Federal Proposals to Tax Marijuana: an Economic Analysis
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Why Medical Cannabis Is Still out of Patients' Reach—An Essay by David
BMJ 2019;365:l1903 doi: 10.1136/bmj.l1903 (Published 1 May 2019) Page 1 of 3 Feature FEATURE BMJ: first published as 10.1136/bmj.l1903 on 1 May 2019. Downloaded from ESSAY Why medical cannabis is still out of patients’ reach—an essay by David Nutt Cannabis has been used as a medicine for millennia, writes David Nutt, who charts its relatively recent prohibition, the effect on patients such as Billy Caldwell, and the failure of legal reform to make much difference David Nutt Edmond J Safra professor of neuropsychopharmacology Imperial College London, London W12 0NN, UK Cannabis is arguably the world’s oldest medicine, with evidence This report was relied on to control cannabis under the 1961 of such use from 3000 year old tombs in Egypt and Siberia. It United Nations Single Convention on Narcotic Drugs and had a place in Indian and Chinese medical writing from nearly amazingly persisted as the international medical guidance on as long ago. It didn’t enter the UK until the late 1600s, but by cannabis until 2018, being used as the justification by the World the 1800s it was widely used, sold over the counter as an Health Organization for keeping cannabis a schedule 1 http://www.bmj.com/ alcoholic tincture for problems such as tetanus and seizures. Its controlled drug till then. Even more absurdly, the 1934 report efficacy more broadly became apparent, and the definitive has been lost, so we can’t explore its evidential base or overview was published in the Lancet in 1890 by John Russell reasoning.3 1 Reynolds. -
Fuel Properties Comparison
Alternative Fuels Data Center Fuel Properties Comparison Compressed Liquefied Low Sulfur Gasoline/E10 Biodiesel Propane (LPG) Natural Gas Natural Gas Ethanol/E100 Methanol Hydrogen Electricity Diesel (CNG) (LNG) Chemical C4 to C12 and C8 to C25 Methyl esters of C3H8 (majority) CH4 (majority), CH4 same as CNG CH3CH2OH CH3OH H2 N/A Structure [1] Ethanol ≤ to C12 to C22 fatty acids and C4H10 C2H6 and inert with inert gasses 10% (minority) gases <0.5% (a) Fuel Material Crude Oil Crude Oil Fats and oils from A by-product of Underground Underground Corn, grains, or Natural gas, coal, Natural gas, Natural gas, coal, (feedstocks) sources such as petroleum reserves and reserves and agricultural waste or woody biomass methanol, and nuclear, wind, soybeans, waste refining or renewable renewable (cellulose) electrolysis of hydro, solar, and cooking oil, animal natural gas biogas biogas water small percentages fats, and rapeseed processing of geothermal and biomass Gasoline or 1 gal = 1.00 1 gal = 1.12 B100 1 gal = 0.74 GGE 1 lb. = 0.18 GGE 1 lb. = 0.19 GGE 1 gal = 0.67 GGE 1 gal = 0.50 GGE 1 lb. = 0.45 1 kWh = 0.030 Diesel Gallon GGE GGE 1 gal = 1.05 GGE 1 gal = 0.66 DGE 1 lb. = 0.16 DGE 1 lb. = 0.17 DGE 1 gal = 0.59 DGE 1 gal = 0.45 DGE GGE GGE Equivalent 1 gal = 0.88 1 gal = 1.00 1 gal = 0.93 DGE 1 lb. = 0.40 1 kWh = 0.027 (GGE or DGE) DGE DGE B20 DGE DGE 1 gal = 1.11 GGE 1 kg = 1 GGE 1 gal = 0.99 DGE 1 kg = 0.9 DGE Energy 1 gallon of 1 gallon of 1 gallon of B100 1 gallon of 5.66 lb., or 5.37 lb. -
2012-2015 Ryan White Part B Program Comprehensive Plan
2012-2015 Ryan White Part B Program Comprehensive Plan Table of Contents Acronyms ............................................................................................................................... 1 Acknowledgements ................................................................................................................ 5 Introduction ............................................................................................................................ 6 WV Comprehensive Planning Process .......................................................................... 6 Executive Summary ............................................................................................................... 7 1. Where Are We Now: What is our Current System of Care? ................................... 8 HIV/AIDS In West Virginia-Epidemiologic Trends ..................................................... 8 Unmet Need ................................................................................................................. 24 2010 Unmet Need Framework Report ......................................................................... 27 Early Identification of Individuals with HIV/AIDS (EIIHA) ...................................... 43 Prevention Programs .................................................................................................... 49 Partner Services ........................................................................................................... 50 Continuum of Care ...................................................................................................... -
Rethinking America's Illegal Drug Policy
NBER WORKING PAPER SERIES RETHINKING AMERICA'S ILLEGAL DRUG POLICY John J. Donohue III Benjamin Ewing David Peloquin Working Paper 16776 http://www.nber.org/papers/w16776 NATIONAL BUREAU OF ECONOMIC RESEARCH 1050 Massachusetts Avenue Cambridge, MA 02138 February 2011 The authors wish to thank Jonathan Caulkins, Phil Cook, Louis Kaplow, Rob MacCoun, Jeffrey Miron, Peter Reuter, and participants at two NBER conferences and the Harvard Law School Law and Economics workshop for valuable comments. We are also particularly grateful to Jeffrey Miron and Angela Dills for sharing their national time series data on drug prohibition enforcement and crime. The views expressed herein are those of the authors and do not necessarily reflect the views of the National Bureau of Economic Research. © 2011 by John J. Donohue III, Benjamin Ewing, and David Peloquin. All rights reserved. Short sections of text, not to exceed two paragraphs, may be quoted without explicit permission provided that full credit, including © notice, is given to the source. Rethinking America's Illegal Drug Policy John J. Donohue III, Benjamin Ewing, and David Peloquin NBER Working Paper No. 16776 February 2011, Revised March 2011 JEL No. K0 ABSTRACT This paper provides a critical review of the empirical and theoretical literatures on illegal drug policy, including cross-country comparisons, in order to evaluate three drug policy regimes: criminalization, legalization and “depenalization.” Drawing on the experiences of various states, as well as countries such as Portugal and the Netherlands, the paper attempts to identify cost-minimizing policies for marijuana and cocaine by assessing the differing ways in which the various drug regimes would likely change the magnitude and composition of the social costs of each drug. -
Drug Harms in the UK: a Multicriteria Decision Analysis
Articles Drug harms in the UK: a multicriteria decision analysis David J Nutt, Leslie A King, Lawrence D Phillips, on behalf of the Independent Scientifi c Committee on Drugs Summary Background Proper assessment of the harms caused by the misuse of drugs can inform policy makers in health, Published Online policing, and social care. We aimed to apply multicriteria decision analysis (MCDA) modelling to a range of drug November 1, 2010 DOI:10.1016/S0140- harms in the UK. 6736(10)61462-6 See Online/Comment Method Members of the Independent Scientifi c Committee on Drugs, including two invited specialists, met in a DOI:10.1016/S0140- 1-day interactive workshop to score 20 drugs on 16 criteria: nine related to the harms that a drug produces in the 6736(10)62000-4 individual and seven to the harms to others. Drugs were scored out of 100 points, and the criteria were weighted to Neuropsychopharmacology indicate their relative importance. Unit, Imperial College, London, UK (Prof D J Nutt FMedSci); UK Expert Adviser to the European Findings MCDA modelling showed that heroin, crack cocaine, and metamfetamine were the most harmful drugs to Monitoring Centre for Drugs individuals (part scores 34, 37, and 32, respectively), whereas alcohol, heroin, and crack cocaine were the most harmful and Drug Addiction (EMCDDA), to others (46, 21, and 17, respectively). Overall, alcohol was the most harmful drug (overall harm score 72), with Lisbon, Portugal (L A King PhD); heroin (55) and crack cocaine (54) in second and third places. and Department of Management, London School of Economics and Political Interpretation These fi ndings lend support to previous work assessing drug harms, and show how the improved scoring Science, London, UK and weighting approach of MCDA increases the diff erentiation between the most and least harmful drugs. -
Automotive Gasoline Cas # 8006-61-9
AUTOMOTIVE GASOLINE CAS # 8006-61-9 Agency for Toxic Substances and Disease Registry ToxFAQs September 1996 This fact sheet answers the most frequently asked health questions (FAQs) about automobile gasoline. For more information, call the ATSDR Information Center at 1-888-422-8737. This fact sheet is one in a series of summaries about hazardous substances and their health effects. This information is important because this substance may harm you. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. SUMMARY: Exposure to automotive gasoline most likely occurs from breathing its vapor at a service station while filling a car’s fuel tank. At high levels, automotive gasoline is irritating to the lungs when breathed in and irritating to the lining of the stomach when swallowed. Exposure to high levels may also cause harmful effects to the nervous system. Automotive gasoline has been found in at least 23 of the 1,430 National Priorities List sites identified by the Environmental Protection Agency (EPA). What is automotive gasoline? � Other chemicals in gasoline dissolve in water after spills to surface waters or underground storage tank leaks into (Pronounced ô ) the groundwater. 't;-miftlv gasf;-len' The gasoline discussed in this fact sheet is automotive used � In surface releases, most chemicals in gasoline will prob as a fuel for engines in cars. Gasoline is a colorless, pale brown, or ably evaporate; others may dissolve and be carried away by water; a few will probably stick to soil. -
Recognizing Drug Use in Adolescents
RecognizingRecognizingRecognizing DrugDrugDrug UseUseUse ininin AdolescentsAAdolescentsdolescents A Quick Guide for Caregivers and Adults 1 RecognizingRecognizing DrugDrug UseUse inin AdolescentsAdolescents A Quick Guide for Caregivers and Adults Concerned caregivers and adults play an important role in ensuring that youth receive adequate help. However, at times it is hard to tell that youth are developing a problem with alcohol and drugs. This guide summarizes the signs of intoxication, use, and abuse commonly reported by substance users. It is important to recognize, however, that some of the behaviors and experiences described in this booklet may also be present among adolescents who are not using substances. For this reason, when deciding on the best course of action to obtain help for your teenager, make sure to talk with your teenager, gather as much information as possible, and consult with health professionals available in your community. i Alcohol and drug use poses significant risks for the healthy development of adolescents, yet substances of abuse are often readily accessible at school, at home, and in the community. This guide has been developed to facilitate early identification of substance use problems in youth. Included is information about common drugs of abuse and key information to help identify youth at risk. Recognizing the signs of use includes how a teenager might look, act, and feel while intoxicated as well as drug para- phernalia and language associated with each drug. g Signs of intoxication vary by type of -
Mind Medicine Australia’S Submission to the Royal Commission Into Victoria’S Mental Health System
SUB.0002.0029.0347 Mind Medicine Australia’s Submission to The Royal Commission into Victoria’s Mental Health System 5th July 2019 “...My hope is that we will engage in mature, evidence-based discussions about how best to fund and deploy psychedelic-assisted psychotherapies to augment existing approaches to the treatment of mental illness. I hope that governments will have the courage to put the welfare of their citizens ahead of their fear of controversy ‒ and that our politicians will deploy their considerable skills and positions of influence to nurture a balanced and objective understanding amongst the public.” ‒ Dr Simon Longstaff AO, Leading Australian Ethicist and Executive Director of The Ethics Centre Royal Commission into Victoria’s Mental Health System | Mind Medicine Australia SUB.0002.0029.0347_0002 Level 1, 10 Dorcas St Southbank, VIC 3006 Australia 5th July 2019 The Commissioners The Royal Commission into Victoria’s Mental Health System Dear Commissioners We live in one of the wealthiest countries and we have one of the best medical systems in the world. Yet despite the high calibre of our medical practitioners and institutions, and the enormous associated system costs, we also have one of the highest rates of mental illness in the world, and the situation appears to be getting worse. Simply doing more of the same, or making only incremental changes to the current system, is not going to solve this problem and relieve the suffering of so many Victorians. To create positive change, we have to broaden the tools available to our medical practitioners and qualified therapists in this area. -
The Rise and Decline of Cannabis Prohibition the History of Cannabis in the UN Drug Control System and Options for Reform
TRANSNATIONAL I N S T I T U T E THE RISE AND DECLINE OF CANNABIS PROHIBITION THE HISTORY OF CANNABIS IN THE UN DruG CONTROL SYSTEM AND OPTIONS FOR REFORM 3 The Rise and Decline of Cannabis Prohibition Authors Dave Bewley-Taylor Tom Blickman Martin Jelsma Copy editor David Aronson Design Guido Jelsma www.guidojelsma.nl Photo credits Hash Marihuana & Hemp Museum, Amsterdam/ Barcelona Floris Leeuwenberg Pien Metaal UNOG Library/League of Nations Archives UN Photo Printing Jubels, Amsterdam Contact Transnational Institute (TNI) De Wittenstraat 25 1052 AK Amsterdam Netherlands Tel: +31-(0)20-6626608 Fax: +31-(0)20-6757176 [email protected] www.tni.org/drugs www.undrugcontrol.info www.druglawreform.info Global Drug Policy Observatory (GDPO) Research Institute for Arts and Humanities Rooms 201-202 James Callaghan Building Swansea University Financial contributions Singleton Park, Swansea SA2 8PP Tel: +44-(0)1792-604293 This report has been produced with the financial www.swansea.ac.uk/gdpo assistance of the Hash Marihuana & Hemp Museum, twitter: @gdpo_swan Amsterdam/Barcelona, the Open Society Foundations and the Drug Prevention and Information Programme This is an Open Access publication distributed under (DPIP) of the European Union. the terms of the Creative Commons Attribution License The contents of this publication are the sole responsibility (http://creativecommons.org/licenses/by/2.0), which of TNI and GDPO and can under no circumstances be permits unrestricted use, distribution, and reproduction regarded as reflecting the position of the donors. in any medium, provided the original work is properly cited. TNI would appreciate receiving a copy of the text in which this document is used or cited. -
Exploring Inequality
SMU McLane/Armentrout/Bridwell Scholars Reading Groups Fall 2020 Syllabus Exploring Inequality Tues./Wed.: Dean Stansel, Ph.D., Senior Research Fellow [email protected], office: 214-768-3492 Mon./Fri.: Meg Tuszynski, Ph.D., Research Fellow & Assistant Director [email protected], office: 214-768-3170 O’Neil Center for Global Markets & Freedom (www.oneilcenter.org) Cox School of Business, Crow 282 Meeting Times. Our meetings will be held on Mondays (Bridwell), Tuesdays (McLane), and Wednesdays (Armentrout) at 6-7 pm (Central time), and Fridays (Armentrout) at 11am-noon (Central time) online via Zoom. All four groups have the same readings. Attendance is required. Your attendance and active participation are required. We will have 10 regular meetings plus a joint reading group summit with the students from similar reading groups at Baylor, Texas Tech, Angelo State, and University of Central Arkansas. That event will be held online via Zoom on the morning of Sat. Oct. 17 and is a required part of the program. You will not be paid the $1000 stipend if you do not attend. You are required to attend all 10 weekly meetings. However, if you have an unavoidable conflict, we do have limited flexibility, with advance notice, for you to switch nights if you cannot attend on your regular reading group night (i.e., if you can’t make one of your regular Monday night meetings, you can instead attend on Tuesday, Wednesday, or Friday that week and vice-versa). In addition, the O’Neil Center hosts several guest speakers throughout the semester. Those will all be online this semester. -
Estimates of Nitrous Oxide Emissions from Motor Vehicles and the Effects of Catalyst Composition and Aging
ESTIMATES OF NITROUS OXIDE EMISSIONS FROM MOTOR VEHICLES AND THE EFFECTS OF CATALYST COMPOSITION AND AGING Contract No. 02-313 STATE OF CALIFORNIA AIR RESOURCES BOARD Final Report Prepared by Arthur M. Winer, Ph.D. Principal Investigator Environmental Health Sciences Department and Environmental Science and Engineering Program School of Public Health University of California, Los Angeles, California, 90095 (310) 206-1278 Eduardo Behrentz, D.Env. Co-Investigator Environmental Science and Engineering Program School of Public Health University of California, Los Angeles June 10, 2005 N2O Emissions from Motor Vehicles DISCLAIMER The statements and conclusions in this report are those of the contractor and not necessarily those of the California Air Resources Board. The mention of commercial products, their source, or their use in connection with material reported herein is not to be constructed as actual or implied endorsement of such products. i N2O Emissions from Motor Vehicles ii N2O Emissions from Motor Vehicles ACKNOWLEDGEMENTS The contributions of the California Air Resources Board staff, particularly Paul Rieger, who made invaluable suggestions and contributions throughout the project, and Hector Maldonado who acted as our Project Officer, were greatly appreciated. We also thank Richard Ling of the Monitoring and Laboratory Division who collected all emissions data from the 16th Vehicle Surveillance Program and who provided on-site training and support. We thank Margo Eaddy for her participation during the data collection process. We wish to acknowledge valuable contributions from Jerry Ho and Robin Lang of the Mobile Source Operations Division who provided logistical support during vehicle testing and data collection. We especially appreciated Shane Michael, the project’s Test Engineer, of the Mobile Source Operations Division for his professionalism and willingness to assist us throughout the study. -
Volatile Solvents As Drugs of Abuse: Focus on the Cortico-Mesolimbic Circuitry
Neuropsychopharmacology (2013) 38, 2555–2567 & 2013 American College of Neuropsychopharmacology. All rights reserved 0893-133X/13 www.neuropsychopharmacology.org Review Volatile Solvents as Drugs of Abuse: Focus on the Cortico-Mesolimbic Circuitry 1,2 ,1,2 Jacob T Beckley and John J Woodward* 1 2 Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA; Center for Drug and Alcohol Programs, Department of Psychiatry/Neurosciences, Medical University of South Carolina, Charleston, SC, USA Volatile solvents such as those found in fuels, paints, and thinners are found throughout the world and are used in a variety of industrial applications. However, these compounds are also often intentionally inhaled at high concentrations to produce intoxication. While solvent use has been recognized as a potential drug problem for many years, research on the sites and mechanisms of action of these compounds lags behind that of other drugs of abuse. In this review, we first discuss the epidemiology of voluntary solvent use throughout the world and then consider what is known about their basic pharmacology and how this may explain their use as drugs of abuse. We next present data from preclinical and clinical studies indicating that these substances induce common addiction sequelae such as dependence, withdrawal, and cognitive impairments. We describe how toluene, the most commonly studied psychoactive volatile solvent, alters synaptic transmission in key brain circuits such as the mesolimbic dopamine system and medial prefrontal cortex (mPFC) that are thought to underlie addiction pathology. Finally, we make the case that activity in mPFC circuits is a critical regulator of the mesolimbic dopamine system’s ability to respond to volatile solvents like toluene.