Qt8wf5x99q Nosplash 9C93dda
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Developing a Better Breeding Program
Pedigree Analysis and How Breeding Decisions Affect Genes Jerold S Bell DVM, Clinical Associate Professor of Genetics, Tufts Cummings School of Veterinary Medicine To some breeders, determining which traits will appear in may be phenotypically uniform, but will rarely breed true due the offspring of a mating is like rolling the dice - a to the mix of dissimilar genes. combination of luck and chance. For others, producing certain traits involves more skill than luck - the result of One reason to outbreed would be to bring in new traits that careful study and planning. As breeders, you must your breeding stock does not possess. While the parents may understand how matings manipulate genes within your be genetically dissimilar, you should choose a mate that breeding stock to produce the kinds of offspring you desire. corrects your breeding animal's faults but complements its good traits. It is not unusual to produce an excellent quality When evaluating your breeding program, remember that individual from an outbred litter. The abundance of genetic most traits you're seeking cannot be changed, fixed or variability can place all the right pieces in one individual. created in a single generation. The more information you Many top-winning show animals are outbred. Consequently, can obtain on how certain traits have been transmitted by however, they may have low inbreeding coefficients and may your animal's ancestors, the better you can prioritize your lack the ability to uniformly pass on their good traits to their breeding goals. Tens of thousands of genes interact to offspring. After an outbreeding, breeders may want to breed produce a single individual. -
February 26, 2021 Amazon Warehouse Workers In
February 26, 2021 Amazon warehouse workers in Bessemer, Alabama are voting to form a union with the Retail, Wholesale and Department Store Union (RWDSU). We are the writers of feature films and television series. All of our work is done under union contracts whether it appears on Amazon Prime, a different streaming service, or a television network. Unions protect workers with essential rights and benefits. Most importantly, a union gives employees a seat at the table to negotiate fair pay, scheduling and more workplace policies. Deadline Amazon accepts unions for entertainment workers, and we believe warehouse workers deserve the same respect in the workplace. We strongly urge all Amazon warehouse workers in Bessemer to VOTE UNION YES. In solidarity and support, Megan Abbott (DARE ME) Chris Abbott (LITTLE HOUSE ON THE PRAIRIE; CAGNEY AND LACEY; MAGNUM, PI; HIGH SIERRA SEARCH AND RESCUE; DR. QUINN, MEDICINE WOMAN; LEGACY; DIAGNOSIS, MURDER; BOLD AND THE BEAUTIFUL; YOUNG AND THE RESTLESS) Melanie Abdoun (BLACK MOVIE AWARDS; BET ABFF HONORS) John Aboud (HOME ECONOMICS; CLOSE ENOUGH; A FUTILE AND STUPID GESTURE; CHILDRENS HOSPITAL; PENGUINS OF MADAGASCAR; LEVERAGE) Jay Abramowitz (FULL HOUSE; GROWING PAINS; THE HOGAN FAMILY; THE PARKERS) David Abramowitz (HIGHLANDER; MACGYVER; CAGNEY AND LACEY; BUCK JAMES; JAKE AND THE FAT MAN; SPENSER FOR HIRE) Gayle Abrams (FRASIER; GILMORE GIRLS) 1 of 72 Jessica Abrams (WATCH OVER ME; PROFILER; KNOCKING ON DOORS) Kristen Acimovic (THE OPPOSITION WITH JORDAN KLEPPER) Nick Adams (NEW GIRL; BOJACK HORSEMAN; -
Clones Stick Together
TVhome The Daily Home April 12 - 18, 2015 Clones Stick Together Sarah (Tatiana Maslany) is on a mission to find the 000208858R1 truth about the clones on season three of “Orphan Black,” premiering Saturday at 8 p.m. on BBC America. The Future of Banking? We’ve Got A 167 Year Head Start. You can now deposit checks directly from your smartphone by using FNB’s Mobile App for iPhones and Android devices. No more hurrying to the bank; handle your deposits from virtually anywhere with the Mobile Remote Deposit option available in our Mobile App today. (256) 362-2334 | www.fnbtalladega.com Some products or services have a fee or require enrollment and approval. Some restrictions may apply. Please visit your nearest branch for details. 000209980r1 2 THE DAILY HOME / TV HOME Sun., April 12, 2015 — Sat., April 18, 2015 DISH AT&T DIRECTV CABLE CHARTER CHARTER PELL CITY PELL ANNISTON CABLE ONE CABLE TALLADEGA SYLACAUGA BIRMINGHAM BIRMINGHAM BIRMINGHAM CONVERSION CABLE COOSA SPORTS WBRC 6 6 7 7 6 6 6 6 AUTO RACING Friday WBIQ 10 4 10 10 10 10 6 p.m. FS1 St. John’s Red Storm at Drag Racing WCIQ 7 10 4 Creighton Blue Jays (Live) WVTM 13 13 5 5 13 13 13 13 Sunday Saturday WTTO 21 8 9 9 8 21 21 21 7 p.m. ESPN2 Summitracing.com 12 p.m. ESPN2 Vanderbilt Com- WUOA 23 14 6 6 23 23 23 NHRA Nationals from The Strip at modores at South Carolina WEAC 24 24 Las Vegas Motor Speedway in Las Gamecocks (Live) WJSU 40 4 4 40 Vegas (Taped) 2 p.m. -
On the Ball! One of the Most Recognizable Stars on the U.S
TVhome The Daily Home June 7 - 13, 2015 On the Ball! One of the most recognizable stars on the U.S. Women’s World Cup roster, Hope Solo tends the goal as the U.S. 000208858R1 Women’s National Team takes on Sweden in the “2015 FIFA Women’s World Cup,” airing Friday at 7 p.m. on FOX. The Future of Banking? We’ve Got A 167 Year Head Start. You can now deposit checks directly from your smartphone by using FNB’s Mobile App for iPhones and Android devices. No more hurrying to the bank; handle your deposits from virtually anywhere with the Mobile Remote Deposit option available in our Mobile App today. (256) 362-2334 | www.fnbtalladega.com Some products or services have a fee or require enrollment and approval. Some restrictions may apply. Please visit your nearest branch for details. 000209980r1 2 THE DAILY HOME / TV HOME Sun., June 7, 2015 — Sat., June 13, 2015 DISH AT&T CABLE DIRECTV CHARTER CHARTER PELL CITY PELL ANNISTON CABLE ONE CABLE TALLADEGA SYLACAUGA SPORTS BIRMINGHAM BIRMINGHAM BIRMINGHAM CONVERSION CABLE COOSA WBRC 6 6 7 7 6 6 6 6 AUTO RACING 5 p.m. ESPN2 2015 NCAA Baseball WBIQ 10 4 10 10 10 10 Championship Super Regionals: Drag Racing Site 7, Game 2 (Live) WCIQ 7 10 4 WVTM 13 13 5 5 13 13 13 13 Sunday Monday WTTO 21 8 9 9 8 21 21 21 8 p.m. ESPN2 Toyota NHRA Sum- 12 p.m. ESPN2 2015 NCAA Baseball WUOA 23 14 6 6 23 23 23 mernationals from Old Bridge Championship Super Regionals Township Race. -
Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases
University of Massachusetts Medical School eScholarship@UMMS Open Access Articles Open Access Publications by UMMS Authors 2020-03-11 Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases Brett D. Story Auburn University Et al. Let us know how access to this document benefits ou.y Follow this and additional works at: https://escholarship.umassmed.edu/oapubs Part of the Animal Experimentation and Research Commons, Investigative Techniques Commons, Musculoskeletal Diseases Commons, Nervous System Diseases Commons, Translational Medical Research Commons, and the Veterinary Medicine Commons Repository Citation Story BD, Miller ME, Bradbury AM, Million ED, Duan D, Taghian T, Faissler D, Fernau D, Beecy SJ, Gray- Edwards H. (2020). Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases. Open Access Articles. https://doi.org/10.3389/fvets.2020.00080. Retrieved from https://escholarship.umassmed.edu/oapubs/4183 Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 License. This material is brought to you by eScholarship@UMMS. It has been accepted for inclusion in Open Access Articles by an authorized administrator of eScholarship@UMMS. For more information, please contact [email protected]. REVIEW published: 11 March 2020 doi: 10.3389/fvets.2020.00080 Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases Brett D. Story 1,2, Matthew E. Miller 1, Allison M. Bradbury 3, Emily D. Million 4, Dongsheng Duan 4,5,6,7, Toloo Taghian 8, Dominik Faissler 9, -
Pedigree Analysis and Optimisation of the Breeding Programme of the Markiesje and the Stabyhoun
Pedigree analysis and optimisation of the breeding programme of the Markiesje and the Stabyhoun Aiming to improve health and welfare and maintain genetic diversity Harmen Doekes REG.NR.: 920809186050 Major thesis Animal Breeding and Genetics (ABG-80436) January, 2016 Supervisors/examiners: Piter Bijma - Animal Breeding and Genomics Centre, Wageningen University Kor Oldenbroek - Centre for Genetic Resources the Netherlands (CGN), Wageningen UR Jack Windig - Animal Breeding & Genomics Centre, Wageningen UR Livestock Research Thesis: Animal Breeding and Genomics Centre Pedigree analysis and optimisation of the breeding programme of the Markiesje and the Stabyhoun Aiming to improve health and welfare and maintain genetic diversity Harmen Doekes REG.NR.: 920809186050 Major thesis Animal Breeding and Genetics (ABG-80436) January, 2016 Supervisors: Kor Oldenbroek - Centre for Genetic Resources the Netherlands (CGN), Wageningen UR Jack Windig - Animal Breeding & Genomics Centre, Wageningen UR Livestock Research Examiners: Piter Bijma - Animal Breeding and Genomics Centre, Wageningen University Kor Oldenbroek - Centre for Genetic Resources the Netherlands (CGN), Wageningen UR Commissioned by: Nederlandse Markiesjes Vereniging Nederlandse Vereniging voor Stabij- en Wetterhounen Preface This major thesis is submitted in partial fulfilment of the requirements for the degree of Master of Animal Sciences of Wageningen University, the Netherlands. It comprises an unpublished study on the genetic status of two Dutch dog breeds, the Markiesje and the Stabyhoun. that was commissioned by the Breed Clubs of the breeds, the ‘Nederlandse Markiesjes Vereniging’ and the ‘Nederlandse Vereniging voor Stabij- en Wetterhounen’. It was written for readers with limited pre-knowledge. Although the thesis focusses on two breeds, it addresses issues that are found in many dog breeds. -
The Human Aura
The Human Aura Manual compiled by Dr Gaynor du Perez Copyright © 2016 by Gaynor du Perez All Rights Reserved No part of this book may be reproduced or distributed in any form or by any means without the written permission of the author. INTRODUCTION Look beneath the surface of the world – the world that includes your clothes, skin, material possessions and everything you can see - and you will discover a universe of swirling and subtle energies. These are the energies that underlie physical reality – they form you and everything you see. Many scientific studies have been done on subtle energies, as well as the human subtle energy system, in an attempt to verify and understand how everything fits together. What is interesting to note is that even though the subtle energy systems on the earth have been verified scientifically as existing and even given names, scientists are only able to explain how some of them work. Even though we do not fully comprehend the enormity and absolute amazingness of these energies, they form an integral part of life as we know it. These various energy systems still exist regardless of whether you “believe in them” or not (unlike Santa Claus). You can liken them to micro-organisms that were unable to be seen before the invention of the microscope – they couldn’t be seen, but they killed people anyway. We, and everything in the universe, is made of energy, which can be defined most simply as “information that vibrates”. What’s more interesting is that everything vibrates at its own unique frequency / speed, for example, a brain cell vibrates differently than a hair cell, and similar organisms vibrate in similar ways, but retain a slightly different frequency than the other. -
The Relation Between Canine Hip Dysplasia, Genetic Diversity and Inbreeding by Breed
Open Journal of Veterinary Medicine, 2014, 4, 67-71 Published Online May 2014 in SciRes. http://www.scirp.org/journal/ojvm http://dx.doi.org/10.4236/ojvm.2014.45008 The Relation between Canine Hip Dysplasia, Genetic Diversity and Inbreeding by Breed Frank H. Comhaire Department of Internal Medicine, Ghent University, Ghent, Belgium Email: [email protected] Received 18 March 2014; revised 18 April 2014; accepted 28 April 2014 Copyright © 2014 by author and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract Objectives: To assess the relation between the prevalence of canine hip dysplasia, inbreeding and genetic diversity by breed. Methods: Retrospective pedigree analysis of 9 breeds based on a ref- erence population of 41,728 individuals, and hip dysplasia assessment in 1745 dogs. Results: Hip dysplasia was less common among breeds with higher coefficient of inbreeding, lower genetic di- versity, and highest contribution of one single ancestor to the population. Inbreeding not exceed- ing 3.25% should be considered safe since it will maintain a sufficiently high genetic diversity within the breed. Clinical Significance: Together with published data on single breeds, the present findings question the general assumption that line-breeding or in-breeding has an adverse effect on the prevalence of hip dysplasia. Hip assessment is indicated in all breeds, but better methods are needed for selecting dogs suitable for reproduction. Keywords Genetic Diversity, Effective Population Size, Inbreeding, Hip Dysplasia 1. Introduction A high degree of inbreeding increases the probability of homozygosity of recessive genes, and enhances the risk of hereditary diseases coming to expression. -
CASE NO. SC06-156 V
IN THE SUPREME COURT OF FLORIDA PINKEY W. CARTER, Appellant, CASE NO. SC06-156 v. STATE OF FLORIDA, Appellee. ______________________/ ANSWER BRIEF OF APPELLEE BILL McCOLLUM ATTORNEY GENERAL CHARMAINE M. MILLSAPS ASSISTANT ATTORNEY GENERAL FLORIDA BAR NO. 0989134 OFFICE OF THE ATTORNEY GENERAL THE CAPITOL TALLAHASSEE, FL 32399-1050 (850) 414-3300 COUNSEL FOR THE STATE TABLE OF CONTENTS PAGE(S) TABLE OF CONTENTS ............................................ i TABLE OF CITATIONS ......................................... iii PRELIMINARY STATEMENT ........................................ 1 STATEMENT OF THE CASE AND FACTS............................... 1 SUMMARY OF ARGUMENT ......................................... 40 ARGUMENT.................................................... 45 ISSUE I WHETHER THE TRIAL COURT PROPERLY RULED THE STATUTE ABOLISHING THE INTOXICATION DEFENSE WAS CONSTITUTIONAL? (Restated).... 45 ISSUE II WHETHER THE TRIAL COURT PROPERLY FOUND THE MURDERS OF VICTIMS REED AND PAFFORD TO BE COLD, CALCULATED AND PREMEDITATED? (Restated) ............................................... 51 ISSUE III WHETHER THE TRIAL COURT PROPERLY FOUND AND INSTRUCTED THE JURY ON THE DURING THE COURSE OF A BURGLARY AGGRAVATOR? (Restated) ......................................................... 60 ISSUE IV WHETHER THE TRIAL COURT ABUSED ITS DISCRETION IN ASSIGNING GREAT WEIGHT TO TWO OF THE AGGRAVATORS? (Restated)......... 72 ISSUE V WHETHER THE TRIAL COURT’S SENTENCING ORDER IS SUFFICIENTLY CLEAR? (Restated) ....................................... -
<I>BOC</I> Is a Modifier Gene in Holoprosencephaly
Received: 12 May 2017 Revised: 20 June 2017 Accepted: 28 June 2017 DOI: 10.1002/humu.23286 BRIEF REPORT BOC is a modifier gene in holoprosencephaly Mingi Hong1∗ Kshitij Srivastava2∗ Sungjin Kim1 Benjamin L. Allen3 Daniel J. Leahy4 Ping Hu2 Erich Roessler2 Robert S. Krauss1† Maximilian Muenke2† 1Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, New York 2Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 3Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 4Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas Correspondence Robert S. Krauss (for editorial communication), Abstract Department of Cell, Developmental and Regen- Holoprosencephaly (HPE), a common developmental defect of the forebrain and midface, has a erative Biology, Icahn School of Medicine at complex etiology. Heterozygous, loss-of-function mutations in the sonic hedgehog (SHH) pathway Mount Sinai, New York, New York 10029. Email: [email protected] are associated with HPE. However, mutation carriers display highly variable clinical presentation, Maximilian Muenke, Medical Genetics Branch, leading to an “autosomal dominant with modifier” model, in which the penetrance and expressiv- National Human Genome Research Institute, ity of a predisposing mutation is graded by genetic or environmental modifiers. Such modifiers National Institutes of Health, Bethesda, Mary- land 20892. have not been identified. Boc encodes a SHH coreceptor and is a silent HPE modifier gene in mice. Email: [email protected] Here, we report the identification of missense BOC variants in HPE patients. Consistent with these ∗Mingi Hong and Kshitij Srivastava contributed alleles functioning as HPE modifiers, individual variant BOC proteins had either loss- or gain-of- equally to this work. -
Where Currents Connect
The Current GAHANNA PARKS & RECREATION ACTIVITY GUIDE Winter 2019-2020 Parks & Recreation WorkWhere in Gahanna? Receive the Currents Resident Discount Rate (RDR) Connect 1 Civic Leaders City of Gahanna Advisory Committees TABLE OF CONTENTS Mayor Tom Kneeland Parks & Recreation Board City Attorney Shane W. Ewald Meetings are held at 7pm on the second Civic Leaders 2 Wednesday of each month at City Hall Gahanna City Council unless otherwise noted. All meetings are Rental Facilities 3 Contact: [email protected] open to the public. Ward 1: Stephen A. Renner, Vice President Jan Ross, Chair Ward 2: Michael Schnetzer Andrew Piccolantonio, Vice Chair Aquatics 4 Ward 3: Brian Larick Cynthia Franzmann Ward 4: Jamie Leeseberg Chrissy Kaminski Active Seniors At Large: Karen J. Angelou Eric Miller 5 Nancy McGregor Daphne Moehring Brian Metzbower, President Ken Shepherd Parks Information 10 Parks & Recreation Staff Landscape Board Contact: [email protected] The Landscape Board meetings are listed online at Jeffrey Barr, Director Ohio Herb Center 11 www.gahanna.gov. Meetings are held at City Hall Stephania Bernard-Ferrell, Deputy Director unless otherwise noted. Alan Little, Parks & Facilities Superintendent All meetings are open to the public. Golf Course 12 Brian Gill, Recreation Superintendent Jane Allinder, Chair Jim Ferguson, Parks Foreman Melissa Hyde, Vice Chair Zac Guthrie, Parks & Community Services Supervisor Outdoor Experiences 13 Kevin Dengel Joe Hebdo, Golf Course Supervisor Mark DiGiando Curt Martin, Facilities Coordinator Matt Winger Camp Experiences 14 Sarah Mill, Recreation Supervisor Julie Predieri, City Forester Pam Ripley, Office Coordinator Arts & Education 15 Marty White, Facilities Foreman Recreation & Sports 16 How to register 19 Volunteer Advisory Committees The Parks & Recreation Board created the following advisory committees to assist the Department of Parks & Recreation with facilitating, planning, promoting and implementing projects with the assistance of volunteer residents. -
Review of the Current State of Genetic Testing - a Living Resource
Review of the Current State of Genetic Testing - A Living Resource Prepared by Liza Gershony, DVM, PhD and Anita Oberbauer, PhD of the University of California, Davis Editorial input by Leigh Anne Clark, PhD of Clemson University July, 2020 Contents Introduction .................................................................................................................................................. 1 I. The Basics ......................................................................................................................................... 2 II. Modes of Inheritance ....................................................................................................................... 7 a. Mendelian Inheritance and Punnett Squares ................................................................................. 7 b. Non-Mendelian Inheritance ........................................................................................................... 10 III. Genetic Selection and Populations ................................................................................................ 13 IV. Dog Breeds as Populations ............................................................................................................. 15 V. Canine Genetic Tests ...................................................................................................................... 16 a. Direct and Indirect Tests ................................................................................................................ 17 b. Single