Welch Center for Prevention, Epidemiology and Clinical Research

WELCH CENTER FOR PREVENTION, EPIDEMIOLOGY AND CLINICAL RESEARCH ANNUAL REPORT JULY 1, 2007 - JUNE 30, 2008 THE JOHNS HOPKINS MEDICAL INSTITUTIONS THE JOHNS HOPKINS SCHOOL OF MEDICINE THE JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH www.jhsph.edu/welchcenter WELCH CENTER ANNUAL REPORT, 2007-2008 TABLE OF CONTENTS I. MESSAGE FROM THE DIRECTOR . 1 II. EXECUTIVE SUMMARY . 3 III. MISSION STATEMENT AND CORE VALUES . 5 IV. FACULTY AND STAFF . 7 V. SPONSORED PROJECTS . 15 VI. FACULTY PUBLICATIONS . 23 VII. FACULTY PRESENTATIONS: INVITED TALKS AND SCIENTIFIC MEETINGS . 43 VIII. AWARDS AND RECOGNITION . 51 IX. FACULTY TEACHING ACTIVITIES . 53 X. WELCH CENTER TRAINEES . 59 XI. RESEARCH STUDIES . 73 XII. FACULTY EXTERNAL COMMITTEE MEMBERSHIPS . 81 XIII. FACULTY EDITORIAL ACTIVITIES . 89 XIV. CLINICAL RESEARCH GRAND ROUNDS AT THE WELCH CENTER: SPEAKERS AND TOPICS . 91 XV. WELCH CENTER ACTIVITIES LISTING . 95 XVI. FACULTY DIVERSITY DEMOGRAPHICS . 103 MESSAGE FROM THE DIRECTOR I am pleased to summarize the progress of the Welch Center in my eleventh stimulating year as Director. The Welch Center, in its 20thth year, continues to thrive with landmark scholarship and remarkable intellectual rigor. The award-winning faculty and staff continue to embrace core values of collaboration and team building both within and outside the center, creativity and new ideas, mentoring and development, opportunities for leadership, and patient and public health impact. Our annual funding levels of $19.3 million direct costs and well over $25 million in total costs are remarkable in today’s competitive NIH funding climate. This level exceeds that of some departments in our university and many departments in other universities, a testament to the multidisciplinary environment and collaboration we have cultivated over the past several years. The publication productivity of our faculty is outstanding. On average each faculty member publishes five to six manuscripts per year, many of which appear in journals with high impact factors, bearing in mind the limitations of such standards of research quality. In this report, you will also observe the faculty’s dissemination of scholarship in over 97 presentations and invited lectures (domestically and abroad), and their influence in editorial activities and on international, national and regional committees. Our crosscutting scholarship continues in several thematic areas including patient- oriented research, genetic and molecular epidemiology, outcomes research, lifestyle interventions and health behaviors, patient-physician communication and health and healthcare disparities. Through fundamental work we seek scientific solutions to prevent and better manage cardiovascular disease, kidney disease, diabetes and obesity, mental health and substance abuse disorders, and their related consequences. These themes are exemplified in 17 newly funded projects started in 2007-2008: 1) Dr. Anderson’s studies on the effects of dietary sodium and potassium intake on subclinical and clinical cardiovascular disease and 2) tests of a unique biomarker for high fructose corn syrup and 3) for intake of sweets, 4) Dr. Astor’s integrated epidemiologic and toxicologic cardiovascular study, 5) Dr. Boulware’s study of information and financial interventions for kidney donation in African Americans, 6) Dr. Brancati’s patient-oriented research in type 2 diabetes and 7) his study of the epidemiology and prevention of type 2 diabetes and its complications, 8) Dr. Cooper’s study of quality of decision-making communication and outcomes of care for African Americans with depression, 9) Dr. Daumit’s randomized trial of achieving healthy lifestyles in psychiatric rehabilitation, 10) Ms. Fink’s data coordinating centers for the study of childhood development after cochlear implant and for 11) the study of bilateral cochlear implants, 12) Dr. Furth’s mid- career investigator award in patient-oriented research in pediatric kidney disease, 13) Dr. Guallar’s work with the Spanish National Center for Cardiovascular Investigation, 14) Dr. Klag’s longitudinal study of dialysis, 15) Dr. Parekh’s study of the mineralization and cardiovascular disease risk in an incident dialysis cohort, 16) Dr. Powe’s sample frame for the HANDLS Study in the Baltimore area and 17) Dr. Selvin’s study defining the clinical significance of hba1c prior to the onset of diabetes. Welch Center Annual Report -- 1 July 1, 2007–June 30, 2008 We play a major role in developing and training the future generations of clinical and translational researchers across Johns Hopkins, and for other institutions who hire our trainees to do important work in advancing science and the frontiers of clinical investigation. This is admirable work by our faculty in promoting trainees’ development, often over their own. I believe it is a key element in neutralizing destructive forces leading to the decline of physician scientists in the U.S. Having successful and dedicated mentors who are truly engaged in their trainees’ welfare must impact the experiences and future success of our trainees. Our faculty members also remain cornerstones in the School of Medicine and School of Public Health curriculum. In over 85 venues, they reach hundreds of students, teaching scientific principles, methods and tools of population-based medicine that unify medicine and public health. We invite you to join us in any of our activities, particularly Clinical Research Grand Rounds (each Wednesday during the academic year), our seminars and our interest groups. Many new collaborations and projects have been jumpstarted through creative energy sparked by exchanges of scientific passions at the Center. Your scientific breakthrough could be next. Neil R. Powe, MD, MPH, MBA Director 2 -- Welch Center Annual Report July 1, 2007 – June 30, 2008 WELCH CENTER ANNUAL REPORT, 2007-2008 EXECUTIVE SUMMARY Annual Report Section Summary Faculty 30 Faculty Members 8 Professors (as of 6/30/08) 8 Associate Professors 11 Assistant Professors 1 Senior Scientist 1 Associate Scientist 1 Research Associate Sponsored Projects Core faculty members are principal or co-principal investigators on 73 projects ∼ 66% federally funded 17 new in FY07-08 ∼ $ 19,300,000 direct costs in FY07-08 Publications 163 Peer-reviewed manuscripts - 15 in “Highest Impact” Journals - 38 in “Higher Impact” journals Presentations 97 Presentations and invited lectures - 78 presented in the U.S. - 19 presented abroad Awards and Recognition 18 Awards granted and achievements recognized Teaching Directed or co-directed: 24 courses (18 SPH; 6 SOM) Taught in: 61 additional courses (36 SPH; 24 SOM; 1 SON) Trainees 116 Trainees (with a Welch Center primary mentor) - 44 Doctoral students - 71 Master’s students and/or post-doctoral fellows - 1 Other Committees 151 International/National/Regional Committee Memberships Editorial Activities 27 Appointments - 1 Editor-in-Chief - 9 Associate Editorships - 1 Editorial Consultant - 16 Editorial Board Memberships Welch Center Annual Report -- 3 July 1, 2007–June 30, 2008 (This page is intentionally left blank) 4 -- Welch Center Annual Report July 1, 2007 – June 30, 2008 MISSION STATEMENT AND CORE VALUES Mission Statement The primary mission of the Welch Center for Prevention, Epidemiology, and Clinical Research is to generate and disseminate the knowledge required to prevent disease and its consequences and to promote the health of the public. To meet this challenge, the faculty of the Welch Center integrates clinical expertise with comprehensive knowledge of epidemiologic methods. The Welch Center harnesses the talents of a group of faculty, staff, and students dedicated to disease prevention, health promotion, and evidence-based health practices. The Center’s work has three hallmarks. First, it is focused on diseases and conditions that impose a substantial burden on the health and resources of the public. Second, it employs the full range of research methodology, including observational epidemiology, randomized controlled trials and effectiveness, and outcomes research. Third, because biologic, environmental, and clinical factors interact in causing illness and disability, the work is fundamentally interdisciplinary, relying on active collaboration among faculty members from the Schools of Medicine, Public Health, and Nursing. To accomplish its mission, the Welch Center has the following specific aims: • Develop an understanding of the etiology of disease and its consequences in populations; • Evaluate and improve strategies for primary prevention, secondary prevention, and disease management with regard to efficacy, effectiveness, and efficiency; • Translate epidemiologic discoveries into clinical practice and public health policy; • Train future leaders in clinical epidemiology, disease prevention, health promotion, and clinical research. Since it was established in 1989, the Welch Center has been engaged in multidisciplinary clinical and translational research intended to strengthen the practice of medicine, striving for academic excellence in rigorous, evidence-based research that has an impact on patients as well as public health. Symbolic of this intersection between clinical and population-based research, the Center is named after William Henry Welch, the first and only Johns Hopkins Professor to hold positions of Dean of the School of Medicine and Dean of the School of Public Health. Reflecting Dr. Welch’s ability to bridge the disciplines of medicine and public health, the faculty and staff of the Center come from both

Load more