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Drug Discovery Modern Therapeutics MPCST SPONSORED National Seminar DRUG DISCOVERY THROUGH REVERSE PHARMACOLOGY & ITS TRANSFORMATION INTO MODERN THERAPEUTICS CURRENT STATUS, CHALLENGES & OPPORTUNITIES 27th March 2017 ABSTRACT BOOK Organized By Acropolis Institute of Pharmaceutical Education and Research www.aiper.ac.in Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities ABOUT THE INSTITUTE Acropolis Institute of Pharmaceutical Education & Research (AIPER) is nurtured by Teach for India Education & Research Society having objective of creating state of art, world class and high quality technical education facilities at Indore. Towards fulfilment of its objective society established AIPER in the year 2008. AIPER is a philanthropic organization sprawled in an area of around 2 acres and is committed to the service of humanity through technological advancement. The institute offers Masters degree in Pharmaceutics and Bachelor’s degree in Pharmacy. The institute is approved by AICTE, New Delhi, PCI & CPCSEA and is affiliated to Rajiv Gandhi Technical University (RGPV), Bhopal. Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities GROUP CHAIRMAN’S MESSAGE I am feeling immense pleasure to know that Acropolis Institute of Pharmaceutical Education & Research is going to organize MPCST Sponsored National Seminar on “Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities” on 27th March 2017. The seminars, conferences act as a platform for academicians, industrialist, research scholars and students for sharing knowledge of drug discovery in the area of Pharmaceuticals, Cosmetics, Neutraceuticals and Allied segments. I send my greetings and best wishes to the local organizing committee and all the participants for the grand success of seminar and also the deliberations. I also extend my best wishes for all the academic lectures and the scientific session. Mr. Ashish Sojatia Group Chairman Acropolis Indore (M.P.) Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities PRINCIPAL’S MESSAGE It gives me immense pleasure in welcoming all the dignitaries, speakers and delegates to the MPCST Sponsored National Seminar on “Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities” on behalf of Acropolis Institute of Pharmaceutical Education & Research. There could have not been any more relevant theme for National seminar in Pharmaceutical sciences to know the proper utilization of traditional knowledge, modern tools in discovering novel lead molecules from plants by employing Reverse Pharmacology techniques. I hope this seminar will open up the discussion to help up the entire participant in the field of recent development in drug discovery. The seminar will definitely help and open a new area of research to the researchers by utilizing traditional medicinal knowledge. I wish the seminar to be a thought provoking, intellectually stimulating event, igniting the minds of participants for drug discovery and development through Reverse Pharmacology. I also take this opportunity in thanking MPCST for sponsoring this event. Dr. G.N. Darwhekar Principal AIPER Indore (M.P.) Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities ABOUT SEMINAR Reverse pharmacology is the science of integrating documented clinical experiences and experiential observations into leads by transdisciplinary exploratory studies and further developing these into drug candidates or formulations through robust preclinical and clinical research. In recent years the revived scientific interest in plant-derived natural product-based drug discovery has been observed due to scientific and technological advances in the relevant research fields. The present seminar will highlight issues related to the proper utilization of traditional knowledge, modern tools in discovering novel lead molecules from plants by employing reverse pharmacology techniques. The seminar will definitely help and open a new area of research to the researchers by utilizing traditional medicinal knowledge. OBJECTIVES OF THE SEMINAR The objective of the proposed seminar is to understand the role of medicinal plants in discovery of new drugs which will provide a new area of research to understand and explore the plethora of medicinal plants and traditional knowledge for its transformation into modern therapeutics to achieve the goal of “Health For All”. TOPICS TO BE DISCUSSED Drug Discovery status in India Country’s contribution in the drug development Detailed process of drug discovery from lab to market including the time and cost involved at each stages Challenges involved in the plant origin drug discovery and its regulatory status including the patentability Country’s Scope and opportunity in the current scenario. etc Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities CHIEF GUEST Dr. Shailendra Saraf Vice- President, Pharmacy Council of India GUEST OF HONOURS & INVITED SPEAKERS Mr. Sanjay Tiwari Vice President, Sun Pharmaceutical Industries Ltd. Dr. Swarnalata Saraf Professor, University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) Vice- President, Association of Pharmacy Teachers in India Dr. Manish Wanjari Scientist 2, Regional Ayurveda Research Institute for Drug Development, Gwalior, CCRAS, Ministry of AYUSH, Government of India Dr. Adnan Naim Department of Bioscience and Biomedical Engineering, IIT Indore Dr. C Karthikeyan Assistant Professor, School of Pharmaceutical Sciences, RGPV Bhopal Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities ORGANIZING COMMITTEE CHIEF PATRONS Shri Ashok Sojatia Shri Ashish Sojatia PATRONS Prof. M.K. Dube Dr. Shamsher Singh TECHNICAL ADVISOR Dr. D.K. Jain Director, COP, IPS Academy ORGANIZING CHAIRMAN Dr. G.N. Darwhekar CONVENER Mr. Praveen Sharma CO- CONVENER Mr. Ashish Gupta REGISTRATION SCIENTIFIC WEB & MEDIA COMITTEE COMMITTEE Dr. Kunjbihari Sulakhiya Mr. Vikas Jain Ms. Lata Sharma Ms. Priyanka Joshi Ms. Ankita Mane Ms. Ritu Soudawat Ms. Priyanka Mishra Ms. Archana Patidar Ms. Akanksha Dwivedi Ms. Rakhi Khabiya STAGE HOSPITALITY COMMITTEE COMMITTEE Mr. Mukul Sharma Mr. Ravi Sharma Ms. Anamika Singh Mr. Anupam Mishra Organizing Institute Acropolis Institute of Pharmaceutical Education & Research, Indore Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities SEMINAR PROCEEDINGS Acropolis Institute of Pharmaceutical Education & Research, Indore MPCST SPONSORED National Seminar on Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities TIME EVENT 8:30AM-9:30AM REGISTRATION & BREAKFAST 9:30AM-10:30AM PREINAUGRAL SESSION 10:30AM-11:30AM INAUGURAL CEREMONY 11:30AM-12:30PM SCIENTIFIC SESSION I 12:30PM- 1:30PM SCIENTIFIC SESSION II 1:30PM-2:00PM LUNCH 2:00PM-3:00PM SCIENTIFIC SESSION III 3:00PM-4:00PM POSTER PRESENTATION 4:00PM-5:00PM VALEDICTORY 5:00PM-5:30PM HIGH TEA Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities Acropolis Institute of Pharmaceutical Education & Research, Indore Drug Discovery through Reverse Pharmacology & its Transformation into Modern Therapeutics: Current Status, Challenges & Opportunities INDEX ABSTRACT TITLE PRESENTING NO. AUTHOR PREDICTION OF SITE OF METABOLISM FOR CYTOCHROME Dr. Elangovan PP-01 P450 1A2 LIGANDS AND VIRTUAL SCREENING MODELS Manivannan DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF 3-(2- PP-02 OXO-2-ARYLETHYLIDENE)INDOLIN-2-ONES AS POTENTIAL Dr. C. Karthikeyan ANTI-BREAST CANCER AGENTS RATIONALIZATION OF MOLECULAR DESCRIPTORS OF PP-03 CYCLIC-UREA DERIVATIVES AS HIV PROTEASE INHIBITORS: Dr. M.C.Sharma A QSAR STUDIES EFFECT OF ACACIA NILOTICA L. ON DRUG INDUCED SEXUAL PP-04 Dr. Neelesh Malviya DYSFUNCTION IN MALE RATS. STRUCTURE-BASED VIRTUAL SCREENING AND IN-SILICO ADMET PROFILING ON PTP1B RECEPTOR FOR Mr. Neelesh PP-05 IDENTIFICATION OF POTENTIAL CELL PERMEABLE Maheshwari INHIBITORS OF NOVEL ANTI DIABETIC AGENT 3D-QSAR STUDIES OF 3-[4-(1H-IMIDAZOL-1-YL) PHENYL] PP-06 Ms. Ritu Soudawat PROP-2-EN-1-ONES AS ANTILEISHMANIAL AGENTS FORMULATION AND EVALUATION OF PLURONIC LECITHIN PP-07 Ms. Prerana Mishra ORGANOGEL OF LORNOXICAM FOR TOPICAL DELIVERY. SPECTROPHOTOMETRIC ESTIMATION OF TOTAL TANNIN PP-08 Dr. Vishal Soni CONTENT IN SOME AYURVEDIC EYE DROPS IN-VITRO ANTIUROLITHIATIC ACTIVITY OF ALCOHOLIC AND PP-09 HYDROALCOHOLIC EXTRACTS OF KALANCHOE PINNATA Dr. Priyanka Soni LEAVES IN VITRO SCREENING OF ETOPOSIDE HYDROGEL
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