Primary Cutaneous Adenoid Cystic Carcinoma: a Case Report and Review of the Literature
Primary Cutaneous Adenoid Cystic Carcinoma: A Case Report and Review of the Literature Jennifer Barnes, MD; Carlos Garcia, MD Primary cutaneous adenoid cystic carcinoma is x-ray were normal. Serum carcinoembryonic antigen a rare cancer, with only 61 cases reported in levels were within reference range. The lesion was the literature. We report an additional case and treated with Mohs micrographic surgery and tumor- review the latest recommendations for workup free margins were achieved in 2 stages. The defect and treatment. was repaired with a rotation flap. The patient was Cutis. 2008;81:243-246. recurrence free at 6-month follow-up. Comment Adenoid cystic carcinoma can arise from a vari- Case Report ety of primary sites, including the salivary glands, A 62-year-old woman presented to her dermatolo- respiratory tract, cervix, vulva, breast, thymus, gist with several months’ history of a painless nodule prostate, external auditory canal, esophagus, and on the scalp. The patient had a prior medical his- skin.1,2 Adenoid cystic carcinoma most commonly tory of hypertension and osteoporosis. Results of a presents in the major and minor salivary glands, physical examination revealed a hard, 20311-mm, so primary adenoid cystic carcinoma of the major pink and flesh-colored lesion in the mid- and minor salivary glands must be ruled out. In line parietal region of the scalp with alopecia general, adenoid cystic carcinoma can have late- over the nodule (Figure 1). Results of a shave occurring metastasis, involving regional nodes, biopsy stained with hematoxylin and eosin was lungs, bone, and brain, but cutaneous metastasis diagnostic of primary cutaneous adenoid cystic from a primary head and neck adenoid cystic car- carcinoma (Figure 2).
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