Design of Medical Devices Confeference

The Commons Hotel & McNamara Alumni Center Minneapolis, MN Welcome to the 13th Annual University of Minnesota Design of Medical Devices Conference

The Design of Medical Devices Conference was created in 2001 to enhance collaboration between academia and industry, promote policy, research and educational initiatives as they relate to medical device design and to support medical devices education at the University of Minnesota. This forum, uniquely positioned in the middle of one of the most significant medical device communities in the world, has provided invaluable insight and leadership to promote the future of this evolving industry. Conference attendance has more than tripled since its inception and we look forward to continued growth. The success of this conference is due in large part to the continued support from our industry sponsors and University of Minnesota partners. On behalf of the DMD Planning Committee, we thank you. We hope you enjoy this year’s conference!

Sincerely, Arthur Erdman, PhD William Durfee, PhD Paul Iaizzo, PhD Matthew Johnson, PhD Conference Chair Conference Co-Chair Conference Co-Chair Contributed Papers Chair Just Herder, PhD Saurav Paul, PhD Maura Donovan, PhD John Bischof, PhD Contributed Papers Co-Chair Conference Co-Chair Conference Co-Chair Conference Co-Chair

The Design of Medical Devices Conference is presented by the University of Minnesota Medical Devices Center (part of the Institute for Engineering in ), the College of Science and Engineering and the Department of Mechanical Engineering. In Cooperation with the Office of University Economic Development, University of Minnesota.

Connecting to the Wireless Network The Commons Hotel McNamara Alumni Center Commons Convention UofM Guest case-sensitive password: DMD2014 For technical assistance call 612-362-6662

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“BECOMING A MEDICAL THANK YOU TECHNOLOGY INNOVATOR” to all the participants of MEDICAL DEVICE INNOVATION WORKSHOP the 2014 5K Fun Run/Walk

Monday, April 7, 6:30 p.m. We want to thank all attendees who University of Minnesota participated in the 2014 Medical Device Start/Finish Line: Coffman Memorial Union

Innovation Pre-conference Workshop! The University of Minnesota 2013-2014 Medical Devices Center Innovation Fellows and 2014 Design of Medical Devices Special thanks to the 2014 presenters Conference would like to thank the participants and sponsors of • Susan Alpert, University of Minnesota • this years 5K Fun Run/Walk held Monday, April 7. • William Durfee, University of Minnesota • • Mike Finch, University of Minnesota • Please join us next year for the Seventh Annual 5K Fun Run/Walk • Michael Hoey, NxThera Inc. • Monday, April 13, 2015 on the University of Minnesota Campus. • Paul Iaizzo, University of Minnesota • Special thanks to the 5K sponsors • Barry Kudrowitz, University of Minnesota • • Design Soultions, Inc. • • Tim Laske, Medtronic AF Solutions • • Minnetronix • • John Mack, Medtronic Structural Heart • • Schwegman, Lundberg, Woessner • • Chaim Lotan, Hadassah-Hebrew University Medical Center • • Donatelle • • Consultants • • Brooks Sports, Inc. • Save the Date for 2015 • Road ID • Medical Devices Innovation Workshop • Summit Brewing Co. • Monday, April 13, 2015 www.dmd.umn.edu/workshop.html www.dmd.umn.edu/5K.html Medical Device Innovation Workshop “Becoming a Medical Technology Innovator” Monday, April 7, 2014 | Mississippi Room | Coffman Memorial Union

7:00 a.m. Registration and Continental Breakfast Welcome and Introduction 7:45 a.m. Paul A. Iaizzo and William Durfee, University of Minnesota How New Medical Products are Developed 8:15 a.m. William Durfee, Mechanical Engineering, University of Minnesota Performing Market Assessments 9:00 a.m. Mike Finch, Acting Director, MILI Carlson School of Management, University of Minnesota Evaluating Your Medical Device Idea Using Bench Tests, Animal Tests and Clinical Trials 9:30 a.m. Paul A. Iaizzo, , IEM, University of Minnesota Global Markets for Medical Devices 10:15 a.m. Tim Laske, VP, Research and Business Development, Medtronic AF Solutions 10:45 a.m. Coffee Break (receive team assignment) Essentials of Creativity Barry Kudrowitz, School of Design, University of Minnesota 11:05 a.m. William Durfee, Mechanical Engineering, University of Minnesota Innovation Exercise 1: Generate an Idea 12:30 p.m. Lunch Medical Device Regulations 1:10 p.m. Susan Alpert, MILI Executive in Residence, University of Minnesota Protecting Your Intellectual Property Through Patents 1:50 p.m. William Durfee, Mechanical Engineering, University of Minnesota How to Build a Medical Device Company 2:30 p.m. Michael Hoey, Founder/CTO, NxThera, Inc. The Corporate View of Technology Assessments and Acquisitions 3:00 p.m. John Mack, VP, Business Development, Strategy & Healthcare Economics, Medtronic Structural Heart 3:30 p.m. Coffee Break 3:45 p.m. Innovation Exercise 2: Develop a New Med Tech Product 4:30 p.m. Team Presentations The Perspective of a Clinician-Innovator 5:00 p.m. Chaim Lotan, Heart Institute, Hadassah-Hebrew University Medical Center Panel Discussion: Med Tech Innovation 5:30 p.m. Panelists: John Mack, Michael Hoey, Tim Laske, Chiam Lotan 6:00 p.m. Adjourn

2014 Design of Medical Devices Conference www.dmd.umn.edu Additions to the 2014 Program Plenary Keynote Tuesday, April 8, 8:00-10:00, Meridian Ballrooms 3 & 4, The Commons Hotel Keynote Presentation: How Big Data and Cognitive Computing will Transform Healthcare Martin S. Kohn, Chief Medical Scientist at Jointly Health, former Chief Medical Scientist, Care Delivery Systems, IBM Research Ophthalmic Medical Devices Tuesday, April 8, 10:30-12:00, Meridian Ballroom 2, The Commons Hotel Speaker Change: Multimodal Imaging in Retinal Disease Adam Doherty, Manager, Customer Education & Training, Heidelberg Engineering, Inc.

Surgical Simulation Wednesday, April 10, 2:00-3:30, Ski-U-Mah, McNamara Alumni Center Talk Title Change: Clinical Requirements that Drive Implant Design for the Treatment of Skeletal Defects: Bedside to Bench and Back Michael Yaszemski, Mayo Clinic

Emerging Medical Innovation Valuation Competition Tuesday, April 8, 4:00-5:30, Meridian Ballrooms 3 & 4, The Commons Hotel Presenter Change: Robert Brooks, Hospital for Sick Children Erik Robinson, Sintact Medical Systems, LLC Coley Duncan, MMM William Wustenberg, Biospheres, Inc. Joshua Gafford, Harvard Biodesign Lab, Harvard University International Student Design Showcase Tuesday, April 8, 5:30-7:30, Heritage Gallery, McNamara Alumni Center Judges Panel: Kevin Anderson, University of Minnesota Jenna Iaizzo, University of Minnesota Russ Straate, University of Minnesota Ben Arcand, University of Minnesota Alec Johnson, St. Thomas University Jack Stubbs, University of Minnesota Dana Boyle, Consultant Scott Mark, Medtronic, Inc. Alena Talkachova, University of Minnesota Jim Fairman, QFO Labs Laura Paulsen, University of Minnesota David Wood, University of Minnesota Danny Gelfman, Medtronic, Inc. 17. Bubble Bilevel Positive Airway Pressure (BiPAP) Device for the Developing World Patrick Hallal, Trevor Hudson, Jaewoo Park, and Jack Smith, Department of Bioengineering, Rice University

LIVE SURGERY - TIME CHANGE Wednesday, April 9, 10:00-12:00, A.I. Johnson Great Room, McNamara Alumni Center Check the web for details about the surgery, surgeon and moderator.

Cardiovascular 4: Pre-Clinical Trials for Cardiac Devices - LOCATION CHANGE Wednesday, April 9, 10:30-12:00,Meridian Ballrooms 3 & 4, The Commons Hotel

Global Health - LOCATION CHANGE Wednesday, April 9, 10:30-12:00, Maroon & Gold, McNamara Alumni Center

Technology Needs for Geriatric Care - TIME & LOCATION CHANGE Wednesday, April 9, 2:00-3:30, A.I Johnson Great Room, McNamara Alumni Cente Symposium Keynote Thursday, April 10, 10:00-11:45, Meridian Ballrooms 2 - 4, The Commons Hotel 2014 Design of Medical Devices Conference Keynote Presentation: Engineering the Future of Healthcare with Simulation Steve Levine, Sr. Director of Product Strategy, Dassault Systèmes SIMULIA Corp. Tuesday, April 8, 2014

7:00 a.m. The Commons Hotel MEDICAL DEVICE FELLOWS PROGRAMS NEUROENGINEERING 2 continued Registration and Continental Breakfast Maroon & Gold Room Session Organizers: McNamara Alumni Center Modulation of Neural Network Excitability with an 8:00 a.m. Meridian Ballrooms 1-4 Saurav Paul, University of Minnesota Implantable Closed-loop DBS System The Commons Hotel Ben Arcand, University of Minnesota Jon Giftakis Conference Welcome and Plenary Session Tuning your Innovation Strategy to the Call of Time Medtronic Neuromodulation FLUID POWER MEDICAL DEVICES Moderators: Avi Roop Arthur Erdman, Conference Chair Miret Surgical Meridian Ballroom 2 Session Organizer: The Commons Hotel William Durfee, Conference Co-Chair A Global Approach to Affordable Medical Device Elizabeth Hsiao-Wecksler, University of Illinois at How Big Data and Cognitive Computing will Urbana-Champaign Innovation Transform Healthcare Soumyadipta Acharya Precision Pneumatic, Concentric Tube Robot for Martin S. Kohn Johns Hopkins Hippocampal Ablation Care Delivery Systems, IBM Research David Comber Meridian Foyer, The Commons Hotel Pediatric Surgical Innovation – The Children’s Story Vanderbilt University 10:00 a.m. - 10:30 a.m. Axel Krieger SPONSOR EXHIBIT SHOWCASE Sheikh Zayed Institute for Pediatric Surgical Design of MRI-compatible Hemiparesis Innovation Rehabilitation Device 10:30 a.m. - 12:00 p.m. Lauren Lacey Concurrent Technical Sessions Bridging Points of Contention in University- Georgia Institute of Technology NEUROENGINEERING 1: NEUROIMAGING Industry Licensing Deals from an IP Perspective A Pneumatic Portable Powered Ankle-foot Orthosis Meridian Ballroom 1 Dinesh Melwani Session Organizer: The Commons Hotel Bookoff McAndrews for Gait Assistance Taner Akkin, University of Minnesota Elizabeth Hsiao-Wecksler Collaborative Approach to Securing Global Patents University of Illinois at Urbana-Champaign Spatiotemporal Encoding: A Way to Drastically Jay Erstling Reduce the Cost of MRI Patterson Thuente IP Fluid Powered Medical Devices via Additive Michael Garwood BIOMATERIALS Manufacturing University of Minnesota Ski-U-Mah Vito Gervasi Session Organizers: McNamara Alumni Center Milwaukee School of Engineering Optical Imaging of Brain Cancer Progression Peter Edelman, Boston Scientific Corporation CARDIOVASCULAR 2: ENGINEERED David Odde Wei Shen, University of Minnesota TISSUES FOR CARDIAC DEVICES University of Minnesota Materials Design for Cardiovascular Tissue Meridian Ballroom 3 & 4 Spatial Degree of Confinement Triggers Distinct Engineering and Intervention in Cardiovascular Session Organizer: The Commons Hotel Modes of GBM Cell Migration Tissue Remodeling Bob Tranquillo, University of Minnesota Digant Dave William Wagner Homologous “off-the-shelf ” Tissue Engineered Heart University of Texas at Arlington University of Pittsburgh Valves OPHTHALMIC MEDICAL DEVICES Clinical Requirements that Drive Implant Design for Frank Baaijens Meridian Ballroom 2 the Treatment of Skeletal Defects Eindhoven University of Technology Session Organizer: The Commons Hotel Michael Yaszemski Erik van Kuijk, University of Minnesota Mayo Clinic Tubular Heart Valves Based on Engineered Tissue Tubes Automating the Eye Exam with Binocular OCT Cardiac Tissue-inspired Extracellular Matrix Zeeshan Syedain Alexander Walsh (ECM)-based Scaffolds University of Minnesota Envision Diagnostics, Inc. Brenda Ogle Design of a Tissue Engineered Heart Valve with Image-based Biomarkers in the Retina: Applications University of Minnesota Potential for Remodeling, Growth, and Repair & Implications for Age-related Macular Degeneration Biocomptability & Invivo Biostability of Brandon Tefft Adam Boretsky Polysiobutylene based Polyurethanes Mayo Clinic University of Texas Medical Branch Kasyap Seethamraju HUMAN FACTORS 2: USABILITY OF 3D Boston Scientific Corporation Multimodal Imaging in Retinal Disease PRINTED MEDICAL DEVICES 12:15 p.m. Memorial Hall A.I Johnson Great Room Stephen Travers McNamara Alumni Center Heidelberg Engineering Session Organizer: McNamara Alumni Center Keynote Luncheon Richard Stein, Starkey Hearing Technologies CARDIOVASCULAR 1: CARDIAC Sponsored by Medtronic, Inc. KEYNOTE PRESENTATIONS Selected Case Studies of 3D Printed Medical Devices Meridian Ballrooms 3 & 4 Moderator: Paul Iaizzo, Conference Co-Chair James Orrock Session Organizer: The Commons Hotel Medical Technology Innovation in Israel, the Stratasys, Inc. Paul Iaizzo, University of Minnesota Start-up Nation Bioprinted Tissue Systems for Preclinical Clinical Implementation and Research of Chaim Lotan Applications Normothermic Organ Preservation in Thoracic Heart Institute Hadassah-Hebrew Benjamin Shepherd University Medical Center, Israel Heart Organovo, Inc. Gabriel Loor Society University of Minnesota 2:00 p.m. - 3:30 p.m. 3D Printing of Biologic Organs Cardiac Electrophysiology: an Historical Perspective Concurrent Technical Sessions Stuart Williams Boaz Avitall NEUROENGINEERING 2: NEURON University of Louisville University of Illinois Chicago MODULATION FOR EPILEPSY DRUG DELIVERY DEVICES Ski-U-Mah HUMAN FACTORS 1 Meridian Ballroom 1 Session Organizer: McNamara Alumni Center A.I. Johnson Great Room Session Organizer: The Commons Hotel Ronald Siegel, University of Minnesota Session Organizer: McNamara Alumni Center Tay Netoff, University of Minnesota Kathleen Harder, University of Minnesota A Long Time Coming: The Future Treatment of Epilepsy The Art of Falling Apart: Exploiting Nanomaterial Panel Discussion: How to Integrate Human Factors David Darrow Disassembly into your Product Development Process University of Minnesota Adah Almutairi Serge Dubeau University of California at San Diego Worrell, Inc. Where you need it, When you need it: On-demand Optogenetics for Temporal Lobe Epilepsy Savannah Sleicher Esther Krook-Magnuson Worrell, Inc. University of California, Irvine 4 order of presentations may vary, reference the online program for presentation details Tuesday, April 8, 2014

DRUG DELIVERY DEVICES continued CARDIOVASCULAR 3: CARDIAC LEAD INTERNATIONAL STUDENT DESIGN EXTRACTION SHOWCASE Poster Presenters Magnetic Nanoparticles for Pulmonary Drug A.I. Johnson Great Hall Delivery Session Organizers: McNamara Alumni Center 1. Shape Deposition Manufacturing of a Deployable Timothy Wiedmann Michael Eggen, Medtronic, Inc. Atraumatic Grasper for Minimally-invasive Surgery University of Minnesota Rick McVenes, Medtronic, Inc. Joshua Gafford, Ye Ding, Andrew Harris, Terrence McKenna, Panos Polygerinos, and Donal Holland, Pro-drug Approach to Intranasal Delivery of Rapid Clinical State of the Art for Lead Extraction Harvard University; A.J. Moser, Beth Israel Deconess Acting Antiepileptic Benzodiazepines Pierce Vatterott Medical Center; Conor Walsh, Harvard University Mamta Kapoor University of Minnesota 2. Reperfusion Balloon Catheter University of Minnesota Jessi Dinan and John Lewis, University of Cincinnati; Cardiac Lead Extraction, an Engineering Perspective Andrew Ringer, University of Cincinnati Meridian Foyer, The Commons Hotel Mark Marshall 3. Design of Thermoelectric Cooling Device for 3:30 p.m. - 4:00 p.m. Medtronic, Inc. Cryotherapy SPONSOR EXHIBIT SHOWCASE Karl Dedow, Linsey Nguy, Natalia Mejia, and Patrick Principles of Left Ventricular Lead Extraction Sullivan, The University of Texas at Austin 4:00 p.m. - 5:30 p.m. Stuart Adler 4. Cervical Spine Immobilization Device for Health East Heart Care Emergency Response Concurrent Technical Sessions Alperen Degirmenci, Benjamin Goldberg, Lukas BIG DATA - BRIDGING MEDICAL DEVICE PROSTHETICS & ORTHOTICS Bielskis, Shanna Wiggins, Panagiotis Polygerinos, DESIGN & HEALTHCARE DELIVERY: Donald Holland, Sophia Dyer, and Conor Walsh, Meridian Ballroom 1 CHANGING BEHAVIORS Harvard University Session Organizer: The Commons Hotel Andrew Hansen, University of Minnesota Maroon & Gold Room 5. An Embedded System Approach for Scanning Session Organizer: McNamara Alumni Center Near Infrared Spectroscope The 5 C’s of Prosthetic and Orthotic Development Greg Peterson, University of Minnesota Kuan-Cheng Wu and Kang Yu Chu, National Cheng Edward Lemaire Moderator: Kung University; Shou-I Chen, National Applied Research Laboratories; Jia-Jin Jason Chen, National University of Ottawa Claudia Neuhauser, University of Minnesota Cheng Kung University, National Applied Research Laboratories Bionic Ankle Prosthesis, Odyssey, Fully Powers Big Data, Medical Devices, and Healthcare Delivery Amputee Gait for Walking and Running Claudia Neuhauser 6. ChemoSeal: A Closed System Transfer Device for University of Minnesota the Developing World Jeffrey Ward Emily Augustini, Anam Azimuddin, Katerina SpringActive, Inc. Design by Dragging: A Next-Generation Software Kaczmarski, Nathan Jang, Jiwon Jung, Chen Wu, Eric Rchardson, and Maria Oden, Rice University; Ankle-foot Prostheses for Improved Balance and Tool for Data-intensive Design of Medical Devices Alicia Malbin, Becton Dickinson Stability during Standing and Slope Walking Dane Coffey 7. Lamprey-EX: A Bio-inspired Atherectomy Device Andrew Hansen University of Minnesota for More Effective Plaque Removal University of Minnesota Brittany Ferry, Chad Mohammed, and James Using Large Claims Databases to Analyze the Effect COMPUTATIONAL SPINE BIOMECHANICS Schumacher, University of Florida of and Hospital Market Structure on Meridian Ballroom 2 8. Intravascular Oximeter for Peripheral Artery Session Organizers: The Commons Hotel Medical Technology Diffusion Eric Dinges, Ellen Gardner, Kevin Johnson, and Elizabeth Winter, Univesity of Iowa Galyna Loughran, Zimmer Spine Pinar Karaca-Mandic Jeff Bischoff, Zimmer University of Minnesota 9. Contact-Free Vital Signs Monitoring System for Joan Bechtold, HCMC Premature Infants Moving from Prototype to Practice: Engineering Joshua Chartier, Hasitha Dharmasiri, Kiefer Forseth, Computational Wear Analysis of Intervertebral Disc the Application of Big Data into Modern Clinical Thomas Ladd, and Andrew Jones, Rice University Replacements Practice 10. Real-time Monitoring of Endotracheal Tubes Curt Goreham Voss Following Neonatal Intubation Kevin Peterson Dan Coughlin, Lynn Dinh, Ropo Oke, Sneha Somani, Medtronic, Inc. University of Minnesota Uyen Truong, and Kristen Watermolen, University of Minnesota Novel Spine Device Development: Complementing COLLABORATIVE DESIGN OF MEDICAL Empirical Testing with Numerical Evaluation DEVICES 11. Smart Myoelectric Prosthetic Arm Ski-U-Mah Sherif Elbasiouny, Renee Langhals, Michael-Josef Mike Dahl Session Organizer: McNamara Alumni Center Bernards, Andrew Clark, Nourhan Abouzahra, Medical Device Consultant Mary Beth Privitera, University of Cincinnati Wright State University Developing a Global Human Factors Process 12. DeXcellence: A Quantitative Evaluation Tool for Industry Perspective of Role of Computational Pediatric Patients with Cerebral Palsy Modeling of Spinal Devices Nancy Bayer Allison Garza, Andrew Schober, Shaurya Agarwal, Galyna Loughran Smiths Medical Sonia Garcia, and Vivas Kumar, Rice University Zimmer Spine Jennifer Tsai 13. AntiBody: A Simulator to Allow Experiments Smiths Medical to be Undertaken on Mechanically Accurate Bone EMERGING MEDICAL INNOVATION Geometry, with a Aimulated Circulatory System to VALUATION COMPETITION The Human Factor – Going From a Blank Slate to Allow Cell Growth, Adhesion, and Infection Meridian Ballroom 3 & 4 Validated Concepts Using Human Needs Andrew Dalman, Lucas Budzien, Joel Hedlof, Session Organizers: The Commons Hotel Michael Tchida, Dustin Mueller, Jake Larson, and Alison Bagwell Mike Finch, University of Minnesota Cong Liu, North Dakota State University Kimberly-Clark Health Care Randy Nelson, Evergreen Medical Technologies 14. BiliQuant: A Spectrophotometric Jaundice Joe Cesa Diagnostic for the Developing World Presenters: Kimberly-Clark Health Care Stephanie Tzouanas, Melody Tan, Jacinta Leyden, Coley Duncan Monica Barrera, Roham Shah, Meaghan Bond, Eric MMM Jump-starting Early Phase Development Through Richardson, Maria Oden, and Rebecca Richards- Krishanu Nandy Focused Collaboration Kortum, Rice University Northwestern University David Copeland 15. Electromyography-based Seizure Detection Joshua Gafford Ximedica Device Chia-Ye Chu, Michael Lam, Kyung Taeck Minn, Alex Harvard University 5:30 p.m. - 7:30 p.m. Heritage Gallery Yang, and Olyver Yau, Rice University Cyrus Munshi McNamara Alumni Center Biospheres, Inc. 16. Air Retention Device for Colonoscopy Procedures INTERNATIONAL STUDENT DESIGN Michael McEniry, Ross Oborny, and Lauren Glett, Robert Brooks SHOWCASE University of Nebraska-Lincoln Hospital for Sick Children 17. Bubble Bilevel Positive Airway Pressure (BiPAP) The purpose of this showcase is to promote and Device for the Developing World Judges: publicize excellence in medical device design by Holly Liang, Caitlin Makatura, Mike Schubert, Bryan Mike Finch, University of Minnesota teams of undergraduate and graduate students Soloman, and Julie Walker, Rice University Karen Kaehler, University of Minnesota conducted as part of their course work. Paul Gam, Zurich Medical Teams are competing for one of three cash prizes: 7:30 p.m. ADJOURN Randy Nelson, University of Minnesota $500, $300, and $200. order of presentations may vary, reference the online program for presentation details order of presentations may vary, reference the online program for presentation details 5 Wednesday, April 9, 2014 MEDICAL MICRO & NANO SYSTEMS continued TECHNOLOGY NEEDS FOR GERIATRIC CARE Maroon & Gold Room Micro-transducers Enabled Advanced Intravascular ® Session Organizer: McNamara Alumni Center 30 Years of Leadership Ultrasound Imaging Jean Wyman, University of Minnesota Xiaoning Jiang Leading the conversation. North Carolina State University Health-based Technology for Older Adults Jean Wyman www.LifeScienceAlley.org Microflotronics: Wearable, Flexible, Transparent University of Minnesota Pressure-sensitive Devices for Mobile Health 7:00 a.m. Meridian Ballrooms 2-4, The Commons Hotel Tingrui Pan Proactive Health Management using In-home Registration and Networking Breakfast University of California, Davis Sensing and Recognition Technology hosted by LifeScience Alley Marjorie Skubic CMOS ISFET Sensor Array with Catalytic 8:00 a.m. Meridian Ballrooms 2-4 University of Missouri-Columbia The Commons Hotel Chemical Vapor Deposited Silicon Nitride Layer and Its Medical Application Technology-enhanced Solutions for Enhanced Senior THREE-IN-FIVE COMPETITION Shota Sando Care Experiences Moderators: Nagoya University Bryan Fuhr Jesús Cabrera, University of Minnesota Healthsense, Inc. Just Herder, Delft University of Technology SURGICAL ROBOTICS & COMPUTATIONAL SURGERY Can Wearable Technology Improve Balance, Monolithic Fabrication of Millimeter-Scale Surgical Mobility, and Decrease Falls? Devices with Integrated Sensing Meridian Ballrooms 2 Session Organizer: The Commons Hotel Lars Oddsson Joshua Gafford, Harvard University Timothy Kowalewski, University of Minnesota Courage Kenny Rehabilitation Institute A Supine Gait Training Device for Stroke Computational Modeling and Enhancement of IMAGE-GUIDED INTERVENTIONS Rehabilitation Human Skill Ski-U-Mah Fang Ming Lim, National University of Gregory Hager Session Organizer: McNamara Alumni Center Signapore Johns Hopkins University Emad Ebbini, University of Minnesota Acoustic Radiation Force Impulse (ARFI) Imaging Mobility-enhancing Fall-prevention Device for Practical Limitations of Modern Urologic Robotic Guidance of Cardiac Ablation Physical Rehabilitation Surgery Gregg Trahey Carl Nelson, University of Nebraska-Lincoln Kyle Anderson Duke University Biologically Inspired Soft Robot for Thumb University of Minnesota Image Guided Visualization of RF/Microwave Ablations Rehabilitation Surgical Robots for within the Wider using Applicator Perturbation for Elasticity Imaging Paxton Maeder-York, Harvard University OR Ecosystem Tomy Varghese Meir Dahan Automated Fluorescence Microscope for Tuberculosis University of Wisconsin - Madison Detection IMRIS, Inc. Kylie de Jager, University of Cape Town Dual-mode Ultrasound Array (DMUA) Systems for Automated Error-avoidance for Surgical Robots Image-guided Vascular Interventions Timothy Kowalewski Printing Strain Gauges on Surgical Instruments for Emad Ebbini Force Measurement University of Minnesota University of Minnesota Frank Hammond, III, Harvard University GLOBAL HEALTH 12:15 p.m. Memorial Hall Meridian Ballrooms 3 & 4 Biomimetic Attachment to the Gastrointestinal Tract McNamara Alumni Center Session Organizer: The Commons Hotel Wanchuan Xie, University of Nebraska- Lincoln John Bischof, University of Minnesota KEYNOTE & AWARDS LUNCHEON Automated Sample Preparation for Microscopy-based Sponsored by Boston Scientific Corporation New Pedicle Screw Design with Expandable Shell for Malaria Diagnostics Low Bone Quality Kevin Nichols Moderator: Teyfik Demir, University of Economics & Intellectual Ventures Laboratory Arthur Erdman, University of Minnesota Technology Presentation of the Emerging Medical Innovation Quantum Dot Barcodes for Multiplex Infectious Innovative Sutureless Microvascular Anastomotic Valuation Competition Awards by Randy Nelson, Disease Diagnostics Device with Embedded Doppler Flow Monitoring President, Evergreen Medical Technologies Warren Chan Tracy Konobeck, Synovis Life Technologies Recipient of the 2014 Design of Medical University of Toronto Devices Conference Award Disposable Fluidic Self-propelling Robot for Colonoscopy Thermal Contrast for Improved Lateral Flow Assays Towards the Essence in Medical Device Design Sina Pourghodrat, University of Nebraska- David Boulware Just Herder Lincoln University of Minnesota Delft University of Technology CARDIOVASCULAR 4: PRE-CLINICAL (Keynote lunches are a separate billable event, meal tickets are required.) Judges: TRIALS FOR CARDIAC DEVICES Micheal Hoey, NxThera, Inc. A.I Johnson Great Room 2:00 p.m. - 3:30 p.m. Mike Finch, University of Minnesota Session Organizer: McNamara Alumni Center Concurrent Technical Sessions Tim Laske, Medtronic, Inc. Paul Iaizzo, University of Minnesota Ross Meisner, Dymedex Consulting, LLC NEUROENGINEERING 3: PERIPHERAL Dan Sachs, DSVentures The Evolution of Interventional Translational NERVE STIMULATION Jack Stubbs, University of Minnesota Science: The Backbone of ALL Current and Future Meridian Ballroom 1 Randy Schiestl, Boston Scientific Corporation Catheter Based Session Organizer: The Commons Hotel Juan Granada Meridian Foyer, The Commons Hotel Matthew Johnson, University of Minnesota CRF-Skirball Center for Cardiovascular Autonomic Modulation : Vagus Nerve 10:00 a.m. - 10:30 a.m. Research SPONSOR EXHIBIT SHOWCASE Stimulation for Heart Failure The Future of Computational Modeling for the Pre- Juan Hincapie 10:30 a.m. - 12:00 p.m. clinical Assesment of Cardiac Devices Boston Scientific Corporation Concurrent Technical Sessions Dawn Bardot Blockade of Axonal Conduction through Vagus MEDICAL MICRO & NANO SYSTEMS Medical Device Innovation Consortium Nerve using High Frequency Alternating Current Meridian Ballroom 1 Getting to the Heart of Preclinical Device Analysis Christopher Honda Session Organizer: The Commons Hotel Nicholas Robinson University of Minnesota Tianhong Cui, University of Minnesota University of Minnesota Neuromodulation on Bladder Capacity in Conscious High Sensitivity, Quantitative Detection of Sheep Chemotherapy Induced Neuropathy Xin Su William Kennedy Medtronic, Inc. University of Minnesota 6 order of presentations may vary, reference the online program for presentation details Wednesday, April 9, 2014 CATHETER ROBOTICS DEVICES FOR DEVELOPING NATIONS: CARDIOVASCULAR 6: ADVANCES IN Meridian Ballroom 2 EXAMPLES OF LOW COST HIGH IMPACT CARDIOVASCULAR TECHNOLOGY continued Session Organizer: The Commons Hotel PROJECTS FROM PEDIATRIC & ADULT Hao Su, Philips MEDICINE Augmented Reality for Improving Catheterization in MRI-guided Cardiac Electrophysiology Therapy Lesion Prediction and Estimation in RF Ablation of Ski-U-Mah Yue Chen Myocardial Tissue Session Organizer: McNamara Alumni Center University of Georgia Ilker Tunay Gwenyth Fischer, University of Minnesota Pediatric Critical Care Stereotaxis, Inc. Pacemaker and Defibrillator Lead Tip Interactions in Respiratory Support with Bubble CPAP in Children Porcine Cardiac Tissue and Tissue Substitute on the Bench Robotic Stent Placement during Coronary Intervention in Low Resource Areas Oleg Vesnovsky Tal Wenderow Ashley Bjorkland US Food and Drug Administration EVP Product & Business Development Amplatz Children’s Hospital ADVANCES IN SENSING SYSTEMS ON Minimally Invasive Robotic Catheters: Addressing Pocket Protocols: Advancing Mobile Technologies for MEDICAL DEVICES Challenges through Modeling, Control, and Design Newborn Health A.I Johnson Great Room Michael Zinn Session Organizer: McNamara Alumni Center Annamarie Saarinen Rajesh Rajamani, University of Minnesota University of Wisconsin - Madison Newborn Foundation | Coalition Low Power Analog-to-Digital Converters for Bio- MRI-guided Electrophysiological Catheter Therapy Health Stethoscope Screening for Heart Disease signal Sensing Zion Tse Lee Pyles Chris Kim University of Georgia University of Minnesota University of Minnesota CARDIOVASCULAR 5: PEDIATRIC Pouya Hemmati CARDIAC INNOVATION: THE NEXT University of Minnesota An Array of Highly Sensitive Micro Flexible Pressure Sensors for In-vivo Applications GENERATION Meridian Foyer, The Commons Hotel Meridian Ballrooms 3 & 4 Mahdi Ahmadi Session Organizer: The Commons Hotel 3:30 p.m. - 4:00 p.m. University of Minnesota James St. Louis, Amplatz Children’s Hospital SPONSOR EXHIBIT SHOWCASE Enabling Auscultation in High Noise Environments Innovations in Mechanical Circulatory Assist Devices 4:00 p.m. - 5:30 p.m. Garrett Nelson in the Pediatric Patient Concurrent Technical Sessions University of Minnesota Robroy MacIver NEUROENGINEERING 4: NOVEL MEDICAL DEVICE INNOVATION University of Minnesota APPROACHES FOR EXCITING OR Maroon & Gold Room The Ventricular Septal Defect, Non-surgical Closure in INHIBITING THE BRAIN Session Organizers: McNamara Alumni Center the Operating Room Meridian Ballroom 1 Saurav Paul, University of Minnesota John Bass Session Organizer: The Commons Hotel Ben Arand, University of Minnesota University of Minnesota Hugh Lim, University of Minnesota Medical Device Innovation for Global Healthcare - Safe Direct Current Neural Implant Its Evolution and Current Trends The Creation of a Virtual Congenital Cardiac Encyclopedia Gene Fridman Stacy Enxing Seng Johns Hopkins University Covidien Vascular Therapies Charles Shepard University of Minnesota Transcranial Focused Ultrasound for Localized Designing your Innovation Strategy in a Global Targeting of Brain Tissue Environment Surgical Options for the Failed Single Ventricle Emad Ebbini Michael Hoey Mark Plunkett University of Minnesota NxThera, Inc. University of Minnesota

LIVE SURGERY A.I Johnson Great Room A New Noninvasive Approach for Modulating the Innovation towards Affordable Healthcare through McNamara Alumni Center Brain Using Multimodal Pathways Greater Transparency Hubert Lim Jayant Parthasarathy A University of Minnesota surgeon will be performing a UnitedHealth Group minimally invasive surgical procedure at the University University of Minnesota of Minnesota -Fairview Hospital. The WEARABLE MEDICAL DEVICES SURGICAL SIMULATION surgery will be transmitted to the conference via live video Meridian Ballroom 2 Ski-U-Mah feed. A moderator will be at the conference explaining the Session Organizers: The Commons Hotel Session Organizers: McNamara Alumni Center procedure and passing questions from the audience along Lucy Dunne, University of Minnesota Timothy Kowalewski, University of Minnesota to the surgeon. The objective of the session is to discuss Lars Oddsson, Courage Kenny Rehabilitation Institute Rob Sweet, University of Minnesota the strengths, weaknesses and design opportunities for the tools and devices used in modern surgery. Advances in Manufacturing for Custom Wearable Devices Virtual Reality SIM Curriculum Increases Market Tom Stocco Penetration for a New Surgical Technology IMPLEMENTING SECURE WIRELESS Solaris Inc. Rob Sweet COMMUNICATION IN MEDICAL DEVICES University of Minnesota Advances in Wearable Medical Devices Maroon & Gold Room Yunhe Shen Session Organizers: McNamara Alumni Center Tony Riley University of Minnesota Keshab Parhi, University of Minnesota Medtronic, Inc. Leon Durivage, Minnetronix, Inc. Design of Walkasins - A Balance Sensory AMS-A Medical Device Company’s Interest in VR Emerging Regulations and Standards for Medical Augmentation and Substitution System Simulation Device Security Lars Oddsson Michael Kujak American Medical Systems Ken Hoyme Courage Kenny Rehabilitation Institute Adventium Labs CARDIOVASCULAR 6: ADVANCES IN 5:30 p.m. - 7:00 p.m. DQ Room, TCF Bank Stadium CARDIOVASCULAR TECHNOLOGY Designing Wireless Systems in Medical Devices – SCIENTIFIC POSTER SESSION Meridian Ballroom 3 & 4 Practical Applications, Limitations, and Tradeoffs Session Organizer: The Commons Hotel Enter through Premium Entrance under Benton Joe Bange Daniel Mooradian, University of Minnesota County on the SW side of TCF Bank Stadium Fellow Electrical Engineer Validation of Peripheral Pulse Wave Analysis Technique Shuttles available to and from The Commons Hotel to Detect Aortic Valve State in Continuous-flow LVADs A complete list of titles & authors are on pages 14-17. Security for Resource-constrained Medical Devices Ashish Singal TOUR OF THE TCF BANK STADIUM Chris Petersen University of Minnesota tours depart the DQ Room at 6:50 p.m., 7:00 p.m. & 7:10 p.m. Medtronic, Inc. (pre-registration required) Innovative Sutureless Microvascular Anastomotic Device with Embedded Doppler Flow Monitoring 7:00 p.m. ADJOURN Daniel Mooradian University of Minnesota order of presentations may vary, reference the online program for presentation details order of presentations may vary, reference the online program for presentation details 7 Thursday, April 10, 2014

7:00 a.m. The Commons Hotel 2:00 p.m. GUIDED TOURS Registration and Continental Breakfast “Regulatory Science” Symposium “Regulatory Science” 10:00 a.m. Meridian Ballrooms 2-4 Center for Research The Commons Hotel Education and Simulation Symposium Technologies (CREST) 8:00 a.m. Meridian Ballrooms 2-4 KEYNOTE ADDRESSES The Commons Hotel www.crest.umn.edu Verification, Validation, and the Social Negotiation WELCOME AND INTRODUCTION of Trust in Technology Characterization Facility Tina Morrison, Food and Drug Administration Laura A. McNamara (CharFac) Dawn Bardot, Medical Device Innovation Sandia National Laboratories www.charfac.umn.edu Consortium Enabling Medical Device Innovation through Experimental Surgical KEYNOTE ADDRESSES Regulatory Science Advancements Services (ESS) Michelle McMurry-Heath www.ess.umn.edu Food and Drug Administration What Does Regulatory Science Mean to Device Interactive Visualization Submission that Include Computational Modeling 10:00 a.m. - 11:45 a.m. Lab (IV Lab) and Simulation? Concurrent Technical Session www.ivlab.cs.umn.edu Tina Morrison ADVANCES IN MEDICAL DEVICES 2 Food and Drug Administration A.I Johnson Great Room Medical Devices Center How can Regulatory Science Help Medtech Session Organizer: McNamara Alumni Center (MDC) Innovators Matt Johnson, University of Minnesota www.mdc.umn.edu Moderator: Bill Murray Darrin Beekman, University of Minnesota Minnesota Nano Center Medical Device Innovation Consortium Neural Cells Show Higher Sensitivity to Irreversible (MNC) Regulatory Science Methods: The Medical Device Electroporation Compared to Cancer and www.mnc.umn.edu Development Tool Cardiovascular Cells The Visible Heart® Kathryn M. O’Callaghan Chunlan Jiang Laboratory (VH Lab) Food and Drug Administration University of Minnesota www.vhlab.umn.edu/atlas 8:00 a.m. - 9:30 a.m. EEG Electrode Configuration and Source Imaging See the ad on the next page for more Concurrent Technical Session Abbas Sohrabpour University of Minnesota information about the facilities, ADVANCES IN MEDICAL DEVICES 1 departure times and locations Automatic Instrument Tracking Endo-illuminator A.I Johnson Great Room 2:00 p.m. ADJOURN Session Organizer: McNamara Alumni Center for Intraocular Matt Johnson, University of Minnesota Ramiro Piñón Moderator: University of Michigan Neil Vaughan, Bournemouth University Fiber Optic Tissue Differentiation Using Diffuse Complete the DMD Heart Signal Abnormality Detection Using Artificial Reflectance: Towards an Active Surgical Feedback Neural Networks System Attendee Survey Md. Ali Haider Darrin Beekman University of North Dakota University of Minnesota by April 28, 2014! 12:00 p.m. Memorial Hall VR Simulation Based Assessment Objectives for McNamara Alumni Center Epidural Training Your input is greatly appreciated! Neil Vaughan LUNCHEON KEYNOTE AND AWARDS As a thank you for your participation, we Bournemouth University Sponsored by Burroughs Wellcome Fund will randomly drawing two names from the pool of those who have successfully High-speed Visualization of a Steam Pop during Moderator: Radiofrequency Ablation William Durfee, University of Minnesota submitted the survey. The prizes include: Stephen Quallich Dana Boyle, LifeScience Alley University of Minnesota (1) One Night Stay at The Commons Three-in-Five Awards Presented by Jesús Cabrera, Hotel, Minneapolis, MN An Intraventricular Soft Robotic Pulsatile Assist University of Minnesota and Just Herder, Delft Device For Right Ventricular Heart Failure University of Technology Nikolay Vasilyev (1) Complimentary Full Registration for Boston Children’s Hospital Honorary Recipient of the 2014 Woman in the 2015 DMD Conference MedTech Award Meridian Foyer, The Commons Hotel The winners will be chosen and notified 9:30 a.m. - 10:00 a.m. Device Innovation and Regulatory Science shortly after the survey closes. SPONSOR EXHIBIT SHOWCASE Ellen R. Strahlman BD (Keynote lunches are a separate billable event, meal tickets are required.) DESIGN OF MEDICAL DEVICES CONFERENCE

8 order of presentations may vary, reference the online program for presentation details GUIDED TOURS

Center for Research Education and Simulation Technologies (CREST) www.crest.umn.edu CREST is the associated research branch of SimPORTAL (Simulation PeriOperative Resource for Training and Learning), the simulation center for the University of Minnesota Medical School. The mission of CREST is to be a world leader in the research and development of novel curricula and simulation models to drive the future of healthcare professional education. At the heart of our simulation work is an innovative method for building accurate, 3D reconstructions of human anatomy. Using real patient MR and CT data as reference models, and cadaveric photography for accurate texturing, our lab can construct any organ system, catered specifically to any patient, condition, or surgical procedure. Our method allows us to build organ systems in a variety of resolutions, ranging from low end meshes ideal for volumetric simulation, to high end meshes used for photo realistic animation and illustration. We also have an artificial tissue lab with analogue models benchmarked against our human tissue database. CREST is also the host and for Live 3D visualization, recording, and streaming between the FV operating rooms, the Medical School and the Medical Devices Center.

Characterization Facility (CharFac) www.charfac.umn.edu The CharFac provides academic and industrial partners access to state-of-the-art characterization methods which measure material properties from the micron-to the sub-nanometer scale. Our staff has extensive experience with the materials characterization of medical devices using light, x-rays, scanning probe and electron beam methods. We do both open research and proprietary work, and can perform the experiments for you or train you on the use of our extensive instrumentation: scanning and transmission electron microscopes, x-ray scattering/diffraction, Raman and Infrared spectroscopy and microscopy, surface analytical along with an extensive range of atomic force microscopy and nano-indentation methods.

Experimental Surgical Services (ESS) www.ess.umn.edu At ESS, we are experts in designing and conducting the appropriate research to determine the safety and efficiency of medical devices. We have more than 25 years of experience in pre-clinical assessment for the medical industry. In fact, we are the industry leader in researching and testing cardiac devices and surgical techniques. We complete over 500 open heart procedures and over 1,500 procedures annually. ESS is Directed by Richard W. Bianco who has more than 25 years of experience in the pre-clinical assessment of virtually every animal model. The ESS staff of in-house surgeons work with device companies to develop and validate research methods, provide consultation as necessary and offer interpretative and technical support.

Interactive Visualization Lab (IV Lab) www.ivlab.cs.umn.edu IV Lab research involves data visualization, computer graphics, and human-computer interaction. Current projects include visualization of time- varying (motion) data, large-scale data visualization, perceptually optimized visualization, 3D user interfaces, haptics, and pen and multi-touch input techniques. Our work is supported by the National Science Foundation, National Academies Keck Futures Initiative, grants from industry, and the University of Minnesota. The research group includes about 10 undergraduate and graduate students. The IV Lab in Keller Hall is equipped with high-end graphics workstations that drive a series of innovative visual displays and interactive devices. Major equipment includes a Multi-Surface, Multi-Touch Virtual Reality Environment and a 3D Haptic (Force-Feedback) Display. We also work regularly with the visualization facilities at the Minnesota Supercomputing Institute.

Medical Devices Center (MDC) www.mdc.umn.edu The MDC at the University of Minnesota is a unique interdisciplinary program that resides within the Institute for Engineering in Medicine. The MDC aims to strengthen interdisciplinary research among faculty in the health sciences and engineering in areas specifically related to medical devices. The center trains the next generation of medical device inventors including( the Innovation Fellows Program) and fosters new relationships with the medical device industry and government agencies to improve health care worldwide. This tour will highlight the brand new 8,000 square ft. facility that is configured to promote interdisciplinary medical device development including needs assessment, creative brainstorming, prototyping and testing.

Additional Tour Times: Tuesday, April 9 and Wednesday, April 10 at 10:00 a.m. & 3:30 p.m., departing from The Commons Hotel Registration Desk

Minnesota Nano Center (MNC) www.mnc.umn.edu The MNC is a state-of-the-art facility for interdisciplinary research in nanoscience and applied nanotechnology. The center offersa comprehensive set of tools in two clean rooms for fabricating new micro- and nanoscale devices, such as integrated circuits, advanced sensors, and microfluidic systems. The MNC is also equipped to support nanotechnology research that spans many science and engineering fields, in areas as diverse as cell biology, high performance materials, and biomedical device engineering. This interdisciplinary work takes place in two new specialized labs to support interdisciplinary research in bio-nanotechnology and nano/micrometer-scale materials. Tour attendees will see the Nano Center’s new class 10 clean room and its fabrication tools, as well as our new applications labs devoted bio-nanotechnology and nanomaterials.

The Visible Heart® Laboratory (VH Lab) www.vhlab.umn.edu/atlas Dr. Paul Iaizzo has been at the University of Minnesota since 1990, performing research and teaching graduate and undergraduate courses. In 1997, Dr. Iaizzo and his coworkers created VH Lab in collaboration with Medtronic, Inc. Today, this lab is a premiere place to perform translational systems physiology research that ranges from cellular and tissue studies to organ and whole body investigations. The VH Lab also has a unique human heart library. The VH Lab embodies a creative atmosphere which is energized by some of the best and brightest students at the University. Our lab staff has over 100 years of collective research experience and functions as a highly efficient and productive team.

Tours are Thursday, April 10 at 2:00 p.m. and will depart from Memorial Hall, McNamara Alumni Center. Please sign-up at the conference registration desk before 12 p.m. on Thursday, April 10. 9 FEATURING EXHIBITS

A Heart to Learn

April 8-10, 8:00 a.m. - 4:00 p.m. Think 4, The Commons Hotel

This will be an interactive display of perfusion fixed human hearts courtesy of the Visible Heart Laboratory and the Department of Surgery. This is a unique library of human hearts received from organ donors and their families via LifeSource and the University of Minnesota’s Anatomy Bequest Program.

Perfusion fixation dilates these hearts as if they were filled with blood (diastole). Additionally, computer stations will be available to introduce The Atlas of Human Cardiac Anatomy and utilize during the display.

The Atlas of Human Cardiac Anatomy is an interactive educational site created and maintained by the Visible Heart® Laboratory at the University of Minnesota in collaboration with Medtronic, Inc. This site features images created from the Visible Heart® project, a novel educational tool which allows for viewing functional human cardiac anatomy from within. www.vhlab.umn.edu Simulation Technologies Suite April 8-10, 8:00 a.m. - 4:00 p.m. Think 5, The Commons Hotel

As the health care industry rapidly transforms, medical training at the University of Minnesota (UMN) isn’t satisfied just keeping pace. Through a unique collaboration with industry partners, the UMN is developing new surgical simulation tools with an unprecedented level of realism – better preparing medical professionals for real-world procedures and ultimately leading to better patient care. This will be an opportunity to have a hands on look at Simulation PeriOperative Resources for Training and Learning (SIMPORTAL), the UMN’s system for simulation equipment and clinical training, ensures medical professionals are up to par on procedures before they start operating on real patients.

SIMPORTAL’s researchers are now teaming up with the UMN’s Medical Devices Center and its Interactive Visualization Lab, combining resources from 3D modeling, interactive visualization and a one of a kind human tissue properties database to develop medical simulation tools that look and act like parts of the human body. The accomplishment would not have been possible without industry collaboration from partners like 7-SIGMA, Stratasys, Bose ElectroForce and Vital Images www.crest.umn.edu

10 MEDICAL DEVICES CENTER

The Medical Devices Center (MDC) at the University of Minnesota is an interdisciplinary program that sits within the Institute for Engineering in Medicine and combines basic research, applied and translational research, education and training, and outreach and public engagement all related to medical devices. The MDC brings together the University of Minnesota´s expertise from the College of Science and Engineering and the Academic Health Center (Colleges of Medicine, , , Nursing and ). The MDC provides a unique environment with extensive prototyping equipment, support staff and interface with the University of Minnesota Medical Center, Fairview. The center trains the next generation of medical device inventors and fosters new relationships with the medical device industry and government agencies to improve health care worldwide.

The MDC has many roles within the University of Minnesota including: Medical Devices Center • Train the next generation of innovators through the Innovative Fellows Program • Acceleration of interdisciplinary medical device Research and Development • Distribute funding for creation of new medical devices based on a peer review process • Focus on projects needing a boost to achieve national prominence and/or generate important Intellectual property • Create a Core Lab with common use equipment for creative prototypes • Facilitate connections to other Centers and Labs • Support U of M functions related to medical devices • Support the teaching/training programs of departments related to medical devices • Actively interface with the medical device industry MDC INNOVATION FELLOWS PROGRAM

INNOVATORS WANTED! Applications Now Being Accepted for the Medical Devices Center Innovation Fellows 2014-15 Team The University of Minnesota is recruiting a cross-disciplinary team for collaborative medical device innovation. Those encouraged to apply include: postgraduate engineers, experienced as well as those in their residency or fellowship training, bio-scientists, seasoned medical device professionals, business professionals, IP attorneys, medical practitioners and others with a special interest in medical device innovation. Applicants must be dedicated to improving human health and well-being. Successful candidates are self- driven and highly motivated individuals with entrepreneurial spirit and committed to working in a collaborative team setting. The University of Minnesota Medical Devices Innovation Fellows Program is sponsored by the University of Minnesota Medical Devices Center, part of the Institute for Engineering in Medicine and the College of Science & Engineering. The program already has seen much success with more than 100 invention disclosures and more than 50 patent applications filed on those inventions in the program’s first five years. Responsibilities: • Identifying clinical needs, inventing, and building & testing prototype solutions • Generating 15-20 patentable disclosures on medical devices for diagnosis and treatment • Working closely with clinicians at the University of Minnesota Academic Health Center and partnering with established medical device corporations Eligibility: • Degree in Engineering, Medicine, or Biosciences. Medical or Doctorate degrees preferred • Evidence of creativity and innovation • One or more years of research training Benefits: • Monthly salary and health benefits provided for the duration of the Fellowship • Use of first-class facilities in engineering & medicine at the University of Minnesota • Access to top MD’s, PhD’s, and innovators at the University of Minnesota and local industry How to Apply: For more information please see the Medical Devices Center website (www.mdc.umn.edu). Complete the online application, submit a cover letter, curriculum vitae, written essay, video, and two references. Positions will be filled on a rolling basis as qualified applicants apply. (Requisition number 189543)

- Application Deadline is Sunday, April 20, 2014 -

Please direct questions regarding this application process to [email protected] The University of Minnesota is committed to the policy that all persons shall have equal access to its programs, facilities, and employment without regard to race, color, creed, religion, national origin, sex, age, marital status, disability, public assistance status, veteran status, or sexual orientation.

11 Scientific Poster Session Wednesday, April 9, 5:30 p.m. - 7:00 p.m. DQ Room, TCF Bank Stadium

1. An Automated Intestinal Biomechanics Simulator for Expediting Robotic 18. Design and Fabrication of Prostrate Ring-scanning Equipment for NIR Capsule Endoscope Development2 Diffuse Optical Imaging2 Piotr Slawinski and Benjamin Terry, Department of Mechanical & Materials Jhao-Ming Yu, Department of Mechanical Engineering, National Central Engineering, University of Nebraska-Lincoln University; Min-Cheng Pan, Department of Electronic Engineering, Tung-Nan 2. Intracoronary Injection of Medication from Multi-lumen Injection University; Ya-Fen Hsu, Department of Surgery, Landseed Hospital; Liang-Yu Catheters1 Chen, Graduate Institute of Biomedical Engineering, National Central University; Brian Plourde, Dillon Schwalbach, and John Abraham, School of Engineering, Min-Chun Pan, Department of Mechanical Engineering, National Central University of St. Thomas; Rob Kohler, Translational Research Institute University, Graduate Institute of Biomedical Engineering, National Central University 3. Design Evaluation of an Automated Bed for Early Detection and Prevention 1 of Decubitus Ulcers in Non-ambulatory Patients1 19. Design of an Ureteropyeloscope Sharmila Nageswaran, School of Bio Sciences & Technology, VIT University; Mkhokheli Ncube, Sudesh Sivarasu, and John Lazarus, MRC/MIRU, Division Rekha Vijayakumar and Sudesh Sivarasu, MRC/MIRU-Division of Biomedical of Biomedical Engineering, Department of Human Biology, Faculty of Health Engineering, Department of Human Biology, Faculty of Health Sciences, Services, University of Cape Town University of Cape Town 20. EEG Electrode Configuration and Source Imaging1 4. Classification of Joints used in Steerable Instruments for Minimally Invasive Abbas Sohrabpour and Yunfeng Lu, Department of Biomedical Engineering, Surgery: A Review2 University of Minnesota; Pongkiat Kankirawatana, Division of Pediatric Filip Jelinek, Ewout Arkenbout, Paul Henselmans, Rob Pessers, and Paul , University of Alabama at Birmingham; Bin He, Department of Breedveld, Biomechanical Engineering Department Faculty Mechanical, Biomedical Engineering, Institute of Engineering in Medicine, University of Maritime & Materials Engineering, Delft University of Technology Minnesota 21. Validation of Peripheral Pulse Wave Analysis Technique to Detect Aortic 5. Assessment of Dental Implantation Osseointegration through Electro- 1 magnetic Actuation and Detection2 Valve State in Continuous-flow LVADs Tai Shin Chia, Graduate Institute of Biomedical Engineering, National Central Ashish Singal, Departments of Biomedical Engineering & Surgery, Medical University; Chin-Sung Chen, Department of Dentistry, Sijhih Cathy General Devices Center, Cardiovascular Division, University of Minnesota; Aimee Hospital; Min-Chun Pan, Graduate Institute of Biomedical Engineering, National Hamel, Matt Larson, and Harrison Kelner, Cardiovascular Division, University of Central University, Department of Dentistry, Sijhih Cathy General Hospital Minnesota; Evan Johnson, Department of Biomedical Engineering, University of Minnesota; Peter Eckman, Cardiovascular Division, University of Minnesota 6. Design of a Stiff Steerable Grasper for Sinus Surgery2 22. Electromagnetic Fields Impede Growth and Adherence of Staphylococcus Andria Remirez, Ray Lathrop, Paul Russell, III, and Robert Webster, III, 2 Department of Mechanical Engineering, Vanderbilt University Aureus on Endotracheal Tubing Ashish Singal and Nicole Pardo, Medical Devices Center, University of 7. Unique Laparoscopic Access Port for Improving Gas Delivery, Quality and Minnesota; Sing Sing Way, & Microbiology, Center for Infectious Surgical Outcomes2 Diseases & Microbiology Research, University of Minnesota Douglas Ott, Chief Medical Officer, Lexoin Medical, Adjunct Professor, Department of Biomedical Engineering, Mercer University 23. Electro-hydraulic Robotic Manipulator with Multiple Instruments for Minimally Invasive Surgery2 8. NOTES Closure of Esophageal Punctures and Fistulas using Suction Abolfazl Pourghodrat, Department of Mechanical & Materials Engineering, Countertraction and Nitinol Clips2 University of Nebraska-Lincoln; Carl Nelson, Department of Mechanical & Robert Brooks, Thomas Looi, and James Drake, Center for Image Guided Materials Engineering, University of Nebraska-Lincoln, UNMC Center for Innovation & Therapeutic Intervention, Hospital for Sick Children Advanced Surgical Technology, University of Nebraska Medical Center; Dmitry 9. Neuromodulation on Bladder Capacity in Conscious Sheep1 Oleynikov, UNMC Center for Advanced Surgical Technology, University of Xin Su and Thaddeus Brink, Global Neuromodulation Research, Medtronic, Inc.; Nebraska Medical Center Angela Nickles, Physiology Research Laboratory, Medtronic, Inc.; Dwight Nelson, 24. Miniature Fluidic Actuators for Surgical Robotics2 Global Neuromodulation Research, Medtronic, Inc. Abolfazl Pourghodrat and Carl Nelson, Department of Mechanical & Materials 10. A Socially Assistive Robot that can Monitor affect of the Elderly during Engineering, University of Nebraska-Lincoln Meal-time Assistance2 25. Flow Simulation of Cardiac Defects to Evaluate Effectiveness of Occlusion Derek McColl, Department of Mechanical & Industrial Engineering, University of Devices1 Toronto; Goldie Nejat, Toronto Rehabilitation Institute Vaibhavi Sonetha, Centre for Research in Nanotechnology & Sciences, Indian 11. Procedure-specific Guidewires to Facilitate Safer Structural Heart Institute of Technology Bombay, Department of Biomedical Engineering, Intervention2 D.J. Sanghvi College of Engineering; Jayesh Bellare, Centre for Research in Erik Sorensen, Lake Region Medical Nanotechnology & Sciences, Department of Chemical Engineering, Indian Institute of Technology Bombay 12. Towards Crowd-based Needfinding in Medical Device Development2 2 Cory Schaffhausen and Timothy Kowalewski, Department of Mechanical 26. Automated Fluorescence Microscope for Tuberculosis Detection Engineering, University of Minnesota Kylie de Jager, Shaun Fickling, and Sriram Krishnan, MRC/UCT Medical Imaging Research Unit, University of Cape Town; Massi Jabbari, Hochschule Mannheim; 1 13. High-speed Visualization of a Steam Pops during Radiofrequency Ablation Genevieve Warner Learmouth, Division of Anatomical Pathologu, University of Stephen Quallich, Ryan Goff, and Paul Iaizzo, Departments of Biomedical Cape Town; Tania Douglas, MRC/UCT Medical Imaging Research Unit, University Engineering & Surgery, University of Minnesota of Cape Town 2 14. Sensorized Cannula for Measuring Body Wall Forces During Surgery 27. Design of MRI-compatible Hemiparesis Rehabilitation Device1 Paul Loschak, Intuitive Surgical Operations, Inc., Harvard School of Engineering Lauren Lacey, Arnold Maliki, Debapriya Bhattacharjee, James Veldhorst, and Jun & Applied Sciences; Smita De, Intuitive Surgical Operations, Inc., Department of Ueda, School of Mechanical Engineering, Georgia Institute of Technology , Stanford Medical School; Amy Kerdok, Intuitive Surgical Operations, Inc. 28. A System for Optimizing Medical Device Development using Finite 15. Preliminary Comparison of Laparoendoscopic Single-site Surgery Element Analysis Predictions1 Instrumentation with Novice Surgical Interns: How Usability Testing Can 1 Chi-Lun Lin, Department of Mechanical Engineering, University of Minnesota; Reveal Human Factors Issues Prior to Errors in the OR Ashutosh Srivastava, ANSYS, Inc.; Dane Coffey and Daniel Keefe, Department Bethany Lowndes, Bernadette McCrory, Chad LaGrange, David Farley, and of Computer Science & Engineering, University of Minnesota; Marc Horner M. Susan Hallbeck, Mayo Clinic, University of Nebraska-Lincoln, University of and Mark Swanson, ANSYS, Inc.; Arthur Erdman, Department of Mechanical Nebraska Medical Center Engineering, University of Minnesota 1 16. A Supine Gait Training Device for Stroke Rehabilitation 29. Influence of Stretch Ratio on the Measurement of Arterial Stiffness Using Fang Ming Lim, Ruyi Foong, and Haoyong Yu, Engineering Design & Innovation Indentation1 Centre, National University of Singapore Shijia Zhoa, Department of Mechanical & Materials Engineering, University of 17. A Portable Powered Knee-Ankle-Foot Orthosis1 Nebraska-Lincoln; Mitchelle Fullerton, Department of Bioengineering, Clemson Gong Chen and Haoyong Yu, Department of Biomedical Engineering, National University; Carl Nelson and Linxia Gu, Department of Mechanical & Materials University of Singapore Engineering, University of Nebraska-Lincoln

Final two-page technical briefs will be published in the June or September 2014 Issues of the ASME Journal of Medical Devices 12 The target date of publication in the ASME Journal of Medical Devices for each paper is denoted by a 1 for the June Issue and by a 2 for the September Issue. Scientific Poster Session Wednesday, April 9, 5:30 p.m. - 7:00 p.m. DQ Room, TCF Bank Stadium

30. Peritoneal Microbubble Oxygenation (PMO): An Extrapulmonary 43. Customized Insole Fabrication for Foot Deformities in Leprosy Patients1 Respiration Treatment in Rabbits2 Sathish Kumar Paul, The Leprosy Mission, School of Bio Sciences & Technology, Nathan Legband, Department of Mechanical & Material Engineering, University VIT University; Rekha Vijayakumar, School of Bio Sciences & Technology, VIT of Nebraska-Lincoln; Jameel Feshitan and Mark Borden, Department of University; Sudesh Sivarasu, MRC/MIRU – Division of Biomedical Engineering, Mechanical Engineering, University of Colorado-Boulder; Benjamin Terry, Department of Human Biology, Faculty of Health Sciences, University of Cape Department of Mechanical & Material Engineering, University of Nebraska- Town Lincoln 44. Measurement of Biomechanical Properties of Tissues under Uniaxial Stress1 31. Performance Testing of Fast Read Digital Thermometers2 Ashish Singal, Departments of Surgery & Biomedical Engineering, University of Oleg Vesnovsky, Center for Devices & Radiological Health, US Food & Drug Minnesota; Charles Soule, Department of Surgery, University of Minnesota; Paul Administration; L.D. Timmie Topoleski, Center for Devices & Radiological Health, Iaizzo, Departments of Surgery & Biomedical Engineering, Integrative Biology & US Food & Drug Administration, Department of Mechanical Engineering, Physiology, Institute for Engineering in Medicine, University of Minnesota University of Maryland; Lawrence Grossman and Jon Casamento, Center for 45. Physiological Tissue Response to Various Ablative Modalities1 Devices & Radiological Health, US Food & Drug Administration; Liang Zhu, Ashish Singal, Departments of Surgery, Biomedical Engineering, University of Department of Mechanical Engineering, University of Maryland Minnesota; Charles Soule, Department of Surgery, University of Minnesota; John 32. A Novel Articulated Drive Mechanism for Multifunctional NOTES Robot2 Ballard, Department of Electrical & Computer Engineering, Medical Devices Tao Shen, Department of Mechanical & Materials Engineering, University of Center, University of Minnesota; Erik Cressman, Interventional , Nebraska-Lincoln; Kevin Warburton, Department of Mechanical & Biomedical University of Minnesota; Paul Iaizzo, Departments of Surgery & Biomedical Engineering, Boise State University; Abolfazl Pourghodrat, Department of Engineering, Integrative Biology & Physiology, Institute for Engineering in Mechanical & Materials Engineering, University of Nebraska-Lincoln; Carl Medicine, University of Minnesota Nelson, Department of Mechanical & Materials Engineering, University of 46. Enhancement of Long Bone Fracture Healing by Local Soft Tissue Nebraska-Lincoln, Department of Surgery, University of Nebraska Medical Compression1 Center; Dmitry Oleynikov, Department of Surgery, University of Nebraska Ernest Chisena, St. Catherine of Siena Medical Center & VA Medical Center; Medical Center Jahangir Rastegar, Mechanical Engineering Department, Stony Brook University; 33. A Cable-driven Grasper with Decoupled Motion and Forces2 Robert Chisena, Department of Mechanical & Nuclear Engineering, Penn State Baoliang Zhao and Carl Nelson, Department of Mechanical & Materials University Engineering, University of Nebraska-Lincoln 47. New Pedicle Screw Design with Expandable Shell for Low Bone Quality1 34. Air Retention Device for Colonoscopy Procedures2 Teyfik Demir and Mehmet Örmeci, Department of Mechanical Engineering, Michael McEniry, Carl Nelson, Ross Oborny, and Lauren Glett, Department of TOBB University of Economics & Technology Mechanical & Materials Engineering, University of Nebraska-Lincoln; Joy Wolfe, 48. Self-assisted Wide-angle Nasopharyngeal Carcinoma (SWAN) Surveillance Jefferson Community Health Center Delivery System1 35. Mobility-enhancing Fall-prevention Device for Physical Rehabilitation1 Hongliang Ren, Department of Biomedical Engineering, National University Carl Nelson, Department of Mechanical & Materials Engineering, University Hospital, National University of Singapore; Lim Chwee Ming, Department of of Nebraska-Lincoln; Judith Burnfield, Institute for Rehabilitation Science & Otolaryngology, National University Hospital, National University of Singapore; Engineering, Madonna Rehabilitation Hospital; Linxia Gu, Department of Neerajha Ram, Khor Jing An, Ong Jun Shu, Ng Kwok Yang Paul, and Anselina Goh Mechanical & Materials Engineering, University of Nebraska-Lincoln Sok Mian, Department of Biomedical Engineering, National University Hospital, National University of Singapore 36. Forearm Attachment for Post-amputation Weight Lifting Exercise1 49. Nasoveillance: Delivering In-vivo Surveillance of Nasopharyngeal Carl Nelson, Department of Mechanical & Materials Engineering, University 1 of Nebraska-Lincoln; Judith Burnfield, Institute for Rehabilitation Science & Carcinoma Engineering, Madonna Rehabilitation Hospital; Linxia Gu, Henry Ems, and Hongliang Ren, Department of Biomedical Engineering, National University Quentin Ens, Department of Mechanical & Materials Engineering, University of Hospital, National University of Singapore; Lim Chwee Ming, Department of Nebraska-Lincoln Otolaryngology, National University Hospital, National University of Singapore; Si Wei Goh, Rina Hee, Jhen Jin Saw, and JaeJung Kim, Department of Biomedical 37. Casper: An Assistive Kitchen Robot to Promote Aging in Place2 Engineering, National University Hospital, National University of Singapore Paul Bovbel, Department of Mechanical & Industrial Engineering, University 50. Monolithic Fabrication of Millimeter-scale Surgical Devices with Integrated of Toronto; Goldie Nejat, Department of Mechanical & Industrial Engineering, 2 University of Toronto, Toronto Rehabilitation Institute Sensing Joshua Gafford, Samuel Kesner, Robert Wood, and Conor Walsh, Harvard School 38. Design of a Naturalistic Navigational Virtual Reality using Oculus Rift2 of Engineering & Applied Sciences, Wyss Institute for Biologically Inspired Ahmad Byagowi, Saloni Singhal, Michael Lambeta, Cassandra Aldaba, and Zahra Engineering Moussavi, Departments of Electrical & Computer Engineering, University of 1 Manitoba 51. Cervical Spine Immobilization Device for Emergency Response Alperen Degirmenci, Benjamin Goldberg, Lukas Bielskis, and Shanna Wiggins, 39. Comparison of Irreversible Electroporation, Cryo, and Thermal Ablations School of Engineering & Applied Sciences; Panagiotis Polygerinos, School on Cardiovascular Cells of Engineering & Applied Sciences, Wyss Institute for Biologically Inspired Chunlan Jiang and Jeunghwan Choi, Department of Mechanical Engineering, Engineering, Harvard University; Donal Holland, School of Engineering & Applied University of Minnesota; Dushyant Mehra, Department of Biomedical Sciences, Trinity College; Sophia Dyer, Boston EMS, Boston Medical Center; Engineering, University of Minnesota; Pong Patana-anake, Department of Conor Walsh, School of Engineering & Applied Sciences, Trinity College Mechanical Engineering, University of Minnesota; John Bischof, Departments of 1 Mechanical & Biomedical Engineering, University of Minnesota 52. Cardiovascular Impacts of High Frequency Chest Compression George O’Clock, Jongwon Lee, and Yong Wan Lee, Department of Pediatrics, 40. Neural Cells Show Higher Sensitivity to Irreversible Electroporation University of Minnesota Compared to Cancer and Cardiovascular Cells 1 Chunlan Jiang and Pong Patana-anake, Department of Mechanical Engineering, 53. Numerical Characterization of Bone Defects after Dental Implantation University of Minnesota; John Bischof, Departments of Mechanical & Bin-Xun Hsieh, Graduate Institute of Biomedical Engineering, National Central Biomedical Engineering, University of Minnesota University; Chin-Sung Chen, Department of Dentistry, Sijhih Cathy General Hospital; Min-Chun Pan, Graduate Institute of Biomedical Engineering, National 41. In-vivo Surveillance of Nasopharyngeal Carcinoma2 Central University, Department of Mechanical Engineering, National Central Hongliang Ren, Department of Biomedical Engineering, National University University Hospital, National University Singapore; Lim Chwee Ming, Department of 54. An Intraventricular Soft Robotic Pulsatile Assist Device for Right Ventricular Biomedical Engineering, National University Hospital, National University 1 Singapore; Justin Tan Swee Yang, Wang Jun Xiang, Lin Mu, Vanessa Mak Wei- Heart Failure Lin, and Dhashni Manogaran, Department of Biomedical Engineering, National Evelyn Park, Nikhil Mehandru, Tonatiuh Lievano Beltran, and Erik Kraus, Harvard School of Engineering & Applied Sciences; Donal Holland, Harvard School of University Hospital, National University Singapore Engineering & Applied Sciences, Wyss Institute for Biologically Inspired 42. Novel Stress Radiography Device for Measuring Knee Laxity at Various Engineering, Trinity College; Panagiotis Polygerinos, Harvard School of Flexion Angles – Laxmeter1 Engineering & Applied Sciences, Wyss Institute for Biologically Inspired Sudesh Sivarasu, MRC/MIRU, Biomedical Engineering Division, Department of Engineering; Nikolay Vasilyev, Boston Children’s Hospital; Conor Walsh, Harvard Human Biology, Faculty of Health Sciences, University of Cape Town; Sarthak School of Engineering & Applied Sciences, Wyss Institute for Biologically Inspired Patnaik, OrthoOne Hospital Engineering

Final two-page technical briefs will be published in the June or September 2014 Issues of the ASME Journal of Medical Devices The target date of publication in the ASME Journal of Medical Devices for each paper is denoted by a 1 for the June Issue and by a 2 for the September Issue. 13 Scientific Poster Session Wednesday, April 9, 5:30 p.m. - 7:00 p.m. DQ Room, TCF Bank Stadium 55. Development of an Adjustable Sinus Tarsi Device for Flatfoot Correction: A 71. Critical and Complex Technological Capability Development for Health Pilot Study in a Sawbones Model1 Care Delivery: Multi-year Field Study of a Surgical (da Vinci) Robot in a Multi- Robert Rizza, Department of Mechanical Engineering, Milwaukee School of specialty Hospital2 Engineering; XueCheng Liu, Scott Van Valin, and Roger Lyon, Department of Ujjal Kumar Kukherjee, Carlson School of Management, University of , Medical College of Wisconsin Minnesota; Shoubhik Sinha, College of Science & Engineering, University of 56. Miniaturized Radio Frequency Telemetric Pacemaker with Anti-arrhythmic Minnesota; Scott Bosch, Biomedical Engineering Group, Park Nicollet Health Pacing Protocol1 Services; Kingshuk Sinha, Carlson School of Management, University of Kanchan Kulkarni, Sze Yuen Tan, and Elena Tolkacheva, Department of Minnesota Biomedical Engineering, University of Minnesota 72. Tool Tracking in a Laparoscopic Virtual Reality Training System1 57. Device for Quantifying Neural Response and Other Conditions by Mohsen Zahiri, Department of Mechanical & Materials Engineering, University Measuring Sweat Gland Function2 of Nebraska-Lincoln; Ryan Booton, College of , University of Jun Young Lim, Electrical & Computer Engineering; Ming-Lun Wu, Biomedical Nebraska Medical Center; Carl Nelson, Department of Mechanical & Materials Engineering, University of Florida; William Kennedy, Neurology, University of Engineering, University of Nebraska-Lincoln; Ka-Chun Siu, School of Allied Minnesota; Stephen Campbell, Electrical & Computer Engineering Health Professions, University of Nebraska Medical Center 2 58. P300 and Motor Imagery Based BCI for Controlling Wheelchairs2 73. A New Surgical Barbed Staple for Minimally Invasive Surgery Hung-Chyun Chou, Narendra Prataksita, Yi-Tseng Lin, and Chung-Hsien Kuo, Farhad Javid, Damiano Pasini, and Jorge Angeles, Department of Mechanical Department of Electrical Engineering, National Taiwan University of Science & Engineering, McGill University Technology 74. Online Free Anatomy Registration via Non-contact Skeletal Tracking for 2 59. Paradigm Shift Allows for Readily Available Therapeutic Hypothermia Collaborative Human/Robot Interaction in Surgical Robotics Treatment of the Head Region1 John O’Neill and Timothy Kowalewski, Department of Mechanical Engineering, Michael Zumbrunnen, InControl Biomedical LLC University of Minnesota 75. Development of a Metallic Biodegradable Stent Based on Galvanic 60. Design and Characterization of an Endovascular Mechanical 1 Thrombectomy Device1 Corrosion Jason Szafron, Andrea Muschenborn, and Duncan Maitland; Department of Rajib Barua, Department of Mechanical Engineering, McGill University; Huseyin Biomedical Engineering, Texas A&M University Aydin, Sriraman Rajagopalan, and Stephen Yue, Department of Materials & Metallurgical, McGill University; David Frost, Department of Mechanical 61. Tissue Bond Strength as a Function of Applied Fusion Pressure2 Engineering, McGill University; Olivier Bertrand, Quebec Heart & Lung Institute, Nicholas Anderson, Eric Kramer, James Cezo, Virginia Ferguson, and Mark Laval University; Rosaire Mongrain, Department of Mechanical Engineering, Rentschler, Department of Mechanical Engineering, University of Colorado at McGill University Boulder 76. Development of a Distal Tip Extension Mechanism for Endoscopes2 62. A Computational Framework to Evaluate the Effectiveness of Intrasaccular Ibrahim Kadhim and Rajesh Shanbhag, Department of Mechanical Engineering, Therapies for Cerebral Aneurysms1 Ohio University; JungHun Choi, Department of Mechanical Engineering & Ashok Nageswaran, Covidien Neurovascular; Rahul Ramachandran and Biomedical Engineering Program, Ohio University Ananthkrishnan Gopalakrishnan, Stryker Corporation; Todd Abruzzo, College 77. Pacemaker and Defibrillator Lead Tip Interactions in Porcine Cardiac Tissue of Medicine, University of Cincinnati; Balakrishna Haridas, Department of 1 Biomedical Engineering, University of Cincinnati and Tissue Substitute on the Bench Donna Walsh, Nandini Duraiswamy, and Oleg Vesnovsky, Center for Devices & 63. Design of Stent Crimper using Braided Wire Structure2 Radiological Health, US Food & Drug Administration; L.D. Timmie Topoleski, Mitchell Kuss, Shijia Zhao, and Linxia Gu, Department of Mechanical & Department of Mechanical Engineering, University of Maryland Materials Engineering, University of Nebraska-Lincoln 78. Preliminary Development of a Robust Multi-link Modular Robotic System 64. A Wearable Posture Detection Device for Inpatient Healthcare2 for Improvement of Colonoscopy Intubation Process2 Nhat Nguyen Vo, Department of Computer & Electrical Engineering, National Kaiqiang Liu and Cory Sheerer, Department of Mechanical Engineering, Ohio University of Singapore; Haoyong Yu, Department of Biomedical Engineering, University; Junghun Choi, Department of Mechanical & Biomedical Engineering, National University of Singapore Ohio University 65. Inter-landmark Measurements from Lodox Statscan Images2 79. Medical Equipment to make Colonoscopy Procedures Safer for Physicians: Chipo Chimhundu, Biomedical Engineering Programma, MRC/UCT Medical Control Head Holder and Splatter Shield2 Imaging Research Unit, University of Cape Town; Julian Smit, Division of Rajesh Shanbhag and Ibrahim Kadhim, Department of Mechanical Engineering, Geomatics, University of Cape Town; Sudesh Sivarasu and Tania Douglas, Ohio University; David Drozek, Department of Specialty Medicine, Ohio Biomedical Engineering Programma, MRC/UCT Medical Imaging Research Unit, University; Junghun Choi, Department of Mechanical Engineering, Biomedical University of Cape Town Engineering Program, Ohio University 66. Design and Characterization of a Resistively Heated Shape Memory 80. Detection of Looping during Colonoscopy by using Embedded Bending Polymer Micro-release Device1 Sensors2 Landon Nash, Mark Wierzbicki, and Duncan Maitland, Department of Mike Bruce, Department of Mechanical Engineering, Ohio University; David Biomedical Engineering, Texas A&M University Drozek, Department of Specialty Medicine, Ohio University; JungHun Choi, 67. A Framework for Calibrating and Benchmarking Computer Vision Department of Mechanical Engineering, Biomedical Engineering Program, Ohio Algorithms in Surgical Robotics2 University Rodney Dockter and Timothy Kowalewski, Department of Mechanical 81. Design of Dividable Colonoscope Sheath2 Engineering, University of Minnesota Al-Jebur Hussein, Department of Mechanical Engineering, Ohio University; 68. Shape Deposition Manufacturing of a Soft, Atraumatic, Deployable JungHun Choi, Department of Mechanical Engineering, Biomedical Engineering Surgical Grasper2 Program, Ohio University Joshua Gafford, Ye Ding, Andrew Harris, Terrence McKenna, and Panagiotis 82. Disposable Fluidic Self-propelling Robot for Colonoscopy2 Polygerinos, Harvard School of Engineering & Applied Sciences; Donal Holland, Abolfazl Pourghodrat and Hossein Dehghani, Department of Mechanical & Trinity College; Arthur Moser, Beth Israel Deaconess Medical Center; Conor Materials Engineering, University of Nebraska-Lincoln; Carl Nelson, Department Walsh, Harvard School of Engineering & Applied Sciences, Wyss Institute for of Mechanical & Materials Engineering, University of Nebraska-Lincoln, UNMC Biologically Inspired Engineering Center for Advanced Surgical Technology, University of Nebraska Medical 69. Medical Simulators for Developing Countries via Low-cost 2D Position Center; Dmitry Oleynikov, UNMC Center for Advanced Surgical Technology, Tracking2 University of Nebraska Medical Center; Prithviraj Dasgupta, Computer Science Robin Walz, Zachary Meier, Michale Winek, and Timothy Kowalewski, Department, University of Nebraska-Omaha; Benjamin Terry, Department of Department of Mechanical Engineering, University of Minnesota Mechanical & Materials Engineering, University of Nebraska-Lincoln, UNMC 2 Center for Advanced Surgical Technology, University of Nebraska Medical 70. Low-cost, Small-footprint, Barometer-Based CPR Feedback Device Center Qian Wan, School of Engineering & Applied Sciences, Harvard University; Daniel Vogt, School of Engineering & Applied Sciences, Wyss Institute for Biologically 83. Biomimetic Attachment to the Gastrointestinal Tract2 Inspired Engineering; Zivthan Dubrovsky, Wyss Institute for Biologically Inspired Wanchuan Xie and Benjamin Terry, Department of Mechanical & Materials Engineering Engineering, University of Nebraska-Lincoln

Final two-page technical briefs will be published in the June or September 2014 Issues of the ASME Journal of Medical Devices 14 The target date of publication in the ASME Journal of Medical Devices for each paper is denoted by a 1 for the June Issue and by a 2 for the September Issue. Scientific Poster Session Wednesday, April 9, 5:30 p.m. - 7:00 p.m. DQ Room, TCF Bank Stadium

84. Simulation Method for Predicting Tissue Electrical Properties during 99. Multi-joint Rigidity-testing Device for Titrating Medication and Deep Colonoscopy1 Brain Stimulation Therapies1 Chen Tang, Randolph Robert, and JungHun Choi, Department of Mechanical Kevin Mohsenian, Allison Connolly, and Matthew Johnson, Department of Engineering, Ohio University Biomedical Engineering, University of Minnesota 85. Component Validation of High Power Transcutaneous Energy Transfer 100. Printing Strain Gauges on Surgical Instruments for Force Measurement2 System1 Frank Hammond, III, Michael Smith, and Robert Wood, School of Engineering Joseph Tartakoff, Department of Mechanical Engineering, Rochester Institute & Applied Sciences, Harvard University of Technology; Coley Duncan, Infectious Disease Unit, Rochester General 1 Hospital; Steven Day, Department of Mechanical Engineering, Rochester 101. Computational Modeling of Restenosis Formation after Stenting Shijia Zhoa and Linxia Gu, Department of Mechanical & Materials Institute of Technology Engineering, University of Nebraska-Lincoln 1 86. Heart Signal Abnormality Detection using Artificial Neural Networks 102. Feasibility of a Low Cost Instrumented Trocar for Universal Surgical Ali Haider and Reza Fazel-Rezai, Department of Electrical Engineering, Procedure Analyses2 University of North Dakota Jalal Rana and Timothy Kowalewski, Department of Mechanical Engineering, 87. Design of a Swallowable Micro-robotic Capsule for Measuring Small University of Minnesota 2 Intestine Pressure 103. Implantation and Carrier Mechanism for Long-term Biosensing in the Pengbo Li and Benjamin Terry, Department of Mechanical & Materials Small Intestine2 Engineering, University of Nebraska-Lincoln Alfred Tsubaki, Wetson Lewis, and Benjamin Terry, Department of Mechanical 88. Automatic Instrument Tracking Endo-illuminator for Intraocular & Materials Engineering, University of Nebraska-Lincoln 2 Surgeries 104. Augmented Reality for Improving Catheterization in MRI-guided Ke Cao and Ramiro Pinon, Department of Mechanical Engineering, Cardiac Electrophysiology Therapy1 University of Michigan; Ira Schachar and Thiran Jayasundera, Department of Yue Chen, Ka-Wai Kwok, and Jia Ge, Department of Engineering, University of , Kellogg Eye Center, University of Michigan; Shorya Awtar, Georgia; Yang Hu, Department of Surgery & Cancer, Imperial College; Mable Department of Mechanical Engineering, University of Michigan Fok, Department of Engineering, University of Georgia; Kent Ronald Nilsson, 89. Safe Wireless Power Design for Implanted Medical Devices1 Athens Regional Medical Center, University of Georgia & Georgia Regents Vlad Bluvshtein and Lori Lucke, Minnetronix, Inc. University Medical Partnership; Zion Tsz Ho Tse, Department of Engineering, University of Georgia 90. Dynamic Calibration Methods for Instrumented Laparoscopic Surgical Graspers2 105. Engineers in Scrubs - A New Graduate Training Program for Biomedical Michael Winek, Robert Sweet, and Timothy Kowalewski, Department of Engineers at the University of British Columbia2 Mechanical Engineering, University of Minnesota Antony Hodgson, Roger Tam, and HF Machiel Van der Loos, Graduate Program in Biomedical Engineering, University of British Columbia 91. Cost Effective Reliability Analysis and Testing of Medical Devices2 Lori Lucke and John Whitehurst, Minnetronix, Inc. 106. Design and Implementation of Assistive Devices for Post-stroke Rehabilitation of Hand and Fingers1 92. Epidural Pressure Measurements from Various BMI Obstetric Patients2 Kevin Kao, Department of Mechanical Engineering, National Central Neil Vaughan and Venketesh Dubey, Faculty of Science & Technology, University; Jheng-Jie Huang, Graduate Institute of Biomedical Engineering, Bournemouth University; Michael Wee and Richard Isaacs, Poole Hospital National Central University; Min-Chun Pan, Department of Mechanical NHS Foundation Trust Engineering, Graduate Institute of Biomedical Engineering, National Central 93. Synthetic Methods for Ultrasound-guided Epidural Insertion University Simulation1 107. Computer Aided Ruler Based on Symmetric Points Detection for Botox Neil Vaughan and Venketesh Dubey, Faculty of Science & Technology, Injections2 Bournemouth University; Michael Wee and Richard Isaacs, Poole Hospital Leila Azinfar, Mohammad Reza Ravanfar, and Reza Fazek-Rezai, Department NHS Foundation Trust of Electrical Engineering, University of North Dakota 94. VR Simulation Based Assessment Objectives for Epidural Training1 108. Multi-tine Deep Brain Stimulation Leads to Shape Neural Activation in Neil Vaughan and Venketesh Dubey, Faculty of Science & Technology, Three Dimensions1 Bournemouth University; Michael Wee and Richard Isaacs, Poole Hospital John LaRoy, Benjamin Teplitzky, and Matthew Johnson, Department of NHS Foundation Trust Biomedical Engineering, University of Minnesota 95. Towards a Novel, Implantable Limb Lengthening Device1 109. Wearable Virtual White Cane: Assistive Technology for Navigating the Daniel Farley, Heidi-Lynn Ploeg, and Michael Zinn, Department of Mechanical Virtually Impaired1 Engineering, University of Wisconsin-Madison Yabiao Gao and Ka-Wai Kwok, College of Engineering, University of Georgia; 96. Real-time Tissue Differentiation using Fiber Optic Sensing in Laser Rahul Chandrawanshi, Indian Institute of Technology; Alex Squires, College of Catheters2 Engineering, University of Georgia; Amy Nau, University of Pittsburgh Medical Darrin Beekman, Sachin Bijadi, and Timothy Kowalewski, Department of Center; Zion Tsz Ho Tse, College of Engineering, University of Georgia Mechanical Engineering, University of Minnesota 110. Academia and Industry in Medical Device Innovation: A Case Report2 97. Determining Magnetic Nanoparticle Distribution within Biological Laura Paulsen, Medical Devices Center, University of Minnesota; Raed Rizq, Boston Scientific Corporation; Arthur Erdman, Medical Devices Center, Systems using CT Imaging University of Minnesota; Jim Chiapetta, Boston Scientific Corporation Leoni Rott, Institute for Multiphase Processes, Leibniz University of Hannover, Department of Mechanical Engineering, University of Minnesota; 111. In-vivo Monitoring of HIFU Induced Temperature Rise in Porcine Liver Michael Etheridge, Department of Mechanical Engineering, University of using Magnetic Resonance Thermometry2 Minnesota; Almer Meinken and Birgit Glasmacher, Institute for Multiphase Seyed Ahmad Reza Dibaji, Department of Mechanical & Materials Processes, Leibniz University of Hannover; John Bischof, Department of Engineering, College of Engineering & Applied Science, University of Mechanical & Biomedical Engineering, University of Minnesota Cincinnati; Janaka Wansapura, Imaging Research Center, Cincinnati Children’s 1 Hospital Medical Center; Matthew Myers, Division of Solid & Fluid Mechanics, 98. Biologically Inspired Soft Robot for Thumb Rehabilitation Center for Devices & Radiological Health, US Food & Drug Administration; Paxton Maeder-York, Tyler Clites, Emily Boggs, and Ryan Neff, Harvard Rupak Banerjee, Department of Mechanical & Materials Engineering, College School of Engineering & Applied Sciences; Panagiotis Polygerinos and Donal of Engineering & Applied Science, University of Cincinnati Holland, Harvard School of Engineering & Applied Sciences, Wyss Institute of Biologically Inspired Engineering, Harvard University; Leia Stirling and 112. Innovative Sutureless Microvascular Anastomotic Device with Kevin Galloway, Wyss Institute of Biologically Inspired Engineering, Harvard Embedded Doppler Flow Monitoring1 University; Catherine Wee, Spaulding Hospital for Continuing Medical Care; Daniel Morradian, Honeywell-Renier Chair in Innovation Management, The Conor Walsh, Harvard School of Engineering & Applied Sciences, Wyss Technology Leadership Institute, University of Minnesota; Tracy Konobeck Institute of Biologically Inspired Engineering, Harvard University and Willaim Kuester, Baxter International; Mike Bravo, NAMSA

Final two-page technical briefs will be published in the June or September 2014 Issues of the ASME Journal of Medical Devices The target date of publication in the ASME Journal of Medical Devices for each paper is denoted by a 1 for the June Issue and by a 2 for the September Issue. 15 2014 Technical Organizing Committee Taner Akkin Neuroengineering 1: Neuroimaging Medical Device Fellows Programs Ben Arcand Medical Device Innovation Dawn Bardot “Regulatory Science” Symposium Joan Bechtold Computational Spine Biomechanics John Bischof Global Health Jeff Bischoff Computational Spine Biomechanics Jesús Cabrera Three-in-Five Competition Tianhong Cui Medical Micro & Nano Systems Lucy Dunne Wearable Medical Devices Leon Durivage Implementing Secure Wireless Communication in Medical Devices Emad Ebbini Image-guided Interventions Peter Edelman Biomaterials Michael Eggen Cardiovascular 3: Cardiac Lead Extraction Michael Finch Emerging Medical Innovation Valuation Competition Devices for Developing Nations: Examples of Low Cost High Impact Projects from Gwenyth Fischer Pediatric & Adult Medicine Andrew Hansen Prosthetics & Orthotics Kathleen Harder Human Factors 1 Just Herder Three-in-Five Competition Elizabeth Hsiao-Wecksler Fluid Power Medical Devices Cardiovascular 1: Cardiac Keynote Presentations Paul Iaizzo Cardiovascular 4: Pre-Clinical Trials for Cardiac Devices Neuroengineering 3: Peripheral Nerve Stimulation Matthew Johnson Advances in Medical Devices 1 Advances in Medical Devices 2 Surgical Robotics & Computational Surgery Tim Kowalewski Surgical Simulation Hugh Lim Neuroengineering 4: Novel Approaches for Exciting or Inhibiting the Brain Galyna Loughran Computational Spine Biomechanics Rick McVenes Cardiovascular 3: Cardiac Lead Extraction Daniel Mooradian Cardiovascular 6: Advances in Cardiovascular Technology Tina Morrison “Regulatory Science” Symposium Randy Nelson Emerging Medical Innovation Valuation Competition Tay Netoff Neuroengineering 2: Neuron Modulation for Epilepsy Lars Oddsson Wearable Medical Devices Keshab Parhi Implementing Secure Wireless Communication in Medical Devices Medical Device Fellows Programs Saurav Paul Medical Device Innovation Big Data - Bridging Medical Device Design and Healthcare Delivery: Changing Greg Peterson Behaviors Mary Beth Privitera Collaborative Design of Medical Devices Rajesh Rajamani Advances in Sensing Systems on Medical Devices Wei Shen Biomaterials Ronald Siegel Drug Delivery Devices James St. Louis Cardiovascular 5: Pediatric Cardiac Innovation: The Next Generation Rick Stein Human Factors 2: Usability of 3D Printed Medical Devices Hao Su Catheter Robotics Robert Sweet Surgical Simulation Bob Tranquillo Cardiovascular 2: Engineered Tissues for Cardiac Devices Erik van Kuijk Ophthalmic Medical Devices Jean Wyman Technology Needs for Geriatric Care

2014 DMD Conference Planning Committee: John Bischof, Conference Co-Chair Cortney Davis, Assistant Coordinator Maura Donovan, Conference Co-Chair William Durfee, Conference Co-Chair Arthur Erdman, Conference Chair Just Herder, Contributed Papers Co-Chair Jenny Holden, Conference Administrator Paul Iaizzo, Conference Co-Chair Matthew Johnson, Contributed Papers Chair Trisha Johnson, Conference Coordinator Saurav Paul, Conference Co-Chair Gary Williams, AV Technical Specialist

International Advisory Board: Just Herder, Delft University of Technology, The Netherlands

Special Thanks to: ASME Bioengineering Division and World Congress of Biomechanics BioBusiness Alliance of Minnesota Coffman Memorial Union Conference Volunteers Curbside Productions D’Amico Catering Hubbell/Tyner James McCabe Photography and Printing Journal of Medical Devices, American Society of Mechanical Engineers (ASME) LifeScience Alley McNamara Almuni Center PSAV Presentation Services TCF Bank Stadium The Commons Hotel Wallace | Carlson Printing Save the Dates! Design of Medical Devices Conference 2015 April 13, 14-16 The Commons Hotel & McNamara Alumni Center Minneapolis, Minnesota Design of Medical Devices Conference 2016 April 11, 12-14 The Commons Hotel & McNamara Alumni Center Minneapolis, Minnesota