DNAJA3 Antibody Cat. No.: 22-642

DNAJA3 Antibody

Immunohistochemistry of paraffin-embedded rat brain Immunohistochemistry of paraffin-embedded rat kidney using DNAJA3 Antibody (22-642) at dilution of 1:100 (40x using DNAJA3 Antibody (22-642) at dilution of 1:100 (40x lens). lens).

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 221-480 IMMUNOGEN: of human DNAJA3 (NP_005138.3).

TESTED APPLICATIONS: IHC, WB

WB: ,1:500 - 1:2000 APPLICATIONS: IHC: ,1:50 - 1:200

POSITIVE CONTROL: 1) BT-474

2) Jurkat

October 1, 2021 1 https://www.prosci-inc.com/dnaja3-antibody-22-642.html 3) 293T

4) HepG2

5) Mouse liver

6) Mouse kidney

PREDICTED MOLECULAR Observed: 52kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: DNAJA3

ALTERNATE NAMES: DNAJA3, DnaJ protein Tid-1, HTID-1, HCA57, TID1

GENE ID: 9093

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival BACKGROUND: and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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October 1, 2021 2 https://www.prosci-inc.com/dnaja3-antibody-22-642.html