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1~ OMB No 1545-0047 Form 990 1 Return of Organization Exempt From Income Tax Under section 501(c), 527, or 4947(a)(1) of the Internal Revenue Code (except black lung 2004 benefit trust or private foundation) Department of the Treasury Internal Revenue Service 10, The organization may have to use a copy of this return to satisfy state reporting requirements A For the 2004 calendar vear_ or tax year beainnina October 1 , 2004. and ending September 3 20 D Employer Identification number B Check if applicable please C Name of organization use IRS Eye and Ear Infirmary 04; 2103591 q Address change label or Massachusetts print or address) E Telephone number q Number and street (or P 0 box if mail is not delivered to street Room/suite Name change type. 243 Charles Street ( 617 ) 573-3012 q Initial return see Specific City or town, state or country, and ZIP + 4 q q Final return Instn+o - F Accounting method: Cash 0 Accrual tfons. Boston, MA 02114-3002 return El Other (specify) 1, H and I are not applicable to section 527 o anfzatfons q Application pending • Section 501(c)(3) organizations and 4947(a)(1) nonexempt charitable trusts must attach a completed Schedule A (Form 990 or 990-EZ). H(a) Is this a group return for affiliates ? Yes ® No www.meei.harvard.edu H(b) If "Yes," enter number of affiliates ► ...... G Website: ► H(c) Are all affiliates included? q Yes q No q q (If "No," attach a list. See instructions) J Organization type (check on ly one) ► 0 501(c) ( 3 ) i (insert no) 4947(a)(1) or 527 H(d) Is this a separate return filed by an K Check here q if the organization's gross receipts are normally not more than $25,000 The ► organization covered by a group ruling? q Yes ® No organization need not file a return with the IRS. but if the organization received a Form 990 Package complete return . in the mail, it should file a return without financial data Some states require a I Group Exemption Number ► q M Check ► if the organization is not required 121,240,462 L Gross receipts Add lines 6b, 8b, 9b, and 1 Ob to line 12 ► to attach Sch B (Form 990, 990-FZ, or 990-PF) Revenue, Expenses, and Chang es in Net Assets or Fund Balances (See pag e 18 of the instructions.) 1 Contributions, gifts, grants, and similar amounts received: a Direct public support ...... la 6,314,421 b Indirect public support ...... lb 1,686,000 c Government contributions (grants) ...... 1c 14,945,330 22,945,751 d Total (add lines 1a through 1c) (cash $ noncash $ ) , Id 2 Program service revenue including government fees and contracts (from Part VII , line 93) 2 97,851,788 3 Membership dues and assessments ...... 3 4 Interest on savings and temporary cash investments ...... 4 5 Dividends and interest from securities ...... 5 442,923 6a Gross rents ...... 6a b Less: rental expenses ...... 6b c Net rental income or (loss) (subtract line 6b from line 6a) ...... 6c 7 Other investment income (describe ► ) 7 (A) Securities (B) Other C 8a Gross amount from sales of assets other than inventory ...... 8a b Less: cost or other basis and sales expenses 8b c Gain or (loss) (attach schedule) . . . 8c d Net gain or (loss) (combl olumns (A) and (B)) ...... 8d q em 9 Sp et tFI (ach sc edule). If any amount is from gaming , check here ► Gr ss rev of Q a co n ons reported on line 1 ...... 9a b Les ' rec pe%s@ (26616th draismg expenses 9b ft,J c Net m ^r loss) from specs I nts (subtract line 9b from line 9a) . . . . . 9c QR 10a Gro s I tiszreturn and allowances 10a b Less cost U , , . . , , 10b c Gros rom sales of inventory (attach schedule) (subtract line 10b from line 10a) 10c 11 Other revenue (from Part VII, line 103) ...... 11 12 Total revenue (add lines 1d, 2, 3, 4, 5, 6c, 7, 8d, 9c, 1Oc, and 11) . 12 121,240,462 13 Program services (from line 44 , column (B)) 13 91,040,937 con' 14 Management and general (from line 44 , column (C)) ...... 14 15 34,322,254 aX 15 Fundraising (from line 44 , column (D)) ...... 16 Payments to affiliates (attach schedule) ...... 16 17 Total expenses (add lines 16 and 44, column (A)) 17 125,363,191 (4,122,729) 18 Excess or (deficit) for the year (subtract line 17 from line 12) ...... 18 19 Net assets or fund balances at beginning of year (from line 73 , column (A)) . . . 19 39,481,030 20 Other changes in net assets or fund balances (attach explanation)...... 20 1,943,398 z 21 Net assets or fund balances at end of year (combine lines 18, 19, and 20) 21 37,301,699 For Privacy Act and Paperwork Reduction Act Notice, see the separate instructions . Cat No 11282Y Form 990 (2004) ZIG jForm 990 (2004) Page 2 Statement of Al organizations must complete column (,4 Columns (B), (C), and (D) are required for section 501(c)(3) and (4) organizations Functional Expenses and section 4947(a)(1) nonexempt chantable trusts but optional for others (See page 22 of the instructions) Do not include amounts reported on line (A) Total (B) Program (C) Management (D) Fundrarsmg 6b, 8b, 9b, 10b, or 16 of Part I. services and general 22 Grants and allocations (attach schedule) . . (cash $ noncash $ ) 22 23 Specific assistance to individuals (attach schedule) 23 24 Benefits paid to or for members (attach schedule). 24 25 Compensation of officers , directors , etc. . 25 1,095,416 245,920 849,496 26 Other salaries and wages ...... 26 45,911,231 37,652,527 8,258,704 27 Pension plan contributions . . . . . 27 28 Other employee benefits ...... 28 5,895,667 1,944,168 3,951,499 29 Payroll taxes ...... 29 4,210,275 4,210,275 30 Professional fundraising fees . . . . . 30 31 Accounting fees ...... 31 52,225 (12,730) 64,955 32 Legal fees ...... 32 1 ,278 1,278 33 Supplies ...... - 33 16,020,634 15,894,702 125,932 34 Telephone ...... - 34 212,871 96,758 116,113 35 Postage and shipping ...... 35 123,917 51,237 72,680 36 Occupancy ...... 36 3,750,179 2,839,800 910,379 37 Equipment rental and maintenance . . . 37 2,845,258 1,780,519 1,064,739 38 Printing and publications . . . . . 38 204,171 143,202 60,969 39 Travel ...... 39 403,452 365,882 37,570 40 Conferences , conventions , and meetings 40 41 Interest ...... 41 1,604,296 1,604,296 42 Depreciation , depletion , etc. (attach schedule) 42 8,016,901 8,016,901 43 Other expenses not covered above (itemize)- a 43a b Bad Debt 43b 2,586,077 2,586,077 C Other------Expense ( See attached listing) -43c 32,429,343 30,038,952 2,390,391 43d d ------43e e ------44 Total functional expenses (add lines 22 through 43). Organizations completing columns (8)-(D), carry these totals to lines 13-15. 44 125,363,191 91,040,937 34,322,254 q Joint Costs. Check ► if you are following SOP 98-2. q Are any joint costs from a combined educational campaign and fundraising solicitation reported in (B) Program services? . ► Yes 0 No If "Yes," enter (i) the aggregate amount of these joint costs $ ; (ii) the amount allocated to Program services $ (iii) the amount allocated to Management and general $ and (iv) the amount allocated to Fundraising $ Statement of Program Service Accomplishments (See page 25 of the instructions.) Patient care and Research - See attachment What is the organization's primary exempt purpose? Program Service Expenses All organizations must descnbe their exempt purpose achievements in a clear and concise manner. State the number (Required for 501 (c)(3) and of clients served, publications issued, etc. Discuss achievements that are not measurable. (Section 501(c)(3) and (4) (4) orgs, and 4947(a)(1) trusts, but optional for organizations and 4947(a)( 1) nonexempt charitab le trusts must also enter the amount of grants and allocations to others.) others) a Hospital Services

(Grants and allocations $ ) 67,291,170 b _Research Activity ------•------

(Grants and allocations $ ) 749,767

C ......

(Grants and allocations $ )

d ......

(Grants and allocations $ e Other program services (attach schedule) (Grants and all ocations $ 91,040,937 f Total of Program Service Expenses (should equal line 44, column (B), Program services). . ► Form 990 (2004) 1 •(

worm 990 (2004) Page 3

Balance Sheets (See page 25 of the instructions.)

Note : Where required, attached schedules and amounts within the description (A) (B) column should be for end-of-year amounts only Beginning of year End of year 45 Cash-non-interest-bearing ...... 493,719 45 262,013 46 Savings and temporary cash investments ...... 46

47a Accounts receivable ...... 47a 10,810,093 b Less: allowance for doubtful accounts 47b 3, 186,672 10,525,237 47c 7,623,421

48a Pledges receivable ...... 48a b Less: allowance for doubtful accounts 48b 48c 49 Grants receivable ...... 49 50 Receivables from officers, directors, trustees, and key employees (attach schedule) ...... 50 51a Other notes and loans receivable (attach schedule) ...... 51a b Less: allowance for doubtful accounts 51b 51c 336,421 52 Inventories for sale or use ...... 1,395,644 52 1 , 53 Prepaid expenses and deferred charges . . 1,626 ,565 53 1 ,477,655 q q FMV 54 54 Investments-securities (attach schedule) . . ► Cost 55a Investments-land, buildings, and equipment: basis ...... 55a b Less : accumulated depreciation (attach schedule) ...... 55b 55c 56 Investments-other (attach schedule) 56 57a Land , buildings , and equipment: basis 57a 202,595,899 b Less: accumulated depreciation (attach 137,226,859 65 , 110,562 65,369,040 schedule) . . . . 57b 57c See attachment ) 14,636 , 150 58 26,403,986 58 Other assets (describe ►

59 Total assets (add lines 45 through 58) (must equal line 74) . 93,787,877 59 102 ,472,536 60 Accounts payable and accrued expenses ...... 22,590,445 60 22,828,083 61 Grants payable ...... 61 62 Deferred revenue ...... 62 yai 63 Loans from officers , directors , trustees, and key em ployees (attach schedule) ...... 63 0 64a Tax-exempt bond liabilities (attach schedule) ...... 25,604,038 64a 36,122,486 b Mortgages and other notes payable (attach schedule) . . . . . 64b See attachment ) 6,112 ,364 65 6,220,268 65 Other liabilities (describe ►

66 Total liabilities (add lines 60 through 65) 54,306 ,847 66 65 ,170,837 q Organizations that follow SFAS 117, check here ► and complete lines y 67 through 69 and lines 73 and 74. 39,481 ,030 67 37,301,699 6 67 Unrestricted ...... 68 Temporarily restricted . 68 M 69 Permanently restricted ...... 69 q Organizations that do not follow SFAS 117, check here ► and LL complete lines 70 through 74. 0 70 Capital stock , trust principal , or current funds ...... 70 71 Paid-in or capital surplus , or land , building , and equipment fund 71 y 72 Retained earnings , endowment , accumulated income , or other funds 72 a 73 Total net assets or fund balances (add lines 67 through 69 or lines Z 70 through 72; column (A) must equal line 19; column (B) must equal line 21) . 39,481 ,030 73 37,301,699 74 Total liabilities and net assets / fund balances (add lines 66 and 73) 93,787,877 74 102,472,536 Form 990 is available for public inspection and, for some people, serves as the primary or sole source of information about a particular organization. How the public perceives an organization in such cases may be determined by the information presented on its return. Therefore, please make sure the return is complete and accurate and fully describes, in Part III, the organization's programs and accomplishments. .Form 990 (2004) Page 4 Reconciliation of Revenue per Audited = Reconciliation of Expenses per Audited Financial Statements with Revenue per Financial Statements with Expenses per Return (See page 27 of the instructions.) Return a Total revenue , gains , and other support a Total ex penses and losses per per audited financial statements . ► a audited financial statements . . ► -A b Amounts included on line a but not on b Amounts included on line a but not line 12, Form 990: on line 17, Form 990: (1) Net unrealized gains (1) Donated services on investments. . $ and use of facilities $ (2) Donated services (2) Prior year adjustments and use of facilities $ reported on line 20, (3) Recoveries of prior Form 990. . . . $ year grants . . . $ (3) Losses reported on (4) Other (specify): line 20, Form 990. $ ...... (4) Other (specify): ------Add amounts on lines (1) through (4) pp. b ...... $ Add amounts on lines (1) through b Line minus line Line c a b . . . . . ► c c a minus line b . . . . . ► c d Amounts included on line 12, d Amounts included on line 17, Form 990 but not on line a: Form 990 but not on line a: (1) Investment expenses (1) Investment expenses not included on line not included on line 6b, Form 990. . . $ 6b, Form 990 . . $ (2) Other (specify): (2) Other (specify):

$ $

Add amounts on lines (1) and (2) ► d Add amounts on lines (1) and (2) ► d e Total revenue per line 12, Form 990 e Total expenses per line 17, Form 990 (line c plus line d. . ► e (line c p lus line d. ► e List of Officers, Directors , Trustees , and Key Employees (List each one even if not compensated; see page 27 of the instructions.) (B) Title and average hours per (C) Compensation (D) contributions to (E) Expense (A) Name and address week devoted to position (If not paid, enter employee benerd plans & account and other -0-.) deferred compensation allowances George R-- nek ------••------•-•------Chairman 0 0 0 181 Border Street, Cohasset, MA Joseph B. Nadol Jr., MD ------•- --- - Chief of Otolaryngology 0 0 0 243 Charles Street, Boston, MA Joan Miller, MD ------•---•-- --- Chief of 0 0 0 243 Charles Street, Boston, MA Joseph W Haley _ Vice Chariman 0 0 0 Exchange Place, Boston, MA Diane E. Kaneb ------• ------Vice Chairman 0 0 0 140 Orchad Avenue, Weston, MA William Darling, CPA Treasurer 0 0 0 27 School Street, Boston, MA James F. Sullivan ------•- ----•-.-- -... ------•----•------•--•---- Secretary 0 0 0 200 State Street , Boston, MA Lily Bentas ----•---•------•--•--•------•------•--•--••---- Director 0 0 0 777 Dedham Street, Canton, MA Frederick G. P. Thorne Director 0 0 0 20 Oak Street, Beverly Farms, MA Herbert Pollack ------•------••------•--•----• Director 0 0 0 25 Suzanne Road, Lexington, MA 75 Did any officer, director, trustee, or key employee receive aggregate compensation of more than $100,000 from your organization and all related organizations, of which more than $10,000 was provided by the related organizations? q Yes 0 No If "Yes," attach schedule-see page 28 of the instructions.

Form 990 (2004) Form 990 (2004) Page 5 ONW-0ther Information (See pag e 28 of the instructions. ) Yes No 3 76 Did the organization engage in any activity not previously reported to the IRS? If "Yes," attach a detailed description of each activity. 76 3 77 Were any changes made in the organizing or governing documents but not reported to the IRS? . 77 If "Yes , " attach a conformed copy of the changes . 3 78a Did the organization have unrelated business gross income of $1 , 000 or more during the year covered by this return? 78a b If "Yes , " has it filed a tax return on Form 990-T for this year? ...... 78b 3 79 Was there a liquidation , dissolution , termination , or substantial contraction during the year? If "Yes, " attach a statement 79 80a Is the organization related (other than by association with a statewide or nationwide organization) throug h common membership , governing bodies , trustees , officers , etc. , to any other exempt or nonexempt organization? . . 80a 3 See attached b If "Yes," enter the name of the organization ► ...... and check whether it is 0 exempt or q nonexempt 81a Enter direct and indirect political expenditures. See line 81 instructions 1 81a b Did the organization file Form 1120-POL for this year? ...... 81b 3 82a Did the organization receive donated services or the use of materials, equipment, or facilities at no charge or at substantially less than fair rental value? ...... 82a b If "Yes," you may indicate the value of these items here. Do not include this amount as revenue in Part I or as an expense in Part II. (See instructions in Part III.), 1 82b 83a Did the organization comply with the public inspection requirements for returns and exemption applications? 83a 3 b Did the organization comply with the disclosure requirements relating to quid pro quo contributions?. 83b 3 84a Did the organization solicit any contributions or gifts that were not tax deductible? ...... 84a 3 b If "Yes , " did the organization include with every solicitation an express statement that such contributions or gifts were not tax deductible? ...... 84b 85 501(c)(4), (5), or (6) organizations. a Were substantially all dues nondeductible by members? ...... 85a b Did the organization make only in-house lobbying expenditures of $2,000 or less? ...... 85b If "Yes" was answered to either 85a or 85b , do not complete 85c through 85h below unless the organization received a waiver for proxy tax owed for the prior year. c Dues, assessments, and similar amounts from members...... 85c d Section 162(e) lobbying and political expenditures...... 85d e Aggregate nondeductible amount of section 6033(e)(1)(A) dues notices. . . 85e f Taxable amount of lobbying and political expenditures (line 85d less 85e) . . 85f g Does the organization elect to pay the section 6033(e) tax on the amount on line 85f? ...... h If section 6033(e)(1)(A) dues notices were sent, does the organization agree to add the amount on line 85f to its reasonable estimate of dues allocable to nondeductible lobbying and political expenditures for the following tax year? ...... 85h 86 501(c)(7) orgs. Enter: a Initiation fees and capital contributions included on line 12 . 86a b Gross receipts , included on line 12 , for public use of club facilities . . . 86b 87 501(c)(12) orgs. Enter: a Gross income from members or shareholders . . . 87a b Gross income from other sources. (Do not net amounts due or paid to other sources against amounts due or received from them.) ...... 87b 88 At any time during the year, did the organization own a 50% or greater interest in a taxable corporation or partnership, or an entity disregarded as separate from the organization under Regulations sections 301.7701-2 and 301.7701-3? If "Yes," complete Part IX ...... 88 89a 501(c)(3) organizations. Enter: Amount of tax imposed on the organization during the year under: section 4911 ► 0 ; section 4912 ► 0 ; section 4955 ► 0 b 501(c)(3) and 501(c)(4) orgs. Did the organization engage in any section 4958 excess benefit transaction 3 during the year or did it become aware of an excess benefit transaction from a prior year? If "Yes," attach a statement explaining each transaction ...... 89b c Enter. Amount of tax imposed on the organization managers or disqualified persons during the year under sections 4912, 4955, and 4958 ...... ► d Enter: Amount of tax on line 89c, above, reimbursed by the organization . . . . ► Massachusetts and New York 90a List the states with which a copy of this return is filed ► b Number of employees employed in the pay penod that includes March 12, 2004 (See instructions.) 190b 1 1334 Peter J_ Chinetti, Vice President for Finance. 617 ) 573-3012 91 The books are in care of ► Telephone no. ► (. _ 243 Charles Street , Boston , MA ZIP + 4 P211 4-3002 Located at ► ► •. . •--•--- q 92 Section 4947(a)(1) nonexempt charitable trusts filing Form 990 in lieu of Form 1041-Check here...... ► and enter the amount of tax-exempt interest received or accrued durinq the tax year . . . ► 192 I Form 990 (2004) • Form 990 (2004) Page 6 Analysis of Income-Producin g Activities (See pag e 33 of the instructions. ) Unrelated business income Excluded by section 512, 513, or 514 (E) Note : Enter gross amounts unless otherwise Related or indicated. (A) (B) (C) (D) exempt function Business code Amount Exclusion code Amount income 93 Program service revenue: a Inpatient and outpaient revenue b Service Revenue 73 ,231,002 c Other Operating Income - see attachment 24,620,786 d e f Medicare/Medicaid payments . . . . . g Fees and contracts from government agencies 94 Membership dues and assessments . . . 95 Interest on savings and temporary cash investments 96 Dividends and interest from securities . . 14 97 Net rental income or (loss) from real estate: a debt-financed property ...... b not debt-financed property ...... 98 Net rental income or (loss) from personal property 99 Other investment income ...... 100 Gain or (loss) from sales of assets other than inventory 101 Net income or (loss) from special events . 102 Gross profit or (loss) from sales of inventory 103 Other revenue, a b c d e 104 Subtotal (add columns (B), (D), and (E)) 98,294,711 105 Total (add line 104, columns (B), (D), and (E)) ...... ► Note: Line 105 olus line 1d. Part I. should equal the amount on line 12, Part I. Relationshi p of Activities to the Accomp lishment of Exempt Purposes (See pag e 34 of the instructions. ) Line No. Explain how each activity for which income is reported in column (E) of Part VII contributed importantly to the accomplishment y of the organization's exempt purposes (other than by providing funds for such purposes). 93(b) Patient care 93(c) Patient care (See attached list)

Information Regardin g Taxable Subsidiaries and Disregarded Entities (See page 34 of the instructions.) A (B) (C) Name, address, and EIN of corporation, Percentage of End- Eryear arnershi , or disreg arded entity ownershi p interest Nature activities Total(Dcome assets

Information Regarding Transfers Associated With Personal benefit contracts (See page 34 of the instructions.) (a) Did the organization, during the year, receive any funds, directly or indir (b) Did the organization, during the year, pay premiums, dlr Note : If "Yes" to (b), file Form 8870 and Form 4720 (see in Under penaltie of perjury , I declare that I have examined this return and belief is corr nd comp a Declaration of prepare Please Sign Signature of ofri r Here Peter J. Chinetti, Vice President for Finance Type or print name and title

Paid Preparers' signature Preparer's Firm ' s name (or yours Use Only if self-employed), address. and ZIP + 4 `SCHEDULE A Organization Exempt Under Section 501(c)(3) OMB No 1545-0047 (Form 990 or 990-EZ) (Except Private Foundation) and Section 501(e), 501(f), 501(k), 501(n), or Section 4947(a)(1) Nonexempt Charitable Trust Supplementary Information-(See separate instructions.) 2004 Department of the Treasury Internal Revenue Service ► MUST be completed by the above organizations and attached to their Form 990 or 990-EZ Name of the organization Employer identification number Massachusetts Eye and E ar Infi 04:2103591 Compensation of the Five Highest Paid Employees Other Than Officers, Directors, and Trustees (See page 1 of the instructions. List each one. If there are none, enter "N one.") Contributions Expense Name and address of each employee paid more (b) Title and average hours ( d) to (e) (a) c) Compensation e mployee benefit plans & account and other devoted ( than $50,000 per week to position deferred compensation allowances See Attached Listing

------••-•--•------

------

Total number of other employees paid over 386 $50,000. ► FTM Compensation of the Five Highest Paid Independent Contractors for Professional Services (See page 2 of the instructions. List each one (whether individuals or firms). If there are none, enter "None.")

(a) Name and address of each independent contractor paid more than $50,000 (b) Type of service (c) Compensation

Ropes and Gray Attorneys

One International Place , Boston, MA

Fish and Richardson PC Attorneys

225 Franklin Street , Boston, MA

Testa, Hurwitz and Thibeault Attorneys 125,751 High Street Tower, Boston, MA

Price Waterhouse Coopers Auditors 118,220 P.O. Box 3026 , Boston, MA

Fish and Neave Attorneys -----•-•---- 114,439 1251 Avenue of Americas

Total number of others receiving over $50,000 for professional services . . ► 1 For Paperwork Reduction Act Notice, see the Instructions for Form 990 and Form 990-E. Cat No 11285F Schedule A (Form 990 or 990-EZ) 2004 Schedule A (Form 990 or 990-EZ) 2004 Page 2 Statements About Activities (See page 2 of the instructions.) Yes No

1 During the year, has the organization attempted to influence national, state, or local legislation, including any attempt to influence public opinion on a legislative matter or referendum? If "Yes," enter the total expenses paid 43,415 or incurred in connection with the lobbying activities ► $ (Must equal amounts on line 38, Part VI-A, or line i of Part VI-B) ...... 1 Organizations that made an election under section 501(h) by filing Form 5768 must complete Part VI-A. Other organizations checking "Yes" must complete Part VI-B AND attach a statement giving a detailed description of the lobbying activities. 2 During the year, has the organization, either directly or indirectly, engaged in any of the following acts with any substantial contributors, trustees, directors, officers, creators, key employees, or members of their families, or with any taxable organization with which any such person is affiliated as an officer, director, trustee, majority owner, or principal beneficiary? (If the answer to any question is "Yes,"attach a detailed statement explaining the transactions.)

a Sale, exchange, or leasing of property? ...... 2a 3 3 b Lending of money or other extension of credit? ...... 2b c Furnishing of goods, services , or facilities? ...... 2c 3 d Payment of compensation (or payment or reimbursement of expenses if more than $1 ,000)? ...... 2d 3 e Transfer of any part of its income or assets? ...... 2e 3 3a Do you make grants for scholarships, fellowships, student loans, etc.? (If "Yes," attach an explanation of how you determine that recipients qualify to receive payments.) ...... 3a b Do you have a section 403(b) annuity plan for your employees ? ...... 3b 3 4a Did you maintain any separate account for participating donors where donors have the right to provide advice 3 on the use or distribution of funds? ...... 4a b Do you provide credit counseling, debt management, credit repair, or debt negotiation services? 4b 3 Reason for Non-Private Foundation Status (See pages 3 through 6 of the instructions.)

The organization is not a private foundation because it is: (Please check only ONE applicable box.) 5 q A church, convention of churches, or association of churches. Section 170(b)(1)(A)(i). 6 q A school. Section 170(b)(1)(A)(i). (Also complete Part V.) 7 0 A hospital or a cooperative hospital service organization. Section 170(b)(1)(A)(ui). 8 q A Federal, state, or local government or governmental unit. Section 170(b)(1)(A)(v). 9 q A medical research organization operated in conjunction with a hospital. Section 170(b)(1)(A)(ui). Enter the hospital 's name, city, and state 10 q An organization operated for the benefit of a college or university owned or operated by a governmental unit. Section 170(b)(1)(A)(iv). (Also complete the Support Schedule in Part IV-A.) 11a q An organization that normally receives a substantial part of its support from a governmental unit or from the general public. Section 170(b)(1)(A)(w). (Also complete the Support Schedule in Part IV-A.) 11b q A community trust. Section 170(b)(1)(A)(v). (Also complete the Support Schedule in Part IV-A.) 12 q An organization that normally receives: (1) more than 331/3% of its support from contributions, membership fees, and gross receipts from activities related to its charitable, etc., functions-subject to certain exceptions, and (2) no more than 331/0% of its support from gross investment income and unrelated business taxable income (less section 511 tax) from businesses acquired by the organization after June 30, 1975. See section 509(a)(2). (Also complete the Support Schedule in Part IV-A.) 13 q An organization that is not controlled by any disqualified persons (other than foundation managers) and supports organizations described in: (1) lines 5 through 12 above; or (2) section 501(c)(4), (5), or (6), if they meet the test of section 509(a)(2). (See section 509(a)(3).) Provide the following information about the supported organizations. (See page 5 of the instructions.) I (b) Line number (a) Name(s) of supported organization(s) from above

14 q An organization organized and operated to test for public safety. Section 509(a)(4). (See page 5 of the instructions.) Schedule A (Form 990 or 990- EZ) 2004 "Schedule A (Form 990 or 990-EZ) 2004 Page 3 JjMEM Support Schedule (Complete only if you checked a box on line 10, 11, or 12.) Use cash method of accounting. Nnte' You may use the worksheet in the instructions for convertina from the accrual to the cash method of accounting. Calendar year (or fiscal year beginning in) ► (a) 2003 (b) 2002 (c) 2001 (d) 2000 (e) Total 15 Gifts, grants, and contributions received. (Do not include unusual grants. See line 28.). 16 Membership fees received 17 Gross receipts from admissions, merchandise sold or services performed, or furnishing of facilities in any activity that is related to the organization's charitable, etc., purpose . . 18 Gross income from interest, dividends, amounts received from payments on securities loans (section 512(a)(5)), rents, royalties, and unrelated business taxable income (less section 511 taxes) from businesses acquired by the organization after June 30, 1975 19 Net income from unrelated business activities not included in line 18. 20 Tax revenues levied for the organization's benefit and either paid to it or expended on its behalf ...... 21 The value of services or facilities fumished to the organization by a governmental unit without charge. Do not include the value of services or facilities generally furnished to the public without charge . 22 Other income. Attach a schedule. Do not include gain or (loss) from sale of capital assets 23 Total of lines 15 through 22 . 24 Line 23 minus line 17 . 25 Enter 1 % of line 23 26a 26 Org anizations described on lines 10 or 11: a Enter 2% of amount in column (e) , line 24 . . . . ► b Prepare a list for your records to show the name of and amount contributed by each person (other than a governmental unit or pu bl icly supported organ ization) whose total g ifts for 2000 through 2003 exceeded the 26b amount shown in line 26a. Do not file this list with your return . Enter the total of all these excess amounts ► 26C c Total su pport for section 509(a)(1) test: Enter line 24 , column (e) ...... ► d Add: Amounts from column (e) for lines: 18 19 26d 22 26b ...... ► 26e e Public support (line 26c minus line 26d total) ...... ► f Public support percentage (line 26e (numerator) divided by line 26c (denominator)) . ► 26f % 27 Organizations described on line 12: a For amounts included in lines 15, 16, and 17 that were received from a "disqualified person," prepare a list for your records to show the name of, and total amounts received in each year from, each "disqualified person." Do not file this list with your return . Enter the sum of such amounts for each year.

(2003) ------(2002) ------(2001) ------(2000) ------b For any amount included in line 17 that was received from each person (other than "disqualified persons"), prepare a list for your records to show the name of, and amount received for each year, that was more than the larger of (1) the amount on line 25 for the year or (2) $5,000. (Include in the list organizations described in lines 5 through 11, as well as individuals.) Do not file this list with your return . After computing the difference between the amount received and the larger amount described in (1) or (2), enter the sum of these differences (the excess amounts) for each year: (2003) ------(2002) ------(2001) ------(2000) ...... ------

c Add: Amounts from column (e) for lines: 15 16 17 20 21 d Add: Line 27a total. and line 27b total e Public support (line 27c total minus line 27d total)...... 1110. f Total support for section 509(a)(2) test: Enter amount from line 23, column (e) . . ► L g Public support percentage (line 27e (numerator) divided by line 27f (denominator)) . . . . ► h Investment income percentage (line 18, column (e) (numerator) divided by line 27f nominator)). ► 28 Unusual Grants: For an organization described in line 10, 11, or 12 that received any unusual grants during 2000 through 2003, prepare a list for your records to show, for each year, the name of the contributor, the date and amount of the grant, and a brief description of the nature of the grant. Do not file this list with your return. Do not include these grants in line 15. Schedule A (Form 990 or 990- EZ) 2004 Schedule A (Form 990 or 990-EZ) 2004 Page 4 Private School Questionnaire (See page 7 of the instructions.) (To be completed ONLY by schools that checked the box on line 6 in Part IV) Yes No 29 Does the organization have a racially nondiscriminatory policy toward students by statement in its charter, bylaws , other governing instrument, or in a resolution of its governing body? ...... 29 30 Does the organization include a statement of its racially nondiscriminatory policy toward students in all its brochures , catalogues , and other written communications with the public dealing with student admissions, programs, and scholarships? ...... 30 31 Has the organization publicized its racially nondiscriminatory policy through newspaper or broadcast media during the period of solicitation for students , or during the registration period if it has no solicitation program, in a way that makes the policy known to all parts of the general community it serves? ...... 31 If "Yes," please describe; if "No," please explain. (If you need more space, attach a separate statement.) ------

------32 Does the organization maintain the following: a Records indicating the racial composition of the student body, faculty, and administrative staff? . . . . . 32a b Records documenting that scholarships and other financial assistance are awarded on a racially nondiscriminatory basis? ...... 32b c Copies of all catalogues, brochures, announcements, and other written communications to the public dealing with student admissions, programs, and scholarships? ...... 32c d Copies of all matenal used by the organization or on its behalf to solicit contributions ? ...... 32d

If you answered "No" to any of the above, please explain. (If you need more space, attach a separate statement.) ------33 Does the organization discriminate by race in any way with respect to:

a Students' rights or privileges? ...... LVja

b Admissions policies? ...... 33b

c Employment of faculty or administrative staff? ...... 33c

d Scholarships or other financial assistance? ...... 33d

e Educational policies? ...... 33e

f Use of facilities ? ...... 33f

g Athletic programs? ......

h Other extracurricular activities? ...... 33h

If you answered "Yes" to any of the above, please explain. (If you need more space, attach a separate statement.) ------

34a Does the organization receive any financial aid or assistance from a governmental agency? ...... Ma

b Has the organization's right to such aid ever been revoked or suspended? ...... b If you answered "Yes" to either 34a or b, please explain using an attached statement.

35 Does the organization certify that it has complied with the applicable requirements of sections 4.01 through 4.05 of Rev. Proc. 75-50, 1975-2 C.B. 587, covering racial nondiscrimination? If "No," attach an explanation . . Schedule A (Form 990 or 990-EZ) 2004 Schedule A (Form 990 or 990-EZ) 2004 Pag e 5 Lobbying Expenditures by Electing Public Charities (See page 9 of the instructions.) (To be completed ONLY by an eligible organization that filed Form 5768) q q provisions apply. Check ► a if the organization belongs to an affiliated group. Check ► b if you checked "a" and "limited control"

Expenditures To be Limits on Lobbying Affiliated group completed for ALL electing totals (The term "expenditures" means amounts paid or incurred.) organizations 36 Total lobbying expenditures to influence public opinion (grassroots lobbying) . . . . 36 37 Total lobbying expenditures to influence a legislative body (direct lobbying) . . . . . 37 38 Total lobbying expenditures (add lines 36 and 37) ...... 38 39 Other exempt purpose expenditures ...... 39 40 Total exempt purpose expenditures (add lines 38 and 39) ...... 40 41 Lobbying nontaxable amount. Enter the amount from the following table- If the amount on line 40 is- The lobbying nontaxable amount is- Not over $500,000 ...... 20% of the amount on line 40 . . . . . Over $500,000 but not over $1 ,000,000 . $100, 000 plus 15% of the excess over $500,000 Over $1 ,000,000 but not over $1 ,500,000 $175, 000 plus 10% of the excess over $1,000,000 41 Over $1,500,000 but not over $17,000,000. $225,000 plus 5% of the excess over $1,500,000 Over $17 ,000,000 ...... $1 ,000, 000 ...... 42 Grassroots nontaxable amount (enter 25% of line 41) ...... 42 43 Subtract line 42 from line 36. Enter -0- if line 42 is more than line 36...... 43 44 Subtract line 41 from line 38. Enter -0- if line 41 is more than line 38...... 44

Caution : If there is an amount on either line 43 or line 44, you must file Form 4720. 4-Year Averaging Period Under Section 501(h) (Some organizations that made a section 501(h) election do not have to complete all of the five columns below. See the instructions for lines 45 through 50 on Dage 11 of the instructions.)

Lobbying Expenditures During 4-Year Averaging Period

Calendar year (or (a) (b) (c) (d) (e) fiscal year beginning in) ► 2004 2003 2002 2001 Total

45 Lobbying nontaxable amount

46 Lobbying ceiling amount (150% of line 45(e))

47 Total lobbying expenditures .

48 Grassroots nontaxable amount .

49 Grassroots ceiling amount (150% of line 48(e))

50 Grassroots lobbying expenditures . LjULWIC -i Lobbying Activity by Nonelecting Public Charities (For reporting only by organizations that did not complete Part VI-A) (See page 11 of the instructions.)

During the year, did the organization attempt to influence national, state or local legislation, including any Yes No Amount attempt to influence public opinion on a legislative matter or referendum, through the use of: a Volunteers ...... b Paid staff or management (Include compensation in expenses reported on lines c through h.) . . . c Media advertisements ...... d Mailings to members, legislators, or the public ...... e Publications, or published or broadcast statements ...... f Grants to other organizations for lobbying purposes ...... g Direct contact with legislators, their staffs, government officials, or a legislative body. . . . 3 43,415 h Rallies, demonstrations, seminars, conventions, speeches, lectures, or any other means . . i Total lobbying expenditures (Add lines c through h.) ...... 43,415 If "Yes" to any of the above, also attach a statement giving a detailed description of the lobbying activities. Schedule A (Form 990 or 990-EZ) 2004 Schedule A (Form 990 or 990-EZ) 2004 Page 6 Information Regarding Transfers To and Transactions and Relationships With Noncharitable Exempt Organizations (See page 11 of the instructions.) 51 Did the reporting organization directly or indirectly engage in any of the following with any other organization described in section 501(c) of the Code (other than section 501 (c)(3) organizations) or in section 527, relating to political organizations? a Transfers from the reporting organization to a nonchantable exempt organization of: Yes No (i) Cash ...... 51 a i 3 (ii) Other assets ...... a(ii) 3 b Other transactions: / (i) Sales or exchanges of assets with a noncharitable exempt organization ...... bb(i) (ii) Purchases of assets from a nonchantable exempt organization ...... b ii (iii) Rental of facilities, equipment, or other assets ...... b iii 3 (iv) Reimbursement arrangements ...... b iv 3 (v) Loans or loan guarantees ...... b(v) 3 (vi) Performance of services or membership or fundraising solicitations ...... b vi 3 3 c Sharing of facilities, equipment, mailing lists, other assets, or paid employees ...... c d If the answer to any of the above is "Yes," complete the following schedule. Column (b) should always show the fair market value of the goods, other assets, or services given by the reporting organization. If the organization received less than fair market value in any transaction or sharing arrangement, show in column (d) the value of the goods, other assets, or services received. (a) (b) (c) (d) Line no Amount involved Name of nonchantable exempt organization Description of transfers, transactions, and sharing arrangements 51(c) 103,100 Circle Company, Inc. Reimbursement for Infirmary personnel and supplies used by Circle Compamv, Inc.

51(bliii 1 35.0041 Circle Company. Inc. I Rental paid for use of facilities

52a Is the organization directly or indirectly affiliated with, or related to, one or more tax-exempt organizations described in section 501(c) of the Code (other than section 501 (c)(3)) or in section 527? ...... ® Yes q No b If "Yes," complete the following schedule: (a) (b) (c) Name of organization Type of organization Description of relationship Circle Company , Inc. 501 (c)(25) Circle Company is an exempt 501 (c) (25) oraanization operated exclusively for the benefit

Ear Infirmary, Inc. the parent of the Massachusetts Eve and Ear Infirmary.

Schedule A (Form 990 or 990-EZ) 2004 Massachusetts Eye and Ear Infirmary Form 990 Employer Identification Number - 04-2103591 September 30, 2005

Part 1

Part a Direct Public Support 6,314,421

Part b Indirect Public Support Subsidies from the Foundation of MEEI 1,686,000

Part c Government Grants 14,945,330

Part I, Line 4 - Dividends and Interest from Securitii 442,923

Line 20 - Other changes in net assets of fund balanct Unrealized loss (116,433) Transfers to affiliates 3,785,125 Adjustment fo minimum pension liability (1,725,294) 1,943,398 Form 8868 (Rev 12-2004) Page 2 q3 • If you are filing for an Additional (not automatic) 3-Month Extension , complete only Part II and check this box . . ► Note . Only complete Part II if you have already been granted an automatic 3-month extension on a previously filed Form 8868. • If you are filing for an Automatic 3-Month Extension , complete only Part I (on page 1) Additional (not automatic) 3-Month Extension of Time-Must File Orig in I and One Copy, Type or Name of Exempt Organization Employer identification number print Massachusetts Eye and Ear Infirmary 04: 2103591 File by the Number, street, and room or suite no If a P 0 box, see instructions For IRS use only extended 243 Charles Street due date for filing the City, town or post office, state, and ZIP code For a foreign address, see instructions return See instructions Boston , MA 02114 Check type of return to be filed (File a separate application for each return)- 0 Form 990 q Form 990-T (sec 401(a) or 408(a) trust) q Form 5227 q Form 990-BL q Form 990-T (trust other than above) q Form 6069 q Form 990-EZ q Form 1041-A q Form 8870 q Form 990-PF q Form 4720 STOP: Do not complete Part II if you were not already granted an automatic 3-month extension on a previously filed Form 8868. • Tne books are in the care of D _Peter J Chinettl, Vice President for Finance -__617 ) 573-3012------...... (___617--_)------573-3021 Telephone No. ► FAX No . 0- • If the organization not have an office or place of business the United States, check q does in this box ...... ► • If this is for a Group Return , enter the organization's four digit Group Exemption Number (GEN) If this is q q for the whole group , check this box ► . If it is for part of the group, check this box ► and attach a list with the names and EINs of all members the extension is for 4 I request an additional 3-month extension of time until -Arrgust 15 _2p 06 5 For calendar year ...... or other tax year beginning ...... October 1 , 2 0 4 , and ending ___ September 30 20 05 6 If this tax year is for less than 12 months, check reason- q Initial return q Final return q Change in accounting period 7 State in detail why you need the extension .More --time------is needed for complete------and accurate filing------of tax returns.

------8a If this application is for Form 990-BL, 990- PF, 990-T, 4720, or 6069, enter the tentative tax, less any nonrefundable credits. See instructions ...... $ b If this application is for Form 990-PF, 990-T, 4720, or 6069, enter any refundable credits and estimated tax payments made Include any prior year overpayment allowed as a credit and any amount paid previously with Form 8868 ...... $ c Balance Due. Subtract line 8b from line 8a. Include your payment with this form , or, if required , deposit with FTD coupon or, if required , by using EFTPS (Electronic Federal Tax Payment System). See instructions. $ Signature and Verification Under penalties of perjury, I declare that I have examined this form, including accompanying schedules and statements , and to the best of my knowledge and belief, it is true, correct , and omplete , and that I a uthornzed to prepare this form 1 j Vice President for Finance Signature ► Title ► Date ► S/ a G Notice to -Applicant-To Be Completed by the IRS - We have approved this application Please attach this form to the organization ' s return q We have not approved this application However, we have granted a 10-day grace period from the later of the date shown below or the due date of the organization 's return (including any prior extensions) This grace period is considered to be a valid extension of time for elections otherwise required to be made on a timely return . Please attach this form to the organization ' s return q We have not approved this application . After considering the reasons stated in item 7, we cannot grant your request for an extension of time to file We are not granting a 10-day grace period q We cannot consider this application because it was filed after the extended due date of the return for which an extension was requested q Other

By Director Date Alternate Mailing Address - Enter the address if you want the copy of this application for an a d; to slop returned to an address different than the one entered above Name MAY 2 9 2000

Type I Number and street ( include suite , room, or apt. no.) or a P.O. box number or F IELD DIRECIun' print «c,K,a OGDEN, City or town, province or state, and country (including postal or ZIP code)

Form 8868 (Rev 12-2004) Form 8868 Application for Extension of Time To File an (Rev December 2004) Exempt Organization Return OMB No 1545-1709 Department of the Treasury Internal Revenue Service No- File a separate application for each return. • If you are filing for an Automatic 3-Month Extension, complete only 3q Part I and check this box ...... ► • If you are filing for an Additional (not automatic) 3-Month Extension , complete only Part II (on page 2 of this form). Do not complete Part ll unless you have already been g ranted an automatic 3-month extension on a previously filed Form 8868. FOM Automatic 3-Month Extension of Time-Only submit original (no copies needed)

Form 990-T corporations requesting an automatic 6-month q extension-check this box and complete Part I only . . . ► All other corporations (including Form 990-C filers) must use Form 7004 to request an extension of time to file income tax returns. Partnerships, REMICs, and trusts must use Form 8736 to request an extension of time to file Form 1065, 1066, or 1041. Electronic Filing (e -file). Form 8868 can be filed electronically if you want a 3-month automatic extension of time to file one of the returns noted below (6 months for corporate Form 990-T filers). However, you cannot file it electronically if you want the additional (not automatic) 3-month extension, instead you must submit the fully completed signed page 2 (Part II) of Form 8868. For more details on t h e e l ec tron ic filing of thi s fo rm, vis it www.irs.gov/efile.

Type or Name of Exempt Organization Employer identification number print Massachusetts Eye and Ear Infirmary 04: 2103591 File by the Number, street, and room or suite no If a P.O box, see instructions. due date for filing your 243 Charles Street return See instructions City, town or post office, state, and ZIP code For a foreign address, see instructions Boston, MA 02114 Check type of return to be filed (file a separate application for each return): 3q Form 990 q Form 990-T (corporation ) q Form 4720 q Form 990-BL q Form 990-T (sec. 401(a) or 408 (a) trust) q Form 5227 q Form 990-EZ q Form 990-T (trust other than above) q Form 6069 q Form 990-PF q Form 1041-A q Form 8870

• The books are in the care of J. Chinetti, Vice President for Finance

(__617_ _ 617 ) 573-3012 _ _617 ) 573-3021 Telephone No. ► FAX No. ► (_ ------• q If the organization does not have an office or place of business in the United States, check this box ...... ► • If this is for a Group Return , enter the organization's four digit Group Exemption Number (GEN) If this q q is for the whole group, check this box ► . If it is for part of the group, check this box ► and attach a list with the names and EINs of all members the extension will cover I request an automatic 3-month (6-months for a Form 990 -T corporation) extension of time until _May 15 _ 20 06 to file the exempt organization return for the organization named above. The extension is for the organization's return for: q ► calendar year 20 __ or 3q ...... October. 1 20 ...... September 30 2005 ► tax year beginning 94, and ending

2 If this tax year is for less than 12 months, check reason. q Initial return q Final return q Change in accounting period

3a If this application is for Form 990-BL, 990-PF, 990-T, 4720, or 6069, enter the tentative tax, less any nonrefundable credits. See instructions ...... $ b If this application is for Form 990-PF or 990-T, enter any refundable credits and estimated tax payments made Include any prior year overpayment allowed as a credit ...... $ c Balance Due. Subtract line 3b from line 3a Include your payment with this form, or, if required, deposit with FTD coupon or, if required, by using EFTPS (Electronic Federal Tax Payment System). See instructions ...... $ Caution . If you are going to make an electronic fund withdrawal with this Form 8868, see Form 8453-EO and Form 8879-EO for payment instructions.

For Privacy Act and Paperwork Reduction Act Notice , see Instructions . Cat No 27916D Form 8868 (Rev 12-2004) FORM 990 PROGRAM MANAGEMENT SEPT . 30, 2005 SERVICES & AND Tax ID. 04-2103591 FUND ACTIVITY GENERAL GRAND Massachusetts Eye and Ear Infirmary TOTAL #700547170 TOTAL

OTHER EXPENSE - Part II - Line 43c PURCHASED SERVICES 1,825,834 04 613,163 44 2,438,997 48 DUES 22,021 96 218,095 00 240,116 96 FOOD - MEAT, FISH & PULTRY 269 01 269 01 FOOD - OTHER 908,913 46 80,587 73 989,501 19 MISC 2 ,844,632 01 639,087 64 3,483,719 65 ADVERTISING 20,194 50 155,731 62 175,926 12 UNIFORMS 28,999 49 0 00 28,999 49 FRINGE BENEFITS GROUP HEALTH 0 00 0 00 COLLECTION 0 00 253,132 68 253,132 68 PURCHASED CLERICAL 11,115 64 0 00 11,115 64 QUALITY ASSISTANCE 40,738 63 40,738 63 PROFESSIONAL FEES 0 00 0 00 PURCHASED LAB SERVICES 1,401, 518 88 1 ,401,518 88 DISPOSAL SERVICE 65,177 38 65,177 38 PHOTOCOPY CHARGES (10,974 15) (10,974 15) GENERAL 1,300,328 97 0 00 1,300,328 97 CREDIT CARD FEES 0 00 105,782 37 105,782 37 MERCHANDISING 0 00 0 00 ADMINISTRATIVE EXPENSE 82,076 04 82,076 04 INVENTORY ADJUSTMENT 41,965 91 41,965 91 A & T PAYBACK 2,723,955 96 2,723,955 96 MISC. LIBRARY SERVICES (11,939 55) (11,939 55) OTHER EXPENSES 1,189,632 90 0 00 1,189,632 90 OFFSITE PARKING 79,660 00 79,660 00 RECRUITING ADVERTISING 0 00 51,735 63 51,735 63 SUBSIDIZED EXPENSES (78,275 45) (435,579 86) (513,855 31) EMPLOYEE INCENTIVES 0 00 7,876 58 7,876 58 RECRUITMENT 0 00 645 00 645 00 PROFESSIONAL FEES 1,792,127 39 254,433 78 2,046,561 17 SUBCONTRACTS 2,141,007 01 2,141,007 01 Patient Care 75,451.64 75,451 64 DIRECT SUPPORT SERVICES 13,617,054 76 13,617,054 76 TRANSFER - OTHER (10,799 72) (10,799 72) TRANS TO/FR FOUNDATION SPECIAL (61,735.00) (61,735 00) TRANS TO/FR FOUNDATION SPECIAL 0.00 0 00 TSA MATCH 445,699 60 445,699 60 TOTAL 30,038,951 71 2,390,391 21 32,429,342 92 Massachusetts Eye and Ear Infirmary Form 990 Employer Identification Number - 04-2103591 September 30, 2005

Part III - Statement of Program Service Accomplishments

A. Hospital Services - Patient Care The Massachusetts Eye and Ear Infirmary is a not-for-profit teaching hospital conducting patient care and research. The Massachusetts Eye and Ear Infirmary is a teaching hospital of and an international center for research. It has the most competitive program in the country for eye and ear, nose and throat training and the world's largest ophthalmic fellowship program.

B. Research Activity - See attachment 04-2103591

report of the

C H I E F O F

O T O L A R Y N G O L O G Y

The mission of the Department of Otolaryngology at the Head and Neck Surgical Oncology Service

Massachusetts Eye and Ear Infirmary (MEEI) is to provide Vicente Resto, M D , was appointed as the first the best possible care for patients with disorders that Dingman fellow in Head and Neck/Microvascular affect the ear, nose, throat, head and neck regions, to Reconstructive Surgery Daniel Deschler, M D., served conduct clinical and basic research in an effort to improve as the keynote speaker for the annual meeting of that care in the future; to participate in the education the International Association of Laryngectomees and training of future healthcare and research profes- James Rocco, M.D., has begun a clinical research effort sionals, and to disseminate health-related information to evaluating the use of novel anti- the profession and to the general public. medications to treat head and neck neoplasia Derrick

Lin, M D , the newest member of the Division, is

P A T I E N T C A R E, C L I N I C A L evaluating the potential use of Cox-2 inhibitors in the

A N D T R A N S L A T I O N A L R E S E A R C H management of head and neck tumors

General Otolaryngology Service Laryngology Service and Voice and Speech Laboratory Under the direction of Gregory Randolph, M D , the Ramon Franco, Jr, M D , was appointed as director of

Ii subspecialty areas of interest include disorders of smell the Division of Laryngology, which offers comprehensive and taste, the nose and paranasal sinuses, and sleep care for benign and malignant laryngeal lesions, airway apnea Eric Holbrook, M.D , has been appointed to the reconstruction, and neurolaryngologic disorders The Research Grant Committee of the American Rhinologic Division plans a Harvard Search for a senior investigator Society. Salah Salman, M D.'s, second book, "Atlas of to serve as the director of the Mosher Laryngology Diagnostic Nasal Endoscopy," was published in 2004. Research Laboratory

Thyroid and Parathyroid Surgery Service In October, the Voice and Speech Laboratory had its This is the first full year of operation of the Thyroid and first open house for voice teachers and students in the Parathyroid Surgery Service at MEEI Dr Randolph New England area served as a faculty member in a number of national and

international symposia in the area of thyroid and Facial Plastic and Reconstructive Surgery Service

parathyroid disease and has founded The National The Facial Nerve Clinic, under the direction of Tessa Endocrine Surgery Study Group. Hadlock, M D , has increased the number of patient

visits internationally. Dr. Hadlock is the recipient of a 04-2103591 training grant from the NIH for research to improve undergone cochlear implantation. Michael McKenna, surgical outcomes in facial nerve injuries Mack Cheney, M D , continues his work in the molecular of

M D., Director of this Service, was honored with the otosclerosis annual Humanitarian Award by the American Academy The Cochlear Implant Research Laboratory, under of Facial Plastic and Reconstructive Surgery in the direction of Donald Eddington, Ph.D., is investi- recognition of his plastic surgical missions in Latin gating the potential benefits of bilateral cochlear America Richard Gliklich, M D , received funding for implantation, particularly in the area of fusion and evaluation of a new minimally invasive procedure in localization of sound facial plastic surgery The Audiology Department, under the direction of Sharon Kujawa, Ph D., provides an outstanding Pediatric Otolaryngology Service comprehensive and diagnostic and rehabilitative service Under the direction of Roland Eavey, M D , this Service to patients of all ages at three clinical sites In addition, 17 provides unique subspecialty services to patients such the Audiology Department performs intraoperative as the Vascular Malformations Clinic, organized by nerve monitoring, both at MEEI and MGH, and performs Michael Cunningham, M.D , and the Pediatric Voice, newborn hearing screening at four area hospitals Dr. Airway, and Swallowing Clinic, an interdepartmental Kujawa collaborates with Charles Liberman, Ph D., effort with Pediatric Gastroenterology and Pulmonary Director of the Eaton-Peabody Laboratory (EPL), and Services at MGH, and directed by Chris Hartnick, M D with Bruce Tempel at the University of Washington in a The research efforts of the Division include study of study funded by NIDCD on the genetics of susceptibility subglottic stenosis funded by a K08 award to Leila to noise-induced hearing loss Chris Halpin, Ph D , in Mankarious, M D., and a tissue engineering effort to collaboration with Dr Rauch, is a co-investigator on provide safer and more reliable methods for tracheal an NIH-funded multi-center clinical trial of oral versus reconstruction organized by Dr Hartnick In addition to his responsibilities as Director of the residency training program, Dr Cunningham is president-elect of the American Society of Pediatric Otolaryngology Dr

Hartnick successfully launched a clinical fellowship in Pediatric Otolaryngology

Otology, Neurotology, Audiology, Cochlear Implant Research Laboratory, and Vestibular Laboratory Clinical members of the Otology/Neurotology Service have developed complementary subspecialty areas of interest Thus, Saumil Merchant, M D , in conjunction with John Rosowski, Ph D , continues his basic and translational research in the mechanics of the middle ear His research also includes pathology of the ear Steven Rauch, M D , has grant support to study the management of sudden hearing loss I am studying the pathology of the inner ear in individuals who in life had 04-2103591

intratympanic steroids for sudden hearing loss The Department's annual public forum "Have You Heard?" was sponsored late in 2005 and was well attended by members of the lay public

New space has allowed the vestibular group to accept approximately $2.5 million of new research grants from NASA Lionel Zupan, Ph D , is the PI on

one grant and Daniel Merfeld, Ph D , on another The caring for laboratory also is involved in the development of the community implantable neural-vestibular prostheses

BASIC R E S E A R C H

The MEEI and its physicians continued their During the year there were several noteworthy commitment to providing service to the community accomplishments by members of our research faculty through a variety of protects, including screenings, > Dr Albert Edge described an in vitro system in lectures and participation in health fairs The hospi- which progenitors of neural cells form neural tal's Vision and Hearing Care Program cared for the projections and connections with hair cells which increasing numbers of children at the Neighborhood will allow systematic study of the stem cell types House Charter School in Dorchester, Mass In and chemical conditions required to optimize the addition to the screenings at MEEI's "adopted regrowth of cochlear nerve fibers school," staff also provided a vision screening, in collaboration with Boston City Council Member > Dr Jennifer Melcher demonstrated a strong Michael Ross, at the Amy Lowell Apartments in correlation between the listener's perception and Boston The Audiology Department's fifth annual neuronal activity as demonstrated by functional Have You Heard" seminar, organized by Sharon MRI in an area of the auditory cortex, thus

Kulawa, Ph D , was a resounding success And providing clues as to the mechanisms and finally, many physicians worked behind the scenes anatomic locations of auditory perception. to provide free care, some of which helped children > Drs Sharon Kujawa and Charles Liberman from all over the world, as well as the victims of demonstrated that noise damage to the inner ear Hurricane Katnna early in life renders the ear more vulnerable to age-related deterioration Above Dr Sandra Montezuma, first-year ophthal-

mology resident, screens a child for pedi- > Drs McKenna, Merchant, Adams and their atric vision problems co-workers identified that osteoprotegerin 1 controls bone remodeling around the inner ear It is possible that malfunctions in this molecular

mechanism may underlie disease states of the inner ear such as otosclerosis. 04-2103591

> Haobing Wang, working with Dr Merchant E D U C A T I O N A L M I S S I O N and other investigators in EPL, developed an This year saw several successful courses and symposia. interactive, virtual, three-dimensional model of Nov 19-20, 2004 - "Surgery of the Thyroid and

the human temporal bone that holds promise for Parathyroid Glands," directed by Dr Randolph, April teaching and for research 29-30, 2005 - "Voice Disorders Update" directed by Dr Franco, and June 24, 2005, Dr Ernest Weymuller

NEW GRANT S discussed "Outcomes Research in the Management of

> A 5-year grant from NIDCD to Drs McKenna, Cancer of the Head and Neck " Sewell and Kujawa for collaborative work with In conjunction with our colleagues at the Children's Draper Laboratories to design and develop an Hospital, Beth Israel Deaconess Medical Center, and implantable drug-delivery microdevice for the Brigham and Women's Hospital, the Department

inner ear continues sponsorship of its combined residency training 19 and program in Otolaryngology Head and Neck Surgery > A 3-year grant from NIDCD to Dr Albert Edge In fiscal year 2005, the Department hosted 18 research for stem cell transplantation as a mechanism for fellows and 25 visiting colleagues from 14 countries regeneration of the inner ear

>A 5-year grant from NIDCD to Dr Bertrand PROFESSIONAL S T A F F Delgutte to study responses of cells in the auditory Congratulations are in order for the promotion of Dr central nervous system John Rosowski to the rank of Professor of Otology and Laryngology. We welcome several new members of the > A 5-year research grant from NIDCD to Dr John medical staff. Drs Joshua Kessler, Dukhee Rhee, David Guinan to study the function of tiny mechanical Roberson and Jeannie Chung as otolaryngologists on motions within the hair cells of the inner ear the part-time faculty, and Drs Donald Kearny, Jr,

> A 5-year research grant to Drs Saumil Merchant (Pediatric Otolaryngology), Dr Stacey Gray (General and John Rosowski to study sound transmission Otolaryngology, MEET), Dr Michael Rho (General in the normal and diseased middle ear to develop Otolaryngology, North Suburban Center), Dr Sherif better methods of reconstruction Ammar (General Otolaryngology, South Suburban Center), and Dr Jennifer Smullen (Otology/Neurotology,

On May 11, 2005, the Tillotson Laboratory of Cell MEEI) on the full-time faculty Biology of the Inner Ear opened on the third floor of The Department is grateful to its patients, staff the Connecting Building. The important research work and the MEEI Board of Directors for their confidence, to be carried out here will be supported in part by the help and support for making this a successful year newly developed James Wiggins Professorship in Otology and Laryngology

We are pleased to announce the recruitment of Ruth Anne Eatock, Ph D , to the EPL Currently a Joseph B. Nadol, Jr., M.D. Professor at Baylor College of Medicine, her special Chief of Otolaryngology interest is the biophysics of hair cells, both in hearing and vestibular end organs 04-2103591

report of the

CHIEF O F

O P H T H A L M O L O G Y

The MEEI Department of Ophthalmology closed 2005 Director of Uveitis/Immunology while we search for a with an admirable list of accomplishments and permanent director Dr Papaliodis is board-certified in 11 great ambitions for the coming year. As Chair of both Internal Medicine and Ophthalmology The search

Ophthalmology at Harvard Medical School, I have the for a new faculty member resulted in the opportunity to observe departments across the country, recruitment of Dr Douglas Rhee, who joined our and I assure you that the MEET represents the finest in practice this fall A graduate of the University of Michigan, service, ingenuity and scholarship Dr Rhee comes to us from Wills Eye Hospital,

Philadelphia, where he specialized in complicated

CLINICAL CARE glaucoma surgery and pediatric glaucoma We have

Our faculty offers the fullest array of ophthalmologic several searches still underway, and look forward to services to patients The numbers tell some of the successfully recruiting additional faculty to story over 28,000 patient encounters in the Comprehensive Ophthalmology, Pediatrics, Vision

Comprehensive Ophthalmology Service (COS) and Rehabilitation, Neuro-Ophthalmology and Cornea. over 141,000 across the Department The faculty, We are also proud of the clinical and professional fellows and residents of MEEA also provided 3,695 staff who bring their skills to patients around the world surgeries in the Infirmary operating rooms and 1,500 Christine Ament, M D , third-year resident, Thomas procedures in the Laser Center Merrill, Optical Services, and Jill Beyer, Contact Lens

Some important recruitment has been accom- Service, participated in an eye surgical mission to El plished this year Dr Joseph Rizzo became Director of Salvador Sarwat Salim, M D , Comprehensive

Neuro-Ophthalmology, succeeding Dr Simmons Ophthalmology Service & Glaucoma Service, joined a

Lessell Board-certified in Ophthalmology and medical mission team in Guatemala. Aaron Fay, M D ,

Neurology, Dr Rizzo is a pioneer in the field of artificial Oculoplastics Service, visited India as part of ORBIS intelligence and perception In Uveitis/Immunology, Dr International, an ophthalmic educational organization

C Stephen Foster resigned as director to open a private which focuses on upgrading local physicians' skills practice He remains a member of the academic Roberto Pineda, M D , Cornea and Refractive Surgery

Department and on staff at the Infirmary We are Service, went to Ethiopia with ORBIS pleased to have Dr George Papaliodis serving as Acting 04-2103591

R E S E A R C H experiences , initiated by Sandra Cremers, M D , and

A number of treatments developed in part in our Bonnie An Henderson, M D , of the Comprehensive

research laboratories were approved for patient care this Ophthalmology Service (COS) Its second component year This year, Macugen'" joined the ophthalmic is a set of standardized criteria to evaluate surgical armamentarium , and we learned the exciting results of performance, developed by Dr Cremers In addition, clinical trials using Lucentis" Building on research done Dr. Henderson is working with Dr John Loewenstein, in MEEI's Research Institute, co-directed by Residency Program Director, and other colleagues to

Evangelos Gragoudas, M D., former MEEI scientist create "Virtual Mentor," a software program that

Anthony Adamis, M D , and myself, these drugs repre- simulates cataract surgery, allowing residents to sent the next generation of AMD treatment Lucentis" practice procedures, make surgical mistakes, and refine results have shown for the first time that drug treatment their skills "virtually " can improve vision in patients with AMD Several faculty members received public acclaim for

The Harvard Medical School's Residents in significant research contributions this year- Thaddeus

Ophthalmology Cataract Outcomes Study was devel- Dryla, M D , Eliot Berson, M D , and Michael Sandberg, oped to study and improve resident surgical training Its Ph D., for work describing a previously unknown genetic first component is a compilation of resident surgical mutation that interferes with retinal cell signaling,

Cynthia Grosskreutz, M D , Ph D , for identifying a

protein involved in cell death in glaucoma, Tiansen Li,

Ph D , for the role of an enzyme, LOXL1, in age-related

loss of elasticity in tissues; and Johanna Seddon, M D.,

for studies of the role of inflammatory biomarkers in

patients with AMD

Several of our clinician scientists received new federal

research grants Janey Wiggs, M D , Ph.D , was awarded

a 5-year grant from the National Eye Institute (NIH) for

her genetics studies in glaucoma Kathryn Colby, M D.,

Ph.D , received a grant from the New England Corneal

Transplant Research Fund. Louis Pasquale, M D , Co-

Director of the Glaucoma Service, received 5-year funding

from the NIH to study gene-environment interactions in

glaucoma. Joseph Rizzo, M D, was awarded a grant from

the U.S. Defense Advanced Research Projects Agency to develop an interface between the retina and a custom- designed simulator chip, sometimes referred to as an "artificial retina." 04-2103591

E D U C A T I O N

The duty to teach future ophthalmologists and train tomorrow's scientists is an obligation we take seriously and find professionally satisfying Eighty medical students selected our service for elective rotations, allowing us to give them a glimpse of the exciting future that is possible in ophthalmology Eight new residents began in July, and our new Fellows have begun their clinical training and research.

An exciting development in training this past year was the first Intensive Cataract Surgical Training Course open to U S ophthalmology residents who have completed their second year of training. Held in early

June, and directed by Bonnie An Henderson, M.D , and myself, the course was offered free to participants, thanks to private industry and departmental support

One hundred and fifty residents participated As a result of its success, we will be offering this course again in 2006

Our commitment to ongoing training for faculty and practitioners remains strong We had an impressive roster of visiting lecturers, among them speakers from specialist Claes Dohlman, M D , received an Alcon

Harvard Medical School, University of Wisconsin, Research Award and garnered additional honors as a

University of California at San Francisco, U S. Food and World Congress Medal winner at the Cornea World

Drug Administration, National Eye Institute of NIH, and Congress V in April Marlene Durand, M D , Infectious

Duke University Medical Center For the 601 year, Disease consultant, received the 2005 HMS 50th the department offered the Lancaster Course in Anniversary Scholars-in-Medicine MEEI fellowship At

Ophthalmology, under the direction of Lucy H Y the American Academy of Ophthalmology meeting in

Young, M D , Ph D Kathryn Colby, M.D., Ph D , October, three MEEI researchers were honored continues the Professional Development Series she Thaddeus Dryja, M D , Ophthalmic Pathology, was implemented last year to address important professional awarded the Zimmerman Medal and delivered the issues that are not directly scientific or clinical, such Zimmerman Lecture, Johanna M Seddon, M D , Sc.M , as promotion, compliance, intellectual property, received the first Dr Maurice F Rabb, Jr, Award, and mentoring, conflict of interest and authorship Deborah Langston, M D , won the Thygeson Plaque

MEEI Ophthalmology faculty members were and delivered the Thygeson Lecture The Association honored with a number of prestigious awards Cornea for Research in Vision and Ophthalmology (ARVO) 04-2103591

The year 2005 was a challenging year fiscally for

our clinical practice and our research funding

Therefore, I am quite pleased that Ophthalmology has

been able to achieve a modest surplus, invest in new

faculty, and expand our teaching The generosity of

patients and other donors has allowed us to complete

funding for the Osler Professorship and build toward

the funding goals of three other endowed Chairs

Grants and awards for research continue at a high level,

with nearly $3 2 million in funds from government,

industrial, and foundation sources providing funding

for ophthalmic research this year We acknowledge

with a special note of gratitude the continued funding

from the charitable foundations which have supported

us over the years in research on blinding eye disease

Massachusetts Lions, Lions Clubs International Foundation,

Research to Prevent Blindness, Knights Templar Eye

Foundation, The Glaucoma Foundations, Inc , and the announced that Evangelos Gragoudas, M D., Director Ruth and Milton Steinbach Fund, Inc of the Retina Service. was selected as the 2006 winner It has been a busy and productive year in of the Mildred Weisenfeld Award Finally, I was Ophthalmology. My report would not be complete named a recipient of the 2006 ARVO/ Ophthalmics without an expression of gratitude to the Board and

Translational Research Award for work in elucidating Administration for their support, to our patients and the causes of and developing treatments for AMD friends, and to our untiring nurses, technicians and

Academic promotion is an important recognition of administrative staff, whose work underlies so much of faculty contributions to the field of Ophthalmology We our success I look forward to a future of creativity and are pleased to acknowledge individuals who have gained unsurpassed clinical and research advances from our promotion in academic rank Kathryn Colby, M.D., Ph.D., department Cornea Service, promoted to Assistant Professor, Aaron

Fay, M .D., Oculoplastics Service, promoted to Assistant Clinical Professor, Bonnie An Henderson, M.D., Iv PT'eK^

Comprehensive Ophthalmology Service, promoted to Joan W. Miller, M.D.

Assistant Professor; Jonathan Talamo , M.D., in community Chief of Ophthalmology practice, promoted to Associate Clinical Professor; and

Laney Wiggs , M.D., Ph .D., Glaucoma Service, promoted to Associate Professor. 04-2103591 2005 statistics

Inpatient Hospital 42 beds O T O L A R Y N G O L O G Y

D I S C H A R G E S Infirmary 43,067

Eye Discharges 287 Stoneham Center 11,545

ENT Discharges 976 Quincy Center 14,509

Total 1 ,263 Wellesley Center 9,254

Patient Days 4,224 Total 78,375

Average Length of Stay 3 34 Total Outpatient Visits 190,144

Surgical Procedures Emergency Room

INPATIENT SURGERY Total Visits 21,984

Eye Cases 230

ENT Cases 788 Special Services

Total 1,018 AUDIOLOGY DEPARTMENT

A M B U L A T 0 R Y S U R G E R Y Outpatient Visits 13,785

Eye Cases 12,968 Hearing Aid Center 3,267

ENT Cases 6,550 Evoked Response 1,256

Total 19 , 518 Newborn Audiology Screenings 3,641

Total Surgical Procedures 20,536 R A D I 0 L 0 G Y D E P A R T M E N T

Ambulatory Surgical Cases Utilizing Observation Service 2,904 Conventional Exams 2,731

CT Scan 13,960

Outpatient Department MRI 2,801

OPHTHALMOLOGY L A B O R A T O R I E S

General Eye 26,701 Bacteriology (Cultures) 12,019

Glaucoma 18,578 Clinical Lab (Procedures) 66,997

Cornea 10,072 ENT Pathology (Specimens) 14,521

Retina 22,457 Eye Pathology (Specimens) 2,810

Immunology 5,038 Frozen Section Laboratory 2,334

Neuro-Ophthalmology 4,840 Electrocardiograms 3,671

Pediatric Ophthalmology and Strabismus 4,135 Fluorescein Angiography 10,203

Eye Plastic 4,353 Occupational Therapy 2,333

Electroretinography 4,892 Optical Shop 3,236

Vision Rehabilitation 2,490 Ultrasonography 7,149

Contact Lens 4,679 Vestibular Laboratory 5,506

Methuen Center 2.076 Voice and Speech Laboratory 12,445

Stoneham Center 1,458 Hyperbaric Oxygen Treatments 3,722

Total 111,769 Massachusetts Eye and Ear Infirmary Form 990 Employer Identification Number - 04-2103591 September 30, 2005

Part II Line 42 Depreciation Building 4,204,774 Fixed Equipment 587,885 Major Movable 2,973,250 Minor Movable 250,992 8,016,901

Part IV Line 57 - Land, Building & Equipment Accumulated Cost Depreciation Leasehold Improvements 562,155 562,155 Land 524,701 Land Improvements 10,623 10,623 Building and Improvements 100,215,472 59,164,786 Fixed Equipment 26,695,009 21,874,572 Major Movable 69,099,835 54,012,309 Minor Movable 3,455,263 1,559,558 Construction in Progress 1,925,994 Auto 44,773 42,857 Capitalized Interest 62,073 202, 595,898 137,226,859

Line 58 - Other Assets Due from affiliates 22,687 Funds held for research 25,132 Accrued Interest Receivable 29,688 Construction Fund 10,503,752 Debt Service Fund 1,138,149 Special Cash Reserves Fund 9,737,128 Debt Service Reserves Fund 4,501,709 Deferred Financing Costs 445,741 26,403,986

Line 65 - Other Liabilities Due to affiliates 2,576,175 Estimated final settlements due to third-party payo 2,668,044 Accumulated postretirement benefit obligation 354,354 Professional liability reserve 621,695 6.220.268 Massachusetts Eye and Ear Infirmary Form 990 Employer Identification Number - 04-2103591 September 30, 2005

Part IV Line 64 - Notes Payable

Massachusetts Health and Educational Facilites Authority Revenue Bonds, Series B with Principal payments commencing in 1999 with interest rates varying from 4.00% to 5.25% collateralized by gross receipts 22,427,486

Massachusetts Health and Educational Facilites Authority Revenue Bonds , Series M-3A Pool Fund Principal payments ranging from $582,491 in 2006 to $1,316,957 in 2020 with a variable interest rate (2.67% at September 30, 2005) 13,695,000

Total Notes Payable 36,122,486 Massachusetts Eye and Ear Infirmary Form 990 Employer Identification Number - 04-2103591 September 30, 2005 Fringe Expense Part V (continued) Compensation Benefits Account

F. Curtis Smith 243 Charles Street Boston, MA 02114 President 369,649 66,498 0

Peter J. Chinetti 243 Charles Street Boston, MA 02114 Vice President for Finance 239,859 45,109 0

Barbara Katz 243 Charles Street General Counsel and Boston, MA 02114 Assistant Secretary 239,988 45,130 0

Carol Covell 243 Charles Street Boston, MA 02114 Senior V.P. For Patient Services 245,920 46,108 0

Mary Kearney 197 8th Street Charlestown, MA Director 0 0 0

Wayne Mackie 231 Country Drive Weston, MA Director 0 0 0

Paul Donahue 170 Newbury Street Boston, MA Director 0 0 0

Cyhthia L. Grosskreutz, MD 243 Charles Street Boston, MA Director 0 0 0

Vivain Beard One Beacon Street Boston, MA Director 0 0 0

Richard C. Aldrich 79 Cambridge Parkway Cambridge, MA Director 0 0 0

Michael Ervolini 11 Beacon Street Boston, MA Director 0 0 0

David N. Saul 1776 Heritage Drive - JAB 5 East Quincy, MA Director 0 0 0

David W. Scudder 600 Atlantic Avenue Boston, MA Director 0 0 0

Shaun R. Levesque 50 Oak Point Wrentham, MA Director 0 0 0 'f .

04-2103591

ASSOCIATE STAFF 1977 John O'Sullivan Francis 1996 Ron Zwanziger 2002 Stanley M Schurgln

Associate Radiologist 1977 Sandra Carnegie Steele 1997 Philip DuBois, Ph D 2002 The Honorable Robert E Travaglini R Gilberto Gonzalez, M D 1979 William H Claflm, IV 1997 Harvey F Lodish, Ph D 2002 Barry B Yellen

1979 Mrs Ernest J Sargeant 1997 Herbert W Pollack 2003 Ann Mane Cotton EMERITUS STAFF 1980 Thomas M Reardon (through 12/7/05) 1997 L Dennis Shapiro 2003 Robert P Fitzgerald Consultant in Radiotherapy 1981 Joseph Auerbach 1997 Robert D Sweeney 2003 William D Haylon Milford Schulz, M D 1981 John C Kane, Jr 1997 Vincent Vitto 2003 Matthew Lorber 1982 Jonathan M Keyes 1998 Richard J Chaffin 2003 Roberta W Siegel CONSULTING STAFF 1983 Ephraim Friedman, M D 1998 Cheryl L Clarkson 2003 Terence Wong

Clinical Associate in Radiology 1983 John F Palmer 1998 Renee M Landers 2004 Shawn Burke, Ph D Jeanne D Keller, M D 1984 Sheldon A Buckler, Ph D 1998 Christopher E Nolin 2004 Michael A Greeley Clinical Associate in Radiology 1984 Richard A MacKinnon 1999 Peter C Aldrich 2004 Marlyn McGrath Lewis

Herman D Suit, M D 1984 George J Rabstelnek 1999 Samuel Altschuler 2004 Christian B Snook 1985 Karen K Chandor 1999 Nancy Jo Altschuler 2005 David E Clem 1985 John Dowling, Ph D 1999 Andrew C Culbert 2005 John D DesPrez, III Administration 1985 Mrs Bruce Silver 1999 JoAnne Dickinson 2005 Fay Donohue President 1986 George Berkowitz 1999 Gerard F Doherty 2005 Ruth Ellen Fitch F Curtis Smith 1986 Alexander A Bernhard 1999 Richard L Kobus 2005 Catherine E Grein 31 General Counsel 1986 James S Cook, Emeritus 1999 Dr Jacqueline W Libergott 2005 William E James Barbara F Katz 1986 Diane E Kaneb 1999 John H Marenghi 2005 Janet B James Vice President for Human Resources 1986 Peter S Lynch 1999 Suzanne Murray 2005 David Loeser Christine Regan 1986 Malcolm L Sherman 1999 Eugenia "Gene" Seamans 2005 Joseph A Milano Vice President for Finance 1987 Winthrop G Minot 1999 John Larkin Thompson 2005 Karen L O'Connor, Ph D Peter J Chinetti 1988 William H Darling, C PA 1999 Wat Tyler 2005 Ann M Stockbridge Executive Vice President for Patient Services 1988 Charles F Kiefer, III 2000 Sol Boucai Carol Covell, R N , M S 1988 William E Roman 2000 Georgette Boucai

Vice President for Development 1988 Kenneth R Rossano 2000 Richard I Freedman Board of Directors

and Public Affairs 1989 Alan J Dalby 2000 David A Gladstone (As of 12/7/05) Bruce Jordan 1989 William G Lavelle, M D 2000 Robert C Jordan, Jr George 1 Rabstejnek, Chairman Vice President for Business Development 1989 1 Louis Newell, Jr 2000 John E Kavanagh, III Joseph W Haley, Vice-Chairman Lisa Putukian 1991 Professor Elliott L Atamian 2000 Jonathan W Kutchins Diane E Kaneb, Vice-Chairman

Administrative Director for Ophthalmology 1991 W Gerald Austen, M D 2000 Mrs August R Meyer (through 12/7/05) William H Darling, C PA, Treasurer Karen Smith 1991 Rufus L Grason (through 12/7/05) 2000 Carol Sawyer Parks James F'Sullivan, Sr, Secretary Chief Information Officer 1991 James F Sullivan, Sr 2000 Phyllis Redstone Richard H Aldrich Anne Fitzgerald (until June 4, 2004) 1993 Lucille Batal 2000 Robert H Rines Vivian C Beard Rick Mason (effective Jan 3, 2005) 1993 Claes H Dohlman, M D 2000 David N Saul Lily H Bentas Administrative Officer for Otolaryngology 1994 Yu Sing Jung 2000 Gordon H Silver Paull Donahue Jean MacQuiddy 1994 Loretta McLaughlin 2000 William B Smith Mike Ervolmi

Chief Facilities Planning Officer 1994 Ruth Z Nadol 2000 Polly Townsend Cynthia L Grosskreutz, M D , Ph D Robert Biggio 1995 Vivian C Beard 2001 Richard H Aldrich (through 12/7/05)

Director of Research Administration 1995 Paul J Donahue 2001 Joyce M Cummings Mary E Kearney Elayn Byron (until Dec 3, 2004) 1995 Joseph W Haley 2001 Michael A Ervolim Wayne D Mackie

Michael Collins (effective July 24, 2005) 1995 Mary E Kearney 2001 Karen F Green Saumil Merchant, M D (as of 12/7/05) Chief Financial Officer, MEEA 1995 Charles H Kouyoumpan 2001 William E Gundy Joan W Miller, M D Kenneth Holmes (through 12/07/05) 2001 Douglas R Stockbridge Joseph B Nadol, Jr, M D 1995 Patncia McGovern (through 12/7/05) Herbert W Pollack 1995 Wayne D Mackie 2002 E Lorraine Baugh David N Saul

Trustees 1995 David W Scudder 2002 Patricia H Brandes David W Scudder (As of December 7, 2005) 1996 William F Allen, Jr 2002 John P Driscoll, Jr F Curtis Smith

1965 Mrs John Lowell, Honorary 1996 Mrs W Dixie Reynolds Doreau , Honorary 2002 Donald J Evans Frederick G P Thorne 1967 William F Spang 1996 James F Gerrity, III 2002 Carol L Horvitz Chairman Emeritus 1967 Monte J Wallace 1996 Anil Khosla 2002 Anna Faith Jones Alexander A Bernhard

1971 Mrs Robert C Meisel 1996 Nelson YS Kiang, PhD 2002 Christopher P Kauders Sheldon A Buckler, Ph D 1972 Matthew J Burns 1996 Jack Klugman, Honorary 2002 Shaun R Levesque Director Emeritus 1972 Mrs William P Ellison 1996 Donald M Perrin 2002 Mary T Marshall Richard A MacKinnon 1973 Robert T P Storer, Jr 1996 John T Preston 2002 Denise Porter William F Spang 1973 Frederick G P Thorne 1996 Rand K Spero 2002 Daniel J Quirk

1974 Bruce A Beal 1996 Janet Zwanziger 2002 Barry 5 Scheur, J D Massachusetts Eye and Ear Infirmary Form 990 Employer Identification Number - 04-2103591 September 30, 2005

Part VI Line 80b

Foundation of the Massachusetts Eye and Ear Infirmary, Inc. 04-2785453 - exempt

Massachusetts Eye and Ear Associates, Inc. 22-2658209 - exempt

Embankment Services, Inc. 04-3272965 - exempt

Circle Company, Inc. 04-2801797 - exempt Massachusetts Eye and Ear Infirmary Form 990 Employer Identification Number - 04-2103591 September 30, 2005

Part VII - Line 93C - Other Operating Revenue

Cafeteria 1,223,945 MEEA Direct 13,617,055 (Amounts received from MEEA, an affiliated organization for services provided.) Overhead received from research 4,750,037 Miscellaneous - and patient care related services 5,029,749 24.620.786 Massachusetts Eye and Ear Infi rmary Form 990 - Schedule A - Part I Expense September 30, 2005 account and Employer I.D. #04-2103591 Fringe Other Compensation Benefits Allowances

Sharon Kujawa Director of Audiology 206,160 39,555 - 243 Charles Street Boston, MA 02114

Bruce Jordan V.P. for Development 185,520 36,154 - 243 Charles Street Boston, MA 02114

M. Charles Liberman, Ph.D Principal Investigator 178,666 35,024 - 243 Charles Street Eaton Peabody Lab Boston, MA 02114

Karen Smith Administrative Officer for Ophthalmology 175,992 34,583 - 243 Charles Street Boston, MA 02114

Kenneth Holmes Chief Financial Officer - MEEA 175,991 34,583 - 243 Charles Street Boston, MA 02114 Massachusetts Eye and Ear Infirmary Form 990 Schedule A, Part III Question 1/Part VI-B-g Employee I.D. #04-2103591 September 30, 2005

During Fiscal Year 2005, the Massachusetts Eye and Ear Infirmary paid a consultant to assist in developing initiatives with respect to public affairs matters relative to healthcare financing, including state appropriations and grants, to assist the Infirmary with developing meetings with the members of the Massachusetts Legislature and Executive Branch, assist in preparing testimony for presentation before all relevant committees of the Massachusetts General Court; develop legislative strategies concerning the initiatives; serve as liaison to government agencies as necessary and monitor and report on government programs relevant to the initiatives.