Emolivan™ Natural W/O cold cream base

Fagron Advanced Derma Leading advanced dermatological care

With Fagron Advanced Derma, patients offered a total solution for both customized prescription compounding and basic skin care based on:

• Vehicle design according to the latest scientific insights into the tolerance of ingedients used in dermatology • Different bases for different skin types • Suitability for vulnerable, sensitive skin • Optimal compatibility with a broad range of APIs and DCIs • Example formulations are provided for help with prescribing and compounding

Total solution Discover Fagron Advanced Derma’s total solution by accessing the various information resources: • Fagron Advanced Derma brochure • Vehicle brochures • Compatibility table Emolivan™ cream base • Quality documents • Compounding Matters formulations Emolivan™ cream base is a natural W/O cold Benefits of Emolivan™ cream base database cream base containing a unique, natural, oil- • Innovative water-in-natural oil cold • Fagron Academy based emuisifier. Emolivan™ cream base is cream base • FACTS (Fagron Academy Compounding often used in patients with (very) dehydrated • Borate-free formulation with natural Technical Services) and/or affected skin because of its unique oil-based emulsifier fagron.us hydration effects. Designed according to the • Rich in omega-6 and vitamin E latest insights into the tolerance of ingredients • Non-greasy skin feel and readily vanishing used in dermatology. Emolivan™ cream base • Excellent protection and hydration effects is formulated without harmful, obsolete, and • Especially suitable for (very) dehydrated controversial ingredients. Emolivan™ is an and affected skin ideal compounding vehicle for a broad range • Unique water-absorbing property for of active pharmaceutical ingredients (APIs) and flexible compounding dermaceutical ingredients (DCIs). • Compatible with a broad range of APIs and DCIs • Simple three-step compounding process fagron.us Example Formula. Nocompounded medication isreviewedthe FDA by for safety orefficacy. References available upon request. fromto any any formulationto anythe sameorsimilar whollyor inpart person(includingdeath) is to result that or alleged injury resulting orclaimed responsible for any claims, actions, liabilities, losses, expenses, damages, orcosts judgment orrelated orindirectly arisingdirectly inanyto any way actual this Exampleto Formula.respect Fagron,that Customer understandsandagrees itsowners, Inc., officers, agents, affiliatesnotbe andemployees shall of any formula contained within.Fagron, itsowners, Inc., officers, agents, affiliates andemployees make no representation or warranty whatsoever with Disclaimer: FACTS (Fagron Academy Compounding Please refer to theCompounding Matters database at fagron.us for more formulations orlearnmore about agents: water, glycerin, propanediol orsunflower oil. For anoptimalmixture solidAPIsandDCIsin Emolivan™ of cream addq.s. base, thefollowing oneof of wetting Emolivan™ cream base Example compounding formulations for base cream Emolivan™ • Fagron Advanced Dermaoffers a total solution for: Emolivan™ cream base Compounding andbasicskincare with Please refer to theFagron Advanced Dermacompatibility tablefor more vehicle andAPI/DCIcombinations. Example APIsandDCIscompatible withEmolivan™ cream base: guarantees maximumpatient comfort for optimalcompliance andresults. Provides continuous care for theskinduringexacerbation andmaintenance phasesand • Diclofenac sodium Diclofenac Dexpanthenol B12) (vit. Cyanocobalamin (liquor carbonis detergens) solution tar Coal lithanthracis) (pix crude tar Coal Clotrimazole propionateClobetasol Ciclopirox olamine extract Chamomile valerate dipropionate Benzyl HCl Arginine Anthralin/dithranol lactate Ammonium Alpha bisabolol extract vera Aloe API/DCI in Emolivan™ cream base 5% Glycerol 5% acid Salicylic in Emolivan™ cream base 1% acetate Basic skincare Customized pharmaceutical compounding Above are examples ofsome commonly prescribed formulations across adiverse arrayto encourage ofspecialties, meant the use andisnot

Tel. 423 (800) 6967 -Fax 339 (800) 1596 [email protected] Fagron, -2400 Pilot Knob Inc. Road Paul, -St. Minnesota 55120 - USA 3% 5% to 0.5 0.25% 0.1% to 0.05 0.07% 20% 5 to 10% 1 to 2% 1 to 0.05% 1% 5% to 0.5 0.1% to 0.025 0.05% 25% 2.5% 3% to 0.05 12%1 to 5% to 0.5 10% to 0.5 concentration(s) Common Technical Services) @fagronacademy.us/facts. in Emolivan™ cream base 20% oxide Zinc in Emolivan™ cream base 2.5% Glycerol 2.5% HCI Arginine

Zinc sulfate Zinc Zinc oxide Urea acetonide Tocopherol E) (vit. Tacrolimus Sulfur butter Shea acid Salicylic Permethrin B3) (vit. Nicotinamide furoate Menthol HCl Lidocaine acid Lactic acetate Hydrocortisone Hydrocortisone Glycerol acetonide valerate API/DCI in Emolivan™ cream base Tocopherol in Emolivan™ cream base Tacrolimus 0.3%

(vit. E) (vit. 1 to 3% 1 to 5% to 0.5 10% 1 to 2% 2.5% to 0.25 2.5% to 0.25 20% to 0.5 0.1% to 0.01 0.1 0.3% to concentration(s) Common 1 to 10% 1 to 40% 1 to 10% 5 to 0.1% to 0.025 20% to 0.5 0.5% 0.03 to 10% 5 to 20% 1 to 20% to 0.5 5% 5% 2 to 0.1% 5%

Basic skincare withEmolivan dehydrated andaffected skin. cream baseisidealfor basicskincare for (very) The innovative formulation Emolivan™ of cream base fagron.us 3. 2. 1. method compounding simple three-step Time-saving,

Very dehydrated skin Dehydrated skin Affected skin cream baseto final weight andmix well. suitable solvent. consistency. Levigate thepowder with Geometrically addsufficient Emolivan™ Reduce allpowder(s) to uniform, fine Calculate andweigh eachingredient. ™

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