Headmasters Epigenetic Therapy
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HEADMASTERS THE NEW TEMPLE HEAD & NECK INSTITUTE EPIGENETIC THERAPY A SEA CHANGE FOR CANCER? AGENDA Temple Health Magazine EDITOR Giselle Zayon [email protected] Health Magazine DESIGN & ART DIRECTION B&G Design Studios TWRITERSemple & CONTRIBUTORS HealthMagazine Christopher Guadagnino Rebecca Harmon Eliza Ludwig Meredith Mann Bradley Porter Kara Rogers Ilene Raymond Rush Younndia Rush Jeremy Walter ADMINISTRATION Alan N. Rosenberg, Esq. Senior Vice President/ Doctoring: True to Essence Chief Administrative Ocer Christopher Guadagnino, PhD n May, I will have the privilege of conferring the MD degree on the first group Interim Lead, Communications of medical students I welcomed to Temple when I joined the organization CONTACT US four years ago. I promise you a topnotch medical education, I told them. Oce of Communications I promise you the knowledge and skills befitting the title “doctor.” 3509 N. Broad Street Philadelphia, PA 19140 Over time, I watched this group of students develop into true professionals, 215-707-4839 Iabsorbing concepts and practicing techniques. I also watched some of them struggle. No matter how hard they worked, their faculty — and especially their patients — seemed TempleHealth.org to want something more. 1-800-TEMPLEMED In time, those students recognized what was missing — and then realized that it had Temple University School of Medicine actually been there all along: the very thing that called them to medicine in the first Temple University Hospital place, that innate desire to help and heal. And thus young professionals learn medicine’s Temple University Hospital Episcopal Campus most sacred lesson: patients assume their physicians are competent. But they need to Temple University Hospital know that we care. Northeastern Campus Fox Chase Cancer Center In May, at graduation, I will encourage the Class of 2015 to keep doctoring from this Fox Chase Cancer Center very deep core. It will distinguish every chapter of your career, touch every patient you at Buckingham Fox Chase Cancer Center touch, I will tell them. It’s been the essence of doctoring since ancient times — and will Medical Group remain so, no matter what changes in health care may unfold. Jeanes Hospital Temple Health Oaks Temple Health Center City Temple Health Women’s Care at Elkins Park Temple Health Ft. Washington Temple ReadyCare Temple Physicians, Inc. Temple University Physicians Temple Transport Team Temple Health refers to the health, education, and research activities carried out by the aliates of Temple University Health System, Inc. (TUHS), and Temple University School of Medicine. TUHS neither provides nor controls the provision of health care. All health care is provided by its member Larry R. Kaiser, MD, FACS organizations or independent health care Senior Executive Vice President for Health Sciences, Temple University providers aliated with TUHS member organizations. Each TUHS member Dean & Professor of Surgery, Temple University School of Medicine organization is owned and operated LOBBY: JOSEPH V. LABOLITO; KAISER: DOMINIC EPISCOPO LABOLITO; V. JOSEPH LOBBY: President & CEO, Temple University Health System pursuant to its governing documents. SPRING 2015 | TEMPLE HEALTH MAGAZINE | 1 SPRING 2015 CONTENTS FEATURES 10 Gut Reaction A Full-Service Menu for Overeating-Related Disease BY GISELLE ZAYON 16 Saving Steps On the March to End Amputation BY KARA ROGERS 20 Headmasters The Head & Neck Specialty: A Resident’s Story BY STEVEN ZUNIGA, MD 24 Home Delivery Population Health Programs for At-Risk Patients BY GISELLE ZAYON 28 Epigenetic Therapy A Sea Change for Cancer? BY KARA ROGERS DEPARTMENTS 32 Change Agent Scott Charles: Anti-Gun Violence 34 Quest Marla Wolfson: Liquid Air 36 Tools of the Trade Sewing Lesson: Surgical Needles & Suture 38 Timeline Farewell, “Old Med” 44 So Noted 32 Quips and Counts 45 Artful Ending The Ultimate Selfi e IN EVERY ISSUE 1 Agenda Larry Kaiser, MD, FACS 4 Currents News Roundup 40 Alumni News ON THE COVER: Havoc wrought by chronic overeating, 20 7 28 DREAMSTIME RIGHT: BOTTOM BLOCH; SERGE LEFT: BOTTOM CASTALDI; JARED RIGHT: TOP BLOWERS; DNA: CLINT illustrated by SciePro SPRING 2015 | TEMPLE HEALTH MAGAZINE | 3 EDUCATION & ENGAGEMENT RESEARCH & CLINICAL CURRENTS APPOINTMENTS & ACCOLADES Close to the Far East Expanding its prominence as a collaborative part- ner for medical educa- CURRENTS tion and research in Asia, Temple University School of Medicine has established an aliation with Fu Jen Catholic University School At Your of Medicine in Taiwan. The five-year agreement Service reserves four MD-PhD program slots per year at CONCIERGE SERVICE Temple for Fu Jen students HONORED (who will earn their MD from The concierge service managed Fu Jen and their PhD from by Temple University Physicians Temple), and also features Susan Fisher, PhD is the first Philadelphia health- a medical student exchange care organization to be accepted program for six students at into the National Concierge each institution per year. Association, “a distinction we’re The new aliation fol- honored to receive,” says Lisa Fino, lows in the footsteps of the On Trial Chief Operating Ocer, Temple partnership forged in 2013 University Physicians. Membership, with China’s Jiao Tong Uni- esearch is the linchpin to progress in with industry sponsors, manage regulatory which is reviewed annually, is versity School of Medicine medicine — especially clinical research, compliance processes, and provide services like contingent on maintaining high in Shanghai — an alliance R which moves innovations from the bioinformatics support. standards. “In addition to helping that’s seen much growth and laboratory into testing with real patients. Two make physician appointments activity, including two cross- new initiatives continue to intensify the power BE THE BREAKTHROUGH: Last summer, for our guests, we assist with hotel cultural academic symposia of Temple’s clinical research engine: Fox Chase launched “Be the Breakthrough,” a and travel plans. We even escort held last fall, one at Hong patient-focused campaign designed to increase patients to their physicians’ oces,” Kong Adventist Hospital INSTITUTE ESTABLISHED: “Each step of the awareness of clinical trials for cancer among pa- Fino says. and another in Shanghai at clinical research process — from conceptualiza- tients, caregivers, and families. Since its launch, Jiao Tong University’s Renji tion of an objective to dissemination of study approximately 60 percent more patients have RAPID ACCESS AT Hospital. Both showcased results — must be supported by a system that been enrolled in clinical trials at Fox Chase than FOX CHASE next-generation innovations optimizes eciency, productivity, and quality,” during the previous year. “Clinical trials have the Taking patient-centered respon- that are changing the way says Susan G. Fisher, PhD, Director of the newly potential to result in better treatments and out- siveness to the next level, Fox medicine is practiced in the created Temple Clinical Research Institute. comes” says Evelyn Gonzales, Senior Director of Chase Cancer Center now oers 21st century. Investigators now have ready access to a team Health Communications and Health Disparities. physician appointments to new The Shanghai symposium focused on accelerating the process, with sta Approximately 325 clinical trials are active at patients within 24 hours of their was held in conjunction to coordinate projects, foster partnerships Fox Chase at any given time. first call. “Patients should not have with the 170th anniver- to wait several days to see a cancer sary celebration of China’s specialist,” says Richard Fisher, second-oldest western-style MD, President and CEO of Fox healthcare facility, Renji Chase. Through the Rapid Access Hospital. Hong Kong’s Sec- Dual Roles as CEO Service, new patients are seen retary for Food and Health, within 24 hours of their first call (or Dr. Ko Wing-man, was the Marc Hurowitz, DO, FAAFP, has been named CEO of Jeanes Hospital. on Monday if they call on Friday) — guest speaker of honor, A physician executive with over two decades of leadership experience, even if they don’t have a definitive and Temple’s Larry Kaiser, Hurowitz joined Temple in 2009 and concurrently serves as CEO of diagnosis yet. Since the program MD, FACS, was the only Temple Physicians, Inc., the Health System’s network of community- was launched in March 2014, Fox American medical school based physician practices. At Jeanes, he succeeds Linda Benfield Chase has seen a significant in- dean invited to speak at the Grass, MBA, FACHE, who was CEO for 12 years, and in all devoted three crease in new patient appointments. event, which attracted inter- decades of outstanding service to Jeanes in a variety of positions. ANN CUTTING BURKE DAN FISHER & HUROWITZ: national dignitaries. 4 | TEMPLE HEALTH MAGAZINE | SPRING 2015 SPRING 2015 | TEMPLE HEALTH MAGAZINE | 5 RESEARCH & CLINICAL CURRENTS Lung Update FIRST-EVER GUIDELINES Cancer Notes Last fall, the American College of Chest Physicians SKIN PAIN & ITCH lymph nodes from other parts of a patient’s and the Canadian Thoracic Research led by Gil Yosipovitch, MD, Director body to the a ected area to help drain excess Society released new guide- of the Temple Itch Center, found that itching or lymphatic fl uid. lines for COPD. “Previous pain in a suspicious skin lesion could indicate guidelines addressed man- skin cancer. In his study, published by JAMA RESTAGING CANCER agement of COPD exacerba- Robotic Dermatology, nearly 37 percent of skin