Int J Endocrinol Metab. 2018 April; 16(2):e13228. doi: 10.5812/ijem.13228. Published online 2018 February 10. Research Article Hypothyroidism and Hypoparathyroidism in Thalassemia Major Patients: A Study in Sistan and Baluchestan Province, Iran Ali Bazi,1 Hadi Harati,2 Ali Khosravi-Bonjar,3 Elham Rakhshani,4 and Mojtaba Delaramnasab1, * 1Clinical Research Development Unit, Amir-Al-Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran 2Professor of Neurology, Amir-Al-Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran 3Faculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, Iran 4Student Research Committee, Zabol University of Medical Sciences, Zabol, Iran *Corresponding author: Mojtaba Delaramnasab, Clinical Research Development Unit, Amir-Al-Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran. Tel: +98-5432232166, E-mail:
[email protected] Received 2017 May 17; Revised 2017 December 10; Accepted 2018 January 03. Abstract Background: Hypothyroidism (HT) and hypoparathyroidism (HPT) are common endocrine complications in thalassemia major (TM) patients. Objectives: In the present study, we assessed the frequency of HT and HPT in a population of TM patients in Southeast of Iran. Methods: This cross sectional study was performed on 194 TM patients in Zabol, Sistan and Baluchestan Province, Iran, during Febru- ary - July 2016. The demographic, clinical, and laboratory data were collected via interviews and history - taking. For hormone mea- surements, specific ELISA kits were used. Statistical analysis was performed in SPSS version 16. Results: A total of 103 (53.1%) and 91 (46.9%) females and males were recruited in this study, respectively. The mean age of the patients was 15 ± 7.5 years.