Department of Critical Care Medicine ANNUAL REPORT FY2018 CLINICAL CARE EDUCATION RESEARCH 614 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261 www.ccm.pitt.edu Annual Report FY18 | 1 Table of Contents Table of Charts & Graphs ............................................................................................ 2 Critical Care Medicine General Description ........................................................... 3 Mission Statement ................................................................................................. 4 Major Academic Achievements ............................................................................. 4 High-Impact Publications ....................................................................................... 7 Summary of Clinical Activities ............................................................................... 8 Summary of Research Activities ............................................................................ 9 Summary of Teaching Activities .......................................................................... 12 Summary of Faculty Data .................................................................................... 15 Clinical Activities .......................................................................................................... 16 Adult Critical Care Division .................................................................................. 16 Pediatric Critical Care Division ............................................................................. 21 Research Activities ...................................................................................................... 23 Research Centers ................................................................................................ 25 Professional Conferences .................................................................................... 34 Training Grants .................................................................................................... 36 Individual Faculty Research Summaries .............................................................. 41 Teaching Activities ...................................................................................................... 78 Medical Students, Residents, APPs, & Observerships ......................................... 78 Adult Division Fellowship Program ...................................................................... 80 Pediatric Division Fellowship Program ................................................................ 94 Faculty Data ................................................................................................................ 102 Promotions, New Hires & Summary of Employees ........................................... 102 Three-Year Bibliography .......................................................................................... 104 Adult Division ..................................................................................................... 104 Pediatric Division ............................................................................................... 133 Annual Report FY18 | 2 Table of Charts & Graphs Core Lectures Subject Areas ..................................................................................... 82 Professionalism and Leadership Course Curriculum ......................................... 83 Grand Rounds / Research Conferences ................................................................. 91 Evidence-Based Journal Club Series ....................................................................... 93 Pediatric Fellowship Educational Conferences ................................................... 99 Faculty Promotions ................................................................................................... 102 Faculty New Hires ...................................................................................................... 102 Summary of Employees ........................................................................................... 103 Annual Report FY18 | 3 Critical Care Medicine General Description Introduction The Department of Critical Care Medicine at the University of Pittsburgh was founded on December 5, 2001. Our department holds the distinction of being the first stand-alone department of critical care medicine in the United. States. Since 2008 the Department has been led by Derek Angus, MD, MPH, who holds the Mitchell P. Fink Chair of Critical Care Medicine, an endowed chair that was established to honor the founding chairman of the Department. Under Dr. Angus’ leadership fiscal year 2017/2018 was a year of dynamic growth and positive change. The Department includes 63 full-time faculty members and three part-time faculty within two divisions: Adult and Pediatric. The Department also has 19 secondary faculty members. During FY18, 17 new faculty members were recruited to support the Department’s three core missions: clinical care, education, and research. Cutting edge clinical care: The Department provides effective and efficient care to critically ill patients in UPMC Presbyterian Hospital, UPMC Mercy Hospital, UPMC Magee-Womens Hospital, UPMC Children’s Hospital of Pittsburgh, and the Veterans Affairs Pittsburgh Medical Center. In total, our faculty and fellows provided critical care services in 15 ICUs across six hospitals in Pittsburgh. We manage and provide intensivist coverage for two ICUs at St. Joseph’s Children’s Hospital (SJCH) in Tampa, Florida and provide SJCH with telemedicine support from CHP, one ICU at Florida Children’s Hospital, Orlando, and an ICU at Altoona, Pennsylvania as well as provide telemedicine support for child transplant patients at University of Virginia, Charlottesville. In addition to working within the ICU, we lead the hospital-wide rapid response teams at covered hospitals, providing an essential safety net to hospitalized patients outside the ICU. Our faculty lead renowned programs in solid organ transplant, extracorporeal membrane support, and obstetric critical care, helping to position UPMC as a national leader in the care of the critically ill patient. Our faculty also actively contribute to various management committees for the UPMC Health System, ensuring seamless integration between UMPC ICUs and other important service lines. Interdisciplinary education: We proudly run the oldest and largest critical care medicine training program in the country, emphasizing clinical training that is both multidisciplinary and completely integrated into the work flow of acute care medicine. Graduates from our six clinical fellowships leave with a level of expertise and competence based on real-world challenges and close mentorship that allows them to confidently take on leadership roles in critical care medicine around the world. Many of the present and past chairs of academic critical care medicine and anesthesiology departments (in many countries anesthesiology departments traditionally run critical care medicine programs) were or are our graduates. These highly visible and influential critical care medicine leaders amplify the impact our training program has outside our borders. Furthermore, we have two T32 research development training programs: one in pediatrics and the other in adult medicine. No other critical care medicine program can make this claim. World leading research: Our faculty perform innovative, ground-breaking research in basic, translational, and clinical science, advancing the science of critical care medicine and leading to improved patient outcomes world-wide. Our research activities far exceed national benchmarks, with annual federal funding amount of more than $12 million. We currently hold 29 R01 investigator-initiated awards; four R21 Pilot Awards; three U- level Cooperative Agreements, one K24 Mid-Career Investigator Award; one R18 Research Demonstration and Dissemination Project; one DP2 NIH Director’s New Innovator Award; four K Career Development Awards; one F30 Individual Fellowship; two T32 Training Grants; and 23 non-federal awards. This year alone we have Annual Report FY18 | 4 received 27 new grants totaling $5.3 million. Our grant activity is part and parcel with exceptional research productivity--our faculty and trainees combined to publish more than 390 peer-reviewed original research papers over the past 12 months. Furthermore, our faculty are widely sought as speakers at leading symposia and professional conferences. Twenty-nine of our faculty members have given 202 major invited lectures at major conferences in the field as well as in many other national and international forums. Finally, our faculty hold three editorships; six associate editorships; seven section, subject, and series editorships; and 22 memberships on the editorial boards of major acute care journals, including JAMA, the American Journal of Respiratory & Critical Care Medicine, Critical Care Medicine, and Pediatric Critical Care Medicine, among others. These impressive statistics speak to the depth of our academic commitment and investigative scope of our faculty members. Mission Statement The Mission of the Department of Critical Care Medicine (CCM) is to provide exemplary care for critically ill patients, conduct cutting edge research related to life-threatening acute medical problems, and to educate tomorrow’s leaders in the field of critical care medicine. We believe that with the strong support of the University, the School of Medicine, and the UPMC Health System,