliates. It is the responsibility of the user to comply with all applicable laws and regulations and to provide for a safe workplace. The user should consider any health or safety hazards or information contained herein only as a guide, and should take those precautions which are necessary or prudent to instruct employees and to develop work practice procedures in order to promote a safe work environment. Further, nothing contained herein shall be taken as an inducement or recommendation to manufacture or use any of the herein materials or processes in violation of existing or future patent. Technical data sheets may change frequently. You can download the latest version from our website www.albemarle-lithium.com. -
Germane 99.99+%
GEG5001 - GERMANE 99.99+% GERMANE 99.99+% Safety Data Sheet GEG5001 Date of issue: 01/05/2015 Version: 1.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form : Substance Physical state : Gas Substance name : GERMANE 99.99+% Product code : GEG5001 Formula : GeH4 Synonyms : MONOGERMANE; GERMANIUM HYDRIDE; GERMANIUM TETRAHYDRIDE Chemical family : GERMANE 1.2. Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture : Chemical intermediate For research and industrial use only 1.3. Details of the supplier of the safety data sheet GELEST, INC. 11 East Steel Road Morrisville, PA 19067 USA T 215-547-1015 - F 215-547-2484 - (M-F): 8:00 AM - 5:30 PM EST [email protected] - www.gelest.com 1.4. Emergency telephone number Emergency number : CHEMTREC: 1-800-424-9300 (USA); +1 703-527-3887 (International) SECTION 2: Hazards identification 2.1. Classification of the substance or mixture Classification (GHS-US) Flam. Gas 1 H220 Liquefied gas H280 Acute Tox. 2 (Inhalation:gas) H330 Eye Irrit. 2A H319 STOT SE 3 H335 Full text of H-phrases: see section 16 2.2. Label elements GHS-US labeling Hazard pictograms (GHS-US) : GHS02 GHS04 GHS06 GHS07 Signal word (GHS-US) : Danger Hazard statements (GHS-US) : H220 - Extremely flammable gas H280 - Contains gas under pressure; may explode if heated H319 - Causes serious eye irritation H330 - Fatal if inhaled H335 - May cause respiratory irritation Precautionary statements (GHS-US) : P284 - [In case of inadequate ventilation] wear respiratory protection P280 - Wear protective gloves/protective clothing/eye protection/face protection P260 - Do not breathe gas P264 - Wash hands thoroughly after handling P310 - Immediately call a doctor P210 - Keep away from heat, open flames, sparks. -
Flexible Solar Cells
Flexible Solar Cells A Major Qualifying Project Submitted to the Faculty Of Worcester Polytechnic Institute In Partial Fulfillment of the requirements for the Degree in Bachelor of Science In Mechanical Engineering By Francis LaRovere Edward Peglow Michael McMahon Project Advisor Professor Pratap Rao, Advisor This report represents work of WPI undergraduate students submitted to the faculty as evidence of a degree requirement. WPI routinely publishes these reports on its w ebsite without editorial or peer review. For more information about the projects program at WPI, see http://www.wpi.edu/Academics/Projects. 1 Table of Contents Table of Figures ............................................................................................................................................. 5 Table of Tables .............................................................................................................................................. 6 Acknowledgments ......................................................................................................................................... 7 Abstract ......................................................................................................................................................... 8 1. Introduction .............................................................................................................................................. 9 2. Scope ...................................................................................................................................................... -
Safety Data Sheet Material Name: SILANE SDS ID: MAT20590
Safety Data Sheet Material Name: SILANE SDS ID: MAT20590 * * * Section 1 - PRODUCT AND COMPANY IDENTIFICATION * * * Manufacturer Information MATHESON TRI-GAS, INC. General Information: 1-800-416-2505 150 Allen Road, Suite 302 Emergency #: 1-800-424-9300 (CHEMTREC) Basking Ridge, NJ 07920 Outside the US: 703-527-3887 (Call collect) Chemical Family hydrides Synonyms MTG MSDS 78; MONOSILANE (SIH4); SILICANE; SILICON HYDRIDE (SIH4); SILICON TETRAHYDRIDE; SILICON HYDRIDE; MONOSILANE; STCC 4920168; UN 2203; H4Si; RTECS: VV1400000 Product Use industrial Usage Restrictions None known. * * * Section 2 - HAZARDS IDENTIFICATION * * * EMERGENCY OVERVIEW Color: colorless Physical Form: gas Odor: unpleasant odor Health Hazards: respiratory tract irritation, skin irritation, eye irritation Physical Hazards: May explode on contact with water. Flammable gas. May cause flash fire. Extremely flammable. May ignite spontaneously on exposure to air. ____________________________________________________________ Page 1 of 10 Issue Date: 03/17/2010 Revision: 1.0201 Print Date: 6/15/2010 Safety Data Sheet Material Name: SILANE SDS ID: MAT20590 POTENTIAL HEALTH EFFECTS Inhalation Short Term: irritation, nausea, headache Long Term: lung damage Skin Short Term: irritation, blisters Long Term: same as effects reported in short term exposure Eye Short Term: irritation, blurred vision Long Term: same as effects reported in short term exposure Ingestion Short Term: frostbite Long Term: no information is available * * * Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS * * * CAS Component Percent 7803-62-5 SILANE 100.0 * * * Section 4 - FIRST AID MEASURES * * * Inhalation If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not breathing. Get immediate medical attention. Skin If frostbite or freezing occur, immediately flush with plenty of lukewarm water (105 -115 F; 41-46 C).