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The Millennium Development Goals Our contribution Roche’s contribution to the Millennium Development Goals

The Millennium Development Goals (MDGs) are eight international development goals that the member states have agreed to achieve by the year 2015. The goals include:

1. Ending poverty and hunger 2. Achieving universal primary education 3. Promoting gender equality and empowering women 4. Reducing child mortality 5. Improving maternal health 6. Combating HIV/AIDS, malaria and other diseases 7. Ensuring environmental 8. Forming global partnerships for development

As an industry, healthcare companies are in a strong position to support the MDGs. Aligned with Roche’s core business goals of improving human health and finding sustainable solutions, our contributions can make a lasting impact on global health, changing the lives of individuals and communities.

Through our commitment to developing innovative medicines and diagnostics that will help patients live longer, better lives and through specific initiatives, Roche is contributing towards the global drive to achieve each of these goals.

Activities that are enabling us to do this span the areas of:

• Sustainable patent and pricing policies • Education, training, knowledge-transfer and capacity building • Partnerships with governments, NGOs and other organisations • R&D into diseases with high unmet medical need

The following table provides examples of Roche’s activities and initiatives. In all that we do we focus our energies on the areas in which we can use our expertise and add value. These range from humanitarian and social projects centred mainly in Least Developed Countries (LDCs), to initiatives to increase access to medicines and diagnostic tests, globally.

Further details about these programmes can be found on our website: www.roche.com/access_programmes

Roche’s contribution to the Millennium Development Goals 1 Roche initiative/activity Millennium Development Goal 1 2 3 4 5 6 7 8 Brief End poverty Universal Gender Reduce child Improve Combat Environmental Global partnership Name and hunger education equality mortality maternal health HIV/AIDS, malaria sustainability for development description and other diseases Accelerating We are a founding member Supporting Supporting Partnering with Access of the Accelerating Access sustainable access sustainable access the Accelerating Initiative Initiative, which aims to to HIV care and to HIV care and Access Initiative provide sustainable access treatment treatment members (AAI) to HIV care and treatment in resource limited countries. AmpliCare We provide vital HIV tests Supporting early Supporting Supporting access Partnering with at substantially reduced diagnosis of access to testing to tests to monitor the Clinton prices to SSA$, South HIV infection in for HIV/AIDS effectiveness Foundation HIV/ Africa and LDCs*, along children, enabling and monitoring of of antiretroviral AIDS Initiative with training and lab early intervention treatment therapy for HIV/ (CHAI) and strengthening. AIDS and screen- UNICEF ing for resistant strains of TB

CARE We support the Pharma- Providing free, Providing free Partnering with programme Access Foundation to pro- comprehensive anti-retroviral PharmaAccess vide antiretroviral treatment clinical care and treatment, along Foundation and education to a cohort education to with education, of HIV/AIDS patients in women with HIV/ counselling Africa, along with support AIDS and awareness for knowledge exchange on HIV/AIDS meetings among patients and associated and healthcare professionals. diseases

Changing We work in partnership Supporting Supporting Partnering with Diabetes in with Novo Nordisk and educational provision of care Novo Nordisk, the the World Diabetes initiatives to enable for children with World Diabetes Children Foundation to help self-management type 1 diabetes Foundation and children with type-1 of diabetes today, with the local governments diabetes in developing aim to build and key opinion countries through therapy infrastructure to leaders supplies, education support all people and training healthcare with diabetes professionals.

KEY Sustainable policies • Partnerships * Least Developed Countries, as defined by the UN • Capacity building R&D # Low Income Countries, as defined by the Roche’s contribution to the Millennium Development Goals 2 • • § Sub-Saharan Africa Roche initiative/activity Millennium Development Goal 1 2 3 4 5 6 7 8 Brief End poverty Universal Gender Reduce child Improve Combat Environmental Global partnership Name and hunger education equality mortality maternal health HIV/AIDS, malaria sustainability for development description and other diseases Children’s We hold the Roche Supporting the Supporting Supporting Supporting the Partnering with Walk Children’s Walk every year provision of access to edu- access to edu- provision of food, local communities, to enable our employ- food, clothing, cation, training cation, training clothing, mosquito the European ees to join together to education and and meeting and meeting the nets, education Coalition of raise money to support practical skills the basic needs basic needs (food, and practical skills Positive People HIV/AIDS orphaned training to HIV/ of vulnerable shelter, hygiene training to HIV/ (ECPP) and children in Malawi and AIDS orphans in children and clean water) AIDS orphans in UNICEF vulnerable children in the Malawi of vulnerable Malawi. Includes Switzerland communities proximate to children group sessions our sites around the world. and programmes Please see also ‘Malawi on HIV/AIDS AIDS orphan programme’. prevention

Chocos We have been supporting Supporting Supporting the Supporting Supporting Partnering with Village the village of San Cristóbal increased supply of school the building of construction of the residents of de Chocos in Peru since agriculture, equipment to safer houses 41 houses built Chocos village an earthquake destroyed diversified village children for families, to anti-seismic and damaged much of the livestock and reducing poverty standards, a dam village in 2007. This ongo- thereby provision and hunger and to provide water ing support is designed to of food to those providing year year round plus improve health, nutrition affected by the round access to a water tank and and food security, rebuild earthquake clean water irrigation systems houses, reduce the risk of further earthquake dama- ge and reduce poverty.

EDUCARE We work in partnership Supporting Supporting Supporting Partnering with the International education and education and education and with IAEA and Atomic Energy Agency training to improve training to improve training to improve extended links (IAEA) to help address screening, diag- screening, diag- screening, diag- to their project the significant shortage nosis and treat- nosis and treat- nosis and treat- collaborators of trained healthcare ment of cancer ment of cancer ment of cancer workers in oncology in SSA$.

KEY Sustainable policies • Partnerships * Least Developed Countries, as defined by the UN • Capacity building R&D # Low Income Countries, as defined by the World Bank Roche’s contribution to the Millennium Development Goals 3 • • § Sub-Saharan Africa Roche initiative/activity Millennium Development Goal 1 2 3 4 5 6 7 8 Brief End poverty Universal Gender Reduce child Improve Combat Environmental Global partnership Name and hunger education equality mortality maternal health HIV/AIDS, malaria sustainability for development description and other diseases Einstein- We work in partnership Supporting Supporting Supporting Partnering with Ethiopia with the Albert Einstein education and education and education and Albert Einstein Oncology College of Medicine training to improve training to improve training to improve College of to provide training for screening, diag- screening, diag- screening, diag- Medicine and Collaboration Ethiopian oncology nosis and treat- nosis and treat- nosis and treat- through them, healthcare professionals, ment of cancer ment of cancer ment of cancer development and to improve cancer of a network awareness and patient of provider navigation. institutions

Google We have donated our Supporting efforts Partnering with collaboration medical research, to reduce the Google.org sequencing expertise burden of infect- and instrumentation to ious diseases in Google.org to support East Africa a multidisciplinary surveillance, research and response system for emerging infectious diseases in East Africa.

Haiti School We are supporting a Supporting Supporting Supporting the Partnering with Building school rebuilding project access to edu- access to edu- development Swiss Agency for based near the epicentre cation by building cation for girls and building of Development and of the Haitian earthquake new, safer by building new, prototype schools Cooperation of 2010, in the towns of schools safer schools to anti-seismic Léogane and Petit-Guâve. standards A key component of the prototype blueprint for the new school calls for anti-seismic construction to protect against future earthquakes.

KEY Sustainable policies • Partnerships * Least Developed Countries, as defined by the UN • Capacity building R&D # Low Income Countries, as defined by the World Bank Roche’s contribution to the Millennium Development Goals 4 • • § Sub-Saharan Africa Roche initiative/activity Millennium Development Goal 1 2 3 4 5 6 7 8 Brief End poverty Universal Gender Reduce child Improve Combat Environmental Global partnership Name and hunger education equality mortality maternal health HIV/AIDS, malaria sustainability for development description and other diseases International We provide funding to Supporting Supporting the Supporting the Supporting the Supporting the Partnering with Committee support the International the ICRC to ICRC to provide ICRC to provide ICRC to provide ICRC to repair or ICRC Committee of Red Cross provide water to water, avoiding clean water to clean water to drill wells and deep of Red Cross (ICRC) water projects communities in high safety and communities, communities, boreholes equipped (ICRC) in Africa, which aim rural areas and security risks of helping prevent helping prevent with pumping and Clean Water to provide water for areas of conflict seeking water, the spread of the spread of storage to provide Project inhabitants in rural areas, especially to disease disease water, creating or or areas of conflict, thereby women maintaining sustain- avoiding displacement and able living environ- reducing safety risks of ments and preven- populations. ting the displace- ment of populations

Malawi Through initiatives such Supporting the Supporting the pro- Supporting Supporting the Supporting the Partnering with AIDS orphan as the Roche Children’s provision of vision of education participation in provision of food, provision of food, the European Walk, we have raised food, clothing, and training to HIV/ education and clean water and clean water, Coalition of programme funds to support five education AIDS orphans; ena- training for HIV/ clothing to HIV/ clothing, mosquito Positive People centres for HIV/AIDS and practical bling the construc- AIDS orphans, AIDS orphans nets, education (ECPP) and orphans, build classrooms skills training tion of classrooms including girls and practical skills UNICEF and facilitate access to to HIV/AIDS and improvement training to HIV/ Switzerland primary, secondary and orphans of school facilities AIDS orphans. post-secondary educa- to maximise partici- Includes group tion and practical skills pation in education; sessions and pro- training. provide learning grammes on HIV/ material; training lo- AIDS prevention cal student teachers

Non profit We provide two Supporting Supporting pricing antiretroviral medicines increased access increased access at no profit prices to to HIV medicines to HIV medicines LDCs*, LICs# and SSA$, in LDCs*, LICs# in LDCs*, LICs# representing 63 countries and SSA$ and SSA$ globally. In addition, we provide Valcyte (to combat cytomegalovirus retinitis) at a reduced price to NGOs treating patients with AIDS.

KEY Sustainable policies • Partnerships * Least Developed Countries, as defined by the UN • Capacity building R&D # Low Income Countries, as defined by the World Bank Roche’s contribution to the Millennium Development Goals 5 • • § Sub-Saharan Africa Roche initiative/activity Millennium Development Goal 1 2 3 4 5 6 7 8 Brief End poverty Universal Gender Reduce child Improve Combat Environmental Global partnership Name and hunger education equality mortality maternal health HIV/AIDS, malaria sustainability for development description and other diseases No patent We do not file or enforce Supporting Supporting policy any patents on our medi- access to access to cines in the LDCs* or LICs#. medicines in medicines in In addition, we do not enforce LDCs*, LICs# and LDCs*, LICs# and patents for antiretrovirals SSA$ SSA$ in SSA$, the region poorest and hardest hit by HIV/ AIDS.

OneWorld We have provided the Supporting the Supporting the Partnering with Health Institute for OneWorld development of development of the Institute for Collaboration Health with access to the new treatments to new treatments to OneWorld Health compounds in our library combat diarrhoea combat diarrhoea to support their R&D ef- in developing in developing forts to find a medicine to countries countries treat diarrhoea, a leading cause of mortality in child- ren under five years of age in developing countries.

Pakistan We are helping to fund Supporting Supporting Supporting the Partnering with School the building of a new access to edu- access to edu- development the Citizens critically needed school cation by building cation for girls and building Foundation Building in Jacobabad, one of the new, safer by building new, of prototype areas affected by the de- schools safer schools schools vastating floods of 2010. and assuring female faculty

Pandemic We help specified Supporting Supporting Partnering with Preparedness/ developing countries access to governments the World Health to prepare for influenza paediatric to respond Organization Tamiflu pandemics through the formulations of effectively to and national programme Tamiflu Pandemic Reserves Tamiflu an influenza governments Programme. We also have pandemic a tiered pricing policy to assist governments with pandemic preparedness.

KEY Sustainable policies • Partnerships * Least Developed Countries, as defined by the UN • Capacity building R&D # Low Income Countries, as defined by the World Bank Roche’s contribution to the Millennium Development Goals 6 • • § Sub-Saharan Africa Roche initiative/activity Millennium Development Goal 1 2 3 4 5 6 7 8 Brief End poverty Universal Gender Reduce child Improve Combat Environmental Global partnership Name and hunger education equality mortality maternal health HIV/AIDS, malaria sustainability for development description and other diseases Roche Interested, eligible Secondments Secondments Secondments Partnering with Secondment employees identify in partner in partner in partner governmental, Programme assignments and non organisations, organisations organisations, multi-lateral and profit partner organisations working to working to working to non-government where they can make a improve child improve maternal combat HIV/ organisations, as meaningful and sustainable health health AIDS, malaria and appropriate to the contribution to help other diseases secondment prevent and/or manage a health related issue on one of the poorest countries of the world. Roche makes them available for up to 12 months (fully paid)

Transnet We are the main external Supporting the Supporting Supporting Supporting the Partnering Phelophepa sponsor of Transnet- health of school the delivery of community delivery of vital with Transnet Phelophepa, a unique children through health checks education on health education Foundation Train primary healthcare clinic visits to schools, and medical general health and promotion to on wheels that travels into health checks treatment to issues, such as rural South Africa, areas of rural South Africa and community children; provid- hygiene and including HIV/ to provide healthcare to education about ing community nutrition; delivers AIDS awareness communities where there key health topics education to vital health checks, is often just one doctor such as nutrition improve nutrition medicines and for every 5,000 people. and hygiene and hygiene education to remote villages

Technology We launched the AIDS Supporting Supporting Transfer Technology Transfer access to generic access to generic Initiative in 2006 to versions of our versions of our Initiative share our knowledge HIV medicines HIV medicines about manufacturing our and increasing and increasing HIV protease inhibitor local capacity local capacity saquinavir, and provide to develop and to develop and hands-on guidance to local manufacture manufacture other manufacturers from LDCs* other medicines medicines and those within SSA$.

KEY Sustainable policies • Partnerships * Least Developed Countries, as defined by the UN • Capacity building R&D # Low Income Countries, as defined by the World Bank Roche’s contribution to the Millennium Development Goals 7 • • § Sub-Saharan Africa