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KENTUCKY’S BEST EDUCATED WORKFORCE Albert B. Chandler Medical Center University of Kentucky Published by $12 . RESEARCH, INNOVATION & COMMERCIALIZATION From Bench to Bedside UK receives $20 million to accelerate research from lab to healthcare solutions N June 2011, the University of Kentucky was awarded a $20 million grant by the National IInstitutes of Health (NIH) to help move research discoveries to healthcare solutions more quickly through translational science, a discipline charged with helping research make the translation “from the bench to the bedside.” The five-year funding, awarded through the NIH’s institutional Clinical and Translational Science Awards (CTSA) program, will be used to support research at UK’s Center for Clinical and Translational Science, making it part of a select national biomedical research consortium. The UK center is led by Dr. Philip Kern, associate provost for clinical and translational science, who will serve as principal investigator of Dr. Philip Kern, the program. Kern Director, UK emphasized the Center for Clinical multidisciplinary, andTranslational collaborative nature of Science translational research. “One example at UK is the integration of our research strengths in cancer, heart disease and diabetes with our strengths in pharmaceutical sciences and biomedical engineering to and the recognition that The $20 million grant by the National Institutes of develop novel drugs and medical UK is among Health will help move research discoveries to devices,” the nation’s top healthcare solutions more quickly through Kern said. biomedical research translational science and recognizes UK among the top biomedical research universities. The funding will be used to support universities. essential infrastructure, including “This award is the supporting the Clinical Research end result of much hard Development and Operations Center work and diligence by Kentucky and beyond, said Dr. Michael (CR-DOC) located at the UK Albert Kumble many,many people at Karpf, UK’s executive , where Subbaswamy, the university who have vice president for B. Chandler Hospital UK Provost patients participate in clinical research demonstrated their health affairs. studies. It also will be used for expertise in clinical “Having a top biomedical research educational programs for future research and their ability program is imperative in our plan to investigators, to build successful become a major regional academic for community engagement, to interdisciplinary medical center, and being selected for the fund research pilot grants and an collaborations,” CTSA award is an acknowledgement we informatics program. Subbaswamy said. are continuing to do what we need to do UK established its own clinical and The new CTSA will to meet that goal,” Karpf said. UK’s translational research center is translational science center in 2006 with the Dr. Michael Karpf, enable the university to goal of becoming a consortium member. UK ExecutiveVice accomplish goals that a collaboration of more than 200 UK Provost Kumble Subbaswamy said President for affect the health individuals from 12 UK colleges, the the award provides significant funding Health Affairs outcomes of people in Offices of the President, Provost, 20 The Lane Report’s 2011-2012 Market Review of the Bluegrass Commonwealth Collaboratives Address Kentucky’s Greatest Needs Projects improve health, education, economy,environment, natural resources and quality of life K’s Commonwealth Collaboratives, which began in 2006 to address the state’s most Uurgent needs, benefit Kentuckians in a variety of ways. The collaboratives, now numbering 47 projects, are designed to improve the health, education, economy, environment, natural resources and quality of life for Kentuckians. Two collaboratives were recently named Exemplary Projects by the Association of Public and Land Grant Universities (APLU): the Clean Indoor Air Initiative led by Ellen Hahn of the UK College of Nursing and the Reclamation of Surface-Mined Lands Initiative led by Chris Energy Efficient Housing project. Chris Barton of the UK Department of Forestry Barton of UK’s Department of Forestry Its goal is to design highly energy- leads the Reclamation of Surface-Mined Lands in the College of Agriculture. efficient housing units for less than Initiative, one of 47 projects known as Hahn began her project to prevent $100,000 to be manufactured in Commonwealth Collaboratives. lung cancer by reducing exposure to Somerset, Ky., located in a region whose secondhand smoke and radon. The houseboat manufacturing industry has uky.edu/UE/CC/index.php initiative seeks to reduce Kentuckians’ been decimated by the recession. The Following are other examples of exposure to indoor air pollutants project aims to replace energy-inefficient research being done at UK in various through research, education, air quality mobile homes with efficient models. colleges and healthcare-related areas. monitoring and policy development. The UK Colleges of Dentistry and The project has resulted in an increase Medicine are achieving great success on a UK COLLEGE OF AGRICULTURE in Kentuckians covered by smoke-free laws Commonwealth Collaboratives project Jim Newberry, Executive-in-Residence, from zero to 34 percent. In Lexington, it aimed at reducing the number of low Development and Commercialization has produced a 32 percent reduction in birth-weight babies in Kentucky by of New Technologies adult smoking and a 22 percent decline in improving the oral health of pregnant S-129 Agricultural Science Building North emergency room visits for asthma. women. Poor oral health is linked to an Lexington, KY 40546-0091 Barton leads a land reclamation increased incidence of low birth-weight ca.uky.edu initiative including faculty in UK’s infants as well as diabetes and heart departments of Biosystems and Agricultural disease. About 5,000 premature, low From 2007-2009, Engineering, and Mining Engineering. The birth-weight babies are born each year in researchers in the project is designed to develop new Kentucky, an increase of nearly 20 UK College of standards for industry reclamation of strip percent over the last 10 years. Agriculture mined lands through model projects in The College of Dentistry is working accounted for more than reforestation, headwater stream restoration, with community partners to increase the $100 million in research water quality improvement, wildlife habitat availability of dental care in rural clinics. spending, or 15.4 enhancement and atmospheric carbon The Jim Newberry, percent of the research Centering Pregnancy Smiles Executive- dioxide mitigation. The initiative seeks to project focuses on reducing the number of in-Residence spending at UK during promote carbon sequestration through low birth-weight babies, improving overall that time. Inventors in reforestation, and its methods are designed health and reducing the high healthcare the college were responsible for 45.6 percent to reduce flooding and decrease water costs associated with premature and low of UK’s revenue from intellectual property pollution. It is targeted specifically on birth-weight infants. The initiative is license fees for 2007-2009, and in these Eastern Kentucky and Appalachia. showing impressive results. At the Women’s economic times, that license fee revenue is “The loss of Appalachian forests due to Health Center in Madisonville, Ky., the vitally important. coal mining is a complex issue because the project has resulted in a reduction in Start-up companies continue to spring region struggles to balance the need for jobs preterm birth rates from 18 percent to 6 from the research conducted by college and cheap energy with the desire to maintain percent and a reduction in low birth-weight faculty, post-docs and graduate students. its unique forested ecosystem,” Barton said. deliveries from 11 percent to 3 percent. These researchers and teachers also advise Another successful Commonwealth UK Commonwealth other ag-related companies outside the Collaborative is the Houseboats to Collaboratives university environs. Within the Kentucky The Bluegrass: Best-Educated Workforce in Kentucky 21 RESEARCH, INNOVATION & COMMERCIALIZATION Tobacco Research and Development Center is the Agricultural Technologies Commercialization Center, an incubator providing laboratory and office space for start-ups based on plant science and agricultural technologies. UK COLLEGE OF ARTS & SCIENCES Mark Kornbluh, Dean 202 Patterson Office Tower Lexington, KY 40506-0027 (859) 257-8354 as.uky.edu Many UK research professors are housed in the UK College of Arts & Sciences, and the majority of their research is supported by Mark Kornbluh, grants and contracts Dean, UK College from federal, state and of Arts & Sciences private funding agencies, UK chemistry professor John Anthony’s research focuses on the development of solar cells created with and from foundations, including the organic or carbon-based materials. National Science Foundation, the National Institutes of Health, the Guggenheim and the National Endowment for the Chemistry Professor Pushes Solar Boundaries Humanities. HE sun’s rays stream into countless homes and businesses across the globe. While traditional solar College faculty helped attract nearly panels have been at work harvesting this abundant natural energy resource for several decades, UK $50 million in grants in fiscal year 2010 chemistry professor John Anthony is pushing the boundaries of new solar cell development. and are responsible for nearly $18 TAnthony’s research focuses