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Selection of Substances for the 3Rd Watch List Under the Water Framework Directive Selection of substances for the 3rd Watch List under the Water Framework Directive Livia Gomez Cortes, Dimitar Marinov, Isabella Sanseverino, Anna Navarro Cuenca, Magdalena Niegowska, Elena Porcel Rodriguez, and Teresa Lettieri 2020 EUR 30297 EN This publication is a Technical report by the Joint Research Centre (JRC), the European Commission’s science and knowledge service. It aims to provide evidence-based scientific support to the European policymaking process. The scientific output expressed does not imply a policy position of the European Commission. Neither the European Commission nor any person acting on behalf of the Commission is responsible for the use that might be made of this publication. For information on the methodology and quality underlying the data used in this publication for which the source is neither Eurostat nor other Commission services, users should contact the referenced source. The designations employed and the presentation of material on the maps do not imply the expression of any opinion whatsoever on the part of the European Union concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Contact information Name: Teresa Lettieri Address: Via E. Fermi, 2749, 21027 Ispra (VA), Italy Email: [email protected] Tel.: 00390332789868 EU Science Hub https://ec.europa.eu/jrc JRC121346 EUR 30297 EN PDF ISBN 978-92-76-19426-2 ISSN 1831-9424 doi:10.2760/194067 Print ISBN 978-92-76-19425-5 ISSN 1018-5593 doi:10.2760/240926 Luxembourg: Publications Office of the European Union, 2020 The reuse policy of the European Commission is implemented by the Commission Decision 2011/833/EU of 12 December 2011 on the reuse of Commission documents (OJ L 330, 14.12.2011, p. 39). Except otherwise noted, the reuse of this document is authorised under the Creative Commons Attribution 4.0 International (CC BY 4.0) licence (https://creativecommons.org/licenses/by/4.0/). This means that reuse is allowed provided appropriate credit is given and any changes are indicated. For any use or reproduction of photos or other material that is not owned by the EU, permission must be sought directly from the copyright holders. All content © European Union, 2020 How to cite this report: Livia Gomez Cortes, Dimitar Marinov, Isabella Sanseverino, Anna Navarro Cuenca, Magdalena Niegowska, Elena Porcel Rodriguez and Teresa Lettieri, Selection of substances for the 3rd Watch List under the Water Framework Directive, EUR 30297 EN, Luxembourg: Publications Office of the European Union, 2020, ISBN 978-92-76-19426-2, doi:10.2760/194067, JRC121346. Contents Executive summary ..................................................................................................... 4 1 Introduction ......................................................................................................... 7 2 Process for selecting candidate substances for the Watch List (WL) ........................................... 8 2.1 Sources of information and databases for hazard properties and analytical methods ................. 8 2.1.1 Hazard information ................................................................................... 8 2.1.2 Analytical methods ................................................................................. 11 3 Candidate substances identified which should be monitored in sediment or biota ......................... 12 3.1 Criteria for selecting substances for sediment and biota monitoring .................................. 12 3.2 List of substances to be monitored in sediment or biota ................................................ 12 3.3 Rationale for the selection ................................................................................. 16 2-Ethylhexyl 4-methoxycinnamate (EHMC, sunscreen agent) ............................................. 16 Group of pyrethroids (bifenthrin, permethrin, deltamethrin and esfenvalerate) ......................... 16 4 Selection of new substances for the Watch List (WL) ......................................................... 18 4.1 Criteria for identification of candidate substances for WL update ..................................... 18 4.2 List of substances fulfilling the criteria ................................................................... 19 4.3 Rationale for the selection ................................................................................. 33 Industrial products ............................................................................................ 33 Pharmaceuticals .............................................................................................. 36 Plant protection products and biocides ..................................................................... 42 4.4 Other substances proposed as candidates for the next Watch List (WL) ............................... 45 5 Conclusions........................................................................................................ 53 References ............................................................................................................ 56 List of abbreviations and definitions ................................................................................ 61 List of figures ......................................................................................................... 63 List of tables .......................................................................................................... 64 Supplementary information .......................................................................................... 65 Annex I: Outcome of the workshop “Analytical methods for substances in the Watch List under the Water Framework Directive” held at the JRC (Ispra, Italy) in October 2018 ............................................. 66 Annex II: Hazard properties, available monitoring data, RQ, and STE scores ..................................... 68 Annex III: Factsheets.................................................................................................. 85 Bifenthrin (CAS N. 82657-04-3) ................................................................................. 86 Chromium (CAS N. 7440-47-3): chromium trioxide, other Cr (VI) compounds (CAS N. 1333-82-0; 18540- 29-9) and Cr (III) (CAS N. 16065-83-1, 1308-38-9) ........................................................... 94 Clotrimazole (CAS N. 23593-75-1) ............................................................................ 103 Cyanide-Free (CAS N. 57-12-5)/ Hydrogen Cyanide (CAS N. 74-90-8) ..................................... 107 Deltamethrin (CAS N. 52918-63-5) ........................................................................... 117 Dimoxystrobin (CAS N. 149961-52-4) ........................................................................ 125 i 2-Ethylhexyl-4-methoxycinnamate, EHMC (CAS N. 5466-77-3)/2-Ethylhexyl trans 4-methoxycinnamate (CAS N. 83834-59-7) ........................................................................................... 131 Epoxiconazole (CAS N. 133855-98-8, 135319-73-2, formerly 106325-08-0) ........................... 137 Esfenvalerate (CAS N. 66230-04-4) .......................................................................... 142 Famoxadone (CAS N.131807-57-3) .......................................................................... 149 Fluconazole (CAS N. 86386-73-4) ............................................................................ 154 Imazalil (enilconazole) (CAS N. 35554-44-0)................................................................. 158 Ipconazole (CAS N. 125225-28-7) ............................................................................ 163 Metconazole (CAS N. 125116-23-6) .......................................................................... 168 Miconazole (CAS N. 22916-47-8) ............................................................................. 173 Norethisterone (CAS N. 68-22-4) .............................................................................. 178 Omeprazole (CAS N. 73590-58-6) and its metabolite 4-hydroxy omeprazole sulphide (CAS N. 103876-98- 8) ............................................................................................................. 183 Penconazole (CAS N. 66246-88-6) ............................................................................ 188 Permethrin (CAS N. 52645-53-1) ............................................................................. 192 Prochloraz (CAS N. 67747-09-5) .............................................................................. 200 Propiconazole (CAS N. 60207-90-1) .......................................................................... 205 Sulfamethoxazole (CAS N. 723-46-6) ........................................................................ 210 Tebuconazole (CAS N. 107534-96-3) ......................................................................... 216 Tetraconazole (CAS N. 112281-77-3) ........................................................................ 221 Trimethoprim (CAS N. 738-70-5) .............................................................................. 226 Venlafaxine (CAS N. 93413-69-5) ............................................................................ 233 ii Acknowledgements We thank Helen Clayton (DG ENV) for her comments and suggestions. We are grateful to William H. Gaze (ECEHH) and to Caroline Whalley and other European Environment Agency (EEA) colleagues for providing helpful information
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