Fundamental Concepts in Time and Frequency Metrology Raul F
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Units and Conversions
Units and Conversions This unit of the Metrology Fundamentals series was developed by the Mitutoyo Institute of Metrology, the educational department within Mitutoyo America Corporation. The Mitutoyo Institute of Metrology provides educational courses and free on-demand resources across a wide variety of measurement related topics including basic inspection techniques, principles of dimensional metrology, calibration methods, and GD&T. For more information on the educational opportunities available from Mitutoyo America Corporation, visit us at www.mitutoyo.com/education. This technical bulletin addresses an important aspect of the language of measurement – the units used when reporting or discussing measured values. The dimensioning and tolerancing practices used on engineering drawings and related product specifications use either decimal inch (in) or millimeter (mm) units. Dimensional measurements are therefore usually reported in either of these units, but there are a number of variations and conversions that must be understood. Measurement accuracy, equipment specifications, measured deviations, and errors are typically very small numbers, and therefore a more practical spoken language of units has grown out of manufacturing and precision measurement practice. Metric System In the metric system (SI or International System of Units), the fundamental unit of length is the meter (m). Engineering drawings and measurement systems use the millimeter (mm), which is one thousandths of a meter (1 mm = 0.001 m). In general practice, however, the common spoken unit is the “micron”, which is slang for the micrometer (m), one millionth of a meter (1 m = 0.001 mm = 0.000001 m). In more rare cases, the nanometer (nm) is used, which is one billionth of a meter. -
Consultative Committee for Amount of Substance; Metrology in Chemistry and Biology CCQM Working Group on Isotope Ratios (IRWG) S
Consultative Committee for Amount of Substance; Metrology in Chemistry and Biology CCQM Working Group on Isotope Ratios (IRWG) Strategy for Rolling Programme Development (2021-2030) 1. EXECUTIVE SUMMARY In April 2017, the Consultative Committee for Amount of Substance; Metrology in Chemistry and Biology (CCQM) established a task group to study the metrological state of isotope ratio measurements and to formulate recommendations to the Consultative Committee (CC) regarding potential engagement in this field. In April 2018 the Isotope Ratio Working Group (IRWG) was established by the CCQM based on the recommendation of the task group. The main focus of the IRWG is on the stable isotope ratio measurement science activities needed to improve measurement comparability to advance the science of isotope ratio measurement among National Metrology Institutes (NMIs) and Designated Institutes (DIs) focused on serving stake holder isotope ratio measurement needs. During the current five-year mandate, it is expected that the IRWG will make significant advances in: i. delta scale definition, ii. measurement comparability of relative isotope ratio measurements, iii. comparable measurement capabilities for C and N isotope ratio measurement; and iv. the understanding of calibration modalities used in metal isotope ratio characterization. 2. SCIENTIFIC, ECONOMIC AND SOCIAL CHALLENGES Isotopes have long been recognized as markers for a wide variety of molecular processes. Indeed, applications where isotope ratios are used provide scientific, economic, and social value. Early applications of isotope measurements were recognized with the 1943 Nobel Prize for Chemistry which included the determination of the water content in the human body, determination of solubility of various low-solubility salts, and development of the isotope dilution method which has since become the cornerstone of analytical chemistry. -
Guide for the Use of the International System of Units (SI)
Guide for the Use of the International System of Units (SI) m kg s cd SI mol K A NIST Special Publication 811 2008 Edition Ambler Thompson and Barry N. Taylor NIST Special Publication 811 2008 Edition Guide for the Use of the International System of Units (SI) Ambler Thompson Technology Services and Barry N. Taylor Physics Laboratory National Institute of Standards and Technology Gaithersburg, MD 20899 (Supersedes NIST Special Publication 811, 1995 Edition, April 1995) March 2008 U.S. Department of Commerce Carlos M. Gutierrez, Secretary National Institute of Standards and Technology James M. Turner, Acting Director National Institute of Standards and Technology Special Publication 811, 2008 Edition (Supersedes NIST Special Publication 811, April 1995 Edition) Natl. Inst. Stand. Technol. Spec. Publ. 811, 2008 Ed., 85 pages (March 2008; 2nd printing November 2008) CODEN: NSPUE3 Note on 2nd printing: This 2nd printing dated November 2008 of NIST SP811 corrects a number of minor typographical errors present in the 1st printing dated March 2008. Guide for the Use of the International System of Units (SI) Preface The International System of Units, universally abbreviated SI (from the French Le Système International d’Unités), is the modern metric system of measurement. Long the dominant measurement system used in science, the SI is becoming the dominant measurement system used in international commerce. The Omnibus Trade and Competitiveness Act of August 1988 [Public Law (PL) 100-418] changed the name of the National Bureau of Standards (NBS) to the National Institute of Standards and Technology (NIST) and gave to NIST the added task of helping U.S. -
Role of Metrology in Conformity Assessment
Role of Metrology in Conformity Assessment Andy Henson Director of International Liaison and Communications of the BIPM Metrology, the science of measurement… and its applications “When you can measure what you are speaking about, and express it in numbers, you know something about it; but when you cannot express it in numbers, your knowledge is of a meagre and unsatisfactory kind” William Thompson (Lord Kelvin): Lecture on "Electrical Units of Measurement" (3 May 1883) Conformity assessment Overall umbrella of measures taken by : ‐manufacturers ‐customers ‐regulatory authorities ‐independent third parties To assess that a product/service meets standards or technical regulations 2 Metrology is a part of our lives from birth Best regulation Safe food Technical evidence Safe treatment Safe baby food Manufacturing Safe traveling Globalization weighing of baby Healthcare Innovation Climate change Without metrology, you can’t discover, design, build, test, manufacture, maintain, prove, buy or operate anything safely and reliably. From filling your car with petrol to having an X‐ray at a hospital, your life is surrounded by measurements. In industry, from the thread of a nut and bolt and the precision machined parts on engines down to tiny structures on micro and nano components, all require an accurate measurement that is recognized around the world. Good measurement allows country to remain competitive, trade throughout the world and improve quality of life. www.bipm.org 3 Metrology, the science of measurement As we have seen, measurement science is not purely the preserve of scientists. It is something of vital importance to us all. The intricate but invisible network of services, suppliers and communications upon which we are all dependent rely on metrology for their efficient and reliable operation. -
The Kelvin and Temperature Measurements
Volume 106, Number 1, January–February 2001 Journal of Research of the National Institute of Standards and Technology [J. Res. Natl. Inst. Stand. Technol. 106, 105–149 (2001)] The Kelvin and Temperature Measurements Volume 106 Number 1 January–February 2001 B. W. Mangum, G. T. Furukawa, The International Temperature Scale of are available to the thermometry commu- K. G. Kreider, C. W. Meyer, D. C. 1990 (ITS-90) is defined from 0.65 K nity are described. Part II of the paper Ripple, G. F. Strouse, W. L. Tew, upwards to the highest temperature measur- describes the realization of temperature able by spectral radiation thermometry, above 1234.93 K for which the ITS-90 is M. R. Moldover, B. Carol Johnson, the radiation thermometry being based on defined in terms of the calibration of spec- H. W. Yoon, C. E. Gibson, and the Planck radiation law. When it was troradiometers using reference blackbody R. D. Saunders developed, the ITS-90 represented thermo- sources that are at the temperature of the dynamic temperatures as closely as pos- equilibrium liquid-solid phase transition National Institute of Standards and sible. Part I of this paper describes the real- of pure silver, gold, or copper. The realiza- Technology, ization of contact thermometry up to tion of temperature from absolute spec- 1234.93 K, the temperature range in which tral or total radiometry over the tempera- Gaithersburg, MD 20899-0001 the ITS-90 is defined in terms of calibra- ture range from about 60 K to 3000 K is [email protected] tion of thermometers at 15 fixed points and also described. -
Handbook of MASS MEASUREMENT
Handbook of MASS MEASUREMENT FRANK E. JONES RANDALL M. SCHOONOVER CRC PRESS Boca Raton London New York Washington, D.C. © 2002 by CRC Press LLC Front cover drawing is used with the consent of the Egyptian National Institute for Standards, Gina, Egypt. Back cover art from II Codice Atlantico di Leonardo da Vinci nella Biblioteca Ambrosiana di Milano, Editore Milano Hoepli 1894–1904. With permission from the Museo Nazionale della Scienza e della Tecnologia Leonardo da Vinci Milano. Library of Congress Cataloging-in-Publication Data Jones, Frank E. Handbook of mass measurement / Frank E. Jones, Randall M. Schoonover p. cm. Includes bibliographical references and index. ISBN 0-8493-2531-5 (alk. paper) 1. Mass (Physics)—Measurement. 2. Mensuration. I. Schoonover, Randall M. II. Title. QC106 .J66 2002 531’.14’0287—dc21 2002017486 CIP This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage or retrieval system, without prior permission in writing from the publisher. The consent of CRC Press LLC does not extend to copying for general distribution, for promotion, for creating new works, or for resale. Specific permission must be obtained in writing from CRC Press LLC for such copying. -
Simulating Nucleic Acids from Nanoseconds to Microseconds
UC Irvine UC Irvine Electronic Theses and Dissertations Title Simulating Nucleic Acids from Nanoseconds to Microseconds Permalink https://escholarship.org/uc/item/6cj4n691 Author Bascom, Gavin Dennis Publication Date 2014 Peer reviewed|Thesis/dissertation eScholarship.org Powered by the California Digital Library University of California UNIVERSITY OF CALIFORNIA, IRVINE Simulating Nucleic Acids from Nanoseconds to Microseconds DISSERTATION submitted in partial satisfaction of the requirements for the degree of DOCTOR OF PHILOSOPHY in Chemistry, with a specialization in Theoretical Chemistry by Gavin Dennis Bascom Dissertation Committee: Professor Ioan Andricioaei, Chair Professor Douglas Tobias Professor Craig Martens 2014 Appendix A c 2012 American Chemical Society All other materials c 2014 Gavin Dennis Bascom DEDICATION To my parents, my siblings, and to my love, Lauren. ii TABLE OF CONTENTS Page LIST OF FIGURES vi LIST OF TABLES x ACKNOWLEDGMENTS xi CURRICULUM VITAE xii ABSTRACT OF THE DISSERTATION xiv 1 Introduction 1 1.1 Nucleic Acids in a Larger Context . 1 1.2 Nucleic Acid Structure . 5 1.2.1 DNA Structure/Motion Basics . 5 1.2.2 RNA Structure/Motion Basics . 8 1.2.3 Experimental Techniques for Nucleic Acid Structure Elucidation . 9 1.3 Simulating Trajectories by Molecular Dynamics . 11 1.3.1 Integrating Newtonian Equations of Motion and Force Fields . 12 1.3.2 Treating Non-bonded Interactions . 15 1.4 Defining Our Scope . 16 2 The Nanosecond 28 2.1 Introduction . 28 2.1.1 Biological Processes of Nucleic Acids at the Nanosecond Timescale . 29 2.1.2 DNA Motions on the Nanosecond Timescale . 32 2.1.3 RNA Motions on the Nanosecond Timescale . -
MEMS Metrology Metrology What Is a Measurement Measurable
Metrology • What is metrology? – It is the science of weights and measures • Refers primarily to the measurements of length, MEMS Metrology wetight, time, etc. • Mensuration- A branch of applied geometry – It measure the area and volume of solids from Dr. Bruce K. Gale lengths and angles Fundamentals of Micromachining • It also includes other engineering measurements for the establishment of a flat, plane reference surface What is a Measurement Measurable Parameters • A measurement is an act of assigning a • What do we want to • Pressure specific value to a physical variable measure? • Forces • The physical variable becomes the • Length or distance •Stress measured variable •Mass •Strain • Temperature • Measurements provide a basis for • Friction judgements about • Elemental composition • Resistance •Viscosity – Process information • Roughness • Diplacements or – Quality assurance •Depth distortions – Process control • Intensity •Time •etc. Components of a Measuring Measurement Systems and Tools System • Measurement systems are important tools for the quantification of the physical variable • Measurement systems extend the abilities of the human senses, while they can detect and recognize different degrees of physical variables • For scientific and engineering measurement, the selection of equipment, techniques and interpretation of the measured data are important How Important are Importance of Metrology Measurements? • In human relationships, things must be • Measurement is the language of science counted and measured • It helps us -
Thermometry (Temperature Measurement)
THERMOMETRY Thermometry ................................................................................................................................................. 1 Applications .............................................................................................................................................. 2 Temperature metrology ............................................................................................................................. 2 The primary standard: the TPW-cell ..................................................................................................... 5 Temperature and the ITS-90 ..................................................................................................................... 6 The Celsius scale ................................................................................................................................... 6 Thermometers and thermal baths .......................................................................................................... 7 Metrological properties ............................................................................................................................. 7 Types of thermometers.............................................................................................................................. 9 Liquid-in-glass ...................................................................................................................................... 9 Thermocouple .................................................................................................................................... -
Comparison of Responses of Tattoos to Picosecond and Nanosecond Q-Switched Neodymium:YAG Lasers
STUDY Comparison of Responses of Tattoos to Picosecond and Nanosecond Q-Switched Neodymium:YAG Lasers CDR E. Victor Ross, USN; George Naseef, MD; Charles Lin, PhD; Michael Kelly, MS; Norm Michaud, MS; Thomas J. Flotte, MD; Jill Raythen; R. Rox Anderson, MD Objective: To test the hypothesis that picosecond la- ated with the study (and blinded to the treatment type) ser pulses are more effective than nanosecond domain evaluated photographs to assess tattoo lightening. For- pulses in clearing of tattoos. malin-fixed specimens were examined for qualitative epi- dermal and dermal changes as well as depth of pigment Design: Intratattoo comparison trial of 2 laser treat- alteration. Electron micrographs were examined for par- ment modalities. ticle electron density and size changes (in vivo and in vitro). The gross in vitro optical density changes were Setting: A large interdisciplinary biomedical laser labo- measured. ratory on the campus of a tertiary medical center. Results: In 12 of 16 tattoos, there was significant light- Patients: Consecutive patients with black tattoos were ening in the picosecond-treated areas compared with enrolled; all 16 patients completed the study. those treated with nanosecond pulses. Mean depth of pigment alteration was greater for picosecond pulses, Intervention: We treated designated parts of the same but the difference was not significant. In vivo biopsy tattoo with 35-picosecond and 10-nanosecond pulses from specimens showed similar electron-lucent changes for 2 neodymium:YAG lasers. Patients received a total of 4 both pulse durations. In vitro results were similar for treatments at 4-week intervals. All laser pulse param- both pulse durations, showing increases in particle sizes eters were held constant except pulse duration. -
Tunable Temporal Gap Based on Simultaneous Fast and Slow Light in Electro-Optic Photonic Crystals
Tunable temporal gap based on simultaneous fast and slow light in electro-optic photonic crystals Guangzhen Li, Yuping Chen, ∗ Haowei Jiang, Yi'an Liu, Xiao Liu and Xianfeng Chen State Key Laboratory of Advanced Optical Communication Systems and Networks, Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China ∗[email protected] Abstract: We demonstrated a tunable temporal gap based on simul- taneous fast and slow light in electro-optic photonic crystals. The light experiences an anomalous dispersion near the transmission center and a normal dispersion away from the center, where it can be accelerated and slowed down, respectively. We also obtained the switch between fast and slow light by adjusting the external electric filed. The observed largest temporal gap is 541 ps, which is crucial in practical event operation inside the gap. The results offer a new solution for temporal cloak. OCIS codes: (160.2100) Electro-optical materials; (160.4330) Nonlinear optical materials; (060.5060) Phase modulation; (230.3205) Invisibility cloaks. References and links 1. M. W. McCall, A. Favaro, P. Kinsler, and A. Boardman, “A spacetime cloak, or a history editor,” Journal of optics 13, 024003 (2011). 2. M. Fridman, A. Farsi, Y. Okawachi, and A. L. Gaeta, “Demonstration of temporal cloaking,” Nature 481, 62–65 (2012). 3. R. W. Boyd and Z. M. Shi, “Optical physics: How to hide in time,” Nature 481, 35–36 (2012). 4. K. D. Wu and G. P. Wang, “Design and demonstration of temporal cloaks with and without the time gap,” Opt. Express 21, 238–244 (2013). -
Modeling of Atomic Clock Performance and Detection of Abnormal Clock Behavior
WITH) STATES APARTMENT OF NBS TECHNICAL NOTE 636 COMMERCE PUBLICATION Modeling of Atomic Clock Performance and Detection of Abnormal Clock Behavior U.S. APARTMENT OF COMMERCE National Rureau loo Js U51S3 i<?9 3 NATIONAL BUREAU OF STANDARDS 1 The National Bureau of Standards was established by an act of Congress March 3, 1 901 . The Bureau's overall goal is to strengthen and advance the Nation's science and technology and facilitate their effective application for public benefit. To this end, the Bureau conducts research and provides: (1) a basis for the Nation's physical measure- ment system, (2) scientific and technological services for industry and government, (3) a technical basis for equity in trade, and (4) technical services to promote public safety. The Bureau consists of the Institute for Basic Standards, the Institute for Materials Research, the Institute for Applied Technology, the Center for Computer Sciences and Technology, and the Office for Information Programs. THE INSTITUTE FOR BASIC STANDARDS provides the central basis within the United States of a complete and consistent system of physical measurement; coordinates that system with measurement systems of other nations; and furnishes essential services leading to accurate and uniform physical measurements throughout the Nation's scien- tific community, industry, and commerce. The Institute consists of a Center for Radia- tion Research, an Office of Measurement Services and the following divisions: Applied Mathematics — Electricity — Mechanics — Heat — Optical Physics —