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COMBINED LIST of DRUGS THAT PROLONG QT AND/OR CAUSE TORSADES DE POINTES (TDP) Crediblemeds® Has Reviewed Available Evidence

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COMBINED LIST of DRUGS THAT PROLONG QT AND/OR CAUSE TORSADES DE POINTES (TDP) Crediblemeds® Has Reviewed Available Evidence COMBINED LIST OF DRUGS THAT PROLONG QT AND/OR CAUSE TORSADES DE POINTES (TDP) CredibleMeds® has reviewed available evidence for the drugs on the following list and place them in one of three designated categories: Known Risk of TdP (KR), Possible Risk of TdP (PR) or have a Conditional Risk of TdP (CR). The full description of these categories can be found on the CredibleMeds.org website. Generic Name Brand Name Generic Name Brand Name Generic Name Brand Name Alfuzosin (PR) Uroxatral Cilostazol (KR) Pletal Eribulin mesylate (PR) Halaven Amantadine (CR) Symmetrel and others Ciprofloxacin (KR) Cipro and others Erythromycin (KR) E.E.S. and others Amiodarone (KR) Cordarone and others Cisapride (KR) Propulsid Escitalopram (KR) Cipralex and others Amisulpride (CR) Solian and others Citalopram (KR) Celexa and others Esomeprazole (CR) Nexium and others Elavil (Discontinued 6/13) and Clarithromycin (KR) Biaxin and others Ezogabine (Retigabine) Amitriptyline (CR) Potiga and others others (PR) Clomipramine (PR) Anafranil Amphotericin B (CR) Fungilin and others Famotidine (PR) Pepcid and others Clozapine (PR) Clozaril and others Anagrelide (KR) Agrylin and others Felbamate (PR) Felbatol Cocaine (KR) Cocaine Apomorphine (PR) Apokyn and others Fingolimod (PR) Gilenya Crizotinib (PR) Xalkori Aripiprazole (PR) Abilify and others Flecainide (KR) Tambocor and others Cyamemazine Tercian Arsenic trioxide (KR) Trisenox (cyamepromazine) (PR) Fluconazole (KR) Diflucan and others Artenimol+piperaquine (PR) Eurartesim Dabrafenib (PR) Tafinlar Fluoxetine (CR) Prozac and others Asenapine (PR) Saphris and others Dasatinib (PR) Sprycel Flupentixol (PR) Depixol and others Astemizole (KR) Hismanal Degarelix (PR) Firmagon Fluvoxamine (CR) Faverin and others Atazanavir (CR) Reyataz and others Delamanid (PR) Deltyba Furosemide (frusemide) Lasix and others (CR) Atomoxetine (PR) Strattera Desipramine (PR) Pertofrane and others Galantamine (CR) Reminyl and others Azithromycin (KR) Zithromax and others Deutetrabenazine (PR) Austedo Garenoxacin (CR) Geninax Bedaquiline (PR) Sirturo Dexmedetomidine (PR) Precedex and others Gatifloxacin (KR) Tequin Bendamustine (PR) Treanda and others Diphenhydramine (CR) Benadryl and others Gemifloxacin (PR) Factive Bendroflumethiazide or Disopyramide (KR) Norpace Aprinox bendrofluazide (CR) Granisetron (PR) Kytril and others Dofetilide (KR) Tikosyn Bepridil (KR) Vascor Grepafloxacin (KR) Raxar Dolasetron (PR) Anzemet Bortezomib (PR) Velcade and others Halofantrine (KR) Halfan Domperidone (KR) Motilium and others Bosutinib (PR) Bosulif Haldol (US & UK) and Donepezil (KR) Aricept Haloperidol (KR) others Buprenorphine (PR) Butrans and others Doxepin (CR) Sinequan and others Hydrochlorothiazide (CR) Apo-Hydro and others Cabozantinib (PR) Cometriq Dronedarone (KR) Multaq Hydrocodone - ER (PR) Hysinglaâ„¢ ER and others Capecitabine (PR) Xeloda Droperidol (KR) Inapsine and others Hydroxychloroquine (CR) Plaquenil and others Ceritinib (PR) Zykadia Efavirenz (PR) Sustiva and others Hydroxyzine (CR) Atarax and others Chloral hydrate (CR) Aquachloral and others Eliglustat (PR) Cerdelga Ibogaine (KR) None Chloroquine (KR) Aralen Epirubicin (PR) Ellence and others Ibutilide (KR) Corvert Chlorpromazine (KR) Thorazine and others Iloperidone (PR) Fanapt and others If list is printed, check website at www.crediblemeds.org • Please see Disclaimer below • List continued over Generic Name Brand Name Generic Name Brand Name Generic Name Brand Name Imipramine (melipramine) (PR) Tofranil Ondansetron (KR) Zofran and others Sertraline (CR) Zoloft and others Indapamide (CR) Lozol and others Osimertinib (PR) Tagrisso Sevoflurane (KR) Ultane and others Isradipine (PR) Dynacirc Oxaliplatin (KR) Eloxatin Solifenacin (CR) Vesicare Itraconazole (CR) Sporanox and others Oxytocin (PR) Pitocin and others Sorafenib (PR) Nexavar Ivabradine (CR) Procoralan and others Paliperidone (PR) Invega and others Sotalol (KR) Betapace and others Ketanserin (PR) Sufrexal Palonosetron (PR) Aloxi Sparfloxacin (KR) Zagam Ketoconazole (CR) Nizoral and others Panobinostat (PR) Farydak Sulpiride (KR) Dogmatil and others Lansoprazole (CR) Prevacid Pantoprazole (CR) Protonix and others Sultopride (KR) Barnetil and others Lapatinib (PR) Tykerb and others Papaverine HCl (Intra-coronary) Sunitinib (PR) Sutent none (KR) Lenvatinib (PR) Lenvima Tacrolimus (PR) Prograf and others Paroxetine (CR) Paxil and others Leuprolide (PR) Lupron and others Nolvadex(discontinued 6/13) and Tamoxifen (PR) Pasireotide (PR) Signifor others Levofloxacin (KR) Levaquin and others Pazopanib (PR) Votrient Telaprevir (CR) Incivo and others Levomepromazine (KR) Nosinan and others Pentamidine (KR) Pentam Telavancin (PR) Vibativ Levomethadyl acetate (KR) Orlaam Perflutren lipid microspheres (PR) Definity and others Telithromycin (PR) Ketek Levosulpiride (KR) Lesuride and others Perphenazine (PR) Trilafon and others Terfenadine (KR) Seldane Lithium (PR) Eskalith and others Pilsicainide (PR) Sunrythm Terlipressin (KR) Teripress and others Imodium and many other OTC Loperamide (CR) and Rx brands Pimavanserin (PR) Nuplazid Terodiline (KR) Micturin and others Melperone (PR) Bunil and others Pimozide (KR) Orap Tetrabenazine (PR) Nitoman and others Mesoridazine (KR) Serentil Pipamperone (PR) Dipiperon (E.U) and others Thioridazine (KR) Mellaril and others Methadone (KR) Dolophine and others Piperacillin/Tazobactam (CR) Tazosyn and Zosyn Tiapride (PR) Tiapridal and others Metoclopramide (CR) Reglan and others Posaconazole (CR) Noxafil and others Tipiracil and Trifluridine (PR) Lonsurf Metronidazole (CR) Flagyl and many others Probucol (KR) Lorelco Tizanidine (PR) Zanaflex and others Midostaurin (PR) Rydapt Procainamide (KR) Pronestyl and others Tolterodine (PR) Detrol and others Mifepristone (PR) Korlym and others Promethazine (PR) Phenergan Toremifene (PR) Fareston Mirabegron (PR) Myrbetriq Propofol (KR) Diprivan and others torsemide (CR) Demadex and others Mirtazapine (PR) Remeron Prothipendyl (PR) Dominal and others Desyrel (discontinued 6/13) and Trazodone (CR) others Moexipril/HCTZ (PR) Uniretic and others Quetiapine (CR) Seroquel Trimipramine (PR) Surmontil and others Moxifloxacin (KR) Avelox and others Quinidine (KR) Quinaglute and others Tropisetron (PR) Navoban and others Necitumumab (PR) Portrazza Quinine sulfate (CR) Qualaquin Valbenazine (PR) Ingrezza Nelfinavir (CR) Viracept Ranolazine (CR) Ranexa and others Vandetanib (KR) Caprelsa Nicardipine (PR) Cardene Ribociclib (PR) Kisqali Vardenafil (PR) Levitra Nilotinib (PR) Tasigna Rilpivirine (PR) Edurant and others Vemurafenib (PR) Zelboraf Norfloxacin (PR) Noroxin and others Risperidone (PR) Risperdal Venlafaxine (PR) Effexor and others Nortriptyline (PR) Pamelor and others Ritonavir (CR) Norvir Voriconazole (CR) VFend Nusinersen (PR) Spinraza Romidepsin (PR) Istodax Vorinostat (PR) Zolinza Ofloxacin (PR) Floxin Roxithromycin (KR) Rulide and others Note: Medicines on this list are reviewed on an ongoing basis to assure that the available evidence supports their continued placement onZiprasidone this list. (CR) Because, the listGeodon changes and others regularly, we recommendOlanzapine (CR)always checking theZyprexa website and others at crediblemeds.org for the mostSaquinavir up-to-date (PR) information.Invirase(combo) Most drugs have multiple brand names and it is not practical to list them on this form. The Zotepine (PR) Losizopilon and others CredibleMeds.orgOmeprazole (CR) website providesLosec and a otherspartial list of the more common brands.Sertindole (PR) Serdolect and others Disclaimer and Waiver: The information presented here is intended solely for the purpose of providing general information about health-related matters. It is not intended for any other purpose, including but not limited to medical advice and/or treatment, nor is it intended to substitute for the users’ relationships with their own health care providers. To that extent, by use of this list and the information it contains, the user affirms the understanding of the purpose and releases AZCERT, Inc. from any claims arising out of his/her use of this list. The Terms of Use Agreement for this list and the CredibleMeds website is available at https://www.crediblemeds.org/terms. The absence of drugs from these lists should not be considered an indication that they are free of risk of QT prolongation or torsades de pointes. Few medicines have been tested for this risk in patients, especially those with congenital long QT syndrome. This list and the CredibleMeds® website are intended for personal and professional use only and are protected by U.S. Copyright (title 17, U.S. Code). Unauthorized commercial use is prohibited. Generated: August 24, 2017. List last revised: August 23, 2017.
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