Canine Flea & Tick Control Comparison

Product Active Ingredients Age Kills Fleas Adult Kills Flea Eggs Kills Flea Larva Kills Ticks (Multiple Species) Lice Sarcoptic mange Biting Flies Mosquitoes Heartworm Ear Mites Dosage

Topical Application

22.1% Amitraz CERTIFECT™ 9.8% Fipronil 8 weeks X X X X X X Once per month 8.8% (S)-Methoprene

6.01% Fipronil ® 8 weeks Once per month effitix 44.88% Permethrin X X X X X X X X

9.8% Fipronil ® 8 weeks Once per month FRONTLINE Plus for Dogs 8.8% (S)-Methoprene X X X X X X

50.0% Etofenprox 9.10% Piperonyl Butoxide Flea & Tick Spot On for Dogs 0.91% N-Octyl Bicycloheptene Dicarbozimide (MGK 264®) 6 months X X X X Once per month (Bio Spot Active Care™) 0.45% Pyriproxyfen (Nylar®) 0.23% (S)-Methoprene

® 30.0% Etofenprox Flea & Tick SpotOn for Dogs 3.6% (S)-Methoprene 12 weeks X X X X Once per month (Adams™) 5.0% Piperonyl Butoxide

8.8% Imidacloprid K9 advantix® II 44.0% Permethrin 7 weeks X X X X X X X Once per month 0.44% Pyriproxyfen

50.0% Permethrin ® 12 weeks Once per month LIBERTY 50 Plus IGR 1.20% Pyriproxyfen X X X X X X

9.8% Fipronil 12 weeks Once per month PARASTAR™ plus 5.2% Cyphenothrin X X X X revolution™ Selemectin 6 weeks X X X* X X X X Once per month

9.8% Fipronil 8 weeks Once per month Spectra Sure™ IGR for Dogs 8.8% (S)-Methoprene X X X X X X

9.8% Fipronil 12 weeks Once per month Spectra Sure™ Plus for Dogs 8.8% Cyphenothrin X X X X X X

40% Cyphenothrin 12 weeks Once per month TriForce™ Canine 2.0% Pyriproxyfen X X X X X

Collar

4.5% Flumethrin ® 12 weeks Every 8 months seresto for Dogs 10% Cyphenothrin X X X X X X

PREVENTIC® Dog Tick Collar 9% Amitraz 12 weeks X Every 3 months

Shampoo, Sprays and Dips

0.50% Etofenprox ADAMS™ plus Flea & Tick 0.27% (S)-Methoprene 10 weeks X X X X Once per month 1.75% Piperonyl Butoxide Canine Flea & Tick Control Comparison

Product Active Ingredients Age Kills Fleas Adult Kills Flea Eggs Kills Flea Larva Kills Ticks (Multiple Species) Lice Sarcoptic mange Biting Flies Mosquitoes Heartworm Ear Mites Dosage

0.10% (S)-Methoprene 7-10 days 0.15% Pyrethrins 12 weeks ADAMS™ plus Flea/Tick Shampoo X X X X as needed 1.88% Piperonyl Butoxide

0.97% Pyrethrins 7 days 12 weeks ADAMS™ Pyrethrin Dip 3.74% Piperonyl Butoxide X X X X X as needed

0.15% Pyrethrins 7 days ® 12 weeks Ecto-Soothe 3X 1.50% Piperonyl Butoxide X X as needed

0.112% Pyrethrins 0.100% Piperonyl Butoxide Repeat every 6 months Flea & Tick Spray for Dogs 0.479% N-Octyl Bicycloheptene Dicarboximide (MGK 264®) X X X 2 weeks 0.125% 2-[1-Methyl-2-(4-phenoxyphenoxy) ethoxy] pyridine

0.15% Pyrethrins 1.50% Piperonyl Butoxide Repeat every ® 12 weeks Flys-Off Mist 0.50% N-Octyl Bicycloheptene Dicarboximide (MGK 264®) X X X 9 days 0.50% Di-n-Propyl Isocinchomeronate

FRONTLINE® Spray 0.29% Fipronil 8 weeks X X X X Once a month

0.12% d-trans Allethrin 14 days ® 12 weeks Mycodex Flea & Tick Shampoo 0.50% Piperonyl Butoxide X as needed

0.15% Pyrethrin 7 days 0.30% Piperonyl Butoxide 12 weeks VF Flea & Tick Shampoo X X as needed 0.479% N-Octyl Bicycloheptene Dicarboximide (MGK 264®)

Oral Medication

4 weeks and One time; ® Nitenpyram Capstar over 2 lbs X repeat as needed

8 weeks and ® Afoxolaner Once a month NexGard over 4 lbs X X

Sentinel® Spectrum® Milbemycin Oxime (treats/controls tapeworms, whipworms, roundworms, Lufenuron 6 weeks X X Once a month hookworms) Praziquantel

*Only controls one species of tick.