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Rabbit Anti-Golgin 97/FITC Conjugated antibody

SL13486R-FITC

Product Name: Anti-Golgin 97/FITC Chinese Name: FITC标记的高尔基体蛋白97抗体 Gap junction protein alpha 4 37kD; GOGA1_HUMAN; Golga 1; Golga1; Golgi autoantigen golgin subfamily a 1; Golgi autoantigen golgin subfamily A member 1; Alias: Golgi autoantigen golgin subfamily a1.; Golgin A1; Golgin subfamily A member 1; Golgin-97; Golgin97; MGC33154. Organism Species: Rabbit Clonality: Polyclonal React Species: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 88kDa Cellular localization: The cell membrane Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human Golgin 9 Lsotype: IgGwww.sunlongbiotech.com Purification: affinity purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: The GRIP family member, golgin 97, is a trans-Golgi network peripheral membrane protein with an extensive coiled-coil structure (67% alpha-helical content) and a C- Product Detail: terminal GRIP domain. Golgin 97 localizes exclusively on the cytoplasmic face of the Golgi and can form homodimers. Binding of golgin 97 to the Golgi membrane is mediated by the G protein family member, Arl1. Golgin 97 acts as an essential player to the cell in the form of a tethering molecule associating with tubulovesicular carriers during the trafficking from the trans-Golgi network to the recycling endosome and/or early endosome. During poxvirus infection, golgin 97 accumulates at the site of viral replication and is incorporated into virions. It associates with the insoluble fraction of the virus core protein, playing a significant role in virus replication and maturation of the virus membrane and core protein. Golgin 97 takes on a rod-like shape and, although it seemingly lacks a transmembrane domain, it protrudes from the surface of the virion envelope.

Function: Probably involved in maintaining Golgi structure.

Subunit: Binds RAB6A.

Subcellular Location: Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.

Similarity: Contains 1 GRIP domain.

Database links:

Entrez Gene: 2800Human

Entrez Gene: 76899Mouse

Entrez Gene: 311919Rat

Omim: 602502Human

SwissProt: Q92805Human

SwissProt: Q9CW79Mouse Unigene:www.sunlongbiotech.com 133469Human Unigene: 59504Human

Unigene: 131098Mouse

Unigene: 206017Rat

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.