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The Most Influential People in Vaccines in People Influential Themost

The Most Influential People in Vaccines in People Influential Themost

The Most Influential People in in People Influential TheMost

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Prior to this, she was an adjunct an associatewas adjunct she this, to Prior preventable disease. - Michael was appointed Director of MHRP in January 2006, guided and founded Vanda pharmaceuticals, which had completed a $200 million million $200 a completed had which pharmaceuticals, Vanda founded Michael, Michael, a Colonel in the United StatesArmy Medical Corps, entered his - Dr. MHRP through the completion theof RV144 prime HIV , an international collaboration that involved more than 16,000 Thai volunteers, provided the world’s first demonstration that a preventive HIV vaccine possible.was Dr Army service in in 1989WRAIR's Departmentof Vaccine Research. Dr Santosham is a professorof and Pediatric Infectious Diseases at Johns Hopkins, as well as professorof , International Health and at the Johns Hopkins BloombergSchool Public of Health. He is a renowned expertin renowned. and Apache Indian populations including Hib, Hepatitis rotavirusA, and pneumococcal vaccines. Sabin Gold Medal for his work to prevent H. Chip Clark joined Genocea Biosciences in 2010 as president. Prior to this, he this, to Prior president. as 2010 in Biosciences Genocea joined Clark Chip co company the helped Clark At Genocea, 2010. in with deal licensing round fundingB Series million $35 a secure of CEO named was he 2011, In companies. pharmaceutical other and Johnson to using is it which far, so million $61 raised has company The Genocea. programs vaccine five advance In 2013 Karen Ernst re2013Ernst In Karen and officials doctors, by scientists, supported organization parents that provides vaccine St at literature English of professor Ernst Johns Hopkins Bloomberg School of Public of School Bloomberg Hopkins Johns Health Karen Karen Leader Vaccines for Voices Dr Mathuram Santosham Director, Health systemsProgram Director, Centre for American Indian Health Professorof International Health and Pediatrics Chip Chip Clark Chief and President executive Officer Genocea Biosciences Dr Dr Nelson Michael Research HIV Military US Director, Program Institute Army Reed Walter 47 49 50 48 The Most Influential People in Vaccines Shot of vaccine vaccine foundation, a - immunisation immunisation vaccine. research and Shot@Life Institute of Medicine, and UK’s national UK’s Vaccinate Your Baby, and Advisory Committee on whose career has been devotedto virologist John John F. Enders at Children’s Hospital where and Every Child Every Child Two, by has also been invited to participate with other pro the widely now used attenuated addition to his UK responsibilities, he works extensively with extensively heworks responsibilities, UK his to addition paediatrician . In . is a American American AcademyPediatrics, of the the WHO on the Global Programme for Vaccines. He was Chairman of the of Chairman was He Vaccines. for Programme Global theon WHO the to 2010, 2005 from Vaccines on Experts of Group Advisory Strategic WHO Poliomyelitis for Commission Certification Region European the of Chairman is for Commission Certification Elimination of member a is and Eradication, regions. WHO further two Professor David Salisbury is responsible for the for responsible is Salisbury David Professor programme Mark Lacy is the founder and CEO of Benchmark Research, a clinical trials a clinical Research, Benchmark and ofCEO the founder is Lacy Mark company 1997,expanding the has founding in its Since provider. service now to Texas, Worth Fort in just services trial clinical providing from the United across centers in research6 dedicated services providing magazine by Entrepreneur a finalist as selected 2010,he was In States. 2010. of Entrepreneur the Established as Dr Katz infectious disease research, focusing principally on vaccine development. has He chaired the Committeeon Infectious Diseases of the Practices the at CDC, the Vaccine Priorities Studyat the several WHO and CVI vaccine panels.and HIV Earlier in his careerDr Katz worked with Nobel Laureate they developed Ms Butler startedthe Nurses Who Vaccinate Facebook in page2011 and continues useto it respondto to online parenting forums that publicize inaccurate information vaccines. about Her initiatives caught the attention of Wall The Street Journal, and she organizations, including Prevention. She is also a global health champion for the United Nations campaign to immunize children around the globe. xecutive Officer xecutive E Mark Lacy Chief Benchmark Research Pediatric Nurse Pediatric Good Samaritan Hospital Medical Centre, Lindenhurst, NY Melody Melody Ann Butler Dr Dr Samuel Katz WilburtCornell Professor, Davison Chairmanofand Emeritus Pediatrics Dr Dr David Salisbury ofDirector Immunization UK Department of Health 44 43 45 46 The Most Influential People in Vaccines - - national coming coming to created newly Prior tothis, Dr response tothe a the Director for the associated place. Before - as history, new vaccines new against , of in in U.S. the University of Guelph in in Guelph of University the at is Principal Investigator of the NIH the of Investigator Principal is as the first director of the vaccines positions at Transgene, and the Institut led the US’s effortdevelop to and . 2008 Robinson previously served volume volume of Information, Evidence Research.and Dr Dr Edwards Dr Dr Robinson HHS. influenza influenza in developing countries all took is an expert in vaccinology, with numerous publications in in the publications numerous with in vaccinology, an expert is Doctoral Associate Doctoral - Advanced Researchand Development Authority (BARDA),and Deputy funded Clinical Immunization Safety Assessment (CISA) Network. (CISA) Assessment Immunization Safety Clinical funded A.Monteiro is a professor is A.Monteiro - . pandemic Robinson was appointedin Dr Edwards Dr the of member Aand influenza. pneumococcus, pertussis, of fields Medicine, of Institute and (VTEU)and Treatment Evaluation Vaccine Unit Vanderbiltfunded CDCthe Canada. His latest research has covered various vaccines, including a including vaccines, various covered has research latest His Canada. and 1 trial, human phase clinical entered a which has vaccine, Diarrhea an bolteae, Clostridium for targeta vaccine students 4 M.Sc students, 3 PhD includes team research His bacterium. and a Post Appointed in November 2012, Dr Kieny was previously WHO Assistant Director General for Innovation, Kienydirected the WHO Initiative for Vaccine Research since its inception in 2001.Under her leadership the development and WHO, Dr Kieny held topresearch la de santé etde la recherche médicale (INSERM). Dr Biomedical Assistant Secretary in the Office theof Assistant Secretaryfor Preparednessand Responsewithin manufacture the largest pandemic. H1N1 2009 Influenza Emerging & Disease Program within and itsBARDA predecessoragency at HHS Dr Maro Dr General General of - Paule Kieny Paule - esearch Program Research and Development Research and Development Authority US Department of Health and Human Services Dr Dr Marie Director Assistant Innovation and Systems Health HeathWorld Organisation Robinson Dr Robin Advanced Biomedical Director, Dr Dr Mario Monterio and ofVaccines Professor Carbohydrates ofUniversity Guelph, Ontario Vanderbilt University Vanderbilt Dr Dr Kathryn Edwards and ofPediatrics, Professor Vaccine Vanderbilt Director, R 40 41 42 39 The Most Influential People in Vaccines - to and junior and junior Washington, policy, and focused Worldwide Business Business Worldwide and immune and immune therapies. students, fellows, vaccines Immunology Immunology has at the University of presentations published, prior prior published, presentations based - 1988, moving on to on moving 1988, in in domestic international and immunogenicity. immunogenicity. the areaMolecular of scientific papers and papers scientific Dr Neuzil Dr Neuzil held positions in in the first to vaccines moveDNA to clinical human studies University, positions was Pierre Préziosi contributed documentation on epidemic meningitis - joined GSK Vaccines in Vaccines GSK joined With over 100 over With Pierre Préziosi was appointed director of the PATH/WHO Meningitis - Weiner’s research Dr extensively on the developmentgene of His laboratory establishing their initial safety and He is also activevery in teaching and training of faculty. chairs He the popular Gene Therapy and Vaccines Programat the University of Pennsylvania, and co directs the Tumor Programof the Abramson Cancer Center at the University Pennsylvania. of R&D in 2006. He was also given overall responsibility for GSK's Oncology Oncology GSK's for responsibility overall given also was He 2006. in R&D in Franchises Global all for and 2011; in Vaccines GSK for 2010; in Business 2012. Mons, of University the at Immunology of Professor was Moncef GSK, joining . Dr Neuzil directs PATH’s activities that focus on developing and advancing strategies, technologies, and interventions that help move research achievements in immunization into routine use in the field. has She provided technical and leadership guidance for vaccine projects including work rotaviruson a vaccine, JapaneseHPV, encephalitis influenza. and Prior to joining PATH, Vanderbilt and membership on the advisory CDC committee on immunisation practices. Marie Vaccine Project in March member of2012. A the MVPsince team 2003, Marie Pierre Préziosi mosthad recently served as director of clinical development for MVP as parther of role as medical officer at WHO. In her early years with MVP, Marie and related vaccine use forinforming development meningococcala ofnew A and introduction strategies. As MenAfriVac moved theto clinical phase, she to appointedwas lead MVP clinical research activities. Dr Moncef Dr to lead appointment his before products pharmaceutical for Development Pierre Preziosi - Dr Kathleen Dr Neuzil Kathleen Access Vaccine Leader, Program Delivery and PATH Dr Dr and Chairman,Research Development GlaxoSmithKline Dr Dr David Weiner and ofPathology Professor Medicine Laboratory ofUniversity Pennsylvania Project Director ofDirector Meningitis the Project Project Vaccine HeathWorld Organisation & PATH Dr Dr Marie 37 38 35 36 The Most Influential People in Vaccines to hospital. Development Development keep polio at polio keep bioinformatics and Vanderbilt , and polio rubella , 2015 reviewed scientific research - is a physician and . thirds by thirds - work in polio eradication, humanitarian introduce four new vaccines as partof as vaccines new four introduce and expanded to offer immunogenicity immunogenicity to offer expanded and Programme. Programme. to founded EpiVax in 1998 to use to 1998 in EpiVax founded the WHO's and founded a free clinic in Rhode Island, Clinica Clinica Island, Rhode in clinic free a founded and vaccines, vaccines, decision decision Martin cooperation. DrAylward has authored overpeer 100 together driven driven - treatment, in some districts. in some Graham is the Deputy Director of the National Institute of Institute National the of DeputyDirector the is Graham 2014the ) vaccines will drive India towards their Millennium Millennium their India towards drive will vaccines ) . reduce child mortality by two mortality child reduce AIDS Groot and Bill Bill and Groot to In addition, an adult vaccine against Japanese encephalitis will be will an encephalitis vaccine against addition,adult Japanese In of July July of Aylward brings rd Dr response and country epidemiologist. He papers, as well as book chapters on immunisation. He joined the WHO in 1992 as a Medical Officer, worked7 yearswhere he forwith national immunisation programmes across the globe. Since 1998, he has been responsible for overseeing and coordinating all polio eradication activities across WHO’s Global polio Eradication Initiative Partnership. Dr De Dr epitope design therapeutics protein for services screening medical providing program Prison in HIV theYale to contributed also has She improving for Foundation Vaccine GAIA the founded to inmates, treatment global Esperanza Dr Barney Dr Chief as positions held has he this, to Prior Disease. and Infectious Allergy and the hospital General Metro both at the Resident and even he significant, were research and HIV AIDSto contributions His resident chief as Tennessee in AIDS of cases two firstthe on of diagnosed General. Metroat India’s Universal Immunization Immunization Universal India’s (injectable Goal bay. introduced The current Prime Minister of India, Shri Narendra Modi, announced announced on Modi, the Narendra India, Shri of Minister Prime The current 3 accine Research accine General for Polio Polio General for V - founder, Chief Executive ChiefExecutive founder, - Deputy Director, Director, Deputy Centre National Institute of Allergy and Infectious Disease (NIAID) Dr Dr Annie Groot De Co Chief Officer Scientific Officer, EpiVax Dr Barney Graham Mr Shari Narendra Modi Shari Narendra Mr of Minister Prime India World HeathWorld Organisation Dr Dr Director Assistant Country and emergencies Collaboration 32 33 31 34 The Most Influential People in Vaccines . Dr . he was also e . In 2002, H Vaccine Vaccine . VP of of VP years. In 2000 antivirals. antivirals. GSK France an Gellin was the director of director the was Gellin Dr Therapeutics President Designate of GSK vaccines vaccines CDC’s Antiviral Drug Program Drug Antiviral CDC’s date, authoritative information about information authoritative date, - has been to - of the of influenza influenza in in term as President in Spring 2012. joining NVPO in 2002, in NVPO joining been with with been GSK Vaccines forthan more 17 began his 2006. Prior to this, he has had more than 15 years of than 15years had has more he this, to 2006.Prior President and Regional Director, Asia Pacific at GlaxoSmithKline - in in , an immunologist in training, was appointed appointed was training, in immunologist an , held the position of Senior Research Scientist and Project Manager, and Project Scientist Research Senior of position held the Bruce Gellin is one of the US’s top experts on vaccines and vaccines infectious on expertstop the US’s of one is Gellin Bruce Kim, Kim, a Colonel in the United StatesArmy Medical Corps, started his military Kim’s research interests include molecular HIV epidemiology, hostgenetics, Dr and leadershipprovide to by Congress created was NVPO diseases. immunization and agencies other among Federal coordination Before stakeholders. organization he an Information, Immunization for Network National the up of resource be a to founded and vaccines . Dr career in the Air Force, assigned theto Department of Retroviral Research. After a brief exodus, he enteredservice Army in in 2000the Departmentof HIV Vaccine Research, Division Retrovirology,of WRAIR. Dr and HIV vaccine development. He servesreviewer as a for scientific journals and has served on consultations for the World Health Organization theand Global HIV/AIDS Vaccine Enterprise. Dr Weber has appointed as Vice President and Operations Director of Weber was appointedVice President and then servedas Chairman and CEO of GlaxoSmithKline France and 2008. between2003 In 2008, he was appointed Senior Vice Singapore. Since January 2011, he Vaccines and Research Research a researcheras experience Branch the Influenza in served Bright Alteaat Programsand Immunology Vaccine Dr Bright Dr World HeathWorld Organisation Dr Dr Bruce Gellin Secretary for Assistant Deputy ofDirector Health Nation the Office (NVPO) Program Vaccine Dr Dr Jerome Kim Chief, and Director Deputy Department of Virology Molecular Pathogenesis and US Military HIV Research Program (MHRP) Dr Dr Christophe Weber Unit Vaccines President, GlaxoSmithKline Dr Dr Research Vaccine President, Vice Novavax 27 29 28 30 Melinda Gates is co-chair of the Bill & Melinda Gates Foundation. Along with co-chair , she shapes and approves the strategic direction of the Melinda Gates foundation. From gun violence to , the foundation has pumped billions Co-Chair and Trustee into the world’s poorest and most vulnerable areas, including billions of the Bill and Melinda Gates Gate’s personal funds. The foundation has poured millions into both R&D as well Foundation as increasing vaccine coverage across the world. Their commitment to vaccines 26 has seen collaborations with Sanofi Pasteur and GSK investigating thermostability, as well a $138m investment in vaccine R&D.

Dr Jadhav is the Executive Director of the Serum Institute of India, one of the largest vaccine manufacturers in the world. He also led the development and Dr Suresh Jadhav introduction of a Meningococcal A conjugate vaccine in sub-Saharan Africa. Dr Executive Director Jadhav was president of the Developing Countries Vaccine Manufacturers’ Network (DCVMN) from 2003-2008. He is currently a member of GAVI Board, Serum Institute of India EVI Board of Stakeholders, FastVac, member of the Program & Policy Committee 25 of GAVI. He is also associated with ’s Task Force, WHO IVR and Decades of Vaccines.

Dr John Shiver is the Senior Vice-President of Research and Development Vaccines in People Influential TheMost Dr John Shiver at Sanofi Pasteur. He also serves as Vice-President of Worldwide Basic Senior Vice-President of Research Research and Franchise Head of Vaccines at Merck. He leads a team working to develop novel vaccines against a broad range of diseases, and Development including HIV/AIDS, human papillomavirus, zoster, influenza and 24 Sanofi bacterial . He has co-authored 24 patents covering vaccine development.

Anthony S. Fauci is an immunologist who has made substantial Dr contributions to research in the areas of HIV/AIDS and other Director , both as a scientist and as the head of the NIAID. He oversees an extensive research portfolio of basic and applied research National Institute of Allergy and to prevent, diagnose, and treat infectious diseases such as HIV/AIDS and 23 Infectious Diseases (NIAID) other sexually transmitted infections, influenza, tuberculosis, malaria and illness from potential agents of . Dr Farshad Guirakhoo is the Chief Scientific Officer of Hookipa Biotech AG, a vaccine biotech start up pioneering a new class of vaccines. DrGuirakhoo Dr Farshad Guirakhoo is a trained virologist, and has spent more than twenty years working with Chief Scientific Officer biotech’s and large pharmaceutical companies. Prior to joining Hookipa, Hookipa Biotech AG DrGuirakhoo was Senior Director of External Research and Development at 22 Sanofi Pasteur. Before joining Sanofi, he worked for vaccine biotech Acambis for 15 years, where he headed research.

Dr Kathrin Jansen is the Senior Vice President and Chief Scientific Officer of Dr Kathrin Jansen Vaccine Research and Early Development at . In 2006, she joined as senior vice president, which is now part of Pfizer. In this role, she Senior Vice President and Chief supported the paediatric licensure of Prevnar 13, as well as its adult Scientific Officer licensure. Her and her team have created a vaccine against Staphylococcus 21 Pfizer aureus, which is now in phase 2. Prior to joining Wyeth, Dr Jansen was the

Chief Scientific Officer of VaxGen. The Most Influential People in Vaccines in People Influential TheMost

Dr Akira Homma Dr Akira Homma is the current chairman of Bio-Maguinhos, based in Brazil. Previously, he was the president for the Japan Society for Chairman Dementia Care. He was also a board member of the Japan Society for 20 Bio-Magnuinhos Geriatric Psychiatry. He studied medicine in Japan, graduating in 1973.

Mr Erck was appointed President and CEO of Novavax in April 2011. From 2000-2008, he was president and CEO of lomai corporation. He led the Stanley Erck company through to IPO and a merger with Intercell, an Austrian vaccine President and Chief Executive company. He also led the company through the development of an infectious Officer disease product candidate. Prior to lomai, Mr Erck was President and CEO of Novavax Procept, and before this held positions at Genzyme and Baxter International. 19 He attended the University of Illinois for his undergraduate degree, and recived his MBA from the University of Chicago Graduate School of Business. Dr Manon Cox, President and CEO of the Protein Science Corporation, joined the company in 1998 as Director of Business Development. She also serves on Dr Manon Cox the Scientific Advisory Boards of Pall BioPharmaceuticals and iCubed, the Board President and Chief Executive of Directors of United Way, Meriden & Wallingford, and the Netherlands- Officer America Foundation and its Education Committee. Previously, she was with Gist- Protein Science Corporation Brocades, a Dutch company specialising in fermentation. Prior to Gist-brocades, 18 she worked as a Molecular Biologist on the development of a PCR screening test for cervical cancer at the University of Amsterdam.

Dr Reiss is a Professor at the University of California Hastings College of Law. Dr Reiss has come to the attention of the vaccines industry through her outspoken Dr Dorit Reiss defence of vaccines on the internet. From writing about the legal rights of Professor of Law unvaccinated children, through engaging with the fierce anti-vaccine mob. University of California, Hastings Ageofautism.com even have a page dedicated to her… College of Law Dr Reiss received her Ph.D from the Jurisprudence and Social Policy program in 17 UC Berkeley. Her research is currently focused on legal issues related to vaccines, including exemption laws and tort liability to non-vaccination.

Cynthia Dukes, VP and therapeutic and operations advisor for ICON, has over Vaccines in People Influential TheMost Cynthia Dukes 35 years of diverse clinical experience. After practicing as a medical Vice President, Global Project technologist in general laboratory medicine and as a PA in primary care, Management Vaccines and Cynthia began her research career as the clinical team leader at Baylor Oncology Centre of Excellence College of Medicine’s vaccine and Respiratory Diseases Research Center. After 16 this, she joined Sanofi Pasteur for ten years. Throughout her career, she has ICON supported multiple IND submissions and product approvals.

Cyrus Poonawalla Cyrus Poonawalla is the Chairman of the Poonawalla Group, which owns Chairman the Serum Institute of India. The Serum Institute of India is the world’s largest producer of vaccines, making more than a billion doses annually Poonawalla Group, including the from a factory in Pune, western India. He is listed by Forbes as being the 15 Serum Institute of India 10th richest man in India. Making a strong leap from #50 last year, down to the mid teens in 2014, Ewan McGregor is on a mission to the ends of the earth to immunise some of the Ewan McGregor hardest-to-reach children in the world, following two vaccine trails supported by Actor and UNICEF Ambassador Unicef. After India and Nepal, Ewan’s second mission was in the Republic of Congo where he continued to bring vaccines to families of the most 14 remote and vulnerable areas in the Congo.

Dr Berkley, a medical epidemiologist by training, is the CEO of the GAVI Alliance as well as the former President and CEO of the International AIDS Dr Seth Berkley Vaccine Initiative. Under his leadership, IAVI implemented a global Chief Executive Officer advocacy programme that assured that vaccines receive prominent attention GAVI Alliance in the media and in the political world. Prior to founding IAVI in 1996, Dr 13 Berkley was an officer at The Rockefeller Foundation, worked at the CDC, as well as the Task Force for Child Survival at the .

Steve Davis is the president and CEO of PATH, an international non-profit organisation. His commitment to human rights and global development grew Vaccines in People Influential TheMost Dr Steve Davis from his early work on refugee programs and policies. Before joining PATH, he President and Chief Executive had been the director of social innovation for McKinsey and Company and Officer interim CEO of the Infectious Diseases Research Institute. Steve Davis sits on PATH multiple advisory groups, including the World Economic Forum’s Global Agenda 12 Council on Social Innovation, the Clinton Global Initiative’s Global Health Advisory Board and more.

Dr Ralf Clemens Ralf Clemens, PHD, is the Senior Vice-President at Takeda Senior Vice President Pharmaceuticals Ltd, a position he has held since March 2012, after Takeda working as Head of Global Development Vaccines at Novartis for 6 Advisor to the Bill and Melinda years. Before joining Novartis, he was with Glaxo Smith Kline for 24 11 Gates Foundation years. Dr Emilio Emini Emilio A. Emini, Ph.D., is Senior Vice President and Chief Scientific Officer of Senior Vice President Vaccine Research at Pfizer Inc., a position into which he transitioned subsequent to Pfizer's acquisition of Wyeth Pharmaceuticals in late 2009. Dr Emini joined and Chief Scientific Wyeth as Executive Vice President of Vaccine Research and Development in Officer Vaccine Research November 2005. At Wyeth, he led the R&D efforts that resulted in licensure of 10 Pfizer our second-generation vaccine for the prevention of pneumococcal disease.

Dr Siber was previously Executive Vice President and Chief Scientific Officer of Wyeth Vaccines where he oversaw the development and approval of multiple Dr widely-used childhood vaccines, including Prevnar, the predecessor to Pfizer’s best Executive Chairman selling Prevnar 13. Prior to Wyeth, Dr Siber was Director of the Massachusetts Public Health Biologic Laboratories and a Associate Genocea Biosciences Professor of Medicine at Dana Farber Cancer Institute. Dr Siber is now the 9 executive director and chairman of Genocea’s scientific advisory board, and also sits on a number of PATH committees.

Sadly, Dr Quadros died in May of this year at the age of 74. Before joining Sabin in Dr Ciro de Quadros 2003, Dr de Quadros was the Director of the Division of Vaccines and Immunization at Vaccines in People Influential TheMost Executive VP, Director of the Pan American Health Organization. He also served as the World Health vaccine Advocacy and Organization's Chief Epidemiologist for the Smallpox Eradication Program in Ethiopia from 1970 to 1976 where he implemented a nationwide “surveillance and Education containment” strategy, a world first. Dr Quadoros is often credited with having 8 Sabine Vaccine Institute eradicated smallpox single-handedly from Brazil, measles from the Americas, and polio in Latin America.

Dr Paul A. Offit is a professor of vaccinology and paediatrics at the University of Dr Pennsylvania. He is also Chief of the Division of Infectious Diseases at the Children’s Director, Vaccine Hospital of Phildaelphia. Dr Offit specialises in infectious diseases and is an expert on Education Centre vaccines, immunology, and virology. He is the co-inventor of a that has Children’s Hospital been credited with saving hundreds of lives every day. Previously he was a member of 7 of the CDC advisory committee on immunisation practices. Dr Offit is also a board member of , and a founding member of the Autism Science Foundation. Dr Stan Plotkin Dr Orin Levine Emeritus Professor Director of vaccine Delivery University of Pennsylvania Bill and Melinda Gates Adjunct Professor Foundation 6 5

Dr Levine is the Executive Director of the International Vaccine Access Dr is Emeritus Professor of the University of Center, the co-chair of the Pneumococcal Awareness Council of Experts Pennsylvania and Adjunct Professor of John Hopkins University. Dr (PACE), and he is a professor at the John Hopkins Bloomberg School of Plotkin is also a member of the scientific advisory board for Hookipa Public Health. Dr Levine also serves as Director of Vaccine Delivery at the Biotech. Bill and Melinda Gates Foundation, where he leads the Foundation’s efforts to accelerate the introduction of new vaccines and related technologies and Until 1991, he was Professor of Pediatrics and at the to improve routine immunization systems around the world. University of Pennsylvania, Professor of Virology at the Wistar He is the Foundation’s focal point for engagement with the GAVI Alliance, Institute and at the same time, Director of Infectious Diseases and whose mission is saving children’s lives by increasing access to immunization Senior Physician at the Children’s Hospital of Philadelphia. In 1992, in poor countries. Previously, Dr Levine was the President the American he left the University to join the vaccine manufacturer Pasteur-Mérieux

Society of Tropical Medicine and Hygiene. Dr Levine received his Connaught, where for seven years he was Medical and Scientific Vaccines in People Influential TheMost undergraduate Bachelors degree from in Gettysburg, Director. Pennsylvania. He continued his studies at the John Hopkins Bloomberg School of Public Health, where he received a PhD in epidemiology. After The same company is now named Sanofi Pasteur. He is now consultant receiving his PhD, he worked for the CDC as an epidemic intelligence to vaccine manufacturers, companies and non-profit service officer. research organizations. Earlier in his career, he did an internship at Previously, Dr Levine has been President of the Committee on Global Health Cleveland Metropolitan General Hospital, a in paediatrics at the American Society of Tropical Medicine & Hygiene as well as Co- at the Children’s Hospital of Philadelphia and the Hospital for Sick Chair of the Pneumococcal Awareness Council of Experts (PACE). Children in London and three years in the Epidemic Intelligence Dr Levine regularly writes about health issues and news for the Huffington Service of the Centers for Disease Control of the US Public Health Post. He has co-authored over 70 research papers covering pneumonia and Service. meningitis, and has written book chapters about these topics too. Dr Stephen Hoffman Dr Rino Rappuoli Founder, Chief executive Officer, Head of R&D Chief Scientific Officer Novartis Vaccines 4 3 Sanaria

Rino Rappuoli is Global Head of Vaccines Research at Novartis Vaccines Dr Hoffman is the Founder, and Chief Executive and Scientific Officer of and Diagnostics. Prior to this he was head of Research & Development at Sanaria Inc., a company dedicated to developing a whole sporozoite Sclavo and then head of vaccine research and Chief Scientific Officer of . Chiron Corporation. Rappuoli has spent his career developing vaccines for pertussis, meningitis, and Helicobacter pylori and is jointly responsible for From 1987-2001 he was Director of the Malaria Program at the Naval engineering the carrier protein used in many conjugate vaccines. Center where he and his team were leaders in the sequencing of the Plasmodium falciparum genome and conducted the first Several molecules he worked with became part of licensed vaccines, studies in the world that showed that DNA vaccines elicited killer T cells in including: CRM197 used in H. influenzae, N. meningitides and humans. pneumococcus vaccines; an acellular vaccine against pertussis containing a genetically detoxified pertussis toxin; the first conjugate vaccine against In 2001 Dr Hoffman retired from the Navy and joined Celera Genomics as meningococcus C and later against meningococcus ACYW; the MF59 used Senior Vice President to create a program to utilize genomics and Vaccines in People Influential TheMost in a vaccine against pandemic influenza; and the genome-derived vaccine proteomics to produce new biopharmaceuticals. He established this against meningococcus B currently under review by European and program and organized the effort that sequenced the genome of the Canadian regulatory agencies. mosquito responsible for most transmission of malaria in Africa, Anopheles gambiae. He left Celera in August 2002 to found Sanaria. He is the most He was elected a member of the US National Academy of Sciences and the highly cited author in the world for scientific papers on malaria published European Molecular Biology Organization. Awards conferred include: Paul between 1995 and 2005. Ehrlich and Ludwig Darmstaedter Prize (1991), the Gold Medal by the Italian President (2005), the Albert B. Sabin Gold Medal (2009), the Sanaria caught headlines earlier this year after launching a $250,000 Lifetime Achievement Award from the Institute of Human Virology in crowdfunding campaign to help finance a number of mosquito dissecting (2010), and the Excellence Award from the European Society of robots. Whilst ultimately unsuccessful, the campaign demonstrated Sanaria’s Clinical Microbiology and Infectious Diseases (2011). and Hoffman’s innovative approach to development that involves the public in the search for a cure against the worlds biggest killer. Dr Thomas Monath Adjunct Professor Chief Technical Harvard school of Officer 2 Public Health, PaxVax

Dr Monath has devoted his nearly 30-year career to of Vector-Borne Viral Diseases at the Centers for the fight against infectious disease through his work Disease Control; and from 1989 to 1992, he served in the military, corporate, academic and investment as chief of the Virology Division, U.S. Army Medical sectors. In addition to his role at PaxVax, Dr Monath Research Institute of Infectious Diseases. is a Partner in the Pandemic and Biodefense Fund at Kleiner Perkins Caufield & Byers and is a Director of PaxVax currently has a strong and diverse vaccine Sentinext plc, Rapid MicroBiosystems Inc., and U.S. pipeline, aimed squarely at currently unoccupied Biologics Inc. He is also Adjunct Professor at Harvard markets. Using licenced technologies, as well as their School of Public Health. own Ad4/Ad7 vectors and their A549 cell substrate,

the team have vaccines for cholera, H5N1, Anthrax, Vaccines in People Influential TheMost From 1992 to 2006, Dr Monath was Chief Scientific HIV, and Dengue all in the works. Officer and Executive Director at Acambis, which was acquired by Sonofi Pasteur in 2008 for £285m. At Recently, the company has acquired the FDA Acambis, Dr Monath pioneered the development of approved , cure cells Vivotif, which ChimeriVax vaccines against dengue, West Nile, was tied to a successful $62 million funding round. Japanese encephalitis (using yellow fever as a live vector) vaccines against yellow fever, Clostridium difficile, Helicobacter pylori, as well a cell based featured in the US stockpile.

In 1992, Dr Monath retired as a U.S. Army colonel following 24 years in the uniformed services. From 1973 to 1988, he served as director of the Division Bill Gates Co-Chair and Trustee Bill and Melinda Gates 1 Foundation

Bill Gates is co-chair of the Bill & Melinda $28,000,000,000 ($28b) to the foundation. Gates Foundation. Along with co-chair Melinda The foundation operates by the exclusive goal Gates, he shapes and approves grant making of maximising the return on their investment in strategies, advocates for issues focused on by terms of human life. the foundation, and helps set the overall direction of the organization. The foundation has poured millions into both R&D as well as increasing vaccine coverage Bill and Melinda Gates work together to give across the world. Their commitment to vaccines

opportunities to the world’s most has seen collaborations with Sanofi Pasteur and The Most Influential People in Vaccines in People Influential TheMost disadvantaged people by collaborating with GSK investigating thermostability, as well a grantees and partners. Guided by the belief $138m investment in malaria vaccine R&D. that every life has equal value, the Bill & Melinda Gates Foundation works to help all people lead healthy, productive lives. In developing countries, it focuses on improving people’s health and giving them the chance to lift themselves out of hunger and extreme poverty. Vaccines have played a major role in the foundation’s supported initiatives.

As of the May last year, Bill had donated In partnership with

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