WARS Antibody Cat. No.: 27-187

WARS Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human WARS.

TESTED APPLICATIONS: ELISA, WB

WARS antibody can be used for detection of WARS by ELISA at 1:62500. WARS antibody APPLICATIONS: can be used for detection of WARS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

PREDICTED MOLECULAR 52 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

September 28, 2021 1 https://www.prosci-inc.com/wars-antibody-27-187.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store WARS STORAGE CONDITIONS: antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: WARS

ALTERNATE NAMES: WARS, GAMMA-2, IFI53, IFP53

ACCESSION NO.: NP_004175

PROTEIN GI NO.: 47419914

GENE ID: 7453

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate . Because of their central role in linking amino acids with triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by . Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by BACKGROUND: their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this .

REFERENCES: 1) Shen, N., (2008) Nucleic Acids Res. 36 (4), 1288-1299.

ANTIBODIES FOR RESEARCH USE ONLY.

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