Impact Review 2018-19 Turning possibilities into better healthcare Contents

About us 3

Foreword 4

Message from our Executive Director 5

Building our strategic partnerships 6-7

Enhancing the Cambridge life sciences narrative 8-9

Integrating data for care and research 10-11

Delivering multi-professional education 12-13

Developing the Cambridge Biomedical Campus 14-15

Looking forwards: Our programme approach 16-17

Our year in colour 18

Working in Partnership with

Cambridgeshire and Peterborough NHS Foundation Trust Cambridge University Hospitals NHS Foundation Trust Royal Papworth Hospital NHS Foundation Trust

Annual Impact Review 2018-19 2 About us

Cambridge University Health Partners (CUHP) is one of six Academic Health Science Centres in England whose aim is to improve patient healthcare by bringing together the NHS, industry and academia. “Our mission is to improve local and global health by effective alignment of our world-class assets”

Academic Health Science Centres (AHSCs) were launched by the Department of Health in 2009 as it looked to identify outstanding partnerships between leading NHS Trusts and universities. Six centres in total have been created in: Cambridge, (Imperial College, King’s College and University College London), Manchester and Oxford. They were chosen owing to their strong convergence of university research and education, research institutes, clinical services and the life sciences industry. They are key to innovation in the diagnosis and treatment of patients but also the growth of pharma, biotech and healthtech companies in the UK. Based on the Cambridge Biomedical Campus, CUHP was set up as a Company Limited by Guarantee in 2009. The CUHP Partners are Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge University Hospitals NHS Foundation Trust, Royal Papworth Hospital NHS Foundation Trust and the University of Cambridge.

3 Foreword

I joined Cambridge We have welcomed Abcam to the campus and and development opportunities available to University Health look forward to AstraZeneca joining us soon. improve patient outcomes – including those Partners (CUHP) in The growing numbers of campus organisations arising from the Life Sciences Industrial Strategy. February 2018 at a provide us with even more exciting opportunities Our first Impact Review highlights that we are pivotal time for our four for collaboration between industry scientists, making good progress but we are certainly not partner organisations, university researchers and clinicians. In tandem, complacent. There is more to do. Although there the Cambridge we recognise that a single organisational outlook are challenges to address, we are confident Biomedical Campus – and governance structure for the campus is that the engagement and expertise of our four and for the UK itself. needed and look forward to supporting its partners will support the development of an creation. This alignment will provide many Each CUHP partner has achieved significant effective integrated research, health and care benefits including a stronger proposition for life milestones over the last year. Royal Papworth system – with corresponding benefits for staff, science companies and planning authorities. Hospital has completed a seamless transition to patients and the public. the Cambridge Biomedical Campus, occupying We have worked closely with the CUHP a new state-of-the-art clinical facility, while Board members to strengthen local, regional Laurel Powers-Freeling Cambridge University Hospitals, Cambridgeshire and national partnerships, striving to build Chair and Peterborough NHS Foundation Trust and the an attractive community on and around the University of Cambridge have made substantial campus, as well as establishing links with the progress in securing funding for a Children’s wider Cambridge cluster. At the same time, Research Hospital in the East of England. CUHP has sought to maximise the innovation

Annual Impact Review 2018-19 4 Message from our Executive Director

The context for A joint programme in health informatics with Raising the profile of Cambridge life sciences each Academic the Eastern Academic Health Science Network to UK Government, researchers, industry, Health Science has allowed us to make a strong contribution investors and philanthropists remains a key Centre is unique. In to regional efforts to integrate the local health part of our work. Working with our partners, this, our first Impact and care record, in parallel with development we have continued to showcase the positive Review, we take the of novel data science approaches. In particular, contribution that our sector is making to the opportunity in collaboration with five UK NHS Trusts and UK economy and to identify new opportunities to articulate our the private sector, the team were awarded a which could deliver even greater success. strengths and £400,000 Sprint Exemplar Innovation Project. Looking forward to 2019-20, our new CUHP progress during 2018-19 and to outline our Coordinated by Health Data Research UK programme approach will bring our central priorities and areas of focus for the year ahead. and funded through the UK Research and team together with the focused expertise of our Innovation Industrial Strategy Challenge fund, CUHP is strongly committed to growing Board members to deliver new projects across this project in rare diseases will demonstrate a remarkable combination of world class our portfolio in Ecosystem Development, data liquidity through development of a secure assets – health, science and industrial – on Education, Governance, Health Informatics and cloud research platform. the Cambridge Biomedical Campus, and to Innovation and Implementation. By fostering forging a wider set of partnerships, networks CUHP continues to collaborate with a range of closer collaboration, we will continue to and alliances to realise new opportunities for external partners to deliver multi-professional identify new opportunities and partnerships improved patient outcomes. education activities which develop workforce which could not be realised by a single partner capabilities clearly articulated within the NHS and which improve local and global health by This year, we were excited to develop and sign Long Term Plan. In particular, our leadership effective alignment of our world-class assets. separate Memoranda of Understanding with programmes have supported over 220 the Association of British HealthTech Industries senior leaders this year, and a novel Masters Malcolm Lowe-Lauri (ABHI) and Roche Products to extend our reach in Health Data – Analytics, Innovation and and to accelerate the discovery, development Executive Director Commercialisation will start in September. and delivery of innovative health and care solutions.

5 Building our strategic partnerships

CUHP is strongly committed to a wider set of CUHP maintains strong working links to the An exciting new partnership with Roche partnerships, networks and alliances which Office for Translational Research, based within Products will further our joint commitment will enhance the community on the Cambridge the University School of Clinical , to improving patient outcomes through Biomedical Campus (CBC), encourage and the Cambridge University Development personalised healthcare. Projects will focus on closer collaborative working between our and Alumni Relations office. CUHP also has the development of breakthrough organisations and accelerate the translation of strong relationships with the NIHR Biomedical and leading diagnostics, and how these innovation into routine clinical practice. Research Centre and the NIHR Collaboration for might be combined with new reimbursement Leadership in Applied Health Research and Care models to realise greater value for patients Recognising a shared interest in developing the (CLAHRC) East of England. and healthcare providers. We look forward CBC as an internationally recognised centre of to exploring new approaches to value-based excellence, CUHP partners with Countryside Our partnership with the Eastern Academic healthcare with Roche, focused initially on Properties and Liberty Property Trust, the Health Science Network strengthens our links particular clinical pathways. developers of the commercial quarter of with research-active organisations across the the CBC. In this capacity, we work to attract region, further accelerating the adoption and “CUHP has enhanced our understanding organisations to the campus in line with our spread of innovation. Joint projects focus on of the best ways to work with our NHS strategic foci, allowing us to play an active role healthtech, identifying technological solutions partners. It has enabled us to identify in growing a remarkable combination of health, to improve mental health and to support healthy shared priorities around improving patient science and industrial assets. ageing, together with a comprehensive health care. This is an important step in helping informatics programme to improve our regional Roche to create long-lasting and effective infrastructure for clinical service and health partnerships that will ultimately bring data research. true value both to the NHS and the life In 2018-19, we have agreed two new strategic sciences industry.” partnerships which will extend the reach of Karen Lightning-Jones CUHP and our partners at a national level: Head of Future Place: Strategic Partnerships and Personalised Healthcare Roche Products

Annual Impact Review 2018-19 6 To support our strategic focus on medical We are proud to be part of CUHP. At technology, CUHP will partner with the Association of British HealthTech Industries Royal Papworth Hospital, we are focused (ABHI), the UK’s leading industry association on delivering outstanding patient care as for health technology, representing over 300 member firms who support healthcare delivery. an innovative and pioneering institution. Working in partnership across the Eastern We know to develop the treatments of region, we will encourage inward investment from the healthtech industry, enhancing the the future requires collaboration with value that health technology investment brings industry, research and clinicians. to health and social care and supporting regional economic development. CUHP have therefore been pivotal in our “ABHI was delighted to sign a efforts to establish relationships with the Memorandum of Understanding with commercial sector, from connecting the CUHP. Along with Birmingham, Leeds and Manchester this allows us to develop a Trust with Philips to the development formidable grouping for the healthtech side of the CBC Heart and Lung Research of the UK Life Sciences industry. We look forward to turning that into breakthroughs Strategy. Now we have moved to the for patients and business in the UK.” campus, these opportunities can only Richard Phillips grow and it is an exciting time for us all.” Director, Healthcare Policy Association of British HealthTech Industries Stephen Posey (ABHI) Chief Executive, Royal Papworth Hospital NHS Foundation Trust (RPH)

7 Enhancing the Cambridge life sciences narrative

Working closely with our partners, CUHP In January 2019, our flagship event convened continues to refine and communicate over 100 delegates from the Cambridge a compelling vision of the Cambridge cluster and the wider UK life sciences Biomedical Campus as part of the wider sector. Keynote speakers, including Charlie Cambridge life sciences cluster. Davie, Managing Director of UCLPartners, highlighted new and effective models for To underline this, we have worked closely industry-NHS partnering, while a panel of with local authorities and the Department representatives from CUHP, IBM, Roche for International Trade to support inward and the PHG Foundation were challenged investment. In 2018-19, CUHP hosted 26 to consider how the NHS could work more events with over 900 attendees, including effectively with industry and researchers to representatives from 24 countries and over deliver the treatments that will transform 120 international companies. future healthcare. In May 2018, we partnered with Eastern The Cambridge Science Festival attracts Academic Health Science Network (AHSN) to more than 30,000 visitors to over 250 bring together over 120 academics, clinicians events across the city – including many on and industry partners in medical technology the CBC. In support of this year’s event, the from 78 regional organisations. A series of CUHP team operated a CBC stand to inform keynotes and roundtable discussions allowed interested public on the latest campus delegates to share experiences at the cutting developments and organised guided tours edge of medtech development, highlighting for 360 people to visit the Addenbrooke’s perspectives from large multi-nationals and Mortuary and Transplant Theatre and the SMEs and catalysing new collaborations. newly opened Royal Papworth Hospital – all of which received excellent feedback from the general public.

Annual Impact Review 2018-19 8 At a local level, CUHP has also led the CUHP has played a central role in development of a quarterly CBC supplement with the Cambridge Independent, an initiative the development of the Cambridge which is jointly contributed to and funded Biomedical Campus, one of the biggest by organisations across the campus. The publication reaches a circulation of 10,000 research centres in Europe, fostering people in the local area to highlight the ways collaboration between University in which people on the site improve health and care through research and innovation. researchers, industrial partners and three We have also supported national stakeholder highly respected NHS Trusts. It holds engagement, creating greater awareness of our world class capabilities and maximising tremendous opportunities for industrial opportunities for the region arising from the Life strategy and clinical innovation and we Sciences Industrial Strategy. As such, in February 2019, we were pleased to host representatives are proud of the contribution it continues from the Office for Life Sciences on behalf of our to make nationally and internationally.” partners, showcasing the positive contribution that our region is making to the UK economy Professor Andy Neely while also highlighting new opportunities for Pro-Vice-Chancellor for Enterprise and sector growth. Business Relations, University of Cambridge

9 Integrating data for care and research

This year, CUHP initiated a joint programme in supporting the identification, diagnosis and We are also developing individual strategic health informatics with the Eastern Academic treatment of the one in 17 people in the UK who partnerships in health informatics on the Health Science Network (AHSN), have a rare disease. Working with five NHS Trusts, Cambridge Biomedical Campus as well as focussing on data integration for both direct Eastern AHSN and private sector partners, exploring the development of ‘narrow & deep’ care and research. the HDR UK Rare Diseases Sprint Exemplar data resources for research, for example Innovation Project has made significant opportunities to integrate digital imaging, Direct care initiatives include developing a progress in developing a secure cloud research pathology data for machine learning and specification and funding proposal for a local platform with the potential to transform the artificial intelligence. Cambridgeshire and Peterborough Sustainability understanding of rare genetic disorders, drive and Transformation Partnership (STP) integrated CUHP has also provided support to local improvements in diagnosis and provide proof of care record, and support to the programme education and training programmes in health principle for use in other diseases. leading on creating a local integrated health and informatics. care record to link local initiatives across the six CUHP is currently working with Eastern AHSN, STPs in the Eastern region. Cambridge University Hospitals and the NIHR BioResource to coordinate the development CUHP was instrumental in helping to win of a much larger bid to develop a Digital a £400,000 grant, coordinated by Health Innovation Hub, with an initial focus on Data Research (HDR) UK and funded by the Inflammatory Bowel Diseases across more than UKRI Industrial Strategy Fund, with the aim of 90 hospitals in the UK.

Annual Impact Review 2018-19 10 Eastern AHSN has enjoyed working more closely with CUHP over the last year. Of particular note is the appointment of Mark Avery as Director of Health Informatics across our two organisations. Mark’s work has made a real contribution to the early stages of developing a shared health and care record across our region and has also resulted in a grant from HDR UK to develop a ground-breaking use of different data sets in three rare diseases.

Piers Ricketts Chief Executive, Eastern AHSN

11 Delivering multi-professional education

CUHP collaborates with a range of external School and Cambridge University Hospitals Clinical Programmes partners to deliver multi-professional education (CUH) Postgraduate Medical Centre, supported There has been a hugely positive response to activities which develop our workforce by Health Education England (HEE) – East of the new Masters in Health Data – Analytics, capabilities. England. Innovation and Commercialisation. Starting in September 2019, this programme has leveraged Our educational strategy is based on three Four cohorts have completed the Learning to over £440,000 in funds with over 50 applicants themes: Lead programme, with a fifth starting in June for approximately 15 places. 2019. Excellent feedback was received from • Development of leadership capacity both attendees on the first regional Medical Trainee Twenty-one students are enrolled on the locally and in the wider health economy. Leadership Development Programme. present PGCert in Healthcare Research, • Specialist educational programmes that Education and Leadership course, with plans provide excellence in healthcare education The first cohort of the CUH Senior Leadership to deliver the next course in Autumn 2019 and spanning a range of healthcare professions. Development Programme successfully develop this into a Masters programme in 2020. completed the course. Two further cohorts are • Technology enhanced learning planned and further leadership programmes A successful Cambridge Trauma Conference methodologies and facilities. are being developed to run from Autumn 2019, was held in April 2018, with excellent feedback Leadership Courses including Leading for Excellence. from a multi-professional audience. A CUHP Diabetes programme in primary care is also Over the past year, CUHP leadership ‘This was a very good course and I would underway, supported by £170,000 from HEE. development programmes have supported highly recommend it to trainees in all over 220 senior leaders. specialities. The concepts covered in Technology Enhanced Learning Successful courses include the Chief Resident the course were relevant and thought Over 200 days of technology enhanced learning Clinical Leadership and Management provoking to current clinical practice.’ have been delivered by CUHP via The Evelyn Cambridge Surgical Training Centre and The Development Programme, developing Delegate leadership and management skills of 60 Cambridge Simulation Centre, to a combined Medical Trainee Leadership Development senior trainees within the region every year. total of over 1,000 delegates. In the last year, Programme This is a joint initiative now in its eighth year Royal College of Surgeons accreditation between The Cambridge Judge Business for these centres has also been secured. A £200,000 grant from HEE has been approved to deliver the East of England cadaveric training programme and £110,000 funding from HEE has been awarded to deliver the East of England Simulation programme.

Annual Impact Review 2018-19 12 The role that CUHP plays in bringing together partners from the NHS, industry and academia is crucial to the delivery of the CUH strategy, particularly in improving patient journeys, developing our workforce and contributing on a national and international stage. Underpinned by the collective strength of the four partners, CUHP provides a hugely powerful voice for health, care, research and education on the Cambridge Biomedical Campus, and helps to make it an attractive place for further partners to base their operations.”

Roland Sinker Chief Executive, Cambridge University Hospitals NHS Foundation Trust (CUH)

13 Developing the Cambridge Biomedical Campus

Campus Expansion This approach will ensure we continue to attract Communications The Cambridge Biomedical Campus (CBC) a highly skilled workforce to the campus as well The Communications Group brings together is located at the heart of the UK’s leading as new organisations that share our vision. the diverse organisations across the campus to life sciences cluster, a unique environment In support of these aims, CUHP convenes share information, develop site wide campaigns combining world-leading academic clinicians several operational groups across the CBC and work together to highlight the amazing and industry scientists. Working in partnership where all campus partners are represented in key things which happen at the CBC. A key success with Countryside Properties and Liberty Property areas: Amenities, Communications and Travel in the past year has been the development of a Trust, CUHP have helped to refine plans and a & Transport. Throughout 2018-19 these groups quarterly CBC supplement with the Cambridge pre-commercial marketing strategy for both have worked to future-proof the campus while Independent. This publication is jointly single and multi-occupancy development also linking to independent CBC groups such as contributed to and funded by organisations opportunities on Phase 2 – anchored by the new Security & Resilience, and Health & Safety. across the campus and reaches a circulation of Abcam headquarters which opened in February 10,000 people in the local area to highlight the 2019. By accommodating start-ups and SMEs Amenities impact which people on the site are making to alongside larger scale-ups and multi-nationals The Amenities Group has successfully change lives through research and healthcare. as part of the CBC expansion, we aim to further developed, undertaken and analysed a survey diversify the life sciences community on the on demand for nursery provision, developed Tony Taylorson campus and to attract new organisations which an agreed set of principles relating to smoking Communications Manager, Cambridge enhance the translational lifecycle at every stage. across the campus and provided joint responses University Health Partners to external bodies regarding requirements for Promoting supportive infrastructure Chair, CBC Communications Group social housing in South Cambridgeshire. The The CBC is the largest employment site in group is also exploring the provision of food Cambridge, with 26,500 visits to the campus and beverages across the campus as well as the every day from patients, clinical staff, scientists appropriate use and management of and visitors. Besides expansion, CUHP work to shared spaces. enhance the campus for our existing community while engaging with external partners to develop John Syson supportive infrastructure. Deputy Director of Workforce and Organisational Development, Royal Papworth NHS Foundation Trust Chair, CBC Amenities Group

Annual Impact Review 2018-19 14 Travel and Transport We work together with CUHP to attract new investment and The Travel and Transport Group has agreed innovation which can draw on the benefits the campus offers for its CBC Transport Strategy and 5-Year Implementation Plan and has made good collaboration between academics, business and clinicians. headway in delivering this – bringing campus organisations together collectively to deliver To date, over 2.0 million sq ft has been committed for improved travel choices which minimise development to occupiers including AstraZeneca, Abcam and motorised traffic. Key successes include work with transport operators for better bus services the MRC Laboratory of Molecular Biology. – such as the implementation of the ‘H’ bus (Papworth and Cambourne route) – plus The year ahead will see us continuing to work together to funding approval for a campus-wide site safety attract occupiers to the campus in line with CUHP’s strategic audit and infrastructure masterplan refresh. priorities and to develop the CBC into an internationally recognised Rachel Northfield centre of excellence”. Estates and Facilities, Head of Quality and Safety Governance, Cambridge University Hospitals Andrew Carrington Andrew Blevins NHS Foundation Trust Managing Director, Managing Director, Chair, CBC Travel and Transport Group Countryside Properties – Strategic Land Liberty Property Trust UK Ltd

15 Looking forwards: Our programme approach

CUHP is taking a new approach which shortages and training requirements, the health data research and innovation. The group concentrates its activities into five programme provision of education facilities on the CBC, will also facilitate development of integrated groups, bringing our central team together and new opportunities, particularly in real world patient data sets in partnership with with the focused expertise of our Board technology enhanced learning, which arise Cambridgeshire and Peterborough STP and the members to deliver outcomes from a series from the NHS Long Term Plan. Eastern AHSN. of new projects: Governance Innovation and Implementation Ecosystem development Chaired by Laurel Powers-Freeling, Chaired by Professor Peter Jones, Director Chaired by Professor Andy Neely, Pro-Vice- Businesswoman and Chair, Cambridge NIHR Collaboration for Leadership in Applied Chancellor, Enterprise and Business Relations, University Health Partners Research and Care (CLAHRC) East of England University of Cambridge Recognising the opportunities and the Featuring close partner working with At a local level, the group will strengthen constraints of the multi-partner CBC, the group Cambridgeshire and Peterborough NHS entrepreneurship and business development will lay the groundwork for creation of a single Foundation Trust, NIHR CLAHRC East of activities on the Cambridge Biomedical organisational approach. This challenging goal England, Eastern AHSN and Roche, projects Campus (CBC) to develop a vibrant innovation has arisen directly in response to consultation focus on three areas: Technological advances community. This will draw on the strengths of feedback from campus organisations. to (i) improve mental health and/or associated the West Cambridge Campus and the wider life care pathways and (ii) to support healthy ageing Health Informatics sciences ecosystem. In collaboration with ABHI, and community services; and (iii) value-based work will encourage regional inward investment Chaired by Professor Patrick Maxwell, Regius contracting and reimbursement reform to drive from the healthtech industry, while continuing Professor of Physic, School of Clinical better patient outcomes. to offer partnership opportunities for pharma Medicine, University of Cambridge and biotech companies. In collaboration with Eastern AHSN, an initial Education focus will be to build on the success of the Rare Diseases Sprint Exemplar Innovation Project Chaired by Professor John Wallwork, Chair, to form an application for a Digital Innovation Royal Papworth Hospital NHS Foundation Trust Hub. Co-ordinated by HDR UK and funded by The group will assess CUHP’s current education the UKRI Industry Strategy Challenge Fund, strategy, considering current workforce the Digital Innovation Hubs will move towards the creation of a UK-wide infrastructure for

Annual Impact Review 2018-19 16 CPFT strives to improve the health and wellbeing of the people we care for, supporting innovation that delivers enhanced patient care across our mental health and community services. As such, we look forward to working with CUHP and partners to identify and implement new technological advances and competitive industry solutions which improve our clinical service and patient outcomes – aims wholly aligned with our Three-Year Trust Strategy.”

Tracy Dowling Chief Executive, Cambridgeshire and Peterborough NHS Foundation Trust (CPFT)

17 Our year in colour

Annual Impact Review 2018-19 18 We would like to thank our partners and all those involved in the development of this Impact Review, including those who have given permission to use images. The Abcam photograph used on p18 is copyrighted to Abcam. Cambridge University Health Partners (CUHP) Box 146 – Addenbrooke’s Hospital, Cambridge Biomedical Campus, Cambridge, CB2 0QQ Telephone: CUHP office +44 1223 254981 Email: [email protected] @CUHPartners www.cuhp.org.uk