Research Article Typologies of Extreme Longevity Myths
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Longevity Extension from a Socioeconomic Perspective: Plausibility, Misconceptions, and Potential Outcomes
Sound Decisions: An Undergraduate Bioethics Journal Volume 2 Issue 1 Article 4 2016-12-15 Longevity Extension from a Socioeconomic Perspective: Plausibility, Misconceptions, and Potential Outcomes Eric Ralph University of Puget Sound Follow this and additional works at: https://soundideas.pugetsound.edu/sounddecisions Part of the Bioethics and Medical Ethics Commons Recommended Citation Ralph, Eric (2016) "Longevity Extension from a Socioeconomic Perspective: Plausibility, Misconceptions, and Potential Outcomes," Sound Decisions: An Undergraduate Bioethics Journal: Vol. 2 : Iss. 1 , Article 4. Available at: https://soundideas.pugetsound.edu/sounddecisions/vol2/iss1/4 This Article is brought to you for free and open access by the Student Publications at Sound Ideas. It has been accepted for inclusion in Sound Decisions: An Undergraduate Bioethics Journal by an authorized editor of Sound Ideas. For more information, please contact [email protected]. Ralph: Longevity Extension Longevity Extension from a Socioeconomic Perspective: Plausibility, Misconceptions, and Potential Outcomes Eric Ralph Introduction In the last several decades, a significant amount of progress has been made in pursuits to better understand the process of aging and subsequently gain some level of control over it. Current theories of aging are admittedly lacking, but this has not prevented biogerontologists from drastically increasing the longevity of yeast, drosophilae, worms, and mice (Vaiserman, Moskalev, & Pasyukova 2015; Tosato, Zamboni et al. 2007; Riera & Dillin 2015). Wide-ranging successes with gene therapy and increased comprehension of the genetic components of aging have also recently culminated in numerous successes in extending the longevity of animals and the first human trial of a gene therapy to extend life through telomerase manipulation is already underway, albeit on a small scale (Mendell et al. -
Khwājā Khadir and the Fountain of Life, in the Tradition of Persian and Mughal Art
Khwājā Khadir and the Fountain of Life, in the Tradition of Persian and Mughal Art By A. K. Coomaraswamy Studies in Comparative Religion, Vol. 4, No. 4. (Autumn, 1970) © World Wisdom, Inc. www.studiesincomparativereligion.com IN India, the Prophet, Saint, or Deity known as Khwājā Khizr (Khadir), Pīr Badar, or Rājā Kidār, is the object of a still surviving popular cult, common to Muslims and Hindus. His principal shrine is on the Indus near Bakhar, where he is worshipped by devotees of both persuasions; the cult is however hardly less widely diffused in Bihar and Bengal. In the Hindu cult, the Khwājā is worshipped with lights and by feeding Brahmans at a well, and alike in Hindu and Muslim practice, by setting afloat in a pond or river a little boat which bears a lighted lamp. Iconographically Khwājā Khizr is represented as an aged man, having the aspect of a fakir, clothed entirely in green,1 and moving in the waters with a "fish" as his vehicle. The nature of Khwājā Khizr can be inferred from his iconography as outlined above, and also from the Indian legends. In the ballad of Niwal Daī, which is localized at Safīdam2 in the Pañjāb, Niwal Daī is the daughter of Vāsuki, the chief of the Serpents. The Aryan Pāndava Rājā Pariksit has encountered Vāsuki, and forced him to promise his daughter to him in marriage, though from Vāsuki's point of view this is a disgraceful misalliance. Vāsuki is then stricken with leprosy, owing to a curse pronounced by the Priest Sījī3 whose cows have been bitten by the Serpents. -
World Population Ageing 2019
World Population Ageing 2019 Highlights ST/ESA/SER.A/430 Department of Economic and Social Affairs Population Division World Population Ageing 2019 Highlights United Nations New York, 2019 The Department of Economic and Social Affairs of the United Nations Secretariat is a vital interface between global policies in the economic, social and environmental spheres and national action. The Department works in three main interlinked areas: (i) it compiles, generates and analyses a wide range of economic, social and environmental data and information on which States Members of the United Nations draw to review common problems and take stock of policy options; (ii) it facilitates the negotiations of Member States in many intergovernmental bodies on joint courses of action to address ongoing or emerging global challenges; and (iii) it advises interested Governments on the ways and means of translating policy frameworks developed in United Nations conferences and summits into programmes at the country level and, through technical assistance, helps build national capacities. The Population Division of the Department of Economic and Social Affairs provides the international community with timely and accessible population data and analysis of population trends and development outcomes for all countries and areas of the world. To this end, the Division undertakes regular studies of population size and characteristics and of all three components of population change (fertility, mortality and migration). Founded in 1946, the Population Division provides substantive support on population and development issues to the United Nations General Assembly, the Economic and Social Council and the Commission on Population and Development. It also leads or participates in various interagency coordination mechanisms of the United Nations system. -
JUAN PONCE DE LEON Reading Comprehension
JUAN PONCE DE LEON Reading Comprehension Juan Ponce de Leon was born in 1460 in Santeveras, Spain. De Leon was an explorer and fighter from an early age. He helped fight the Muslims in southern Spain in the early 1490s. He was on board Christopher Columbus's second expedition to the Americas in 1493. Rather than returning to Spain, the adventurer remained at an island called Santo Domingo (now called the Dominican Republic). De Leon was soon appointed as the governor of the Higuey region of Santo Domingo. Like many Spanish explorers, he was bloodthirsty for gold. When he heard rumors that a nearby island called Borinquen (now Puerto Rico) was full of gold, he invaded the island and brutally conquered the natives. He was soon appointed governor of the island but lost his title in 1511 because of his extreme brutality towards the natives. De Leon's misfortunes as governor did not stop him from looking for gold and the Fountain of Youth. During his search, he conquered many islands, including Bimini. After returning to Puerto Rico, de Leon took three ships and 200 men on a mission to explore lands to the north. De Leon hoped to find the Fountain of Youth, a mythical spring that was said to make anyone who drank its water young forever. After making several stops at Caribbean islands, de Leon and his men reached the east coast of Florida (St. Augustine) on April 2, 1513. He named the land "Pascua de Florida," or Feast of Flowers because he discovered it on Palm Sunday. -
The Age of Exploration (Also Called the Age of Discovery) Began in the 1400S and Continued Through the 1600S. It Was a Period Of
Activity 1 of 3 for NTI May 18 - 22 - Introduction to Exploration of North America Go to: https://www.ducksters.com/history/renaissance/age_of_exploration_and_discovery.php Click on the link above to read the article. There is a feature at the bottom that will allow you to have the text read to you, if you want. After you read the article, answer the questions below. You can highlight or bold your answers if completing electronically. I have copied the website text below if you need it. The Age of Exploration (also called the Age of Discovery) began in the 1400s and continued through the 1600s. It was a period of time when the European nations began exploring the world. They discovered new routes to India, much of the Far East, and the Americas. The Age of Exploration took place at the same time as the Renaissance. Why explore? Outfitting an expedition could be expensive and risky. Many ships never returned. So why did the Europeans want to explore? The simple answer is money. Although, some individual explorers wanted to gain fame or experience adventure, the main purpose of an expedition was to make money. How did expeditions make money? Expeditions made money primarily by discovering new trade routes for their nations. When the Ottoman Empire captured Constantinople in 1453, many existing trade routes to India and China were shut down. These trade routes were very valuable as they brought in expensive products such as spices and silk. New expeditions tried to discover oceangoing routes to India and the Far East. Some expeditions became rich by discovering gold and silver, such as the expeditions of the Spanish to the Americas. -
Dissecting Aging and Senescence—Current Concepts and Open Lessons
cells Review Dissecting Aging and Senescence—Current Concepts and Open Lessons 1,2, , 1,2, 1 1,2 Christian Schmeer * y , Alexandra Kretz y, Diane Wengerodt , Milan Stojiljkovic and Otto W. Witte 1,2 1 Hans-Berger Department of Neurology, Jena University Hospital, 07747 Jena, Thuringia, Germany; [email protected] (A.K.); [email protected] (D.W.); [email protected] (M.S.); [email protected] (O.W.W.) 2 Jena Center for Healthy Ageing, Jena University Hospital, 07747 Jena, Thuringia, Germany * Correspondence: [email protected] These authors have contributed equally. y Received: 2 October 2019; Accepted: 13 November 2019; Published: 15 November 2019 Abstract: In contrast to the programmed nature of development, it is still a matter of debate whether aging is an adaptive and regulated process, or merely a consequence arising from a stochastic accumulation of harmful events that culminate in a global state of reduced fitness, risk for disease acquisition, and death. Similarly unanswered are the questions of whether aging is reversible and can be turned into rejuvenation as well as how aging is distinguishable from and influenced by cellular senescence. With the discovery of beneficial aspects of cellular senescence and evidence of senescence being not limited to replicative cellular states, a redefinition of our comprehension of aging and senescence appears scientifically overdue. Here, we provide a factor-based comparison of current knowledge on aging and senescence, which we converge on four suggested concepts, thereby implementing the newly emerging cellular and molecular aspects of geroconversion and amitosenescence, and the signatures of a genetic state termed genosenium. -
Final April Longevity
HEALTH AND STRESS The Newsletter of The American Institute of Stress Number 4 April 2010 STRESS, HEALTHY AGING & CLUES FOR LIVING TO 100 KEYWORDS: Methuselah gene, Alexander the Great, "The Wandering Jew", Paracelsus, Ponce De Leon, David Copperfield, James Hilton, "zest for life", stable lifestyles, Milano and INDY genes, "founder effect", pogroms and the Holocaust, CETP, humanin, IGF-1, sirtuin, genetic testing scams Why do some people live so much longer and healthier lives than others? Heredity is obviously an important influence, since extreme longevity seems to run in families. The Bible tells us that Methuselah, who had very long- lived ancestors dating back to Noah, allegedly died at the age of 969 and begat Lamech when he was 187 years old. Support comes from unique Iceland birth and death records going back to the Vikings, showing that individuals who lived to be over 90 were much more likely to be closely related than controls with average life spans. Researchers later identified a "Methuselah" longevity gene that also seemed to confer prolonged fertility. Also Included In This Issue The Boston New England Centenarian Study had previously reported that all the Healing Waters, The Fountain Of Youth centenarians studied had similar genes And Elixirs Of Life And Longevity that protected them from age-related conditions, including heart disease, cancer Sir Robert McCarrison's Hunzas And The Search For Shangri-La and dementia. Siblings were four times more likely than average to reach 90 and Alexander Leaf's Travels To Confirm And their children lived 10 -15 years longer Explain Centenarian Claims than the norm. -
Living to 100”
The Likelihood and Consequences of “Living to 100” Leonard Hayflick, Ph.D. Professor of Anatomy, Department of Anatomy University of California, San Francisco, School of Medicine Phone: (707) 785-3181 Fax: (707) 785-3809 Email: [email protected] Presented at the Living to 100 Symposium Orlando, Fla. January 5-7, 2011 Copyright 2011 by the Society of Actuaries. All rights reserved by the Society of Actuaries. Permission is granted to make brief excerpts for a published review. Permission is also granted to make limited numbers of copies of items in this monograph for personal, internal, classroom or other instructional use, on condition that the foregoing copyright notice is used so as to give reasonable notice of the Society’s copyright. This consent for free limited copying without prior consent of the Society does not extend to making copies for general distribution, for advertising or promotional purposes, for inclusion in new collective works or for resale. Abstract There is a common belief that it would be a universal good to discover how to slow or stop the aging process in humans. It guides the research of many biogerontologists, the course of some health policy leaders and the hopes of a substantial fraction of humanity. Yet, the outcome of achieving this goal is rarely addressed despite the fact that it would have profound consequences that would affect virtually every human institution. In this essay, I discuss the impact on human life if a means were found to slow our aging process, thus permitting a life expectancy suggested by the title of this conference, “Living to 100.” It is my belief that most of the consequences would not benefit either the individual or society. -
New England Centenarian Study Updates Medical Campus: We Hope This Newsletter Finds You and Your Family Well
Our contact November 2017 information at the Boston University New England Centenarian Study Updates Medical Campus: We hope this newsletter finds you and your family well. We’ve been The New England quite busy since our last newsletter with conferences, new research Centenarian Study publications, new participants, and new research partnerships as well as Boston University some staff changes to tell you about. We deeply value your help with Medical Campus our studies ,and to our participants, obviously none of what we do 88 East Newton Street would be possible without you! Robinson 2400 Boston, MA 02118 Our Toll-free Number: 888-333-6327 Pennsylvania, who is also the sec- ond oldest person ever in the world! Thomas T. Perls, MD, Of special note, we also enrolled MPH Sarah’s daughter Kitty at the age of 617‐638‐6688 Email: [email protected] 99 years and Kitty herself went on to become a centenarian. Stacy Andersen, PhD 617‐638‐6679 Sisters Mildred MacIsaac & Agnes Buckley, ages of 100 years and 103 Email: [email protected] years, were kind enough to pose for a photo shoot for Boston Julia Drury, BS Magazine which highlighted the 617-638-6675 Study’s recent findings Email: [email protected] Study Participant Recruitment Sara Sidlowski, BS Since beginning our research in 617-638-6683 Sarah Knauss, seated on the left, as 1996, we have enrolled approxi- Email: [email protected] the second oldest ever person in mately 2,500 centenarians includ- the world at age 119 years. Sarah is ing 150 supercentenarians (people the oldest participant in the New England Centenarian study. -
Khiḍr in the Interpretation of Sūrah Al-Kahf Verse 60-85
CHAPTER II MYTHOLOGY1 OF KHID{R IN ISLAM A. The description of Khid}r in Religious Literature We may be thinking, what God's purpose by creating all impossibility in a state of human knowledge about why the world is filled with something that not same, about the degree, human life and individual selfhood? Oftentimes we see something that is not reasonable and therefore all the fascination will always be born. Khid}r is always identified as the mysterious figure. Therefore, since the first until now is still repeatedly raised questions about his whereabouts, whether he is a prophet or guardian (wali<), whether he is alive or dead, whether he is the child of Adam or never had a father or a mother, and so on. Need to understand about figure of Khid}r, directly proportional to our belief that Khid}r is form one of the prophets of God that must be believed by all Musli<ms. This role is important, because it deals with the strengthening of our faith, because confidence will dismiss any confusion. We might be asked about the people who should we believe when we never know how that person has, and why should we believe and what impact will we get. a) Controversy about Descent and Biographical Data of Khid}r There is no mention of any agreement on the truth of the figure of Khid}r, Ibnu ‗Abbās said his real name is Balya bin Malka>n bin Fali<gh bin 1 The term mythology can refer either to a collection of myths (a mythos, e.g., Inca mythology) or to the study of myths (e.g., comparative mythology). -
Nebraska's 37 Supercentenarians Validated Among World's Longest-Lived
Nebraska’s 37 Supercentenarians Validated Among World’s Longest-Lived by E. A. Kral Updated Oct. 3, 2018 Since publication of the author's 44-page supplement "Nebraska's Centenarians Age 107 Or Above--1867 to 2001" in the April 24, 2002, Crete News and follow-up article on the state's supercentenarians published in the October 2, 2002, Crete News, more longevity claims have been validated for persons who have Nebraska connections by birth or by residence and have reached age 110 or above. For validation of longevity claims, three records are usually needed from the first 20 years of a person's life, including such sources as birth registration, baptismal record, census data, or marriage certificate. The author was able to validate--with assistance from Gerontology Research Group scholars and volunteers--all the individual supercentenarian reports that follow, along with a brief summary for each. Clara Herling Huhn (1887-2000) Born near Clarkson, Colfax County, she died at La Mesa, California at the age of 113 years and 327 days. She lived the first 51 years of her life in Colfax County, and is the longest-lived Nebraska native. To date, she is the oldest person in Nebraska history, and as of March 2012, she ranked among the top 100 oldest persons in world history, according to Gerontology Research Group based in Los Angeles. Ella Winkelmann Schuler (1897 - 2011) Born near Fontanelle, Washington County, Nebraska, she died at Topeka, Kansas at the age of 113 years and 244 days. She moved to Hooper, Dodge County in 1917, where she was married in 1923, then lived near Denver, Colorado and Page City, Thomas County, Kansas until 1934, when she relocated to Topeka. -
Contentual Study Between Amir Khosrow Dehlavi's Khamse and Nezami Ganjavi's Khamse
University College of Takestan Available online at http://UCTjournals.com Iranian Journal of Social Sciences and Humanities Research UCT . J. Soc. Scien. Human. Resear.(UJSSHR) Volume 1,Issue 1 01-06 (2014) ISSN:2382-9753 X Contentual study between Amir Khosrow Dehlavi's khamse and Nezami Ganjavi's Khamse Mahnaz Bayat 1 , Mahmood Tawoosi 2, Mahdi Mahoozi 3 1. Ph . D student of Persian Language and Literature , Roudehen Branch ,Islamic Azad university , Roudehen , Iran . 2. Professor of Persian Language and Literature ,Roudehen Branch , Islamic Azad university , Rodehen, Iran . 3. Professor and manager of Ph .D group of Persian Language and literature , Roudehen Branch, Islamic Azad university ,Rodehen , Iran. ABSTRACT Original Article: Amir Khosrow Dehlavi as one of the greatest and the most successful followers of Nezami's Khamse in the Indian Subcontinent is narrator of Nezami's stories and words or he could creat different work to Nezami's Khamse with his taste and creativity? A look at the content of Amir Khosrow's Khamse and Nezami's Khamse shows that Received 5 Aug. 2014 although Amir Khosrow has repeated many images and themes of Nezami in his Khamse but sometimes with Accepted 18 Sep. 2014 his poetical taste and artistic creativity has related some parts of his Masnavis different to Nezami's Khamse . Therefore his khamse in addition to that shows the colour of imitation of Nezami , is indicative of Published 21 Dec. 2014 artistry and creativity of the poet in creating attractive and enjoyable images . Keywords: Nezami Ganjavi , Amir Khosrow Dehlavi , Khamse , Content but a look at his Khamse shows that he has repeated many themes 1.