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From Eureka to Your World : Headway 2015-06-24, 11:39 AM From Eureka to Your World : headway 2015-06-24, 11:39 AM McGill Publications headway Research, discovery and innovation at McGill University Wednesday, June 24th, 2015 | Français News feed Search this website... GO Home Magazine About Research Funding Sources Multimedia Archives Sections Act Locally/Act Globally Cover Story First Person In Depth/In Focus Industrial Impact Making Headway Multimedia Networks Neuroscience New Wave News Bites Research Focus Special Report Vice-Principal's message Workspace Home > Articles > Volume 4, Number 1 > From Eureka to Your World Cover Story http://publications.mcgill.ca/headway/magazine/from-eureka-to-your-world/ Page 1 of 20 From Eureka to Your World : headway 2015-06-24, 11:39 AM From Eureka to Your World Volume 4, Number 1 Share this By Jake Brennan, Danielle Buch, Thierry Harris and Andrew Mullins; illustrations by Matt Forsythe 33 Ways* That McGill Research Saves Lives, Kills Weeds, Nabs Thieves… and More * (and counting) In the world of McGill research, creating new knowledge isn’t an end—it’s the means for developing the innovations that change our world. Lives are improved, and even saved, by ideas that make the long journey from lab to marketplace. And, yes, the commercialization of research stimulates our economy at the local, provincial, national and international levels. We’ve collected just some of the ways McGill research has improved and is improving quality of life, from time-tested “greatest hits” to up-and-comers tipped to revolutionize tomorrow’s world—each a concrete manifestation of the University’s mission of “…providing service to society in those ways for which we are well suited by virtue of our academic strengths.” 1. Developing new drugs “on the ground”—and using local resources—is critical to fighting parasitic diseases in African countries. Timothy Geary, the Canada Research Chair in Parasite Biotechnology, and Eliane Ubalijoro of McGill’s Institute for the Study of International Development are using a $100,000 grant from the Bill and Melinda Gates Foundation to establish anti-parasitic drug development programs that draw upon existing resources in Botswana, South Africa and other http://publications.mcgill.ca/headway/magazine/from-eureka-to-your-world/ Page 2 of 20 From Eureka to Your World : headway 2015-06-24, 11:39 AM countries in Africa. By promoting a simple technology for drug discovery, which uses microbes genetically engineered to express parasite proteins, researchers can easily test for the presence of anti- parasitic agents derived from indigenous botanical sources. This system can provide a sustainable way for African scientists to control the fate of locally obtained compounds, rather than relying on imported Western technologies (which, history has shown, are prohibitively difficult to maintain in working order) or agreements that favour Western partners unnecessarily. The ultimate goal is to empower African researchers to develop, market or out-license new, affordable cures for locally important parasitic infections, such as river blindness or lymphatic filariasis, which affect hundreds of millions of people, and malaria, which kills a million people (mostly children) a year in tropical countries. 2. If diagnosed with chronic obstructive pulmonary disease—the fourth leading cause of death in Canada —often the only thing your doctor can do to slow the fatal incurable disease is tell you to stop smoking. Now, work produced in McGill’s Department of Chemistry by Masad J. Damha might be able to reverse the effects of chronic obstructive pulmonary disease. By modifying the structure of nucleic acids through chemical alterations of the sugar unit of the oligonucleotide chain, Damha’s research makes it possible to “shut down” critical genes that cause inflammation in the lungs. Damha and collaborators founded Anagenis Inc. in 1999 to exploit the powerful properties of these oligonucleotides. Topigen Pharmaceuticals, a company specializing in respiratory disorders, acquired Anagenis Inc. and the team’s gene silencing technology in 2004. Clinical development is projected in 2009. 3. If you like Miles Davis, you’ll love… Kanye West? McGill psychology professor Daniel Levitin, with Yoshua Bengio and Douglas Eck from the Université de Montréal and Robert Gérin-Lajoie of the CIRANO interuniversity research centre, have developed software that can predict what songs listeners will like, based on a listener’s past preferences and personal information. According to the International Federation of the Phonographic Industry, some 1.4 billion songs were legally downloaded internationally in 2008; this new software, dubbed Shazam (not to be confused with the iPhone application of the same name), may help even more music fans find the sounds they like—even ones they haven’t yet heard. Amazon, Microsoft and Apple offer similar recommendation software, but Shazam is different because it extracts intelligent information, such as tempo, genre and mood, directly from songs. The researchers created the software using a database of over 100,000 songs donated by Warner Bros. The technology was licensed to Double V3, a developer of Internet and digital media http://publications.mcgill.ca/headway/magazine/from-eureka-to-your-world/ Page 3 of 20 From Eureka to Your World : headway 2015-06-24, 11:39 AM applications, and is now owned by Nexio and Zanura. 4. McGill psychology professor Mark Baldwin and his graduate students have tapped into the ever- evolving video game market with a series of self-esteem boosting video games called Mindhabits. The games, which are sold online and in stores (they’re particularly popular in European markets), help people by working on the psychological principles of association, inhibition and activation. In one game, players search for words related to friendship (drawing on the wealth of research showing that even small reminders of camaraderie help people deal with stress better); in another, they practice disengaging from unhelpful thoughts of social threat by clicking on smiling faces and ignoring frowns. A study published in a journal of the American Psychological Association demonstrated that just five minutes of daily play reduced players’ stress hormone levels by 17 per cent. Mindhabits also permits players to measure and track their confidence and stress levels on a day-to-day basis. In 2007, the games won the $1.3-million first prize in Telefilm’s Great Canadian Video Game competition; the prize money is being used to develop the game for play on several different game platforms. Mindhabits is expected to be available on Nintendo DS and mobile platforms later this year. 5. Build a more economical anti-theft tag, and the world—or at least its stores and libraries—will beat a path to your door. Security tags or labels all have two components: an active element (that’s the part that triggers alarms) and an element that turns off the active element. By combining electroplating technology with a specially formatted stainless-steel wire, McGill emeritus physics professor John Ström-Olsen and his company MXT have been able for the first time to integrate the active and deactivating components into a single element—making tags cheaper, and easier, to manufacture. The SSDW anti-theft tag, a happy accident stemming from an earlier product development that didn’t quite pan out, can be produced for about 60 per cent of the cost of other tags. SSDW came onto the market in 2005, and has already achieved significant, and growing, market penetration in Europe, North America and Asia. http://publications.mcgill.ca/headway/magazine/from-eureka-to-your-world/ Page 4 of 20 From Eureka to Your World : headway 2015-06-24, 11:39 AM 6. For marine researchers, wetlands, coral reefs, swamps and shallow coastlines can be difficult to access —especially when you don’t want to upset the wildlife. The Aqua project, a collaboration between engineerting professor Greg Dudek and researchers at McGill’s Centre for Intelligent Machines, McGill biology professor Donald Kramer and his grad student Katrine Turgeon, and Michael Jenkin of York University, aims to change this by inventing three models of amphibious, video-data- gathering robots. The fully autonomous robots use six independently controlled flippers and acoustic sensor technology to gently navigate through waters deep or shallow. The robots are commercially available from Independent Robotics Inc. 7. As electronic components in computers get smaller, smarter and greener, so grows hardware manufacturers’ need to assess potential uses of different nano-materials. The research group of McGill physics professor Hong Guo has developed a software program that they think will help. Using density functional theory and quantum transport theory, the software simulates the electrical properties of nano-structures, then models their performance in would-be large-scale systems, thus simulating computer transistor (as well as sensor- and photo-cell) performance. The use of such software is expected to help reduce the cost of manufacturing prototypes. McGill IP related to this software has been licensed to a Quebec start-up for commercial development. 8. The interactive web-based literacy tool Abracadabra has the potential to dramatically improve literacy across Canada. For children and parents, Abracadabra offers fun and engaging games and exercises in reading, spelling, vocabulary and comprehension. For educators, it offers resources such as manuals and literacy skills assessments to help target learning appropriately. Unlike other online literacy tools, Abracadabra is publicly available and free. McGill education professor and literacy expert Robert Savage designed the research behind Abracadabra. The project was directed by Philip Abrami from the Centre for the Study of Learning and Performance at Concordia University, and http://publications.mcgill.ca/headway/magazine/from-eureka-to-your-world/ Page 5 of 20 From Eureka to Your World : headway 2015-06-24, 11:39 AM included researchers from Wilfrid Laurier University and the University of Lethbridge. Abracadabra is in use all over the world, and the team is now building a similar tool for developing writing skills.
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